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The map label for this gene is pgi [H]

Identifier: 94993575

GI number: 94993575

Start: 192172

End: 193530

Strand: Direct

Name: pgi [H]

Synonym: MGAS10750_Spy0179

Alternate gene names: 94993575

Gene position: 192172-193530 (Clockwise)

Preceding gene: 94993574

Following gene: 94993578

Centisome position: 9.92

GC content: 41.57

Gene sequence:

>1359_bases
GTGAAACTCATGTCACATATTACATTTGATTATTCAAAAGTCCTCGAGTCATTTGCGGGACAACATGAAATTGATTTTTT
ACAAGGCCAAGTCACAGAGGCCGACAAGTTATTGCGTGAAGGAACTGGACCAGGTTCAGATTTCTTGGGCTGGCTTGATC
TTCCAGAAAACTATGATAAAGATGAATTTGCACGTATCTTGACTGCTGCTGAAAAAATTAAGTCAGACAGCGAAGTTCTT
GTGGTGATCGGTATTGGTGGGTCATACCTTGGTGCCAAAGCTGCTATCGATTTCTTAAACCATCACTTTGCTAACTTGCA
AACTGCCAAAGAGCGCAAAGCGCCACAAATTCTTTACGCTGGAAACTCTATTTCATCAACTTACTTAGCAGACCTTGTAG
AGTACGTTCAAGACAAAGAGTTCTCAGTAAACGTGATTTCTAAATCAGGAACAACTACTGAGCCAGCGATTGCTTTCCGT
GTCTTCAAAGAACTTTTGGTTAAAAAATATGGCCAAGAAGAAGCTAACAAGCGTATTTACGCTACAACAGACAAAGTGAA
AGGTGCTGTTAAGGTAGAAGCTGACGCTAACAACTGGGAAACATTTGTGGTGCCAGACAACGTTGGTGGTCGTTTCTCAG
TCTTGACTGCTGTTGGTTTGCTTCCAATTGCTGCATCAGGTGCAGATATCACAGCTCTTATGGAAGGTGCAAATGCAGCG
CGTAAAGACCTTTCTTCAGACAAAATCTCTGAAAACATTGCTTACCAATACGCTGCTGTTCGTAATGTGCTTTACCGTAA
AGGCTACATCACTGAAATCTTGGCTAACTACGAGCCATCTCTTCAATACTTTGGCGAATGGTGGAAACAATTAGCCGGTG
AATCAGAAGGAAAAGACCAAAAAGGGATTTACCCAACTTCAGCTAACTTCTCAACAGACTTACACTCACTTGGTCAATTT
ATCCAAGAAGGTTACCGTAACCTCTTTGAAACAGTTATTCGTGTTGATAAACCTCGTAAAAATGTTATCATTCCTGAATT
AGCAGAAGACCTAGATGGACTTGGTTACCTTCAAGGTAAAGACGTTGATTTCGTTAACAAGAAAGCTACAGATGGTGTGC
TTCTTGCCCACACAGATGGCGGCGTGCCAAACATGTTTGTCACTCTTCCAGCTCAAGACGAATTTACTCTTGGTTACACT
ATTTACTTCTTTGAGCTTGCTATCGCTGTTTCAGGCTACATGAATGCTGTTAACCCATTTGATCAGCCAGGTGTTGAAGC
TTACAAACGTAACATGTTTGCGCTTCTTGGAAAACCAGGTTTTGAAGAATTATCAGCAGAGCTTAACGCTCGCCTCTAA

Upstream 100 bases:

>100_bases
TCAAAAAACCTAGCTTTTTCACAGGTGAAAACCACTAAAAACCATTGAAATATTAGATAGAAAAGGTTATCATACTAATG
AAACTTAAAATTTTAAGGGA

Downstream 100 bases:

>100_bases
TAAACAGATAGTCAAAAAGACTTCTTCCTTGTACAAGAGCTTAAAAGTTAGCCAAGCAATCTAAGAATTGGGGTGGCACT
TCCATCATCAAGTGGATACA

Product: glucose-6-phosphate isomerase

Products: NA

Alternate protein names: GPI; Phosphoglucose isomerase; PGI; Phosphohexose isomerase; PHI [H]

Number of amino acids: Translated: 452; Mature: 452

Protein sequence:

>452_residues
MKLMSHITFDYSKVLESFAGQHEIDFLQGQVTEADKLLREGTGPGSDFLGWLDLPENYDKDEFARILTAAEKIKSDSEVL
VVIGIGGSYLGAKAAIDFLNHHFANLQTAKERKAPQILYAGNSISSTYLADLVEYVQDKEFSVNVISKSGTTTEPAIAFR
VFKELLVKKYGQEEANKRIYATTDKVKGAVKVEADANNWETFVVPDNVGGRFSVLTAVGLLPIAASGADITALMEGANAA
RKDLSSDKISENIAYQYAAVRNVLYRKGYITEILANYEPSLQYFGEWWKQLAGESEGKDQKGIYPTSANFSTDLHSLGQF
IQEGYRNLFETVIRVDKPRKNVIIPELAEDLDGLGYLQGKDVDFVNKKATDGVLLAHTDGGVPNMFVTLPAQDEFTLGYT
IYFFELAIAVSGYMNAVNPFDQPGVEAYKRNMFALLGKPGFEELSAELNARL

Sequences:

>Translated_452_residues
MKLMSHITFDYSKVLESFAGQHEIDFLQGQVTEADKLLREGTGPGSDFLGWLDLPENYDKDEFARILTAAEKIKSDSEVL
VVIGIGGSYLGAKAAIDFLNHHFANLQTAKERKAPQILYAGNSISSTYLADLVEYVQDKEFSVNVISKSGTTTEPAIAFR
VFKELLVKKYGQEEANKRIYATTDKVKGAVKVEADANNWETFVVPDNVGGRFSVLTAVGLLPIAASGADITALMEGANAA
RKDLSSDKISENIAYQYAAVRNVLYRKGYITEILANYEPSLQYFGEWWKQLAGESEGKDQKGIYPTSANFSTDLHSLGQF
IQEGYRNLFETVIRVDKPRKNVIIPELAEDLDGLGYLQGKDVDFVNKKATDGVLLAHTDGGVPNMFVTLPAQDEFTLGYT
IYFFELAIAVSGYMNAVNPFDQPGVEAYKRNMFALLGKPGFEELSAELNARL
>Mature_452_residues
MKLMSHITFDYSKVLESFAGQHEIDFLQGQVTEADKLLREGTGPGSDFLGWLDLPENYDKDEFARILTAAEKIKSDSEVL
VVIGIGGSYLGAKAAIDFLNHHFANLQTAKERKAPQILYAGNSISSTYLADLVEYVQDKEFSVNVISKSGTTTEPAIAFR
VFKELLVKKYGQEEANKRIYATTDKVKGAVKVEADANNWETFVVPDNVGGRFSVLTAVGLLPIAASGADITALMEGANAA
RKDLSSDKISENIAYQYAAVRNVLYRKGYITEILANYEPSLQYFGEWWKQLAGESEGKDQKGIYPTSANFSTDLHSLGQF
IQEGYRNLFETVIRVDKPRKNVIIPELAEDLDGLGYLQGKDVDFVNKKATDGVLLAHTDGGVPNMFVTLPAQDEFTLGYT
IYFFELAIAVSGYMNAVNPFDQPGVEAYKRNMFALLGKPGFEELSAELNARL

Specific function: Involved in glycolysis and in gluconeogenesis. [C]

COG id: COG0166

COG function: function code G; Glucose-6-phosphate isomerase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GPI family [H]

Homologues:

Organism=Saccharomyces cerevisiae, GI6319673, Length=375, Percent_Identity=25.3333333333333, Blast_Score=70, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001672
- InterPro:   IPR018189 [H]

Pfam domain/function: PF00342 PGI [H]

EC number: =5.3.1.9 [H]

Molecular weight: Translated: 49914; Mature: 49914

Theoretical pI: Translated: 4.68; Mature: 4.68

Prosite motif: PS00765 P_GLUCOSE_ISOMERASE_1 ; PS00174 P_GLUCOSE_ISOMERASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLMSHITFDYSKVLESFAGQHEIDFLQGQVTEADKLLREGTGPGSDFLGWLDLPENYDK
CCHHHHHHHHHHHHHHHHCCCCCHHHHHCCHHHHHHHHHCCCCCCCCCCEEECCCCCCCH
DEFARILTAAEKIKSDSEVLVVIGIGGSYLGAKAAIDFLNHHFANLQTAKERKAPQILYA
HHHHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEE
GNSISSTYLADLVEYVQDKEFSVNVISKSGTTTEPAIAFRVFKELLVKKYGQEEANKRIY
CCCCCHHHHHHHHHHHCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHCHHHHCCEEE
ATTDKVKGAVKVEADANNWETFVVPDNVGGRFSVLTAVGLLPIAASGADITALMEGANAA
EEHHHCCCEEEEEECCCCCEEEEEECCCCCHHHHHHHHHHHHHCCCCCCHHHHHHCCHHH
RKDLSSDKISENIAYQYAAVRNVLYRKGYITEILANYEPSLQYFGEWWKQLAGESEGKDQ
HHCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCC
KGIYPTSANFSTDLHSLGQFIQEGYRNLFETVIRVDKPRKNVIIPELAEDLDGLGYLQGK
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHCCCCCCCCCCC
DVDFVNKKATDGVLLAHTDGGVPNMFVTLPAQDEFTLGYTIYFFELAIAVSGYMNAVNPF
CCCCCCCCCCCCEEEEECCCCCCCEEEEECCCCCEEEHHHHHHHHHHHHHHHHHHHCCCC
DQPGVEAYKRNMFALLGKPGFEELSAELNARL
CCCCHHHHHHHHHHHHCCCCHHHHHHHHHCCC
>Mature Secondary Structure
MKLMSHITFDYSKVLESFAGQHEIDFLQGQVTEADKLLREGTGPGSDFLGWLDLPENYDK
CCHHHHHHHHHHHHHHHHCCCCCHHHHHCCHHHHHHHHHCCCCCCCCCCEEECCCCCCCH
DEFARILTAAEKIKSDSEVLVVIGIGGSYLGAKAAIDFLNHHFANLQTAKERKAPQILYA
HHHHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEE
GNSISSTYLADLVEYVQDKEFSVNVISKSGTTTEPAIAFRVFKELLVKKYGQEEANKRIY
CCCCCHHHHHHHHHHHCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHCHHHHCCEEE
ATTDKVKGAVKVEADANNWETFVVPDNVGGRFSVLTAVGLLPIAASGADITALMEGANAA
EEHHHCCCEEEEEECCCCCEEEEEECCCCCHHHHHHHHHHHHHCCCCCCHHHHHHCCHHH
RKDLSSDKISENIAYQYAAVRNVLYRKGYITEILANYEPSLQYFGEWWKQLAGESEGKDQ
HHCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCC
KGIYPTSANFSTDLHSLGQFIQEGYRNLFETVIRVDKPRKNVIIPELAEDLDGLGYLQGK
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHCCCCCCCCCCC
DVDFVNKKATDGVLLAHTDGGVPNMFVTLPAQDEFTLGYTIYFFELAIAVSGYMNAVNPF
CCCCCCCCCCCCEEEEECCCCCCCEEEEECCCCCEEEHHHHHHHHHHHHHHHHHHHCCCC
DQPGVEAYKRNMFALLGKPGFEELSAELNARL
CCCCHHHHHHHHHHHHCCCCHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA