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The map label for this gene is actP [H]

Identifier: 94314702

GI number: 94314702

Start: 2541242

End: 2542903

Strand: Direct

Name: actP [H]

Synonym: Rmet_5783

Alternate gene names: 94314702

Gene position: 2541242-2542903 (Clockwise)

Preceding gene: 94314701

Following gene: 94314704

Centisome position: 98.49

GC content: 63.54

Gene sequence:

>1662_bases
ATGAAAACGCATCACGTTATCGCCGCAGGCGGCGCATTGCTGTTGTCGACGGCCGCGCTGGCCGCGGGTGGTGATCTTGG
ACAGGCCGTCAAACAGCCCACCAACTGGACGGCCATCGGCATGTTCGTCGTGTTCGTCATCGGCACGCTGTTCATCACCA
AATGGGCGGCCAAGCGGACCACGTCCGCGGCGGCGTTCTATACGGGCGGTGGTGGCATCACCGGCTTCCAGAACGGCCTG
GCCATCGCTGGCGACTACATGTCGGCAGCATCGTTCCTCGGCATTTCCGCCGCCGTGTTCGCAAACGGCTACGACGGCCT
GATCTACTCGATCGGCTTCCTGGTCGGCTGGCCAATCATCACGTTCCTGATGGCGGAGCGCCTGCGCAACCTCGGCCGTT
TCACGTTTGCCGATGTGGCCGCCTACCGCTTCAAGCAGGGCCCGATCCGCGCGTTCGCGGCGTCGGGCACGCTGGTGGTG
GTGGCGTTCTACCTGATCGCGCAGATGGTGGGCGCCGGGCAACTGATCAAGCTGCTGTTCGGGCTCGAGTACTGGATCGC
GGTGGTGATCGTTGGCGCGCTGATGATGGTGTACGTGCTGTTCGGCGGCATGACGGCAACCACCTGGGTGCAGATCATCA
AGGCTGGCCTGCTGCTGGGCGGCGCATCATTCATGGCCTTCATGGTCATGGCGCAGTTCCACTTCAGCCCCGAAGCACTG
TTCGCCAAGGCCGTTGAAGTCCATGCCAAGAAGGACGCGATCATGGGCCCGGGCACATTCATCAAGGACCCGATTTCGGC
GATCTCATTCGGCATCGCGCTGATGTTCGGCACGGCCGGCCTGCCGCACGTCCTGATGCGATTCTTCACCGTGCCCAATG
CCAAGGAAGCGCGCAAGTCCGTGTTCTGGGCCACCACGTGGATCGGCTACTTCTACATCCTGACGTTCATCATCGGCTTC
GGCGCCATCGTGCTGGTGAGCACCAACCCGACGTTCCAGGACGGTAGCGGCAAGCTGCTCGGCGGCCTCAACATGGCGGC
CGTTCACCTGGCCACTGCAGTGGGCGGCAACGTGTTCCTCGGGTTCATCTCGGCGGTGGCGTTCGCGACAATCCTGGCCG
TGGTGGCCGGCCTCACGCTGGCCGGCGCGTCGGCGGTGTCGCACGACCTGTACTCCACGGTCTTCATGCACGGCAAGGCA
ACCAGTTCGATGGAACTGCGCGTGTCGCGCATCACCACGATCATCCTCGGCATCATCGCCGTGGTGCTCGGCATCGTCTT
CGAGAAGCAGAACATCGCGTTCATGGTGTCGCTGGCGTTCGCCGTGGCGGCATCGGCCAACTTCCCGGTCCTGTTCATGT
CGGTGCTGTGGAAGAACTGCACCACGCGCGGCGCGATGGTTGGCGGCTTCCTCGGCCTGCTGTCAGCCGTGATTCTGACG
GTCCTGTCCCAGGCGGTGTGGGTCGACGTGTTCCACTTCAAGAATGCGCCATTCCCGTACACGTCTCCGGCGCTGTTCTC
AATGACGATCGGCTTCGTCGGCATCTGGTTCTTCTCGATCACCGACAGGTCACCCCGGGCACGTATCGACCGTGCCGGCT
TCGAGGCACAGGAACTGCGTTCCGAGACCGGCATCGGCGCCGTCGGGGCCGCAAGCCACTGA

Upstream 100 bases:

>100_bases
TGTTCGTGATCGTCTTCACCGTCGTCATCACGGGGCTCTACGTGCGTCATGCCAACAACACCTATGACGAGCTCACCGAG
CAGATCAAGCGGGAGGTCGC

Downstream 100 bases:

>100_bases
TCCGCCCGGCGTCGCCCTCCCGCGGCGCCTACGGCAACTGCTTGCCGGGCAGCGTGGGTGTCACGCCACGCGTGCCTGCG
GCGGGCACACGGCGCGTGCC

Product: acetate permease

Products: NA

Alternate protein names: Acetate permease; Acetate transporter ActP [H]

Number of amino acids: Translated: 553; Mature: 553

Protein sequence:

>553_residues
MKTHHVIAAGGALLLSTAALAAGGDLGQAVKQPTNWTAIGMFVVFVIGTLFITKWAAKRTTSAAAFYTGGGGITGFQNGL
AIAGDYMSAASFLGISAAVFANGYDGLIYSIGFLVGWPIITFLMAERLRNLGRFTFADVAAYRFKQGPIRAFAASGTLVV
VAFYLIAQMVGAGQLIKLLFGLEYWIAVVIVGALMMVYVLFGGMTATTWVQIIKAGLLLGGASFMAFMVMAQFHFSPEAL
FAKAVEVHAKKDAIMGPGTFIKDPISAISFGIALMFGTAGLPHVLMRFFTVPNAKEARKSVFWATTWIGYFYILTFIIGF
GAIVLVSTNPTFQDGSGKLLGGLNMAAVHLATAVGGNVFLGFISAVAFATILAVVAGLTLAGASAVSHDLYSTVFMHGKA
TSSMELRVSRITTIILGIIAVVLGIVFEKQNIAFMVSLAFAVAASANFPVLFMSVLWKNCTTRGAMVGGFLGLLSAVILT
VLSQAVWVDVFHFKNAPFPYTSPALFSMTIGFVGIWFFSITDRSPRARIDRAGFEAQELRSETGIGAVGAASH

Sequences:

>Translated_553_residues
MKTHHVIAAGGALLLSTAALAAGGDLGQAVKQPTNWTAIGMFVVFVIGTLFITKWAAKRTTSAAAFYTGGGGITGFQNGL
AIAGDYMSAASFLGISAAVFANGYDGLIYSIGFLVGWPIITFLMAERLRNLGRFTFADVAAYRFKQGPIRAFAASGTLVV
VAFYLIAQMVGAGQLIKLLFGLEYWIAVVIVGALMMVYVLFGGMTATTWVQIIKAGLLLGGASFMAFMVMAQFHFSPEAL
FAKAVEVHAKKDAIMGPGTFIKDPISAISFGIALMFGTAGLPHVLMRFFTVPNAKEARKSVFWATTWIGYFYILTFIIGF
GAIVLVSTNPTFQDGSGKLLGGLNMAAVHLATAVGGNVFLGFISAVAFATILAVVAGLTLAGASAVSHDLYSTVFMHGKA
TSSMELRVSRITTIILGIIAVVLGIVFEKQNIAFMVSLAFAVAASANFPVLFMSVLWKNCTTRGAMVGGFLGLLSAVILT
VLSQAVWVDVFHFKNAPFPYTSPALFSMTIGFVGIWFFSITDRSPRARIDRAGFEAQELRSETGIGAVGAASH
>Mature_553_residues
MKTHHVIAAGGALLLSTAALAAGGDLGQAVKQPTNWTAIGMFVVFVIGTLFITKWAAKRTTSAAAFYTGGGGITGFQNGL
AIAGDYMSAASFLGISAAVFANGYDGLIYSIGFLVGWPIITFLMAERLRNLGRFTFADVAAYRFKQGPIRAFAASGTLVV
VAFYLIAQMVGAGQLIKLLFGLEYWIAVVIVGALMMVYVLFGGMTATTWVQIIKAGLLLGGASFMAFMVMAQFHFSPEAL
FAKAVEVHAKKDAIMGPGTFIKDPISAISFGIALMFGTAGLPHVLMRFFTVPNAKEARKSVFWATTWIGYFYILTFIIGF
GAIVLVSTNPTFQDGSGKLLGGLNMAAVHLATAVGGNVFLGFISAVAFATILAVVAGLTLAGASAVSHDLYSTVFMHGKA
TSSMELRVSRITTIILGIIAVVLGIVFEKQNIAFMVSLAFAVAASANFPVLFMSVLWKNCTTRGAMVGGFLGLLSAVILT
VLSQAVWVDVFHFKNAPFPYTSPALFSMTIGFVGIWFFSITDRSPRARIDRAGFEAQELRSETGIGAVGAASH

Specific function: Transports acetate [H]

COG id: COG4147

COG function: function code R; Predicted symporter

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family [H]

Homologues:

Organism=Homo sapiens, GI310128183, Length=458, Percent_Identity=22.2707423580786, Blast_Score=75, Evalue=1e-13,
Organism=Escherichia coli, GI1790503, Length=539, Percent_Identity=68.0890538033395, Blast_Score=718, Evalue=0.0,
Organism=Escherichia coli, GI1787251, Length=510, Percent_Identity=24.3137254901961, Blast_Score=87, Evalue=4e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014083
- InterPro:   IPR001734
- InterPro:   IPR018212
- InterPro:   IPR019900 [H]

Pfam domain/function: PF00474 SSF [H]

EC number: NA

Molecular weight: Translated: 58483; Mature: 58483

Theoretical pI: Translated: 10.25; Mature: 10.25

Prosite motif: PS00456 NA_SOLUT_SYMP_1 ; PS50283 NA_SOLUT_SYMP_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTHHVIAAGGALLLSTAALAAGGDLGQAVKQPTNWTAIGMFVVFVIGTLFITKWAAKRT
CCCCEEEEECHHHHHHHHHHHCCCCHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCC
TSAAAFYTGGGGITGFQNGLAIAGDYMSAASFLGISAAVFANGYDGLIYSIGFLVGWPII
CCCEEEEECCCCCCCCCCCCEEECHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHH
TFLMAERLRNLGRFTFADVAAYRFKQGPIRAFAASGTLVVVAFYLIAQMVGAGQLIKLLF
HHHHHHHHHHCCCHHHHHHHHHHHCCCCCHHEECCCHHHHHHHHHHHHHHCHHHHHHHHH
GLEYWIAVVIVGALMMVYVLFGGMTATTWVQIIKAGLLLGGASFMAFMVMAQFHFSPEAL
HHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHH
FAKAVEVHAKKDAIMGPGTFIKDPISAISFGIALMFGTAGLPHVLMRFFTVPNAKEARKS
HHHHHHHHHHHCCCCCCCCHHHCHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCHHHHHHH
VFWATTWIGYFYILTFIIGFGAIVLVSTNPTFQDGSGKLLGGLNMAAVHLATAVGGNVFL
HHHHHHHHHHHHHHHHHHHCCEEEEEECCCCCCCCCCCEECCCHHHHHHHHHHHCHHHHH
GFISAVAFATILAVVAGLTLAGASAVSHDLYSTVFMHGKATSSMELRVSRITTIILGIIA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHH
VVLGIVFEKQNIAFMVSLAFAVAASANFPVLFMSVLWKNCTTRGAMVGGFLGLLSAVILT
HHHHHHHCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
VLSQAVWVDVFHFKNAPFPYTSPALFSMTIGFVGIWFFSITDRSPRARIDRAGFEAQELR
HHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHCCCCHHHHH
SETGIGAVGAASH
HHCCCCCCCCCCC
>Mature Secondary Structure
MKTHHVIAAGGALLLSTAALAAGGDLGQAVKQPTNWTAIGMFVVFVIGTLFITKWAAKRT
CCCCEEEEECHHHHHHHHHHHCCCCHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCC
TSAAAFYTGGGGITGFQNGLAIAGDYMSAASFLGISAAVFANGYDGLIYSIGFLVGWPII
CCCEEEEECCCCCCCCCCCCEEECHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHH
TFLMAERLRNLGRFTFADVAAYRFKQGPIRAFAASGTLVVVAFYLIAQMVGAGQLIKLLF
HHHHHHHHHHCCCHHHHHHHHHHHCCCCCHHEECCCHHHHHHHHHHHHHHCHHHHHHHHH
GLEYWIAVVIVGALMMVYVLFGGMTATTWVQIIKAGLLLGGASFMAFMVMAQFHFSPEAL
HHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHH
FAKAVEVHAKKDAIMGPGTFIKDPISAISFGIALMFGTAGLPHVLMRFFTVPNAKEARKS
HHHHHHHHHHHCCCCCCCCHHHCHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCHHHHHHH
VFWATTWIGYFYILTFIIGFGAIVLVSTNPTFQDGSGKLLGGLNMAAVHLATAVGGNVFL
HHHHHHHHHHHHHHHHHHHCCEEEEEECCCCCCCCCCCEECCCHHHHHHHHHHHCHHHHH
GFISAVAFATILAVVAGLTLAGASAVSHDLYSTVFMHGKATSSMELRVSRITTIILGIIA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHH
VVLGIVFEKQNIAFMVSLAFAVAASANFPVLFMSVLWKNCTTRGAMVGGFLGLLSAVILT
HHHHHHHCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
VLSQAVWVDVFHFKNAPFPYTSPALFSMTIGFVGIWFFSITDRSPRARIDRAGFEAQELR
HHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHCCCCHHHHH
SETGIGAVGAASH
HHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA