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The map label for this gene is yegD [H]

Identifier: 94314576

GI number: 94314576

Start: 2415564

End: 2416817

Strand: Direct

Name: yegD [H]

Synonym: Rmet_5657

Alternate gene names: 94314576

Gene position: 2415564-2416817 (Clockwise)

Preceding gene: 94314574

Following gene: 94314581

Centisome position: 93.62

GC content: 65.95

Gene sequence:

>1254_bases
ATGATCGCAAACGCATGTGGTGTCGACTTCGGCACGTCCAACTCGACCGTGGGCTGGGTTCGCCCGGGCGCATCGACGCT
CCTGCCGCTCGAGGACGACAAGGCGACCCTGCCCTCCGTGATCTTCTTCCATGCGGAAGACCCGCTGGTCAGCTATGGCC
GCGCGGCACTGGCCGACTATCTGGCCGGCTACGAGGGGCGCATGATGCGTTCGCTCAAGAGCCTGCTGGGCACGTCGATG
ATGGATGACAGCACCGAAGTAATGGGCCAGGCCATGCCTTTCCGCAAGCTGCTGGCGCACTTCATCGGCGAACTCAAGGG
CCGCGCCGAACGCGCCGCCGGCCGCGAGTTTACGTCGGCCGTACTGGGCCGACCGGTGCATTTCATCGACGAGGATGCCG
CCGCCGACCAGCTTGCCGAGGACACGCTGGCCGAGATCGCCCGCGACGCGGGCTTCCGCGATATCGCGTTCCAGTACGAG
CCAATTGCCGCAGCCTTCGACTACGAAGCCGGCATCGGCGGTGAAGAACTCGTGCTGGTGGCCGACATCGGCGGCGGCAC
GTCCGACTTCTCGCTCGTTCGCCTGTCCCCGGAGCGCGCCCGCCACATCGACCGCCGCGACGACATCCTCGCCAATGGCG
GCGTGCATATCGGCGGGACCGATTTCGACCGCGCTCTGAGCCTCGCCAGTGTGATGCCGATGCTGGGCCTGGGCAGTCAG
CTTCGCAACGGCAAGGCCATGCCTTCGGGCCAGTACTTCGACCTGGCGAGCTGGCACACCATCAACCTGGTTTACACACG
CAAGGCCTGGTCGATCGTGATGGACAACTATCGCGATACCGCCGACACCGTGAAGCTTGATCGCCTGATCCGGCTGATCC
GCGAGCGCGCGGGCCACTGGCTGGCAATCCAGGTGGAAGCCGCCAAGATCGCGCTGTCCGCGGAAGCGCAGACCGTGGTC
GACTTGGACCGTATCGCGCCCGACACCACACTCGCCATCACCCGCGAGACCTTCGACGAGTCCATCGCCAAACTGGTCGA
CAAGACCGCCACGACGGTGCACGGCATGCTCAAGACGGCTGGCGTCAAGGCCGAGGCCGTCGACACGATCCTGTTCACCG
GGGGTTCCAGCAGCGTACCGCTGCTGCGCGAGCAACTCGCGCAATTGCTGCCGGGCGCGCGCCGCGTGGAAGGTGATCTG
TTCGGCGGTATCGGTTCGGGACTCGCGCTGGACGCGCTGCGCAAGTTCGGCTGA

Upstream 100 bases:

>100_bases
ATTCATACCCGCCGCAAGGAAAACCAATACAATAGCGCCCCGCGCGGCGGACGCCCCTGGCTCCGCCTCTCCTTGCACCT
CTGCCCTCATCCGGAATTTC

Downstream 100 bases:

>100_bases
GCGCGCAGCCGCCGCGCACTGGTATCAGGGCAGCCGTTCGCTGCCCACTTCCTGCATCGACGTCTGTTCGTGCGCGTGGT
GCACGCGATTGCGACCGCTG

Product: putative chaperone protein (yegD); putative heat shock protein Hsp70 class

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 417; Mature: 417

Protein sequence:

>417_residues
MIANACGVDFGTSNSTVGWVRPGASTLLPLEDDKATLPSVIFFHAEDPLVSYGRAALADYLAGYEGRMMRSLKSLLGTSM
MDDSTEVMGQAMPFRKLLAHFIGELKGRAERAAGREFTSAVLGRPVHFIDEDAAADQLAEDTLAEIARDAGFRDIAFQYE
PIAAAFDYEAGIGGEELVLVADIGGGTSDFSLVRLSPERARHIDRRDDILANGGVHIGGTDFDRALSLASVMPMLGLGSQ
LRNGKAMPSGQYFDLASWHTINLVYTRKAWSIVMDNYRDTADTVKLDRLIRLIRERAGHWLAIQVEAAKIALSAEAQTVV
DLDRIAPDTTLAITRETFDESIAKLVDKTATTVHGMLKTAGVKAEAVDTILFTGGSSSVPLLREQLAQLLPGARRVEGDL
FGGIGSGLALDALRKFG

Sequences:

>Translated_417_residues
MIANACGVDFGTSNSTVGWVRPGASTLLPLEDDKATLPSVIFFHAEDPLVSYGRAALADYLAGYEGRMMRSLKSLLGTSM
MDDSTEVMGQAMPFRKLLAHFIGELKGRAERAAGREFTSAVLGRPVHFIDEDAAADQLAEDTLAEIARDAGFRDIAFQYE
PIAAAFDYEAGIGGEELVLVADIGGGTSDFSLVRLSPERARHIDRRDDILANGGVHIGGTDFDRALSLASVMPMLGLGSQ
LRNGKAMPSGQYFDLASWHTINLVYTRKAWSIVMDNYRDTADTVKLDRLIRLIRERAGHWLAIQVEAAKIALSAEAQTVV
DLDRIAPDTTLAITRETFDESIAKLVDKTATTVHGMLKTAGVKAEAVDTILFTGGSSSVPLLREQLAQLLPGARRVEGDL
FGGIGSGLALDALRKFG
>Mature_417_residues
MIANACGVDFGTSNSTVGWVRPGASTLLPLEDDKATLPSVIFFHAEDPLVSYGRAALADYLAGYEGRMMRSLKSLLGTSM
MDDSTEVMGQAMPFRKLLAHFIGELKGRAERAAGREFTSAVLGRPVHFIDEDAAADQLAEDTLAEIARDAGFRDIAFQYE
PIAAAFDYEAGIGGEELVLVADIGGGTSDFSLVRLSPERARHIDRRDDILANGGVHIGGTDFDRALSLASVMPMLGLGSQ
LRNGKAMPSGQYFDLASWHTINLVYTRKAWSIVMDNYRDTADTVKLDRLIRLIRERAGHWLAIQVEAAKIALSAEAQTVV
DLDRIAPDTTLAITRETFDESIAKLVDKTATTVHGMLKTAGVKAEAVDTILFTGGSSSVPLLREQLAQLLPGARRVEGDL
FGGIGSGLALDALRKFG

Specific function: Unknown

COG id: COG0443

COG function: function code O; Molecular chaperone

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the heat shock protein 70 family [H]

Homologues:

Organism=Homo sapiens, GI124256496, Length=417, Percent_Identity=24.9400479616307, Blast_Score=72, Evalue=1e-12,
Organism=Escherichia coli, GI87082035, Length=448, Percent_Identity=31.0267857142857, Blast_Score=197, Evalue=1e-51,
Organism=Escherichia coli, GI1788875, Length=432, Percent_Identity=28.2407407407407, Blast_Score=95, Evalue=1e-20,
Organism=Escherichia coli, GI1786196, Length=421, Percent_Identity=25.1781472684086, Blast_Score=85, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI17534015, Length=419, Percent_Identity=26.491646778043, Blast_Score=85, Evalue=8e-17,
Organism=Caenorhabditis elegans, GI17534013, Length=419, Percent_Identity=26.491646778043, Blast_Score=85, Evalue=8e-17,
Organism=Caenorhabditis elegans, GI17507981, Length=418, Percent_Identity=24.6411483253589, Blast_Score=79, Evalue=3e-15,
Organism=Drosophila melanogaster, GI24641406, Length=433, Percent_Identity=25.635103926097, Blast_Score=71, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24641408, Length=433, Percent_Identity=25.635103926097, Blast_Score=71, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24641402, Length=433, Percent_Identity=25.635103926097, Blast_Score=71, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24641404, Length=433, Percent_Identity=25.635103926097, Blast_Score=71, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018181
- InterPro:   IPR001023
- InterPro:   IPR013126 [H]

Pfam domain/function: PF00012 HSP70 [H]

EC number: NA

Molecular weight: Translated: 44905; Mature: 44905

Theoretical pI: Translated: 4.91; Mature: 4.91

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIANACGVDFGTSNSTVGWVRPGASTLLPLEDDKATLPSVIFFHAEDPLVSYGRAALADY
CCCCCCCCCCCCCCCEEEEECCCCCEEEECCCCCCCCCEEEEEECCCCHHHHHHHHHHHH
LAGYEGRMMRSLKSLLGTSMMDDSTEVMGQAMPFRKLLAHFIGELKGRAERAAGREFTSA
HCCCCHHHHHHHHHHHCCHHCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCHHHHHH
VLGRPVHFIDEDAAADQLAEDTLAEIARDAGFRDIAFQYEPIAAAFDYEAGIGGEELVLV
HHCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCEEECCCCCCCCCEEEEE
ADIGGGTSDFSLVRLSPERARHIDRRDDILANGGVHIGGTDFDRALSLASVMPMLGLGSQ
EECCCCCCCCEEEEECHHHHHCCCHHHCEEECCCEEECCCCHHHHHHHHHHHHHHCCCHH
LRNGKAMPSGQYFDLASWHTINLVYTRKAWSIVMDNYRDTADTVKLDRLIRLIRERAGHW
HCCCCCCCCCCEEECCCCEEEEEEEECCHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCE
LAIQVEAAKIALSAEAQTVVDLDRIAPDTTLAITRETFDESIAKLVDKTATTVHGMLKTA
EEEEEEEEEEEEECCCHHHHHHHHCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHC
GVKAEAVDTILFTGGSSSVPLLREQLAQLLPGARRVEGDLFGGIGSGLALDALRKFG
CCCHHHEEEEEEECCCCCCHHHHHHHHHHCCCCEEECCHHCCCCCCHHHHHHHHHCC
>Mature Secondary Structure
MIANACGVDFGTSNSTVGWVRPGASTLLPLEDDKATLPSVIFFHAEDPLVSYGRAALADY
CCCCCCCCCCCCCCCEEEEECCCCCEEEECCCCCCCCCEEEEEECCCCHHHHHHHHHHHH
LAGYEGRMMRSLKSLLGTSMMDDSTEVMGQAMPFRKLLAHFIGELKGRAERAAGREFTSA
HCCCCHHHHHHHHHHHCCHHCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCHHHHHH
VLGRPVHFIDEDAAADQLAEDTLAEIARDAGFRDIAFQYEPIAAAFDYEAGIGGEELVLV
HHCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCEEECCCCCCCCCEEEEE
ADIGGGTSDFSLVRLSPERARHIDRRDDILANGGVHIGGTDFDRALSLASVMPMLGLGSQ
EECCCCCCCCEEEEECHHHHHCCCHHHCEEECCCEEECCCCHHHHHHHHHHHHHHCCCHH
LRNGKAMPSGQYFDLASWHTINLVYTRKAWSIVMDNYRDTADTVKLDRLIRLIRERAGHW
HCCCCCCCCCCEEECCCCEEEEEEEECCHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCE
LAIQVEAAKIALSAEAQTVVDLDRIAPDTTLAITRETFDESIAKLVDKTATTVHGMLKTA
EEEEEEEEEEEEECCCHHHHHHHHCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHC
GVKAEAVDTILFTGGSSSVPLLREQLAQLLPGARRVEGDLFGGIGSGLALDALRKFG
CCCHHHEEEEEEECCCCCCHHHHHHHHHHCCCCEEECCHHCCCCCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9097040; 9278503; 6094528; 7940673; 7984428 [H]