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The map label for this gene is cyoB [H]

Identifier: 94314528

GI number: 94314528

Start: 2365055

End: 2367058

Strand: Direct

Name: cyoB [H]

Synonym: Rmet_5609

Alternate gene names: 94314528

Gene position: 2365055-2367058 (Clockwise)

Preceding gene: 94314527

Following gene: 94314529

Centisome position: 91.67

GC content: 61.83

Gene sequence:

>2004_bases
ATGCCCGAGCGCTCCGAACTCGCCAACCTGATTTTCGGCCGACTGTCATGGGAGGCCATTCCCTACCATGAGCCGATCCT
GATCGCCACCTTCGCCGCCGTGGCGATAGGCGGACTGGCACTGGTGGCGCTGCTGACGTACTTCCGCGCGTGGGGCTATC
TCTGGCGAGAGTGGTTCACCAGCATCGACCACAAGAAGATCGGCATCATGTACATCGTGCTGGGCATCGTGATGCTGCTG
CGTGGCTTTGCCGATGCGGTCATGATGCGGATGCAGCAGGCCGTCGCGTTCGGCGACAACGCCGGGTTTCTGCCACCTCA
CCACTACGACCAGATCTTCACCGCGCACGGCGTGATCATGATCTTCTTCGTGGCCATGCCGCTGGTCACCGGGCTGATGA
ACTTTGTCATGCCGTTGCAGATCGGCGCGCGCGACGTGGCATTCCCGTTCCTCAACAACTTCAGCTTCTGGATGACCACG
GGCGGCGCGATTCTGGTCATGATGTCGCTGTTCGTAGGCGAATTCGCGCGCACCGGCTGGCTGGCCTATCCTCCGCTTTC
GGGCATCCTCCACAGTCCCGACGTTGGCGTGGATTACTACATATGGGCGCTACAGATAGCGGGGGTGGGGACGCTGTTAT
CAGGGATCAACCTGCTGGTCACCATCGTCAAGATGCGCGCCCCTGGCATGACGCTAATGCGGATGCCGATCTTCACGTGG
ACGTCGCTGTGCACGAACGTGCTGATCATCGCCGCCTTCCCGGTACTGACCGCCGCGCTGGCGCTGCTGGCGCTGGATCG
CTACGCCGGCACGAACTTCTTCACAGCCGACCAGGGCGGCAGCGCGATGATGTACGTGAACCTGATCTGGATCTGGGGTC
ACCCCGAGGTCTACATCCTGGTATTGCCGGTGTTCGGTGTGTTCTCGGAAGTGGTGGCCACGTTCGCGCGCAAGCGCCTG
TTCGGCTACGCGTCGATGGTCTATGCGACGGTGGTGATCACCGTGCTCTCCTACCTGGTCTGGCTGCACCACTTCTTCAC
GATGGGCTCCGGCGCCAGCGTCAATTCGTTCTTCGGGATCACGACGATGATCATCTCGATCCCGACCGGCGCCAAGATCT
TCAACTGGCTGTTCACGATGTACCACGGCAAGATCCGCTTCGAGCCACCGATGCTGTGGACGGTCGGCTTTATGGTCACG
TTCGTGATCGGCGGCATGACCGGCGTGCTGCTGGCAGTGCCTCCGGCGGACTTCTCGCTACACAACAGCCTGTTCCTGAT
CGCCCACTTCCATAACGTAATCATCGGCGGCGTGCTGTTCGGGCTGATGGCCGGCATCACGTACTGGTTCCCCAAGGCAT
TCGGCTATCGCCTGGTGTCGTCGTGGGGCAAGGCGTCGTTCTGGTTCTGGTTCGTCGGCTTCTACTTCGCGTTCATGCCG
CTGTACTGGCTCGGCCTGCTCGGCGTGACCCGCCGCATGAACCATTTTGACGATCCGTCGCTGCAGATCTGGTTCCAGAT
CGCCGCGTTCGGCGCGTTGCTGATCGCCATCGGCATCGCCTGCTTCCTGATCCAGCTCGTGGTGAGCTTCATGCGCCGCG
AGGAACTCCGCGACACCACCGGCGACCCCTGGGGCGGCCGCACGCTCGAATGGTCGACCTCGTCGCCGCCGCCGCAGTAC
AACTTCGCATTCACGCCGGTCGTGCACGACACCGATGCCTGGTGGCACATGAAACACAACGGCTTCCAGCGGCCGCAGCA
AGGCTTCATCCCGATCCACATGCCGAAGGGCACGGCGGCCGGCATCGTACTGGCCGGGCTCTCCACGATATGCGGCTTCG
CGTTGATCTGGCACATCTGGTGGTTGGTCATCGCGTCGTTCGCGGCCACGATCATTGCAGCGATCATCCATACCTTCAAC
TACAAGCGCGACTACTACATTTCGGCAGAGCAGGTGGTCCGGACTGAAGCGGCGCGCACCCAACTGATGGCCGGCCATGG
TTGA

Upstream 100 bases:

>100_bases
TAGACGACTGCTGCGGTGAAGCGGGGATTCGCCCCCATTTTTCCGGTTCCCGCCAATCATCATCGGTCAATTTTGGCCAA
CACAGGCCCAGGTGACAAAC

Downstream 100 bases:

>100_bases
CACGACCCTACCCCTGCACGCGCACGGCACGGCCGATGCGGACCAAGCGCCCCCCGGCGGCTATCAGTTCTACCTGACCG
AGGAGGTACATCCTCAGAAC

Product: cytochrome o ubiquinol oxidase subunit I

Products: NA

Alternate protein names: Cytochrome o subunit 1; Cytochrome o ubiquinol oxidase subunit 1; Oxidase BO(3) subunit 1; Ubiquinol oxidase chain A; Ubiquinol oxidase polypeptide I [H]

Number of amino acids: Translated: 667; Mature: 666

Protein sequence:

>667_residues
MPERSELANLIFGRLSWEAIPYHEPILIATFAAVAIGGLALVALLTYFRAWGYLWREWFTSIDHKKIGIMYIVLGIVMLL
RGFADAVMMRMQQAVAFGDNAGFLPPHHYDQIFTAHGVIMIFFVAMPLVTGLMNFVMPLQIGARDVAFPFLNNFSFWMTT
GGAILVMMSLFVGEFARTGWLAYPPLSGILHSPDVGVDYYIWALQIAGVGTLLSGINLLVTIVKMRAPGMTLMRMPIFTW
TSLCTNVLIIAAFPVLTAALALLALDRYAGTNFFTADQGGSAMMYVNLIWIWGHPEVYILVLPVFGVFSEVVATFARKRL
FGYASMVYATVVITVLSYLVWLHHFFTMGSGASVNSFFGITTMIISIPTGAKIFNWLFTMYHGKIRFEPPMLWTVGFMVT
FVIGGMTGVLLAVPPADFSLHNSLFLIAHFHNVIIGGVLFGLMAGITYWFPKAFGYRLVSSWGKASFWFWFVGFYFAFMP
LYWLGLLGVTRRMNHFDDPSLQIWFQIAAFGALLIAIGIACFLIQLVVSFMRREELRDTTGDPWGGRTLEWSTSSPPPQY
NFAFTPVVHDTDAWWHMKHNGFQRPQQGFIPIHMPKGTAAGIVLAGLSTICGFALIWHIWWLVIASFAATIIAAIIHTFN
YKRDYYISAEQVVRTEAARTQLMAGHG

Sequences:

>Translated_667_residues
MPERSELANLIFGRLSWEAIPYHEPILIATFAAVAIGGLALVALLTYFRAWGYLWREWFTSIDHKKIGIMYIVLGIVMLL
RGFADAVMMRMQQAVAFGDNAGFLPPHHYDQIFTAHGVIMIFFVAMPLVTGLMNFVMPLQIGARDVAFPFLNNFSFWMTT
GGAILVMMSLFVGEFARTGWLAYPPLSGILHSPDVGVDYYIWALQIAGVGTLLSGINLLVTIVKMRAPGMTLMRMPIFTW
TSLCTNVLIIAAFPVLTAALALLALDRYAGTNFFTADQGGSAMMYVNLIWIWGHPEVYILVLPVFGVFSEVVATFARKRL
FGYASMVYATVVITVLSYLVWLHHFFTMGSGASVNSFFGITTMIISIPTGAKIFNWLFTMYHGKIRFEPPMLWTVGFMVT
FVIGGMTGVLLAVPPADFSLHNSLFLIAHFHNVIIGGVLFGLMAGITYWFPKAFGYRLVSSWGKASFWFWFVGFYFAFMP
LYWLGLLGVTRRMNHFDDPSLQIWFQIAAFGALLIAIGIACFLIQLVVSFMRREELRDTTGDPWGGRTLEWSTSSPPPQY
NFAFTPVVHDTDAWWHMKHNGFQRPQQGFIPIHMPKGTAAGIVLAGLSTICGFALIWHIWWLVIASFAATIIAAIIHTFN
YKRDYYISAEQVVRTEAARTQLMAGHG
>Mature_666_residues
PERSELANLIFGRLSWEAIPYHEPILIATFAAVAIGGLALVALLTYFRAWGYLWREWFTSIDHKKIGIMYIVLGIVMLLR
GFADAVMMRMQQAVAFGDNAGFLPPHHYDQIFTAHGVIMIFFVAMPLVTGLMNFVMPLQIGARDVAFPFLNNFSFWMTTG
GAILVMMSLFVGEFARTGWLAYPPLSGILHSPDVGVDYYIWALQIAGVGTLLSGINLLVTIVKMRAPGMTLMRMPIFTWT
SLCTNVLIIAAFPVLTAALALLALDRYAGTNFFTADQGGSAMMYVNLIWIWGHPEVYILVLPVFGVFSEVVATFARKRLF
GYASMVYATVVITVLSYLVWLHHFFTMGSGASVNSFFGITTMIISIPTGAKIFNWLFTMYHGKIRFEPPMLWTVGFMVTF
VIGGMTGVLLAVPPADFSLHNSLFLIAHFHNVIIGGVLFGLMAGITYWFPKAFGYRLVSSWGKASFWFWFVGFYFAFMPL
YWLGLLGVTRRMNHFDDPSLQIWFQIAAFGALLIAIGIACFLIQLVVSFMRREELRDTTGDPWGGRTLEWSTSSPPPQYN
FAFTPVVHDTDAWWHMKHNGFQRPQQGFIPIHMPKGTAAGIVLAGLSTICGFALIWHIWWLVIASFAATIIAAIIHTFNY
KRDYYISAEQVVRTEAARTQLMAGHG

Specific function: Cytochrome o terminal oxidase complex is the component of the aerobic respiratory chain that predominates when cells are grown at high aeration. This ubiquinol oxidase shows proton pump activity across the membrane in addition to the electron transfer [H]

COG id: COG0843

COG function: function code C; Heme/copper-type cytochrome/quinol oxidases, subunit 1

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the heme-copper respiratory oxidase family [H]

Homologues:

Organism=Homo sapiens, GI251831109, Length=512, Percent_Identity=37.6953125, Blast_Score=325, Evalue=6e-89,
Organism=Escherichia coli, GI1786634, Length=648, Percent_Identity=68.0555555555556, Blast_Score=921, Evalue=0.0,
Organism=Saccharomyces cerevisiae, GI6226519, Length=535, Percent_Identity=35.8878504672897, Blast_Score=329, Evalue=7e-91,
Organism=Saccharomyces cerevisiae, GI6226524, Length=325, Percent_Identity=40.9230769230769, Blast_Score=239, Evalue=1e-63,
Organism=Saccharomyces cerevisiae, GI6226523, Length=253, Percent_Identity=34.7826086956522, Blast_Score=137, Evalue=5e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000883
- InterPro:   IPR014207 [H]

Pfam domain/function: PF00115 COX1 [H]

EC number: 1.10.3.-

Molecular weight: Translated: 74720; Mature: 74589

Theoretical pI: Translated: 9.03; Mature: 9.03

Prosite motif: PS50855 COX1 ; PS00077 COX1_CUB

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
4.9 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
4.8 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHCCCC
>Mature Secondary Structure 
PERSELANLIFGRLSWEAIPYHEPILIATFAAVAIGGLALVALLTYFRAWGYLWREWFT
CCHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SIDHKKIGIMYIVLGIVMLLRGFADAVMMRMQQAVAFGDNAGFLPPHHYDQIFTAHGVIM
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHH
IFFVAMPLVTGLMNFVMPLQIGARDVAFPFLNNFSFWMTTGGAILVMMSLFVGEFARTGW
HHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCEEEEECCHHHHHHHHHHHHHHHHCCC
LAYPPLSGILHSPDVGVDYYIWALQIAGVGTLLSGINLLVTIVKMRAPGMTLMRMPIFTW
EECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHH
TSLCTNVLIIAAFPVLTAALALLALDRYAGTNFFTADQGGSAMMYVNLIWIWGHPEVYIL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCEEEEEEEEEEECCCCEEEE
VLPVFGVFSEVVATFARKRLFGYASMVYATVVITVLSYLVWLHHFFTMGSGASVNSFFGI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHH
TTMIISIPTGAKIFNWLFTMYHGKIRFEPPMLWTVGFMVTFVIGGMTGVLLAVPPADFSL
HHHEEECCCCHHHHHHHHHHHCCEEEECCCHHHHHHHHHHHHHHHHHCEEEEECCCCCCC
HNSLFLIAHFHNVIIGGVLFGLMAGITYWFPKAFGYRLVSSWGKASFWFWFVGFYFAFMP
CCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
LYWLGLLGVTRRMNHFDDPSLQIWFQIAAFGALLIAIGIACFLIQLVVSFMRREELRDTT
HHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
GDPWGGRTLEWSTSSPPPQYNFAFTPVVHDTDAWWHMKHNGFQRPQQGFIPIHMPKGTAA
CCCCCCCEEECCCCCCCCCCCEEECCEEECCCCEEEECCCCCCCCCCCCEEEECCCCCHH
GIVLAGLSTICGFALIWHIWWLVIASFAATIIAAIIHTFNYKRDYYISAEQVVRTEAART
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECHHHHHHHHHHHH
QLMAGHG
HHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: Protoheme IX (Heme B55 and B562); Copper B. [C]

Metal ions: Fe; Cu [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Oxidoreductases [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]