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The map label for this gene is yciR [C]

Identifier: 94314522

GI number: 94314522

Start: 2357595

End: 2359364

Strand: Direct

Name: yciR [C]

Synonym: Rmet_5603

Alternate gene names: 94314522

Gene position: 2357595-2359364 (Clockwise)

Preceding gene: 94314519

Following gene: 94314523

Centisome position: 91.38

GC content: 65.82

Gene sequence:

>1770_bases
ATGACCGCGTTCGCATTCGATGTTGCTCTGGCACCGGAGCCTGCCGATCGCAGGCGGCCCGATGCCGGCCCTGCCTACGG
CGAGGCCCTGGCGTTGCTGGAGGCTTCCGGCGCGCTGGCCATGCGCGTGGACATGCAGGGACGCATTCTCGAAGCGACTG
AAGCCACCGCCGAACTACTGGTCTATCCGCGCGAATACCTGCTGCGCACCTCGATCCTCGACATCATCGCGCTGGAGTCC
CGCGAACGCGTGGCCATGCTGCTGACGTGCTGCGCGCAGGACCAGACCATGCGCCGCGAGCGCGTGCGCGTGGCCGGCGG
TATCGGCGGGCCCAACTGGCTCGACCTGCGCGTGAGCTACCACCGCGATGCCGACGATGCGCCCAGCCTGCTGCTGTTCG
GCCAAGACATCACGCATTGGGTGGAGTCGGAGCGAGACCTGACCGAGCGTGCCTTCCTGGACCCGTTGACCGGTGTCGGC
AACCGCGCCTACATCGGCAAGCGGATCGAGGAATACACGTCCGGCCGCCGCGCGGGCCAGCCGTTCGCGGTTGCCCTGAT
GGATCTGGACGGCTTCAAGAACGTCAACGACTCGCTCGGCCACGAGTTTGGCGACGCGCTGCTCAAGGAAGTGGGCACAC
GCCTGCAGGACACTGTCCGCACGCGCCAAAGCGTGGCGCGGCTGGGTGGCGACGAGTTCGTGCTGATGCTCGATGACATG
GAGTCCGAGGCGGACGCCATCCGCATCCTCGAGCGCGTGATCCATGTCTGCCGCCAGCCCTTCCTGCTGGGCGGCTGCCA
GGTGCGCATCACCACCAGCATCGGCCTGGCCTTCTCGAACGGTTCGGCGCAATCGGAGTCGCAATGGCTGCGCCGTGCGG
ACCTGGCGATGTACGAGGCGAAGGCGCTCGGCAAGAACCGTTACTGCATCTACTCGCCCGAACTCGACCGCCGCCTGGAC
GAACAGTTCCAGATCGAGCAGAGCATGTTCGAAGCGGTGCAGAACGGAGAATTCCTGCTGCACTACCAGCCGATCGTCTG
GCCCGGAAGCGGTGAAGTCTGCGCCGTGGAAGCACTGATGCGCTGGGAGCACGCAGGCCGCGATATCCGGCCCGATGTGT
TCATTCCCGTCGCCGAGAAGAACGGTCTGATCAAACACCTTGGCGCGTGGGCGCTGCGCTGCGCCTGCGCGCAGCTTGCC
GCCTGGGATGCGCTGGGTATCCATGTAGGCCATATGTCGGTCAACGTGTCAGCCGTGCAGTTCCTGCATCCGGGCTTCTT
CGACAGCGTCCGCAATGCGATCCAGGAATCGGGCATCGGCGCCGACCGGCTACTGCTGGAAATCACCGAAAGCGCGCTGA
TGACCGATCCGAAGGCCGCCGAGGAACTGCTCCTTTCGCTGCGTGCGCTCGGCATCCGCTTCGCCGTCGATGATTTCGGC
ACCGGCTATTCGAGCCTGTCGTACCTGCGCCGCTTTCCGCTGTCGGCCCTTAAGGTCGACCGCAGCTTCGTCGCCGACAT
GGTCGATTCACCGCACGCGCGGACCATCGTGTCGGCCGTGCTGTCGCTGGCACGCGAACTCGGTCTCGTCGCCATTGCCG
AGGGCGTGGAAACCGATGCCCAAAACAAGCTGTTGGCCGCGCAGGGCTGCAACCTTGTGCAGGGATGGCGCTTTGCACGT
GCCGTCGCCGCCGCCGATTTCGAGAGCGCCGTCACCGACGGCAGGTTCGTGGTCGGCGAGGGCGAAGTCTTCGCGCCACG
GGTGTCCTGA

Upstream 100 bases:

>100_bases
TAGCCACGGACTGGCGTTGCCGCGGGTATCCAACCCTACAGATCACAAGAAACCAACCGATATCAGCCATGCGCCCATTG
GGCTCAGGGTTGAAAGATAC

Downstream 100 bases:

>100_bases
TGTCCAAGTCCGATTTCTTCGAGACCCTGTGGGCACGGATGGCGCAACAGGGAGACTTCCCGACGCTTCAGTACTGTGTC
GACAACATCTTCAAGACGCT

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 589; Mature: 588

Protein sequence:

>589_residues
MTAFAFDVALAPEPADRRRPDAGPAYGEALALLEASGALAMRVDMQGRILEATEATAELLVYPREYLLRTSILDIIALES
RERVAMLLTCCAQDQTMRRERVRVAGGIGGPNWLDLRVSYHRDADDAPSLLLFGQDITHWVESERDLTERAFLDPLTGVG
NRAYIGKRIEEYTSGRRAGQPFAVALMDLDGFKNVNDSLGHEFGDALLKEVGTRLQDTVRTRQSVARLGGDEFVLMLDDM
ESEADAIRILERVIHVCRQPFLLGGCQVRITTSIGLAFSNGSAQSESQWLRRADLAMYEAKALGKNRYCIYSPELDRRLD
EQFQIEQSMFEAVQNGEFLLHYQPIVWPGSGEVCAVEALMRWEHAGRDIRPDVFIPVAEKNGLIKHLGAWALRCACAQLA
AWDALGIHVGHMSVNVSAVQFLHPGFFDSVRNAIQESGIGADRLLLEITESALMTDPKAAEELLLSLRALGIRFAVDDFG
TGYSSLSYLRRFPLSALKVDRSFVADMVDSPHARTIVSAVLSLARELGLVAIAEGVETDAQNKLLAAQGCNLVQGWRFAR
AVAAADFESAVTDGRFVVGEGEVFAPRVS

Sequences:

>Translated_589_residues
MTAFAFDVALAPEPADRRRPDAGPAYGEALALLEASGALAMRVDMQGRILEATEATAELLVYPREYLLRTSILDIIALES
RERVAMLLTCCAQDQTMRRERVRVAGGIGGPNWLDLRVSYHRDADDAPSLLLFGQDITHWVESERDLTERAFLDPLTGVG
NRAYIGKRIEEYTSGRRAGQPFAVALMDLDGFKNVNDSLGHEFGDALLKEVGTRLQDTVRTRQSVARLGGDEFVLMLDDM
ESEADAIRILERVIHVCRQPFLLGGCQVRITTSIGLAFSNGSAQSESQWLRRADLAMYEAKALGKNRYCIYSPELDRRLD
EQFQIEQSMFEAVQNGEFLLHYQPIVWPGSGEVCAVEALMRWEHAGRDIRPDVFIPVAEKNGLIKHLGAWALRCACAQLA
AWDALGIHVGHMSVNVSAVQFLHPGFFDSVRNAIQESGIGADRLLLEITESALMTDPKAAEELLLSLRALGIRFAVDDFG
TGYSSLSYLRRFPLSALKVDRSFVADMVDSPHARTIVSAVLSLARELGLVAIAEGVETDAQNKLLAAQGCNLVQGWRFAR
AVAAADFESAVTDGRFVVGEGEVFAPRVS
>Mature_588_residues
TAFAFDVALAPEPADRRRPDAGPAYGEALALLEASGALAMRVDMQGRILEATEATAELLVYPREYLLRTSILDIIALESR
ERVAMLLTCCAQDQTMRRERVRVAGGIGGPNWLDLRVSYHRDADDAPSLLLFGQDITHWVESERDLTERAFLDPLTGVGN
RAYIGKRIEEYTSGRRAGQPFAVALMDLDGFKNVNDSLGHEFGDALLKEVGTRLQDTVRTRQSVARLGGDEFVLMLDDME
SEADAIRILERVIHVCRQPFLLGGCQVRITTSIGLAFSNGSAQSESQWLRRADLAMYEAKALGKNRYCIYSPELDRRLDE
QFQIEQSMFEAVQNGEFLLHYQPIVWPGSGEVCAVEALMRWEHAGRDIRPDVFIPVAEKNGLIKHLGAWALRCACAQLAA
WDALGIHVGHMSVNVSAVQFLHPGFFDSVRNAIQESGIGADRLLLEITESALMTDPKAAEELLLSLRALGIRFAVDDFGT
GYSSLSYLRRFPLSALKVDRSFVADMVDSPHARTIVSAVLSLARELGLVAIAEGVETDAQNKLLAAQGCNLVQGWRFARA
VAAADFESAVTDGRFVVGEGEVFAPRVS

Specific function: Unknown

COG id: COG5001

COG function: function code T; Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 MHYT domain [H]

Homologues:

Organism=Escherichia coli, GI1787541, Length=444, Percent_Identity=36.036036036036, Blast_Score=269, Evalue=4e-73,
Organism=Escherichia coli, GI87081921, Length=428, Percent_Identity=31.3084112149533, Blast_Score=225, Evalue=6e-60,
Organism=Escherichia coli, GI226510982, Length=432, Percent_Identity=29.6296296296296, Blast_Score=189, Evalue=4e-49,
Organism=Escherichia coli, GI87081743, Length=239, Percent_Identity=33.0543933054393, Blast_Score=138, Evalue=9e-34,
Organism=Escherichia coli, GI1786507, Length=239, Percent_Identity=35.5648535564854, Blast_Score=137, Evalue=1e-33,
Organism=Escherichia coli, GI87081845, Length=255, Percent_Identity=35.2941176470588, Blast_Score=135, Evalue=5e-33,
Organism=Escherichia coli, GI1790496, Length=238, Percent_Identity=32.3529411764706, Blast_Score=133, Evalue=3e-32,
Organism=Escherichia coli, GI1788502, Length=246, Percent_Identity=32.1138211382114, Blast_Score=126, Evalue=3e-30,
Organism=Escherichia coli, GI1787055, Length=253, Percent_Identity=32.0158102766798, Blast_Score=114, Evalue=1e-26,
Organism=Escherichia coli, GI87081980, Length=235, Percent_Identity=33.6170212765957, Blast_Score=108, Evalue=7e-25,
Organism=Escherichia coli, GI1788849, Length=432, Percent_Identity=23.6111111111111, Blast_Score=103, Evalue=4e-23,
Organism=Escherichia coli, GI1786584, Length=182, Percent_Identity=34.0659340659341, Blast_Score=97, Evalue=3e-21,
Organism=Escherichia coli, GI1788381, Length=194, Percent_Identity=34.5360824742268, Blast_Score=95, Evalue=1e-20,
Organism=Escherichia coli, GI1788956, Length=187, Percent_Identity=35.2941176470588, Blast_Score=95, Evalue=1e-20,
Organism=Escherichia coli, GI87082096, Length=455, Percent_Identity=24.6153846153846, Blast_Score=94, Evalue=2e-20,
Organism=Escherichia coli, GI145693134, Length=168, Percent_Identity=35.7142857142857, Blast_Score=94, Evalue=3e-20,
Organism=Escherichia coli, GI1787262, Length=157, Percent_Identity=35.6687898089172, Blast_Score=89, Evalue=5e-19,
Organism=Escherichia coli, GI87081977, Length=176, Percent_Identity=30.1136363636364, Blast_Score=80, Evalue=4e-16,
Organism=Escherichia coli, GI87081881, Length=184, Percent_Identity=33.1521739130435, Blast_Score=77, Evalue=3e-15,
Organism=Escherichia coli, GI1787816, Length=174, Percent_Identity=32.7586206896552, Blast_Score=75, Evalue=8e-15,
Organism=Escherichia coli, GI1788085, Length=164, Percent_Identity=34.1463414634146, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI1787802, Length=168, Percent_Identity=29.1666666666667, Blast_Score=70, Evalue=5e-13,
Organism=Escherichia coli, GI1787410, Length=230, Percent_Identity=26.5217391304348, Blast_Score=69, Evalue=1e-12,
Organism=Escherichia coli, GI87082007, Length=168, Percent_Identity=29.1666666666667, Blast_Score=69, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR000160
- InterPro:   IPR001633
- InterPro:   IPR005330 [H]

Pfam domain/function: PF00563 EAL; PF00990 GGDEF; PF03707 MHYT [H]

EC number: NA

Molecular weight: Translated: 64847; Mature: 64715

Theoretical pI: Translated: 4.86; Mature: 4.86

Prosite motif: PS50883 EAL ; PS50887 GGDEF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTAFAFDVALAPEPADRRRPDAGPAYGEALALLEASGALAMRVDMQGRILEATEATAELL
CCEEEEEEEECCCCCCCCCCCCCCCHHHHHHHHCCCCCEEEEECCCCCEEHHHHHHHHHH
VYPREYLLRTSILDIIALESRERVAMLLTCCAQDQTMRRERVRVAGGIGGPNWLDLRVSY
HCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCEEEEEEEE
HRDADDAPSLLLFGQDITHWVESERDLTERAFLDPLTGVGNRAYIGKRIEEYTSGRRAGQ
CCCCCCCCCEEEECCHHHHHHHHHHHHHHHHHHCHHHCCCCHHHHHHHHHHHHCCCCCCC
PFAVALMDLDGFKNVNDSLGHEFGDALLKEVGTRLQDTVRTRQSVARLGGDEFVLMLDDM
CEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECC
ESEADAIRILERVIHVCRQPFLLGGCQVRITTSIGLAFSNGSAQSESQWLRRADLAMYEA
CCHHHHHHHHHHHHHHHCCCCEECCCEEEEEEEEEEEECCCCCCHHHHHHHHHHHHHHHH
KALGKNRYCIYSPELDRRLDEQFQIEQSMFEAVQNGEFLLHYQPIVWPGSGEVCAVEALM
HHCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHCCCCEEEEEECEEECCCCCHHHHHHHH
RWEHAGRDIRPDVFIPVAEKNGLIKHLGAWALRCACAQLAAWDALGIHVGHMSVNVSAVQ
HHHHCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHEEEEEEEEEEHHHHH
FLHPGFFDSVRNAIQESGIGADRLLLEITESALMTDPKAAEELLLSLRALGIRFAVDDFG
HHCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHEEEECCCC
TGYSSLSYLRRFPLSALKVDRSFVADMVDSPHARTIVSAVLSLARELGLVAIAEGVETDA
CCHHHHHHHHHCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCEEECCCCCCCC
QNKLLAAQGCNLVQGWRFARAVAAADFESAVTDGRFVVGEGEVFAPRVS
CCCEEHHCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCEECCCCC
>Mature Secondary Structure 
TAFAFDVALAPEPADRRRPDAGPAYGEALALLEASGALAMRVDMQGRILEATEATAELL
CEEEEEEEECCCCCCCCCCCCCCCHHHHHHHHCCCCCEEEEECCCCCEEHHHHHHHHHH
VYPREYLLRTSILDIIALESRERVAMLLTCCAQDQTMRRERVRVAGGIGGPNWLDLRVSY
HCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCEEEEEEEE
HRDADDAPSLLLFGQDITHWVESERDLTERAFLDPLTGVGNRAYIGKRIEEYTSGRRAGQ
CCCCCCCCCEEEECCHHHHHHHHHHHHHHHHHHCHHHCCCCHHHHHHHHHHHHCCCCCCC
PFAVALMDLDGFKNVNDSLGHEFGDALLKEVGTRLQDTVRTRQSVARLGGDEFVLMLDDM
CEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECC
ESEADAIRILERVIHVCRQPFLLGGCQVRITTSIGLAFSNGSAQSESQWLRRADLAMYEA
CCHHHHHHHHHHHHHHHCCCCEECCCEEEEEEEEEEEECCCCCCHHHHHHHHHHHHHHHH
KALGKNRYCIYSPELDRRLDEQFQIEQSMFEAVQNGEFLLHYQPIVWPGSGEVCAVEALM
HHCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHCCCCEEEEEECEEECCCCCHHHHHHHH
RWEHAGRDIRPDVFIPVAEKNGLIKHLGAWALRCACAQLAAWDALGIHVGHMSVNVSAVQ
HHHHCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHEEEEEEEEEEHHHHH
FLHPGFFDSVRNAIQESGIGADRLLLEITESALMTDPKAAEELLLSLRALGIRFAVDDFG
HHCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHEEEECCCC
TGYSSLSYLRRFPLSALKVDRSFVADMVDSPHARTIVSAVLSLARELGLVAIAEGVETDA
CCHHHHHHHHHCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCEEECCCCCCCC
QNKLLAAQGCNLVQGWRFARAVAAADFESAVTDGRFVVGEGEVFAPRVS
CCCEEHHCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]