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The map label for this gene is bvgA [H]

Identifier: 94314633

GI number: 94314633

Start: 2472968

End: 2473600

Strand: Reverse

Name: bvgA [H]

Synonym: Rmet_5714

Alternate gene names: 94314633

Gene position: 2473600-2472968 (Counterclockwise)

Preceding gene: 94314634

Following gene: 94314632

Centisome position: 95.87

GC content: 55.45

Gene sequence:

>633_bases
ATGATTACCGTCCTCATTGTCGACGATCACCCAGCAGTCCGACTCGTTATCAAAACGCAGCTATCGCAAGTGCTCGGCGT
TTCATCCGTGCTGGAAGCCGACAACGGCCAGGCGGCGATCGACGTTGTGCGGCAGTGCAAGCCCGATCTGGTTATCCTAG
ATCTCGATATTCCAAAGATCAATGGGCTTGAGGTGATCCCCCGCCTGAAGGCCATCCAGCCCAATATCCGGGTGCTCGTG
ATTTCGGGGCAGGATCCGATGACCTTTGCTCCTCGCGCCATGCAGGTGGGCGCAAAGGGCTTCGTCAGCAAGATGCAGGA
CATGACGGACATCATGCGCTGTGTGGAATCTGTCCTGGCAGGCTATACGCTCTTTCCCGCCGAGGTGGTTGAATCCGGTG
CCGTGCCCGGCAAGGCCCGCGAAGATAGCGAACTGCTGCAGCAACTGACTGACAAGGAGATTCAGATCATGCAGATGCTG
AGCAAGGGAATGTCGAACAAGGCCATTGGAGACTCGCTCTTCATCAGTAACAAGACCGTGAGTAGCCACAAAACGCGCAT
CATGGAAAAGTTACACGTCACGACGTTGCTGGAACTGATCGATTTTGCGCGGCGCTGCAATATTGCACCTTGA

Upstream 100 bases:

>100_bases
TCCTAGCGTATGGCAATGACAATAATCCATGGGGAAGCTACGAATTTTCCCGTGGTTCGATCAGTCATTGAACCGCCTTA
CAGGTATGGAGAAGTCAAAG

Downstream 100 bases:

>100_bases
GATGAGGTGTCGCTATGTCACGGGTGATCATCTCAGGTGAGGAATGGAGTGGCGCGGAGCGCGATGAACTCGCTGCAAGT
CTGACGTCACTGGGGCTATT

Product: LuxR family two component transcriptional regulator (receiver domain) (bvgA-like)

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 210; Mature: 210

Protein sequence:

>210_residues
MITVLIVDDHPAVRLVIKTQLSQVLGVSSVLEADNGQAAIDVVRQCKPDLVILDLDIPKINGLEVIPRLKAIQPNIRVLV
ISGQDPMTFAPRAMQVGAKGFVSKMQDMTDIMRCVESVLAGYTLFPAEVVESGAVPGKAREDSELLQQLTDKEIQIMQML
SKGMSNKAIGDSLFISNKTVSSHKTRIMEKLHVTTLLELIDFARRCNIAP

Sequences:

>Translated_210_residues
MITVLIVDDHPAVRLVIKTQLSQVLGVSSVLEADNGQAAIDVVRQCKPDLVILDLDIPKINGLEVIPRLKAIQPNIRVLV
ISGQDPMTFAPRAMQVGAKGFVSKMQDMTDIMRCVESVLAGYTLFPAEVVESGAVPGKAREDSELLQQLTDKEIQIMQML
SKGMSNKAIGDSLFISNKTVSSHKTRIMEKLHVTTLLELIDFARRCNIAP
>Mature_210_residues
MITVLIVDDHPAVRLVIKTQLSQVLGVSSVLEADNGQAAIDVVRQCKPDLVILDLDIPKINGLEVIPRLKAIQPNIRVLV
ISGQDPMTFAPRAMQVGAKGFVSKMQDMTDIMRCVESVLAGYTLFPAEVVESGAVPGKAREDSELLQQLTDKEIQIMQML
SKGMSNKAIGDSLFISNKTVSSHKTRIMEKLHVTTLLELIDFARRCNIAP

Specific function: Member of the two-component regulatory system BvgS/BvgA. Activates the transcription of virulence genes [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1786747, Length=202, Percent_Identity=39.1089108910891, Blast_Score=161, Evalue=4e-41,
Organism=Escherichia coli, GI1788712, Length=213, Percent_Identity=34.7417840375587, Blast_Score=134, Evalue=5e-33,
Organism=Escherichia coli, GI1788222, Length=211, Percent_Identity=30.3317535545024, Blast_Score=106, Evalue=9e-25,
Organism=Escherichia coli, GI1790102, Length=209, Percent_Identity=30.1435406698565, Blast_Score=82, Evalue=2e-17,
Organism=Escherichia coli, GI1788521, Length=194, Percent_Identity=28.3505154639175, Blast_Score=80, Evalue=9e-17,
Organism=Escherichia coli, GI1787473, Length=183, Percent_Identity=30.6010928961749, Blast_Score=75, Evalue=4e-15,
Organism=Escherichia coli, GI1788546, Length=215, Percent_Identity=24.1860465116279, Blast_Score=62, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001789
- InterPro:   IPR011990
- InterPro:   IPR000792
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00196 GerE; PF00072 Response_reg [H]

EC number: NA

Molecular weight: Translated: 23018; Mature: 23018

Theoretical pI: Translated: 6.78; Mature: 6.78

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS00622 HTH_LUXR_1 ; PS50043 HTH_LUXR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
4.8 %Met     (Translated Protein)
6.2 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
4.8 %Met     (Mature Protein)
6.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MITVLIVDDHPAVRLVIKTQLSQVLGVSSVLEADNGQAAIDVVRQCKPDLVILDLDIPKI
CEEEEEECCCCCEEHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCEEEEECCCCCC
NGLEVIPRLKAIQPNIRVLVISGQDPMTFAPRAMQVGAKGFVSKMQDMTDIMRCVESVLA
CCHHHHHHHHHCCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
GYTLFPAEVVESGAVPGKAREDSELLQQLTDKEIQIMQMLSKGMSNKAIGDSLFISNKTV
CCCCCHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEECCCCH
SSHKTRIMEKLHVTTLLELIDFARRCNIAP
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MITVLIVDDHPAVRLVIKTQLSQVLGVSSVLEADNGQAAIDVVRQCKPDLVILDLDIPKI
CEEEEEECCCCCEEHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCEEEEECCCCCC
NGLEVIPRLKAIQPNIRVLVISGQDPMTFAPRAMQVGAKGFVSKMQDMTDIMRCVESVLA
CCHHHHHHHHHCCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
GYTLFPAEVVESGAVPGKAREDSELLQQLTDKEIQIMQMLSKGMSNKAIGDSLFISNKTV
CCCCCHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEECCCCH
SSHKTRIMEKLHVTTLLELIDFARRCNIAP
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1791760; 12910271 [H]