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The map label for this gene is ompR [H]

Identifier: 94314626

GI number: 94314626

Start: 2464563

End: 2465396

Strand: Direct

Name: ompR [H]

Synonym: Rmet_5707

Alternate gene names: 94314626

Gene position: 2464563-2465396 (Clockwise)

Preceding gene: 291481602

Following gene: 94314629

Centisome position: 95.52

GC content: 62.23

Gene sequence:

>834_bases
ATGGATCACTCCTTTCATCGGAAATTTCCGAATCGCCCTGCTGAATGGCTTTGCTACTCTCAATCGATTCAGCATGAATG
CGCCCCCATAGCCGGGGCGCCTGGCTTTCGGAAGTTGAAAGTGAACTCGATCAAGATCGCACTGCTTGACGCGGAGCCAT
CGTCCGCGACCGGCATCAGCAAAGTGCTGGAAGCCGGCGGTGTTGTATCGTCCCGCTTTACCAGTTCCGAAAGGTTGTTT
CGGGAGCTCCGGCGTTCTGTATTCGATGTGGTACTGGTGTCGGACAACCTGCCCGACGACGCGGCCACCGATGTCGTCCA
GGCACTCCGGCGTGCCACCACGTTCCAGATGCCGATCCTGATCATCGCTCACCACGCGTCCCAGGTGAATCTGATCGACG
CTTTCGACGCCGGTGCGGACGACTATGTCATGTTCGCCAGCGACCCGAACAGCCTGTTGCCACGGATCATCGGCCACCAT
CGGCGCGCCCGCCGGCGCGGAGGATCGGGCGGCAGGCAGCTCAGTGCAGGCGACTACACGCTTGACCTCGATGCCTGCTG
CGTGAGGTTCCGCGCAGAGACCATCCGTCTGACGCCCAAGGAGTTTGCGCTGGCCAAGCTGATGTTCTCTTCCCCCGCCG
TGACCTTGCCACGTGATCACATCGAGATCGTCGTCTGGGGCAGCACCCTGCCACCGCTATCGCGCGCGCTGGCTGCCATG
GTAGCCCGGCTTCGACGCGTGCTTCGGCTCCGCCCGGAGCACGGCGTGACACTGCGGGGCGTGCATTCGATGGGCTACCG
GCTCGATATCGCCGCTCCTGAGTCCAGAGTCTAG

Upstream 100 bases:

>100_bases
CTCGCGCTCGCGCTGCAGCGCTGAGAGCCTGGTCCGACGCCTGCCGAACGCCCGCGATCCGCGTGCGCATCACTTGCTCC
CAAGTACTCAACCCATTCCG

Downstream 100 bases:

>100_bases
AGAACCATGCCCGCCCTGCGGGCATGGCACCATCCCGCACCAGGGCATGCTCGCGAGCGCCCAAGCGAACATGCAAAAGG
CCGTTACCCGATATGGGTAA

Product: winged helix family two component transcriptional regulator (receiver domain)

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 277; Mature: 277

Protein sequence:

>277_residues
MDHSFHRKFPNRPAEWLCYSQSIQHECAPIAGAPGFRKLKVNSIKIALLDAEPSSATGISKVLEAGGVVSSRFTSSERLF
RELRRSVFDVVLVSDNLPDDAATDVVQALRRATTFQMPILIIAHHASQVNLIDAFDAGADDYVMFASDPNSLLPRIIGHH
RRARRRGGSGGRQLSAGDYTLDLDACCVRFRAETIRLTPKEFALAKLMFSSPAVTLPRDHIEIVVWGSTLPPLSRALAAM
VARLRRVLRLRPEHGVTLRGVHSMGYRLDIAAPESRV

Sequences:

>Translated_277_residues
MDHSFHRKFPNRPAEWLCYSQSIQHECAPIAGAPGFRKLKVNSIKIALLDAEPSSATGISKVLEAGGVVSSRFTSSERLF
RELRRSVFDVVLVSDNLPDDAATDVVQALRRATTFQMPILIIAHHASQVNLIDAFDAGADDYVMFASDPNSLLPRIIGHH
RRARRRGGSGGRQLSAGDYTLDLDACCVRFRAETIRLTPKEFALAKLMFSSPAVTLPRDHIEIVVWGSTLPPLSRALAAM
VARLRRVLRLRPEHGVTLRGVHSMGYRLDIAAPESRV
>Mature_277_residues
MDHSFHRKFPNRPAEWLCYSQSIQHECAPIAGAPGFRKLKVNSIKIALLDAEPSSATGISKVLEAGGVVSSRFTSSERLF
RELRRSVFDVVLVSDNLPDDAATDVVQALRRATTFQMPILIIAHHASQVNLIDAFDAGADDYVMFASDPNSLLPRIIGHH
RRARRRGGSGGRQLSAGDYTLDLDACCVRFRAETIRLTPKEFALAKLMFSSPAVTLPRDHIEIVVWGSTLPPLSRALAAM
VARLRRVLRLRPEHGVTLRGVHSMGYRLDIAAPESRV

Specific function: The N-terminus of this protein is required for the transcriptional expression of both major outer membrane protein genes ompF and ompC; its C-terminal moiety mediates the multimerization of the ompR protein. As a multimer, it turns on the expression of th

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1789809, Length=229, Percent_Identity=25.764192139738, Blast_Score=75, Evalue=3e-15,
Organism=Escherichia coli, GI1786784, Length=231, Percent_Identity=26.8398268398268, Blast_Score=65, Evalue=6e-12,
Organism=Escherichia coli, GI2367329, Length=177, Percent_Identity=26.5536723163842, Blast_Score=63, Evalue=2e-11,
Organism=Escherichia coli, GI1789402, Length=225, Percent_Identity=25.7777777777778, Blast_Score=61, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 30613; Mature: 30613

Theoretical pI: Translated: 10.26; Mature: 10.26

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDHSFHRKFPNRPAEWLCYSQSIQHECAPIAGAPGFRKLKVNSIKIALLDAEPSSATGIS
CCCCCCCCCCCCCHHHEEHHHHHHHHCCCCCCCCCCEEEEECEEEEEEEECCCCCCHHHH
KVLEAGGVVSSRFTSSERLFRELRRSVFDVVLVSDNLPDDAATDVVQALRRATTFQMPIL
HHHHHCCCHHHHCCCHHHHHHHHHHHHHEEEEEECCCCCHHHHHHHHHHHHHHHHCCCEE
IIAHHASQVNLIDAFDAGADDYVMFASDPNSLLPRIIGHHRRARRRGGSGGRQLSAGDYT
EEEECCCCEEEEECCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHCCCCCCCEECCCCEE
LDLDACCVRFRAETIRLTPKEFALAKLMFSSPAVTLPRDHIEIVVWGSTLPPLSRALAAM
EEHHHHHHHHHHHHEEECHHHHHHHHHHHCCCCCCCCCCCEEEEEECCCCCHHHHHHHHH
VARLRRVLRLRPEHGVTLRGVHSMGYRLDIAAPESRV
HHHHHHHHHCCCCCCCEEEEECCCCEEEEECCCCCCC
>Mature Secondary Structure
MDHSFHRKFPNRPAEWLCYSQSIQHECAPIAGAPGFRKLKVNSIKIALLDAEPSSATGIS
CCCCCCCCCCCCCHHHEEHHHHHHHHCCCCCCCCCCEEEEECEEEEEEEECCCCCCHHHH
KVLEAGGVVSSRFTSSERLFRELRRSVFDVVLVSDNLPDDAATDVVQALRRATTFQMPIL
HHHHHCCCHHHHCCCHHHHHHHHHHHHHEEEEEECCCCCHHHHHHHHHHHHHHHHCCCEE
IIAHHASQVNLIDAFDAGADDYVMFASDPNSLLPRIIGHHRRARRRGGSGGRQLSAGDYT
EEEECCCCEEEEECCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHCCCCCCCEECCCCEE
LDLDACCVRFRAETIRLTPKEFALAKLMFSSPAVTLPRDHIEIVVWGSTLPPLSRALAAM
EEHHHHHHHHHHHHEEECHHHHHHHHHHHCCCCCCCCCCCEEEEEECCCCCHHHHHHHHH
VARLRRVLRLRPEHGVTLRGVHSMGYRLDIAAPESRV
HHHHHHHHHCCCCCCCEEEEECCCCEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]