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The map label for this gene is sstT [H]

Identifier: 94993666

GI number: 94993666

Start: 284828

End: 286042

Strand: Direct

Name: sstT [H]

Synonym: MGAS10750_Spy0270

Alternate gene names: 94993666

Gene position: 284828-286042 (Clockwise)

Preceding gene: 94993664

Following gene: 94993670

Centisome position: 14.7

GC content: 37.7

Gene sequence:

>1215_bases
ATGAAAAAAATATATGATTTATGGGTTAGGGTTAGTCTAATCAAAAAAATAGGTATCGGTGTTGTAATAGGAGTCATGTT
GGGCATTTTGGCTCCTGATCTTACAGGTTTTAGTATTTTAGGAAAGTTATTTGTTGGTGGTTTAAAGGCTATCGCACCTT
TGCTTGTATTTGCTTTGGTTTCCCAAGCCATCTCCCATCAGAAAAAAGGGAGACAGACTAATATGACATTAATCATTTTT
CTGTATTTATTTGGTACCTTTGCGTCAGCTTTAGTAGCAGTACTGACAGCTTATCTATTCCCTTTGACGTTAGTGTTAAA
TACACCTGTAAATACAGAATTATCACCACCTCAAGGTGTTGCTGAAGTTTTTCAGTCACTTCTATTAAAATTAGTGGATA
ATCCGATCAATGCTTTAGCTACTGCCAATTATATTGGTGTGCTATCATGGGCAATTATTTTTGGACTAGCATTAAAGGCT
GCAAGTCAAGAAACAAAGCATCTTATAAAAACAGCGGCAGAAGTTACTTCACAAATAGTTGTTTGGATCATCAATCTGGC
ACCTATTGGGATTATGAGTCTGGTGTTCACTACGATTTCTGAAAACGGTGTTGGAATCTTATCTGATTATGCTTTTTTGA
TACTAGTTTTAGTAGGAACAATGGTTTTTGTCGCCTTAGTGGTTAATCCACTTATTGCGGTTTTGATTACACGACAAAAT
CCTTATCCCCTTGTCTTAAGATGTTTACGTGAGTCAGGTCTTACAGCATTTTTCACACGAAGTTCTGCAGCCAATATTCC
AGTCAATATGCAGTTATGCCAAAAAATTGGATTGAGTAAAGATACTTATTCAGTGTCAATTCCACTTGGAGCAACTATTA
ATATGGGTGGGGCAGCAATTACCATCAATGTCCTAACGCTTGCTGCTGTACACACTTTTGGTATTCCTATTGATTTTCTA
ACAGCCCTCTTACTTAGCGTTGTTGCTGCTGTCTCTGCTTGTGGTGCTTCTGGTGTTGCTGGGGGATCGTTGTTACTTAT
TCCTGTAGCATGTAGTTTGTTTGGCATTTCAAATGATCTTGCGATGCAGGTGGTTGGTGTTGGTTTTATTGTTGGTGTTA
TCCAGGATTCTTGTGAGACAGCCTTAAATTCGTCAACCGATGTTCTTTTTACAGCTATTGCTGAAAATGCTTTTTGGAAA
CGTAAAAAAGCCTAG

Upstream 100 bases:

>100_bases
TAGCACAAAAAATGGTTAAGATATGTAGCTCATTCGATTTGACGAATAGATAGAATTATATTATTATAAAAAACATGTAA
CTTTAGTAAGGATGTAACGT

Downstream 100 bases:

>100_bases
CTAGGTTTAACATAATAAAAAACATCCTTGGAAAACGCCAAGGATGTTTTTTTATTATTTAAGATAGCCAAGATAATCAA
ATTTTTCAAAGGTGTGGTCA

Product: serine/threonine transporter SstT

Products: NA

Alternate protein names: Na(+)/serine-threonine symporter [H]

Number of amino acids: Translated: 404; Mature: 404

Protein sequence:

>404_residues
MKKIYDLWVRVSLIKKIGIGVVIGVMLGILAPDLTGFSILGKLFVGGLKAIAPLLVFALVSQAISHQKKGRQTNMTLIIF
LYLFGTFASALVAVLTAYLFPLTLVLNTPVNTELSPPQGVAEVFQSLLLKLVDNPINALATANYIGVLSWAIIFGLALKA
ASQETKHLIKTAAEVTSQIVVWIINLAPIGIMSLVFTTISENGVGILSDYAFLILVLVGTMVFVALVVNPLIAVLITRQN
PYPLVLRCLRESGLTAFFTRSSAANIPVNMQLCQKIGLSKDTYSVSIPLGATINMGGAAITINVLTLAAVHTFGIPIDFL
TALLLSVVAAVSACGASGVAGGSLLLIPVACSLFGISNDLAMQVVGVGFIVGVIQDSCETALNSSTDVLFTAIAENAFWK
RKKA

Sequences:

>Translated_404_residues
MKKIYDLWVRVSLIKKIGIGVVIGVMLGILAPDLTGFSILGKLFVGGLKAIAPLLVFALVSQAISHQKKGRQTNMTLIIF
LYLFGTFASALVAVLTAYLFPLTLVLNTPVNTELSPPQGVAEVFQSLLLKLVDNPINALATANYIGVLSWAIIFGLALKA
ASQETKHLIKTAAEVTSQIVVWIINLAPIGIMSLVFTTISENGVGILSDYAFLILVLVGTMVFVALVVNPLIAVLITRQN
PYPLVLRCLRESGLTAFFTRSSAANIPVNMQLCQKIGLSKDTYSVSIPLGATINMGGAAITINVLTLAAVHTFGIPIDFL
TALLLSVVAAVSACGASGVAGGSLLLIPVACSLFGISNDLAMQVVGVGFIVGVIQDSCETALNSSTDVLFTAIAENAFWK
RKKA
>Mature_404_residues
MKKIYDLWVRVSLIKKIGIGVVIGVMLGILAPDLTGFSILGKLFVGGLKAIAPLLVFALVSQAISHQKKGRQTNMTLIIF
LYLFGTFASALVAVLTAYLFPLTLVLNTPVNTELSPPQGVAEVFQSLLLKLVDNPINALATANYIGVLSWAIIFGLALKA
ASQETKHLIKTAAEVTSQIVVWIINLAPIGIMSLVFTTISENGVGILSDYAFLILVLVGTMVFVALVVNPLIAVLITRQN
PYPLVLRCLRESGLTAFFTRSSAANIPVNMQLCQKIGLSKDTYSVSIPLGATINMGGAAITINVLTLAAVHTFGIPIDFL
TALLLSVVAAVSACGASGVAGGSLLLIPVACSLFGISNDLAMQVVGVGFIVGVIQDSCETALNSSTDVLFTAIAENAFWK
RKKA

Specific function: Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system) [H]

COG id: COG3633

COG function: function code E; Na+/serine symporter

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sodium:dicarboxylate (SDF) symporter (TC 2.A.23) family [H]

Homologues:

Organism=Homo sapiens, GI223468564, Length=261, Percent_Identity=31.8007662835249, Blast_Score=96, Evalue=9e-20,
Organism=Homo sapiens, GI223468566, Length=261, Percent_Identity=31.8007662835249, Blast_Score=95, Evalue=1e-19,
Organism=Homo sapiens, GI5032093, Length=261, Percent_Identity=31.8007662835249, Blast_Score=92, Evalue=1e-18,
Organism=Homo sapiens, GI21314632, Length=274, Percent_Identity=30.6569343065693, Blast_Score=85, Evalue=9e-17,
Organism=Homo sapiens, GI169790839, Length=263, Percent_Identity=26.2357414448669, Blast_Score=77, Evalue=3e-14,
Organism=Homo sapiens, GI4827012, Length=268, Percent_Identity=25, Blast_Score=70, Evalue=3e-12,
Organism=Escherichia coli, GI1789473, Length=370, Percent_Identity=60, Blast_Score=428, Evalue=1e-121,
Organism=Escherichia coli, GI1789947, Length=248, Percent_Identity=29.8387096774194, Blast_Score=73, Evalue=3e-14,
Organism=Escherichia coli, GI1790514, Length=309, Percent_Identity=24.5954692556634, Blast_Score=71, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI71996953, Length=290, Percent_Identity=24.4827586206897, Blast_Score=79, Evalue=5e-15,
Organism=Caenorhabditis elegans, GI17537407, Length=270, Percent_Identity=25.5555555555556, Blast_Score=76, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI71983106, Length=285, Percent_Identity=25.9649122807018, Blast_Score=73, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI71983099, Length=271, Percent_Identity=26.5682656826568, Blast_Score=72, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI193206505, Length=267, Percent_Identity=24.7191011235955, Blast_Score=72, Evalue=5e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001991
- InterPro:   IPR023025 [H]

Pfam domain/function: PF00375 SDF [H]

EC number: NA

Molecular weight: Translated: 42617; Mature: 42617

Theoretical pI: Translated: 9.38; Mature: 9.38

Prosite motif: PS00099 THIOLASE_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure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HHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11296296 [H]