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The map label for this gene is yidA [H]

Identifier: 94993889

GI number: 94993889

Start: 474492

End: 475316

Strand: Direct

Name: yidA [H]

Synonym: MGAS10750_Spy0493

Alternate gene names: 94993889

Gene position: 474492-475316 (Clockwise)

Preceding gene: 94993888

Following gene: 94993890

Centisome position: 24.49

GC content: 43.03

Gene sequence:

>825_bases
ATGAATATTAGAATTTTGGCGCTTGATTTAGACGGTACCCTCTACAACACTGAAAAAATTGTCACAGATGCCAATAAAAA
AGCCTTAGCAGCGGTTAGAGAAAAAGGGGTTAAGGTGGTTATTACCACAGGTCGCCCTCTAAAGGCCATCGGTAACTTGC
TAGAAGAGTTGGACTTGCTTGACCACGATGACTACAGTATTACCTTTAATGGGGGTTTGGTTCAGCGAAATACAGGGGAG
GTTTTGGATAAGAGCTCTCTCAGTTTTGACCAGGTTTGCCAGATTCAGCAAGCTTTAGAGGCGGTTGGCTTACCAACAGA
TATTATCAGTGGTGGGGATGTGTATAGCATTCCAAGTAAGGACGGTAGGCATTCGCAGTACCATCTAGCTAACCCACTGT
TGACCTTTATTGAGGTGACATCTGTAGCGGAACTACCAAAAGACATTACCTATAACAAAATTGTGACAGTCACCGATCCA
GACTTTTTGGATCAGCAGATTATAAAGCTATCCCCAAGCTTATTTGAGGATTTTGAAGCCTTTAAATCACGAGATATTAT
TTTTGAAATCATGCCAAAAGGCATTGATAAAGCTTTTGGATTAAACTTGCTTTGCCAGCACCTTGGCCTTGACGCTAGAC
ATGTCATGGCTATGGGAGACGAAGCTAACGACTTTGCGATGTTAGAATGGGCAGGACTTGGAGTAGCTATGGCTAATGGT
GTTTCAGGAGCTAAAGCCGTTGCCGATGCCGTGACCACCTTGACCAATGATGAGTCTGGAGTTGCAGAAGCTGTGAAGAC
ATTTATTTTAGAAGAGGAGAGTTAA

Upstream 100 bases:

>100_bases
GGAAAATGCAAGACCTGAAATCAAAGTGATTTCAGACCAAGTCATTGGCCACTGTAATGACGGAGCAGTACTAACGTATT
TAAAAGGACTAGTGTAACTC

Downstream 100 bases:

>100_bases
TGGGATTATTTGATCGTTTATTTGGGAAAAAAGAAACCCCGAAGGTAGCTGAGGAAAAGTTAGAAGAAAATCTTTTGACA
GAAACAACTCAGAAAGAGGA

Product: hydrolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 274; Mature: 274

Protein sequence:

>274_residues
MNIRILALDLDGTLYNTEKIVTDANKKALAAVREKGVKVVITTGRPLKAIGNLLEELDLLDHDDYSITFNGGLVQRNTGE
VLDKSSLSFDQVCQIQQALEAVGLPTDIISGGDVYSIPSKDGRHSQYHLANPLLTFIEVTSVAELPKDITYNKIVTVTDP
DFLDQQIIKLSPSLFEDFEAFKSRDIIFEIMPKGIDKAFGLNLLCQHLGLDARHVMAMGDEANDFAMLEWAGLGVAMANG
VSGAKAVADAVTTLTNDESGVAEAVKTFILEEES

Sequences:

>Translated_274_residues
MNIRILALDLDGTLYNTEKIVTDANKKALAAVREKGVKVVITTGRPLKAIGNLLEELDLLDHDDYSITFNGGLVQRNTGE
VLDKSSLSFDQVCQIQQALEAVGLPTDIISGGDVYSIPSKDGRHSQYHLANPLLTFIEVTSVAELPKDITYNKIVTVTDP
DFLDQQIIKLSPSLFEDFEAFKSRDIIFEIMPKGIDKAFGLNLLCQHLGLDARHVMAMGDEANDFAMLEWAGLGVAMANG
VSGAKAVADAVTTLTNDESGVAEAVKTFILEEES
>Mature_274_residues
MNIRILALDLDGTLYNTEKIVTDANKKALAAVREKGVKVVITTGRPLKAIGNLLEELDLLDHDDYSITFNGGLVQRNTGE
VLDKSSLSFDQVCQIQQALEAVGLPTDIISGGDVYSIPSKDGRHSQYHLANPLLTFIEVTSVAELPKDITYNKIVTVTDP
DFLDQQIIKLSPSLFEDFEAFKSRDIIFEIMPKGIDKAFGLNLLCQHLGLDARHVMAMGDEANDFAMLEWAGLGVAMANG
VSGAKAVADAVTTLTNDESGVAEAVKTFILEEES

Specific function: Catalyzes the dephosphorylation of the artificial chromogenic substrate p-nitrophenyl phosphate (pNPP) and of the natural substrates erythrose 4-phosphate and mannose 1-phosphate [H]

COG id: COG0561

COG function: function code R; Predicted hydrolases of the HAD superfamily

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HAD-like hydrolase superfamily. Cof family [H]

Homologues:

Organism=Escherichia coli, GI2367265, Length=274, Percent_Identity=34.3065693430657, Blast_Score=157, Evalue=8e-40,
Organism=Escherichia coli, GI1786982, Length=257, Percent_Identity=28.7937743190661, Blast_Score=73, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005834
- InterPro:   IPR023214
- InterPro:   IPR006379
- InterPro:   IPR000150 [H]

Pfam domain/function: PF00702 Hydrolase [H]

EC number: NA

Molecular weight: Translated: 29757; Mature: 29757

Theoretical pI: Translated: 4.30; Mature: 4.30

Prosite motif: PS01228 COF_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNIRILALDLDGTLYNTEKIVTDANKKALAAVREKGVKVVITTGRPLKAIGNLLEELDLL
CCEEEEEEECCCCEECCHHHEECCCHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHHCC
DHDDYSITFNGGLVQRNTGEVLDKSSLSFDQVCQIQQALEAVGLPTDIISGGDVYSIPSK
CCCCEEEEECCCEEECCCCHHHCCCCCCHHHHHHHHHHHHHHCCCHHHCCCCCEEECCCC
DGRHSQYHLANPLLTFIEVTSVAELPKDITYNKIVTVTDPDFLDQQIIKLSPSLFEDFEA
CCCCCCEEHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCHHHHHHHHHCHHHHHHHHH
FKSRDIIFEIMPKGIDKAFGLNLLCQHLGLDARHVMAMGDEANDFAMLEWAGLGVAMANG
HHCCCEEEEECCCCCHHHHHHHHHHHHHCCCHHHHEEECCCCCCEEEEEECCCCEEECCC
VSGAKAVADAVTTLTNDESGVAEAVKTFILEEES
CCHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCC
>Mature Secondary Structure
MNIRILALDLDGTLYNTEKIVTDANKKALAAVREKGVKVVITTGRPLKAIGNLLEELDLL
CCEEEEEEECCCCEECCHHHEECCCHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHHCC
DHDDYSITFNGGLVQRNTGEVLDKSSLSFDQVCQIQQALEAVGLPTDIISGGDVYSIPSK
CCCCEEEEECCCEEECCCCHHHCCCCCCHHHHHHHHHHHHHHCCCHHHCCCCCEEECCCC
DGRHSQYHLANPLLTFIEVTSVAELPKDITYNKIVTVTDPDFLDQQIIKLSPSLFEDFEA
CCCCCCEEHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCHHHHHHHHHCHHHHHHHHH
FKSRDIIFEIMPKGIDKAFGLNLLCQHLGLDARHVMAMGDEANDFAMLEWAGLGVAMANG
HHCCCEEEEECCCCCHHHHHHHHHHHHHCCCHHHHEEECCCCCCEEEEEECCCCEEECCC
VSGAKAVADAVTTLTNDESGVAEAVKTFILEEES
CCHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]