| Definition | Streptococcus pyogenes MGAS10750 chromosome, complete genome. |
|---|---|
| Accession | NC_008024 |
| Length | 1,937,111 |
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The map label for this gene is ftsK [H]
Identifier: 94993770
GI number: 94993770
Start: 376144
End: 378549
Strand: Direct
Name: ftsK [H]
Synonym: MGAS10750_Spy0374
Alternate gene names: 94993770
Gene position: 376144-378549 (Clockwise)
Preceding gene: 94993768
Following gene: 162139190
Centisome position: 19.42
GC content: 40.44
Gene sequence:
>2406_bases ATGGTTAAAAGAAATCAAAGAAGAAAAAGTGCGCCTAAGAAGCGTCTGACAAAAGCAGAAGTGGAAAAGCAACGTGCCAT TAAGAGGATGATTTTATCTGTTTTAATGGCTTTGTTGCTTATTTTTGCGATGCTTCGCTTGGGCGTCTTTGGCGTGACAA CTTATAATATGATTCGTTTTTTGGTGGGTAGTTTAGCCTATCCGTTTATGTTTGCCTGGTTAATTTACTTATTTTGTTTT AAATGGTTACGGCAAAAAGATGGAATGATTGCGGGAGTTGTTATTGCCTTTTTGGGATTGCTAGTTGAGTGGCACGCCTT CTTATTTGCGATGCCTAGGATGCTTGATCAAGATATTTTTCTAGGCACTGCGCGGCTAATTACAAGAGATTTACTAGCCC TGCGCGTGACTGAATTTGTTGGTGGAGGAATGCTTGGTGCATTACTTTATAAACCCATAGCCTTTTTATTTTCGAATATC GGCTCTTACTTTATTGGTTTTTTGTTTATCTTATTAGGATTATTTCTAATGACGCCTTGGGATATCTATGATGTGAGTCA CCTTGTGAAAGAGGCTGTTGATAAACTAGCAGTGGCTTATCAGGAAAATAAAGAAAAGCGGTTCATCAAACGAGAAGAGC ACCGCTTACAAGCTGAAAAAGAGGCTTTAGAGAAACAAGCACAAGAGGAAGAAAAACGTCTAGCAGAATTGACGGTTGAT CCTGAGACGGGAGAGATTGTTGAGGATAGTCAGTCTCAAGTCAGCTATGATTTGGCTGAGGATATGACAAAAGAGCCAGA GATTCTTGCTTATGATAGTCACCTCAAAGACGATGAGGCAAGCTTATTTGACCAAGAAGACTTGGCTTATGCTCATGAGG AAATTGGGGCTTATGACTCTTTATCTGCTTTAGCATCTTCTGAAGATGAGATGGATATGGATGAACCTGTTGAAGTTGAT TTCACACCAAAAACCCATCTTCTTTATAAACTTCCAACGATAGATTTATTTGCACCAGATAAGCCCAAAAACCAGTCCAA AGAGAAAAACTTAGTCCGCAAAAATATCAAGGTGCTTGAAGATACCTTCCAAAGTTTTGGGATTGATGTCAAGGTAGAAC GAGCAGAAATCGGGCCTTCCGTCACCAAATATGAAATTAAACCAGCTGTCGGGGTCCGAGTTAATCGTATTTCAAATCTT GCTGATGATTTGGCACTTGCTCTGGCTGCTAAAGATGTTCGTATTGAAGCACCAATTCCTGGAAAATCATTAATAGGTAT TGAAGTTCCTAACTCAGAAATTGCAACGGTTTCTTTCCGCGAACTTTGGGAACAATCTGATGCCAATCCTGAAAACCTTT TAGAAGTACCACTAGGTAAAGCTGTTAATGGCAACGCTCGCAGTTTTAACTTAGCTAGAATGCCGCATCTTTTGGTAGCT GGGTCAACTGGTTCAGGTAAATCTGTGGCAGTTAATGGCATTATTTCAAGTATTTTGATGAAGGCACGTCCAGATCAAGT TAAGTTTATGATGATTGACCCCAAAATGGTTGAATTATCTGTTTATAATGATATTCCACATTTATTAATCCCTGTTGTAA CCAATCCGCGTAAAGCCAGTAAGGCACTCCAAAAAGTGGTTGATGAGATGGAAAACCGCTACGAGTTATTTAGTAAAATT GGTGTGCGTAATATAGCAGGTTATAATACAAAGGTTGAAGAGTTTAATGCTTCTTCTGAGCAAAAACAAATACCGTTGCC TTTAATCGTTGTCATTGTAGATGAATTGGCTGACTTGATGATGGTTGCTAGTAAAGAAGTTGAAGATGCTATTATTCGTT TGGGGCAAAAAGCGCGTGCGGCAGGTATCCATATGATTCTTGCAACTCAACGTCCCTCTGTAGATGTTATTTCTGGTTTG ATTAAAGCAAATGTTCCTTCGCGTATGGCATTTGCTGTTTCAAGTGGTACTGATAGCCGTACGATCCTTGATGAAAATGG TGCTGAAAAGCTCTTGGGACGGGGTGATATGCTCTTTAAGCCGATTGATGAAAATCACCCTGTTCGCTTGCAAGGGTCTT TCATCTCAGATGATGATGTGGAGCGTATTGTCAACTTTATCAAAGACCAAGCTGAAGCGGATTATGATGACGCCTTTGAT CCTGGTGAAGTTAGCGACAATGATCCTGGTTTTTCTGGAAATGGCGGAGCTGCTGAAGGTGATCCTCTTTTTGAAGAAGC AAAAGCCTTGGTCTTAGAGACACAAAAAGCTAGTGCCTCAATGATTCAAAGGCGTTTGTCGGTTGGATTTAATCGTGCCA CGCGCTTGATGGATGAATTGGAAGAAGCAGGTGTTATCGGTCCAGCAGAAGGAACCAAACCTCGTAAGGTATTGCAGACA AACTAA
Upstream 100 bases:
>100_bases CTACGACTGTTATTATAGCACAAGATGCTATAGAAAAACTTAAAATACCTTGGTTTTTTAGAGCTATTTCCTAATAGTTA AAAAATGGTATAATAGTGTT
Downstream 100 bases:
>100_bases AAGAACCTGACGTCTCATAATGAGATGTCAGGTTCTTTTTTTGTGATGTCAGGCCAGTTGATGAGATGCCTATGCTAATG TAAAAATAAAGATAACTAGA
Product: cell division protein ftsK
Products: NA
Alternate protein names: NA
Number of amino acids: Translated: 801; Mature: 801
Protein sequence:
>801_residues MVKRNQRRKSAPKKRLTKAEVEKQRAIKRMILSVLMALLLIFAMLRLGVFGVTTYNMIRFLVGSLAYPFMFAWLIYLFCF KWLRQKDGMIAGVVIAFLGLLVEWHAFLFAMPRMLDQDIFLGTARLITRDLLALRVTEFVGGGMLGALLYKPIAFLFSNI GSYFIGFLFILLGLFLMTPWDIYDVSHLVKEAVDKLAVAYQENKEKRFIKREEHRLQAEKEALEKQAQEEEKRLAELTVD PETGEIVEDSQSQVSYDLAEDMTKEPEILAYDSHLKDDEASLFDQEDLAYAHEEIGAYDSLSALASSEDEMDMDEPVEVD FTPKTHLLYKLPTIDLFAPDKPKNQSKEKNLVRKNIKVLEDTFQSFGIDVKVERAEIGPSVTKYEIKPAVGVRVNRISNL ADDLALALAAKDVRIEAPIPGKSLIGIEVPNSEIATVSFRELWEQSDANPENLLEVPLGKAVNGNARSFNLARMPHLLVA GSTGSGKSVAVNGIISSILMKARPDQVKFMMIDPKMVELSVYNDIPHLLIPVVTNPRKASKALQKVVDEMENRYELFSKI GVRNIAGYNTKVEEFNASSEQKQIPLPLIVVIVDELADLMMVASKEVEDAIIRLGQKARAAGIHMILATQRPSVDVISGL IKANVPSRMAFAVSSGTDSRTILDENGAEKLLGRGDMLFKPIDENHPVRLQGSFISDDDVERIVNFIKDQAEADYDDAFD PGEVSDNDPGFSGNGGAAEGDPLFEEAKALVLETQKASASMIQRRLSVGFNRATRLMDELEEAGVIGPAEGTKPRKVLQT N
Sequences:
>Translated_801_residues MVKRNQRRKSAPKKRLTKAEVEKQRAIKRMILSVLMALLLIFAMLRLGVFGVTTYNMIRFLVGSLAYPFMFAWLIYLFCF KWLRQKDGMIAGVVIAFLGLLVEWHAFLFAMPRMLDQDIFLGTARLITRDLLALRVTEFVGGGMLGALLYKPIAFLFSNI GSYFIGFLFILLGLFLMTPWDIYDVSHLVKEAVDKLAVAYQENKEKRFIKREEHRLQAEKEALEKQAQEEEKRLAELTVD PETGEIVEDSQSQVSYDLAEDMTKEPEILAYDSHLKDDEASLFDQEDLAYAHEEIGAYDSLSALASSEDEMDMDEPVEVD FTPKTHLLYKLPTIDLFAPDKPKNQSKEKNLVRKNIKVLEDTFQSFGIDVKVERAEIGPSVTKYEIKPAVGVRVNRISNL ADDLALALAAKDVRIEAPIPGKSLIGIEVPNSEIATVSFRELWEQSDANPENLLEVPLGKAVNGNARSFNLARMPHLLVA GSTGSGKSVAVNGIISSILMKARPDQVKFMMIDPKMVELSVYNDIPHLLIPVVTNPRKASKALQKVVDEMENRYELFSKI GVRNIAGYNTKVEEFNASSEQKQIPLPLIVVIVDELADLMMVASKEVEDAIIRLGQKARAAGIHMILATQRPSVDVISGL IKANVPSRMAFAVSSGTDSRTILDENGAEKLLGRGDMLFKPIDENHPVRLQGSFISDDDVERIVNFIKDQAEADYDDAFD PGEVSDNDPGFSGNGGAAEGDPLFEEAKALVLETQKASASMIQRRLSVGFNRATRLMDELEEAGVIGPAEGTKPRKVLQT N >Mature_801_residues MVKRNQRRKSAPKKRLTKAEVEKQRAIKRMILSVLMALLLIFAMLRLGVFGVTTYNMIRFLVGSLAYPFMFAWLIYLFCF KWLRQKDGMIAGVVIAFLGLLVEWHAFLFAMPRMLDQDIFLGTARLITRDLLALRVTEFVGGGMLGALLYKPIAFLFSNI GSYFIGFLFILLGLFLMTPWDIYDVSHLVKEAVDKLAVAYQENKEKRFIKREEHRLQAEKEALEKQAQEEEKRLAELTVD PETGEIVEDSQSQVSYDLAEDMTKEPEILAYDSHLKDDEASLFDQEDLAYAHEEIGAYDSLSALASSEDEMDMDEPVEVD FTPKTHLLYKLPTIDLFAPDKPKNQSKEKNLVRKNIKVLEDTFQSFGIDVKVERAEIGPSVTKYEIKPAVGVRVNRISNL ADDLALALAAKDVRIEAPIPGKSLIGIEVPNSEIATVSFRELWEQSDANPENLLEVPLGKAVNGNARSFNLARMPHLLVA GSTGSGKSVAVNGIISSILMKARPDQVKFMMIDPKMVELSVYNDIPHLLIPVVTNPRKASKALQKVVDEMENRYELFSKI GVRNIAGYNTKVEEFNASSEQKQIPLPLIVVIVDELADLMMVASKEVEDAIIRLGQKARAAGIHMILATQRPSVDVISGL IKANVPSRMAFAVSSGTDSRTILDENGAEKLLGRGDMLFKPIDENHPVRLQGSFISDDDVERIVNFIKDQAEADYDDAFD PGEVSDNDPGFSGNGGAAEGDPLFEEAKALVLETQKASASMIQRRLSVGFNRATRLMDELEEAGVIGPAEGTKPRKVLQT N
Specific function: DNA motor protein, which is both required to move DNA out of the region of the septum during cell division and for the septum formation. Tracks DNA in an ATP-dependent manner by generating positive supercoils in front of it and negative supercoils behind
COG id: COG1674
COG function: function code D; DNA segregation ATPase FtsK/SpoIIIE and related proteins
Gene ontology:
Cell location: Cell membrane; Multi-pass membrane protein. Note=Located at the septum. The large C-terminal part of the protein is cytoplasmic (Potential) [H]
Metaboloic importance: Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Contains 1 FtsK domain [H]
Homologues:
Organism=Escherichia coli, GI1787117, Length=487, Percent_Identity=46.2012320328542, Blast_Score=402, Evalue=1e-113,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR003593 - InterPro: IPR018541 - InterPro: IPR002543 [H]
Pfam domain/function: PF09397 Ftsk_gamma; PF01580 FtsK_SpoIIIE [H]
EC number: NA
Molecular weight: Translated: 89263; Mature: 89263
Theoretical pI: Translated: 4.92; Mature: 4.92
Prosite motif: PS50901 FTSK
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.1 %Cys (Translated Protein) 3.4 %Met (Translated Protein) 3.5 %Cys+Met (Translated Protein) 0.1 %Cys (Mature Protein) 3.4 %Met (Mature Protein) 3.5 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MVKRNQRRKSAPKKRLTKAEVEKQRAIKRMILSVLMALLLIFAMLRLGVFGVTTYNMIRF CCCCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH LVGSLAYPFMFAWLIYLFCFKWLRQKDGMIAGVVIAFLGLLVEWHAFLFAMPRMLDQDIF HHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH LGTARLITRDLLALRVTEFVGGGMLGALLYKPIAFLFSNIGSYFIGFLFILLGLFLMTPW HHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC DIYDVSHLVKEAVDKLAVAYQENKEKRFIKREEHRLQAEKEALEKQAQEEEKRLAELTVD CHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECC PETGEIVEDSQSQVSYDLAEDMTKEPEILAYDSHLKDDEASLFDQEDLAYAHEEIGAYDS CCCCCHHCCCHHHHHHHHHHHCCCCCCEEEECCCCCCCHHHHCCHHHHHHHHHHHCCHHH LSALASSEDEMDMDEPVEVDFTPKTHLLYKLPTIDLFAPDKPKNQSKEKNLVRKNIKVLE HHHHHCCCCCCCCCCCCEEECCCCCEEEEECCEEEEECCCCCCCCHHHHHHHHHHHHHHH DTFQSFGIDVKVERAEIGPSVTKYEIKPAVGVRVNRISNLADDLALALAAKDVRIEAPIP HHHHHCCCCEEEEHHHCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHCCCEEECCCC GKSLIGIEVPNSEIATVSFRELWEQSDANPENLLEVPLGKAVNGNARSFNLARMPHLLVA CCCEEEEECCCCCEEEEHHHHHHHHCCCCHHHHHHCCCCCCCCCCCCCEEHHHCCEEEEE GSTGSGKSVAVNGIISSILMKARPDQVKFMMIDPKMVELSVYNDIPHLLIPVVTNPRKAS CCCCCCCCEEHHHHHHHHHHHCCCCCEEEEEECCEEEEEEECCCCCCCEEECCCCCHHHH KALQKVVDEMENRYELFSKIGVRNIAGYNTKVEEFNASSEQKQIPLPLIVVIVDELADLM HHHHHHHHHHHHHHHHHHHHCHHHCCCCCCCHHHCCCCCCCCCCCCHHHHHHHHHHHHHH MVASKEVEDAIIRLGQKARAAGIHMILATQRPSVDVISGLIKANVPSRMAFAVSSGTDSR HHHHHHHHHHHHHHCCHHHHCCEEEEEECCCCCHHHHHHHHHCCCCCCEEEEEECCCCCC TILDENGAEKLLGRGDMLFKPIDENHPVRLQGSFISDDDVERIVNFIKDQAEADYDDAFD EEECCCCHHHHHCCCCCEEECCCCCCCEEEECCCCCCHHHHHHHHHHHHHHCCCCCCCCC PGEVSDNDPGFSGNGGAAEGDPLFEEAKALVLETQKASASMIQRRLSVGFNRATRLMDEL CCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHH EEAGVIGPAEGTKPRKVLQTN HHCCCCCCCCCCCCCHHCCCC >Mature Secondary Structure MVKRNQRRKSAPKKRLTKAEVEKQRAIKRMILSVLMALLLIFAMLRLGVFGVTTYNMIRF CCCCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH LVGSLAYPFMFAWLIYLFCFKWLRQKDGMIAGVVIAFLGLLVEWHAFLFAMPRMLDQDIF HHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH LGTARLITRDLLALRVTEFVGGGMLGALLYKPIAFLFSNIGSYFIGFLFILLGLFLMTPW HHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC DIYDVSHLVKEAVDKLAVAYQENKEKRFIKREEHRLQAEKEALEKQAQEEEKRLAELTVD CHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECC PETGEIVEDSQSQVSYDLAEDMTKEPEILAYDSHLKDDEASLFDQEDLAYAHEEIGAYDS CCCCCHHCCCHHHHHHHHHHHCCCCCCEEEECCCCCCCHHHHCCHHHHHHHHHHHCCHHH LSALASSEDEMDMDEPVEVDFTPKTHLLYKLPTIDLFAPDKPKNQSKEKNLVRKNIKVLE HHHHHCCCCCCCCCCCCEEECCCCCEEEEECCEEEEECCCCCCCCHHHHHHHHHHHHHHH DTFQSFGIDVKVERAEIGPSVTKYEIKPAVGVRVNRISNLADDLALALAAKDVRIEAPIP HHHHHCCCCEEEEHHHCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHCCCEEECCCC GKSLIGIEVPNSEIATVSFRELWEQSDANPENLLEVPLGKAVNGNARSFNLARMPHLLVA CCCEEEEECCCCCEEEEHHHHHHHHCCCCHHHHHHCCCCCCCCCCCCCEEHHHCCEEEEE GSTGSGKSVAVNGIISSILMKARPDQVKFMMIDPKMVELSVYNDIPHLLIPVVTNPRKAS CCCCCCCCEEHHHHHHHHHHHCCCCCEEEEEECCEEEEEEECCCCCCCEEECCCCCHHHH KALQKVVDEMENRYELFSKIGVRNIAGYNTKVEEFNASSEQKQIPLPLIVVIVDELADLM HHHHHHHHHHHHHHHHHHHHCHHHCCCCCCCHHHCCCCCCCCCCCCHHHHHHHHHHHHHH MVASKEVEDAIIRLGQKARAAGIHMILATQRPSVDVISGLIKANVPSRMAFAVSSGTDSR HHHHHHHHHHHHHHCCHHHHCCEEEEEECCCCCHHHHHHHHHCCCCCCEEEEEECCCCCC TILDENGAEKLLGRGDMLFKPIDENHPVRLQGSFISDDDVERIVNFIKDQAEADYDDAFD EEECCCCHHHHHCCCCCEEECCCCCCCEEEECCCCCCHHHHHHHHHHHHHHCCCCCCCCC PGEVSDNDPGFSGNGGAAEGDPLFEEAKALVLETQKASASMIQRRLSVGFNRATRLMDEL CCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHH EEAGVIGPAEGTKPRKVLQTN HHCCCCCCCCCCCCCHHCCCC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 6.0
TargetDB status: NA
Availability: NA
References: 11296296 [H]