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The map label for this gene is ftsX [H]

Identifier: 94993947

GI number: 94993947

Start: 534243

End: 535202

Strand: Direct

Name: ftsX [H]

Synonym: MGAS10750_Spy0551

Alternate gene names: 94993947

Gene position: 534243-535202 (Clockwise)

Preceding gene: 94993946

Following gene: 94993949

Centisome position: 27.58

GC content: 35.83

Gene sequence:

>960_bases
GTGATGAAGAAAAAGGAGATTATGGTTACGATGATTAGATACTTTTTCCGTCATATTTGGGAATCCATTAAAAATCTTAA
ACGCAACTTTTGGATGACATTTGCTTCAGTTAGTATGGTGGCTGTTACATTGACTTTAGTTGGTGTTTTTGCGGCGACAT
TGTTGAATATACAGCGTGTTGCTTCGGGTGTTGAAAATAATGTCCATATCAATACCTACTTACAAGTTGATTCAACTGAT
GCTGCAAAAGTTATTCAAAATACTGCCGGTGAACCTGTTAATAACGATAACTACCACAGTGTTTACGACAAAATTGCTCA
GATAAAAGGTGTCAAAAAGATTACATTTTCTAGCAAGGATGAACAATTGAAAAAATTGCAAGAAACCTTAGGTGATGTTT
GGAATATGTATGACCAAGACACTAATCCGCTCCAAGATATCTATCTTATTGAGACCCAGACGCCTAAACAAGTTAAGGCG
ATCACTAAAAAGATCAGAACGATTGAAGGCGTAGAAGCCGCAGATTATGGAGGGATTAACTCCGATAAACTATTTAAGTT
TTCAACATTAATTCAAACTTGGGGGTTGATCGGAACAGCAATGCTATTATTTGTAGCTGTCTTTCTCATTTCAAACACTA
TTCGTATGACTATTATGTCTCGTAAACGCGACATTGAAATTATGCGGTTAGTTGGTGCTAAAAATTCTTATATTCGAGGG
CCTTTCTTTTTTGAAGGGGCTTGGGTTGGCTTGTTAGGAGCTGTTTTACCATCTCTTCTGATTTATTATGGATATGATCT
TGTTTATAAGCATTTTGCACAAGAATTACAACGTAATAATCTCTCGATGTATCCGCTTGATCCTTATGTATATTACCTGA
TTGGTGCTTTGTTTGTCATAGGTATTATGATTGGTTCGCTTGGTTCAGTGCTTTCTATGAGACGTTATTTAAAATTCTAA

Upstream 100 bases:

>100_bases
AATGTTCAGGGAACAACTATCTTAATGGCGACACACAACAGTCATATTGTGAATACATTTCGTCATCGTGTTGTTGCTAT
TGAAGATGGTCGCATAGTAC

Downstream 100 bases:

>100_bases
AAAAAGCGCTGCTGACGAAACGTAGCGACCCCCAAAAGTTGGACCTCTTATGTTATTCCAAGGACTTCGTTTTGTATTGC
ACAGGACTGGTCCTTTTCAT

Product: cell division protein ftsX

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 319; Mature: 319

Protein sequence:

>319_residues
MMKKKEIMVTMIRYFFRHIWESIKNLKRNFWMTFASVSMVAVTLTLVGVFAATLLNIQRVASGVENNVHINTYLQVDSTD
AAKVIQNTAGEPVNNDNYHSVYDKIAQIKGVKKITFSSKDEQLKKLQETLGDVWNMYDQDTNPLQDIYLIETQTPKQVKA
ITKKIRTIEGVEAADYGGINSDKLFKFSTLIQTWGLIGTAMLLFVAVFLISNTIRMTIMSRKRDIEIMRLVGAKNSYIRG
PFFFEGAWVGLLGAVLPSLLIYYGYDLVYKHFAQELQRNNLSMYPLDPYVYYLIGALFVIGIMIGSLGSVLSMRRYLKF

Sequences:

>Translated_319_residues
MMKKKEIMVTMIRYFFRHIWESIKNLKRNFWMTFASVSMVAVTLTLVGVFAATLLNIQRVASGVENNVHINTYLQVDSTD
AAKVIQNTAGEPVNNDNYHSVYDKIAQIKGVKKITFSSKDEQLKKLQETLGDVWNMYDQDTNPLQDIYLIETQTPKQVKA
ITKKIRTIEGVEAADYGGINSDKLFKFSTLIQTWGLIGTAMLLFVAVFLISNTIRMTIMSRKRDIEIMRLVGAKNSYIRG
PFFFEGAWVGLLGAVLPSLLIYYGYDLVYKHFAQELQRNNLSMYPLDPYVYYLIGALFVIGIMIGSLGSVLSMRRYLKF
>Mature_319_residues
MMKKKEIMVTMIRYFFRHIWESIKNLKRNFWMTFASVSMVAVTLTLVGVFAATLLNIQRVASGVENNVHINTYLQVDSTD
AAKVIQNTAGEPVNNDNYHSVYDKIAQIKGVKKITFSSKDEQLKKLQETLGDVWNMYDQDTNPLQDIYLIETQTPKQVKA
ITKKIRTIEGVEAADYGGINSDKLFKFSTLIQTWGLIGTAMLLFVAVFLISNTIRMTIMSRKRDIEIMRLVGAKNSYIRG
PFFFEGAWVGLLGAVLPSLLIYYGYDLVYKHFAQELQRNNLSMYPLDPYVYYLIGALFVIGIMIGSLGSVLSMRRYLKF

Specific function: Part of the ABC transporter ftsEX involved in sporulation. May act as an importer, possibly at the top of a hierarchical cascade leading to the correct temporal initiation of sporulation. Acts upstream of the histidine kinases KinA, KinB and KInC, the Rap

COG id: COG2177

COG function: function code D; Cell division protein

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable). Note=Unlike the E.coli ortholog, localization is not restricted to division septa, nor is it dependent on ftsZ [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ABC-4 integral membrane protein family. FtsX subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789872, Length=266, Percent_Identity=25.9398496240602, Blast_Score=81, Evalue=9e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003838 [H]

Pfam domain/function: PF02687 FtsX [H]

EC number: NA

Molecular weight: Translated: 36449; Mature: 36449

Theoretical pI: Translated: 9.89; Mature: 9.89

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.4 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.4 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMKKKEIMVTMIRYFFRHIWESIKNLKRNFWMTFASVSMVAVTLTLVGVFAATLLNIQRV
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ASGVENNVHINTYLQVDSTDAAKVIQNTAGEPVNNDNYHSVYDKIAQIKGVKKITFSSKD
HCCCCCCEEEEEEEEECCCHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCCHHEECCCHH
EQLKKLQETLGDVWNMYDQDTNPLQDIYLIETQTPKQVKAITKKIRTIEGVEAADYGGIN
HHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCHHHHHHHHHHHHHHCCCCHHCCCCCC
SDKLFKFSTLIQTWGLIGTAMLLFVAVFLISNTIRMTIMSRKRDIEIMRLVGAKNSYIRG
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
PFFFEGAWVGLLGAVLPSLLIYYGYDLVYKHFAQELQRNNLSMYPLDPYVYYLIGALFVI
CCEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHH
GIMIGSLGSVLSMRRYLKF
HHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MMKKKEIMVTMIRYFFRHIWESIKNLKRNFWMTFASVSMVAVTLTLVGVFAATLLNIQRV
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ASGVENNVHINTYLQVDSTDAAKVIQNTAGEPVNNDNYHSVYDKIAQIKGVKKITFSSKD
HCCCCCCEEEEEEEEECCCHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCCHHEECCCHH
EQLKKLQETLGDVWNMYDQDTNPLQDIYLIETQTPKQVKAITKKIRTIEGVEAADYGGIN
HHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCHHHHHHHHHHHHHHCCCCHHCCCCCC
SDKLFKFSTLIQTWGLIGTAMLLFVAVFLISNTIRMTIMSRKRDIEIMRLVGAKNSYIRG
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
PFFFEGAWVGLLGAVLPSLLIYYGYDLVYKHFAQELQRNNLSMYPLDPYVYYLIGALFVI
CCEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHH
GIMIGSLGSVLSMRRYLKF
HHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]