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The map label for this gene is ftsW [H]

Identifier: 94993921

GI number: 94993921

Start: 506916

End: 508220

Strand: Direct

Name: ftsW [H]

Synonym: MGAS10750_Spy0525

Alternate gene names: 94993921

Gene position: 506916-508220 (Clockwise)

Preceding gene: 94993920

Following gene: 162139188

Centisome position: 26.17

GC content: 36.78

Gene sequence:

>1305_bases
ATGATTATCTCAAGAAGTAGAGGGAAAACTATGAAGATTGATAAAAGGCACCTCTTAAATTATTCTATATTATTGCCTTA
TTTAATTTTATCGGTGATAGGCTTAATAATGGTTTACTCAACCACAAGTGTCAGCTTGATTCAAGCACATGCTAATCCAT
TTAAATCGGTGATTAACCAGGGAGTTTTTTGGATAATAAGTCTAGTGGCTATTACATTTATCTATAAATTAAAATTAAAT
TTTTTAACGAATACAAGGGTATTAACTGTGGTTATGTTAGGAGAGGCCTTTCTTTTAATTATTGCCCGCTTCTTTACAAC
TGCTATCAAAGGAGCGCATGGTTGGATTGTGATCGGACCAGTCAGCTTTCAGCCTGCTGAGTATTTAAAGATCATTATGG
TATGGTATTTGGCATTGACCTTTGCTAAGATCCAAAAAAACATTAGCCTTTATGATTATCAAGCACTAACTCGTCGAAAA
TGGTGGCCAACACAATGGAACGATTTACGGGACTGGCGTGTTTATTCTTTGTTGATGGTACTTTTGGTTGCTGCTCAGCC
TGACTTGGGAAATGCTTCCATTATTGTATTGACAGCCATTATTATGTTTTCTATCAGTGGCATTGGTTACCGATGGTTTT
CGGCTATCCTAGTCATGATTACCGGTCTATCCACGGTCTTTCTTGGGACTATTGCCGTTATTGGGGTAGAAAGAGTTGCT
AAGATTCCTGTTTTTGGCTATGTCGCTAAACGTTTTAGTGCCTTTTTTAATCCTTTCCATGACTTGACCGATTCAGGTCA
CCAATTAGCCAATTCTTACTATGCTATGAGTAATGGTGGGTGGTTTGGCCAAGGGTTAGGAAATTCCATTGAAAAGCGTG
GTTATTTGCCCGAAGCACAGACAGACTTTGTCTTTTCAGTTGTCATTGAAGAGTTAGGTCTAATAGGAGCAGGGTTTATT
TTGGCACTTGTTTTCTTCTTAATTTTACGTATTATGAATGTTGGTATTAAAGCAAAAAATCCTTTTAATGCCATGATGGC
TTTAGGAGTAGGCGGTATGATGCTCATGCAAGTCTTTGTTAATATTGGTGGTATCTCAGGGTTAATTCCATCTACTGGTG
TTACCTTCCCTTTTTTGTCTCAAGGTGGAAATAGCTTACTTGTCTTATCTGTTGCAGTGGGTTTTGTACTAAATATTGAT
GCTAGCGAAAAGCGAGATGATATATTTAAAGAAGCTGAATTATCTTATCGAAAGGACACTCGAAAAGAAAATAGTAAAGT
TGTAAATATCAAGCAATTTCAATAA

Upstream 100 bases:

>100_bases
GTGACTAATCAGAATTTTAAAGGTTAGCCCTTGGAGCTTCTTTTTTTGAGGATTCTTGACTTTTTCTTTTGTTTGATATA
GAAAGATGTTATAATGCTAA

Downstream 100 bases:

>100_bases
TATTCTAAAATCTCCTTTAAGGAGATTTTAGAATATAGACAATCCCAGTTTGATGCTCAAAAAACTTGAACTGCTCTGCT
GATTTCTTATTTTTGCGTGT

Product: cell division protein ftsW

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 434; Mature: 434

Protein sequence:

>434_residues
MIISRSRGKTMKIDKRHLLNYSILLPYLILSVIGLIMVYSTTSVSLIQAHANPFKSVINQGVFWIISLVAITFIYKLKLN
FLTNTRVLTVVMLGEAFLLIIARFFTTAIKGAHGWIVIGPVSFQPAEYLKIIMVWYLALTFAKIQKNISLYDYQALTRRK
WWPTQWNDLRDWRVYSLLMVLLVAAQPDLGNASIIVLTAIIMFSISGIGYRWFSAILVMITGLSTVFLGTIAVIGVERVA
KIPVFGYVAKRFSAFFNPFHDLTDSGHQLANSYYAMSNGGWFGQGLGNSIEKRGYLPEAQTDFVFSVVIEELGLIGAGFI
LALVFFLILRIMNVGIKAKNPFNAMMALGVGGMMLMQVFVNIGGISGLIPSTGVTFPFLSQGGNSLLVLSVAVGFVLNID
ASEKRDDIFKEAELSYRKDTRKENSKVVNIKQFQ

Sequences:

>Translated_434_residues
MIISRSRGKTMKIDKRHLLNYSILLPYLILSVIGLIMVYSTTSVSLIQAHANPFKSVINQGVFWIISLVAITFIYKLKLN
FLTNTRVLTVVMLGEAFLLIIARFFTTAIKGAHGWIVIGPVSFQPAEYLKIIMVWYLALTFAKIQKNISLYDYQALTRRK
WWPTQWNDLRDWRVYSLLMVLLVAAQPDLGNASIIVLTAIIMFSISGIGYRWFSAILVMITGLSTVFLGTIAVIGVERVA
KIPVFGYVAKRFSAFFNPFHDLTDSGHQLANSYYAMSNGGWFGQGLGNSIEKRGYLPEAQTDFVFSVVIEELGLIGAGFI
LALVFFLILRIMNVGIKAKNPFNAMMALGVGGMMLMQVFVNIGGISGLIPSTGVTFPFLSQGGNSLLVLSVAVGFVLNID
ASEKRDDIFKEAELSYRKDTRKENSKVVNIKQFQ
>Mature_434_residues
MIISRSRGKTMKIDKRHLLNYSILLPYLILSVIGLIMVYSTTSVSLIQAHANPFKSVINQGVFWIISLVAITFIYKLKLN
FLTNTRVLTVVMLGEAFLLIIARFFTTAIKGAHGWIVIGPVSFQPAEYLKIIMVWYLALTFAKIQKNISLYDYQALTRRK
WWPTQWNDLRDWRVYSLLMVLLVAAQPDLGNASIIVLTAIIMFSISGIGYRWFSAILVMITGLSTVFLGTIAVIGVERVA
KIPVFGYVAKRFSAFFNPFHDLTDSGHQLANSYYAMSNGGWFGQGLGNSIEKRGYLPEAQTDFVFSVVIEELGLIGAGFI
LALVFFLILRIMNVGIKAKNPFNAMMALGVGGMMLMQVFVNIGGISGLIPSTGVTFPFLSQGGNSLLVLSVAVGFVLNID
ASEKRDDIFKEAELSYRKDTRKENSKVVNIKQFQ

Specific function: This is a septum-peptidoglycan biosynthetic protein, involved in cell wall formation. Plays a role in the stabilization of the ftsZ ring during cell division [H]

COG id: COG0772

COG function: function code D; Bacterial cell division membrane protein

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ftsW/rodA/spoVE family [H]

Homologues:

Organism=Escherichia coli, GI1786277, Length=402, Percent_Identity=32.089552238806, Blast_Score=175, Evalue=5e-45,
Organism=Escherichia coli, GI1786853, Length=314, Percent_Identity=30.8917197452229, Blast_Score=114, Evalue=1e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001182
- InterPro:   IPR018365 [H]

Pfam domain/function: PF01098 FTSW_RODA_SPOVE [H]

EC number: NA

Molecular weight: Translated: 48382; Mature: 48382

Theoretical pI: Translated: 10.32; Mature: 10.32

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIISRSRGKTMKIDKRHLLNYSILLPYLILSVIGLIMVYSTTSVSLIQAHANPFKSVINQ
CCCCCCCCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCHHHHHHHHC
GVFWIISLVAITFIYKLKLNFLTNTRVLTVVMLGEAFLLIIARFFTTAIKGAHGWIVIGP
HHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEC
VSFQPAEYLKIIMVWYLALTFAKIQKNISLYDYQALTRRKWWPTQWNDLRDWRVYSLLMV
CCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHH
LLVAAQPDLGNASIIVLTAIIMFSISGIGYRWFSAILVMITGLSTVFLGTIAVIGVERVA
HHHHCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KIPVFGYVAKRFSAFFNPFHDLTDSGHQLANSYYAMSNGGWFGQGLGNSIEKRGYLPEAQ
HCCHHHHHHHHHHHHHCHHHHHCCCHHHHHHHHEEECCCCEECCCCCCHHHHCCCCCCCC
TDFVFSVVIEELGLIGAGFILALVFFLILRIMNVGIKAKNPFNAMMALGVGGMMLMQVFV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHCCHHHHHHHHHH
NIGGISGLIPSTGVTFPFLSQGGNSLLVLSVAVGFVLNIDASEKRDDIFKEAELSYRKDT
HHCCCCCCCCCCCCCCCHHHCCCCEEEEHEEHHHHHEECCCCCHHHHHHHHHHHHHHHHC
RKENSKVVNIKQFQ
CCCCCCEEEEECCC
>Mature Secondary Structure
MIISRSRGKTMKIDKRHLLNYSILLPYLILSVIGLIMVYSTTSVSLIQAHANPFKSVINQ
CCCCCCCCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCHHHHHHHHC
GVFWIISLVAITFIYKLKLNFLTNTRVLTVVMLGEAFLLIIARFFTTAIKGAHGWIVIGP
HHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEC
VSFQPAEYLKIIMVWYLALTFAKIQKNISLYDYQALTRRKWWPTQWNDLRDWRVYSLLMV
CCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHH
LLVAAQPDLGNASIIVLTAIIMFSISGIGYRWFSAILVMITGLSTVFLGTIAVIGVERVA
HHHHCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KIPVFGYVAKRFSAFFNPFHDLTDSGHQLANSYYAMSNGGWFGQGLGNSIEKRGYLPEAQ
HCCHHHHHHHHHHHHHCHHHHHCCCHHHHHHHHEEECCCCEECCCCCCHHHHCCCCCCCC
TDFVFSVVIEELGLIGAGFILALVFFLILRIMNVGIKAKNPFNAMMALGVGGMMLMQVFV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHCCHHHHHHHHHH
NIGGISGLIPSTGVTFPFLSQGGNSLLVLSVAVGFVLNIDASEKRDDIFKEAELSYRKDT
HHCCCCCCCCCCCCCCCHHHCCCCEEEEHEEHHHHHEECCCCCHHHHHHHHHHHHHHHHC
RKENSKVVNIKQFQ
CCCCCCEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11337471 [H]