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The map label for this gene is metI [H]

Identifier: 94993664

GI number: 94993664

Start: 282479

End: 283171

Strand: Direct

Name: metI [H]

Synonym: MGAS10750_Spy0268

Alternate gene names: 94993664

Gene position: 282479-283171 (Clockwise)

Preceding gene: 94993663

Following gene: 94993666

Centisome position: 14.58

GC content: 37.52

Gene sequence:

>693_bases
ATGTCACAGTTAATTCAAACTTATTTGCCAAATGTTTATGAACTCGGATGGTCTGGAGATGCTGGTTGGGGCTTAGCGAT
TTGGAATACTTTATACATGACCATTGTGCCTTTTATTGTTGGGGGTGCTATTGGTCTCTTATTAGGCTTGTTATTAGTTT
TAACAGGACCGGACGGTGTTATTGAAAACAAAACGATTTGTTGGGTCATTGATAAAGTTACCTCTATTTTTAGAGCCATT
CCTTTTGTTATTTTGATTGCTATTTTAGCTAGCTTTACCTATTTGCTTTTAAGAACAACTTTAGGAGCAACAGCGGCCTT
GGTACCTTTAACCTTTGCGACTTTTCCTTTTTATGCCCGTCAGGTCCAAGTTGTTTTTTCAGAATTAGACAAGGGTGTTA
TTGAAGCAGCGCAAGCTTCAGGTGCTACTTTCTGGGATATTGTCAAAGTGTATCTCAGTGAAGGTTTACCAGATCTTATT
CGTGTTTCTACAGTCACCTTAATTTCTTTAGTTGGGGAAACTGCCATGGCAGGAGCTATCGGTGCTGGAGGATTAGGAAA
TGTAGCGATTTCTTATGGTTATAATCGTTTTAACAATGATGTGACTTGGGTAGCGACTATTATTATTCTTTTAATTATTT
TTGCTATCCAATTTATTGGTGATAGCTTGACCAGACGGTTTAGTCATAAATAA

Upstream 100 bases:

>100_bases
GATTGTTGTCTTGGAAGGGCAAGCTGAAAATATTCTTGCGGCTGAGAAAGCCTTGCATGAAGCTGGTGTTGATGTTAGTA
TTTTAAAGAGAGGAGCCTAG

Downstream 100 bases:

>100_bases
ACGAAACAACACCCTAAGTAAAAACTTAGGGTGTTGTTGTTTAGATGATGTCATTAGCTTTTCTTCGTTTTACTTAGTAT
AAGCCCTATTAAAAAACCAA

Product: ABC transporter permease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 230; Mature: 229

Protein sequence:

>230_residues
MSQLIQTYLPNVYELGWSGDAGWGLAIWNTLYMTIVPFIVGGAIGLLLGLLLVLTGPDGVIENKTICWVIDKVTSIFRAI
PFVILIAILASFTYLLLRTTLGATAALVPLTFATFPFYARQVQVVFSELDKGVIEAAQASGATFWDIVKVYLSEGLPDLI
RVSTVTLISLVGETAMAGAIGAGGLGNVAISYGYNRFNNDVTWVATIIILLIIFAIQFIGDSLTRRFSHK

Sequences:

>Translated_230_residues
MSQLIQTYLPNVYELGWSGDAGWGLAIWNTLYMTIVPFIVGGAIGLLLGLLLVLTGPDGVIENKTICWVIDKVTSIFRAI
PFVILIAILASFTYLLLRTTLGATAALVPLTFATFPFYARQVQVVFSELDKGVIEAAQASGATFWDIVKVYLSEGLPDLI
RVSTVTLISLVGETAMAGAIGAGGLGNVAISYGYNRFNNDVTWVATIIILLIIFAIQFIGDSLTRRFSHK
>Mature_229_residues
SQLIQTYLPNVYELGWSGDAGWGLAIWNTLYMTIVPFIVGGAIGLLLGLLLVLTGPDGVIENKTICWVIDKVTSIFRAIP
FVILIAILASFTYLLLRTTLGATAALVPLTFATFPFYARQVQVVFSELDKGVIEAAQASGATFWDIVKVYLSEGLPDLIR
VSTVTLISLVGETAMAGAIGAGGLGNVAISYGYNRFNNDVTWVATIIILLIIFAIQFIGDSLTRRFSHK

Specific function: Part of the ABC transporter complex metNIQ involved in methionine import. Responsible for the translocation of the substrate across the membrane (Probable). It has also been shown to be involved in methionine sulfoxide transport [H]

COG id: COG2011

COG function: function code P; ABC-type metal ion transport system, permease component

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1786397, Length=205, Percent_Identity=42.4390243902439, Blast_Score=125, Evalue=3e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 24869; Mature: 24737

Theoretical pI: Translated: 5.10; Mature: 5.10

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQLIQTYLPNVYELGWSGDAGWGLAIWNTLYMTIVPFIVGGAIGLLLGLLLVLTGPDGV
CHHHHHHHCCHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
IENKTICWVIDKVTSIFRAIPFVILIAILASFTYLLLRTTLGATAALVPLTFATFPFYAR
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QVQVVFSELDKGVIEAAQASGATFWDIVKVYLSEGLPDLIRVSTVTLISLVGETAMAGAI
HHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCC
GAGGLGNVAISYGYNRFNNDVTWVATIIILLIIFAIQFIGDSLTRRFSHK
CCCCCCCHHHHHCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SQLIQTYLPNVYELGWSGDAGWGLAIWNTLYMTIVPFIVGGAIGLLLGLLLVLTGPDGV
HHHHHHHCCHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
IENKTICWVIDKVTSIFRAIPFVILIAILASFTYLLLRTTLGATAALVPLTFATFPFYAR
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QVQVVFSELDKGVIEAAQASGATFWDIVKVYLSEGLPDLIRVSTVTLISLVGETAMAGAI
HHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCC
GAGGLGNVAISYGYNRFNNDVTWVATIIILLIIFAIQFIGDSLTRRFSHK
CCCCCCCHHHHHCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]