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The map label for this gene is mtsA [H]

Identifier: 94993766

GI number: 94993766

Start: 372394

End: 373329

Strand: Direct

Name: mtsA [H]

Synonym: MGAS10750_Spy0370

Alternate gene names: 94993766

Gene position: 372394-373329 (Clockwise)

Preceding gene: 94993764

Following gene: 94993767

Centisome position: 19.22

GC content: 35.58

Gene sequence:

>936_bases
ATGATGGGAAAGAGAATGAGCCTCATTTTGGGTGCTTTTTTATCTGTTTTTCTTTTAGTAGCTTGTTCGTCAACTGGCAC
TAAAACTGCTAAGAGTGATAAATTAAAAGTCGTGGCAACCAATTCAATTATTGCCGACATGACAAAAGCTATTGCTGGTG
ATAAAATCGATCTGCACAGCATTGTGCCAATCGGTCAAGACCCTCATGAGTACGAACCATTACCAGAAGATGTTGAAAAA
ACAAGTAATGCTGATGTGATTTTCTATAATGGTATCAATCTAGAAGATGGTGGGCAAGCTTGGTTCACTAAACTAGTGAA
AAATGCTCAAAAAACGAAAAACAAAGATTACTTTGCCGTGTCTGATGGCATTGATGTGATTTACTTGGAAGGTGCAAGCG
AAAAAGGAAAAGAAGATCCACATGCTTGGTTAAATCTCGAAAACGGAATCATTTATTCAAAAAACATTGCCAAACAATTG
ATTGCAAAGGATCCTAAAAACAAAGAAACTTATGAAAAGAACCTAAAAGCTTATGTGGCTAAATTGGAAAAACTAGACAA
AGAAGCTAAATCAAAATTTGATGCTATTGCAGAAAATAAAAAATTGATTGTGACTAGTGAAGGCTGCTTCAAGTACTTTT
CAAAAGCTTACGGTGTCCCATCTGCTTATATCTGGGAAATTAACACCGAAGAAGAAGGAACACCAGATCAAATTTCATCA
TTGATTGAAAAACTAAAAGTCATCAAGCCATCTGCGCTTTTTGTAGAGTCAAGTGTCGATAGACGCCCTATGGAAACTGT
CTCTAAAGATAGTGGTATTCCTATTTATTCTGAGATCTTTACAGATTCAATTGCTAAAAAAGGTAAACCTGGCGATAGTT
ATTATGCTATGATGAAATGGAACCTTGACAAAATTTCTGAAGGTCTAGCAAAATAA

Upstream 100 bases:

>100_bases
AATTTTTAGGAAAAAGCTTGACAAAAAGCCTAAAAGAGGATATCCTTATAGCATAATTAACTAAACTTAATTAAATAAAT
AATATATCCTAAGGAGAGAA

Downstream 100 bases:

>100_bases
GATAACAATAAAGCACAGCGATTTTAGTGTTGTGCTTTGTTTTATTTATGTAAAGGAGACAAAATGATTACAACTAACAA
TCTTTGTGTGACCTACGATG

Product: Manganese-binding protein

Products: Zn (II) [Cytoplasm]; ADP; phosphate [C]

Alternate protein names: NA

Number of amino acids: Translated: 311; Mature: 311

Protein sequence:

>311_residues
MMGKRMSLILGAFLSVFLLVACSSTGTKTAKSDKLKVVATNSIIADMTKAIAGDKIDLHSIVPIGQDPHEYEPLPEDVEK
TSNADVIFYNGINLEDGGQAWFTKLVKNAQKTKNKDYFAVSDGIDVIYLEGASEKGKEDPHAWLNLENGIIYSKNIAKQL
IAKDPKNKETYEKNLKAYVAKLEKLDKEAKSKFDAIAENKKLIVTSEGCFKYFSKAYGVPSAYIWEINTEEEGTPDQISS
LIEKLKVIKPSALFVESSVDRRPMETVSKDSGIPIYSEIFTDSIAKKGKPGDSYYAMMKWNLDKISEGLAK

Sequences:

>Translated_311_residues
MMGKRMSLILGAFLSVFLLVACSSTGTKTAKSDKLKVVATNSIIADMTKAIAGDKIDLHSIVPIGQDPHEYEPLPEDVEK
TSNADVIFYNGINLEDGGQAWFTKLVKNAQKTKNKDYFAVSDGIDVIYLEGASEKGKEDPHAWLNLENGIIYSKNIAKQL
IAKDPKNKETYEKNLKAYVAKLEKLDKEAKSKFDAIAENKKLIVTSEGCFKYFSKAYGVPSAYIWEINTEEEGTPDQISS
LIEKLKVIKPSALFVESSVDRRPMETVSKDSGIPIYSEIFTDSIAKKGKPGDSYYAMMKWNLDKISEGLAK
>Mature_311_residues
MMGKRMSLILGAFLSVFLLVACSSTGTKTAKSDKLKVVATNSIIADMTKAIAGDKIDLHSIVPIGQDPHEYEPLPEDVEK
TSNADVIFYNGINLEDGGQAWFTKLVKNAQKTKNKDYFAVSDGIDVIYLEGASEKGKEDPHAWLNLENGIIYSKNIAKQL
IAKDPKNKETYEKNLKAYVAKLEKLDKEAKSKFDAIAENKKLIVTSEGCFKYFSKAYGVPSAYIWEINTEEEGTPDQISS
LIEKLKVIKPSALFVESSVDRRPMETVSKDSGIPIYSEIFTDSIAKKGKPGDSYYAMMKWNLDKISEGLAK

Specific function: Part of an ATP-driven transport system for a metal; this protein has affinity for Zn(2+), Fe(3+) and Cu(2+) [H]

COG id: COG0803

COG function: function code P; ABC-type metal ion transport system, periplasmic component/surface adhesin

Gene ontology:

Cell location: Cell membrane; Lipid-anchor [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial solute-binding protein 9 family. Lipoprotein receptor antigen (Lrai) subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006127
- InterPro:   IPR006129
- InterPro:   IPR006128 [H]

Pfam domain/function: PF01297 SBP_bac_9 [H]

EC number: NA

Molecular weight: Translated: 34490; Mature: 34490

Theoretical pI: Translated: 6.81; Mature: 6.81

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMGKRMSLILGAFLSVFLLVACSSTGTKTAKSDKLKVVATNSIIADMTKAIAGDKIDLHS
CCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEECCHHHHHHHHHHCCCCCCHHE
IVPIGQDPHEYEPLPEDVEKTSNADVIFYNGINLEDGGQAWFTKLVKNAQKTKNKDYFAV
ECCCCCCCCCCCCCCHHHHHCCCCCEEEECCCCCCCCCHHHHHHHHHHHHHHCCCCEEEE
SDGIDVIYLEGASEKGKEDPHAWLNLENGIIYSKNIAKQLIAKDPKNKETYEKNLKAYVA
ECCCEEEEEECCCCCCCCCCCCEEEECCCEEECHHHHHHHHHCCCCCHHHHHHHHHHHHH
KLEKLDKEAKSKFDAIAENKKLIVTSEGCFKYFSKAYGVPSAYIWEINTEEEGTPDQISS
HHHHHHHHHHHHHHHHHCCCEEEEECHHHHHHHHHHHCCCCEEEEEECCCCCCCHHHHHH
LIEKLKVIKPSALFVESSVDRRPMETVSKDSGIPIYSEIFTDSIAKKGKPGDSYYAMMKW
HHHHHHHCCCCCEEEECCCCCCHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCCEEEEEEE
NLDKISEGLAK
CHHHHHHHHCC
>Mature Secondary Structure
MMGKRMSLILGAFLSVFLLVACSSTGTKTAKSDKLKVVATNSIIADMTKAIAGDKIDLHS
CCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEECCHHHHHHHHHHCCCCCCHHE
IVPIGQDPHEYEPLPEDVEKTSNADVIFYNGINLEDGGQAWFTKLVKNAQKTKNKDYFAV
ECCCCCCCCCCCCCCHHHHHCCCCCEEEECCCCCCCCCHHHHHHHHHHHHHHCCCCEEEE
SDGIDVIYLEGASEKGKEDPHAWLNLENGIIYSKNIAKQLIAKDPKNKETYEKNLKAYVA
ECCCEEEEEECCCCCCCCCCCCEEEECCCEEECHHHHHHHHHCCCCCHHHHHHHHHHHHH
KLEKLDKEAKSKFDAIAENKKLIVTSEGCFKYFSKAYGVPSAYIWEINTEEEGTPDQISS
HHHHHHHHHHHHHHHHHCCCEEEEECHHHHHHHHHHHCCCCEEEEEECCCCCCCHHHHHH
LIEKLKVIKPSALFVESSVDRRPMETVSKDSGIPIYSEIFTDSIAKKGKPGDSYYAMMKW
HHHHHHHCCCCCEEEECCCCCCHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCCEEEEEEE
NLDKISEGLAK
CHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Zn (II) [Periplasm]; H2O; ATP [C]

Specific reaction: Zn (II) [Periplasm] + H2O + ATP = Zn (II) [Cytoplasm] + ADP + phosphate [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 10564500; 11296296 [H]