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The map label for this gene is copA [H]

Identifier: 94972058

GI number: 94972058

Start: 464504

End: 466084

Strand: Direct

Name: copA [H]

Synonym: Dgeo_2590

Alternate gene names: 94972058

Gene position: 464504-466084 (Clockwise)

Preceding gene: 94972059

Following gene: 94972057

Centisome position: 80.91

GC content: 59.52

Gene sequence:

>1581_bases
ATGCTGACTTTCATTCAACCGATTGACCCGTTCGTGCTGGGCTGGTTGGCGCTATGCATCCTCTCGGCGTTGTACGTCGC
TTACGATCAGTTCAGGAACAACCCGGAACCGACGGTCATGCGCTGGGCTTTCATTCTGACCACGCTTTACATGGGGCCAA
TCGGTCTGCTGCTGTACGTCATGGCCGACAAGGAACCCAAACCCGGCACGCACGAGCAGTTCACCCGGCCCCTCTGGAAG
CAGGGCGTGGGCAGCACCATGCACTGCGTGGCCGGGGACGCCACCGGGATTATCCTCTCGGCGCTGATCGTGATTTCACT
GGGCCTGCCGATGAAGTGGGATTTGGTGGTGGAGTATCTGGCGGGCTTCATGGTGGGCCTGTTCGTGTTTCAGGCGCTGT
TCATGAAAAGTTCGATGGGCGGCAGCTACTGGGAAAATGTAAAACGTTCCTTCCTGCCCGAACTGATTTCGATGAATTTC
ATGATGGCTGGAATGGCCCCCGTGATGGTCTTTCTGATGATGGGGCGGGATATGCGGGCCATGCAGCCCACTGAGCCGCT
CTTCTGGGCCGTGATGAGCCTGGGTGTGATCGCCGGGTTCGCGCTGGCTTACCCGGTGAATGTCTGGATGGTCTCGCGCA
ACATGAAACACGGCCTGATGACCGAGCGCCCCTCAGGAAGTCGTTTTGATGTCCCAAGTCAACCTCTGGAACCGCAGAAC
GTAAACCACCTGAACCGTTCGCAGGGCAAAGTAGTGCAAGCACCCCAGGGACACGAAGCGGCGGGTTCAGCGTCCCATGC
GGGTCACCACATGCCTGAGCAGGATCATGCCCAGATGAACCATGCAGAGCACGCCGCACACGTTCAGGTTACTCAGGCGC
ACGCCCACATGGGACATGGCACACCGCCTGAGCAGGCAACTGCCAGCAGTCCCGATCACGCCGCTATGGGCCACGAAGGT
CACCAGATGCAACCTAATGTCACTCGCCCTCAACTGCTGTCGGTGGGCCTCATCAGTGGATTGCTCCTGCTCCTCGGCAT
GACCTGGCCTGCCACCAAGGTGAACGTCAATATTGCCGCGCACGAGGTCGGGAGTGCCATCATGCCGCCTGGCATGATCA
TGACCCCCGATACGCCAGCGGACGCCATGAAGGACATGTCTGCGGTAGACCCGCGCCTCTTCCGCTTCCGTGCAGCCGTG
ACCCAGCAGGGCGACCAGACCCTTGAACCCGCCGTTCAGGGCGGCGTGAAAAGGTTTAACCTGACCGTCAGCGCCGGGCA
GTGGAACATCCTGAAAGACCGCCCCGTGGGAGCCTATGCCATTAACGGTCAGGTGCCAGGGCCACGCCTTGAACTGGAGC
AGGGAGATCAGGTGGAGATCGTGGTCAAGAATGACCTTCCAGAAAGCACCACCCTGCACTGGCATGGCCTGATCCTCGAC
AACGAGATGGACGGCCCCGCCCACATCACCCAGAAGCCTATTAAACCGGGGGGAAGTTACACTTACCGCTTTACTGCCGT
GCAGGCCGGAACTTATTTCGTGACTACTCAGCAGGGGGAGTTGATGTCTGCGGCAAGGTAG

Upstream 100 bases:

>100_bases
GGACGAATCTCGCCATGATTTACCTGCGCCCCGGTTACGAGCGGGCCGAGGAAGTCCTCACCCGCCTGTCCGAGGCGCTG
CGGCCCATCTGAGGACGGTC

Downstream 100 bases:

>100_bases
AGTAGGGCATCACACAGGACGCCTGCCCGAACTGCCAACGACTGGAAGCTGAACTTGTGCAGCTTCGTCAGGAACTTGAG
CGTCTGAAGGCAGAGCTACG

Product: multicopper oxidase, type 3

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 526; Mature: 526

Protein sequence:

>526_residues
MLTFIQPIDPFVLGWLALCILSALYVAYDQFRNNPEPTVMRWAFILTTLYMGPIGLLLYVMADKEPKPGTHEQFTRPLWK
QGVGSTMHCVAGDATGIILSALIVISLGLPMKWDLVVEYLAGFMVGLFVFQALFMKSSMGGSYWENVKRSFLPELISMNF
MMAGMAPVMVFLMMGRDMRAMQPTEPLFWAVMSLGVIAGFALAYPVNVWMVSRNMKHGLMTERPSGSRFDVPSQPLEPQN
VNHLNRSQGKVVQAPQGHEAAGSASHAGHHMPEQDHAQMNHAEHAAHVQVTQAHAHMGHGTPPEQATASSPDHAAMGHEG
HQMQPNVTRPQLLSVGLISGLLLLLGMTWPATKVNVNIAAHEVGSAIMPPGMIMTPDTPADAMKDMSAVDPRLFRFRAAV
TQQGDQTLEPAVQGGVKRFNLTVSAGQWNILKDRPVGAYAINGQVPGPRLELEQGDQVEIVVKNDLPESTTLHWHGLILD
NEMDGPAHITQKPIKPGGSYTYRFTAVQAGTYFVTTQQGELMSAAR

Sequences:

>Translated_526_residues
MLTFIQPIDPFVLGWLALCILSALYVAYDQFRNNPEPTVMRWAFILTTLYMGPIGLLLYVMADKEPKPGTHEQFTRPLWK
QGVGSTMHCVAGDATGIILSALIVISLGLPMKWDLVVEYLAGFMVGLFVFQALFMKSSMGGSYWENVKRSFLPELISMNF
MMAGMAPVMVFLMMGRDMRAMQPTEPLFWAVMSLGVIAGFALAYPVNVWMVSRNMKHGLMTERPSGSRFDVPSQPLEPQN
VNHLNRSQGKVVQAPQGHEAAGSASHAGHHMPEQDHAQMNHAEHAAHVQVTQAHAHMGHGTPPEQATASSPDHAAMGHEG
HQMQPNVTRPQLLSVGLISGLLLLLGMTWPATKVNVNIAAHEVGSAIMPPGMIMTPDTPADAMKDMSAVDPRLFRFRAAV
TQQGDQTLEPAVQGGVKRFNLTVSAGQWNILKDRPVGAYAINGQVPGPRLELEQGDQVEIVVKNDLPESTTLHWHGLILD
NEMDGPAHITQKPIKPGGSYTYRFTAVQAGTYFVTTQQGELMSAAR
>Mature_526_residues
MLTFIQPIDPFVLGWLALCILSALYVAYDQFRNNPEPTVMRWAFILTTLYMGPIGLLLYVMADKEPKPGTHEQFTRPLWK
QGVGSTMHCVAGDATGIILSALIVISLGLPMKWDLVVEYLAGFMVGLFVFQALFMKSSMGGSYWENVKRSFLPELISMNF
MMAGMAPVMVFLMMGRDMRAMQPTEPLFWAVMSLGVIAGFALAYPVNVWMVSRNMKHGLMTERPSGSRFDVPSQPLEPQN
VNHLNRSQGKVVQAPQGHEAAGSASHAGHHMPEQDHAQMNHAEHAAHVQVTQAHAHMGHGTPPEQATASSPDHAAMGHEG
HQMQPNVTRPQLLSVGLISGLLLLLGMTWPATKVNVNIAAHEVGSAIMPPGMIMTPDTPADAMKDMSAVDPRLFRFRAAV
TQQGDQTLEPAVQGGVKRFNLTVSAGQWNILKDRPVGAYAINGQVPGPRLELEQGDQVEIVVKNDLPESTTLHWHGLILD
NEMDGPAHITQKPIKPGGSYTYRFTAVQAGTYFVTTQQGELMSAAR

Specific function: Could be involved in copper resistance. May have oxidase activity [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the multicopper oxidase family. CopA subfamily [H]

Homologues:

Organism=Drosophila melanogaster, GI28574104, Length=82, Percent_Identity=43.9024390243902, Blast_Score=68, Evalue=2e-11,
Organism=Drosophila melanogaster, GI18859919, Length=73, Percent_Identity=45.2054794520548, Blast_Score=66, Evalue=5e-11,

Paralogues:

None

Copy number: 40 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001117
- InterPro:   IPR011706
- InterPro:   IPR011707
- InterPro:   IPR006376
- InterPro:   IPR002355
- InterPro:   IPR008972
- InterPro:   IPR006311 [H]

Pfam domain/function: PF00394 Cu-oxidase; PF07731 Cu-oxidase_2; PF07732 Cu-oxidase_3 [H]

EC number: NA

Molecular weight: Translated: 57599; Mature: 57599

Theoretical pI: Translated: 6.83; Mature: 6.83

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
6.7 %Met     (Translated Protein)
7.0 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
6.7 %Met     (Mature Protein)
7.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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CCCCCCCCCCCCCCCCCCCEEEEEEEEECCEEEEEECCCCHHHCCC
>Mature Secondary Structure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CCCCCCCCCCCCCCCCCCCEEEEEEEEECCEEEEEECCCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12928499 [H]