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The map label for this gene is katA [H]

Identifier: 94314518

GI number: 94314518

Start: 2353057

End: 2354502

Strand: Direct

Name: katA [H]

Synonym: Rmet_5599

Alternate gene names: 94314518

Gene position: 2353057-2354502 (Clockwise)

Preceding gene: 94314515

Following gene: 94314519

Centisome position: 91.2

GC content: 62.17

Gene sequence:

>1446_bases
ATGAATAAGCTCACGACCGCATTTGGCGCGCCCGTTGTCGATAACCAGAACGTTCAGACCGCCGGCCCGCGTGGCCCCGC
CCTGCTCCAGGATGTCTGGTTCCTCGAAAAGCTTGCCCACTTCGACCGTGAAGTGATTCCGGAACGCCGCATGCACGCCA
AGGGCGCCGGCGCTTACGGCACGTTCACGGTCACGCATGACATCACCAAGTACACGCGCGCGAACCTGTTCTCACAGGTT
GGCAAGAAAACCGACCTGTTCCTGCGCTTCTCGTCGGTGGCCGGCGAGCGCGGCGCGGCCGATGCGGAACGCGACATCCG
CGGCTTTGCGATCAAGTTCTACACCGAGGAAGGCAACTGGGACCTGGTGGGCAACAACACCCCGGTTTTCTTCCTGCGCG
ACCCCCTGAAGTTCCCCGACCTGAACCACGCCGTGAAGCGCGACCCGCGCACGGGCATGCGTAGCGCCGAAAGCAACTGG
GACTTCTGGACCGGCCTGCCCGAAGCCCTGCACCAGGTCACGATCGTGATGAGTGACCGGGGTATCCCGCGCACCTGGCG
TCATATGCACGGGTTCGGCAGCCATACCTACAGCTTCATCAACGCCAACATGGAGCGTTTCTGGGTGAAGTTCCACTTCG
TCACCCAGCAGGGCATCCAGAACCTGACTGACGAGGAAGCTGCGGAGATCACGGGCCAGGACCGCGAATATCACCAGCGC
GATCTGTTTGAATCAATCGAACGTGGCGATTTCCCGCGCTGGAAGCTCTGCGTGCAGATCATGCCGGAAGCCGAAGCCAG
CAAGGTTCCCTACCACCCGTTCGACCTGACCAAAATCTGGCCGAAGAAGGACTACCCGCTGATCGAAGTCGGCGTGCTGG
AACTGAACCGCAATCCGGACAACTTCTTCGCCGAAGTCGAACAGGCATCGTTCGCGCCGTCGACGATCGTCCCTGGCGTC
GGTTTCTCGCCCGACAAGATGTTGCAGGGCCGTCTATTCTCGTACGGCGACGCCGCGCGCTATCGCGTCGGCGTGAATCA
TCACCAGATTCCGGTGAACTCGCCGAAAGCCGCGAAGTACGTCAACAGCTATCACCGCGACGGCACGATGCGCGTCGACG
GCAACCGGGGGGCCGCCATCGGCTATGAGCCCAATACGAAGGGCGAGTGGGCCGAGCAACCCGACTTCCGCGAACCGCCG
CTGACGCTGGAAGGCACTGCCGACCACTGGAACCATCGCGAGGACGGCGACTACTTCTCGCAGGTCGGCGCGTTGTTCCG
CCTGATGTCGCCGACGCAGCAGCAGGCGCTGTTCGACAACACGGCCCGCTCGATCAAGGGTGTGTCGAAACACATCCAGC
AGACCCACATCAAGCATTGCACGGCGGCTGACCCCGCCTATGGTGCGGGTGTCGCGGCTGCTATCGAGATGATCGAGGCC
AAGTAA

Upstream 100 bases:

>100_bases
CCGGCGCCCTCGGTGACGCGGCCACGAGCCGCGGCAATTCCGTCCCACAAATGTCCAGACGCGACCCTTCCGGATCGCAC
GACTGCATCAAGGAATGACT

Downstream 100 bases:

>100_bases
GTCCCCACTACCCATGCCTCTCCCGCCCCCGGGAGAGGCATGGGCGGAACGACTCAGCAAATCCCGAACAAACCGTCCGA
GACAGGAAAATGATGATGGA

Product: catalase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 481; Mature: 481

Protein sequence:

>481_residues
MNKLTTAFGAPVVDNQNVQTAGPRGPALLQDVWFLEKLAHFDREVIPERRMHAKGAGAYGTFTVTHDITKYTRANLFSQV
GKKTDLFLRFSSVAGERGAADAERDIRGFAIKFYTEEGNWDLVGNNTPVFFLRDPLKFPDLNHAVKRDPRTGMRSAESNW
DFWTGLPEALHQVTIVMSDRGIPRTWRHMHGFGSHTYSFINANMERFWVKFHFVTQQGIQNLTDEEAAEITGQDREYHQR
DLFESIERGDFPRWKLCVQIMPEAEASKVPYHPFDLTKIWPKKDYPLIEVGVLELNRNPDNFFAEVEQASFAPSTIVPGV
GFSPDKMLQGRLFSYGDAARYRVGVNHHQIPVNSPKAAKYVNSYHRDGTMRVDGNRGAAIGYEPNTKGEWAEQPDFREPP
LTLEGTADHWNHREDGDYFSQVGALFRLMSPTQQQALFDNTARSIKGVSKHIQQTHIKHCTAADPAYGAGVAAAIEMIEA
K

Sequences:

>Translated_481_residues
MNKLTTAFGAPVVDNQNVQTAGPRGPALLQDVWFLEKLAHFDREVIPERRMHAKGAGAYGTFTVTHDITKYTRANLFSQV
GKKTDLFLRFSSVAGERGAADAERDIRGFAIKFYTEEGNWDLVGNNTPVFFLRDPLKFPDLNHAVKRDPRTGMRSAESNW
DFWTGLPEALHQVTIVMSDRGIPRTWRHMHGFGSHTYSFINANMERFWVKFHFVTQQGIQNLTDEEAAEITGQDREYHQR
DLFESIERGDFPRWKLCVQIMPEAEASKVPYHPFDLTKIWPKKDYPLIEVGVLELNRNPDNFFAEVEQASFAPSTIVPGV
GFSPDKMLQGRLFSYGDAARYRVGVNHHQIPVNSPKAAKYVNSYHRDGTMRVDGNRGAAIGYEPNTKGEWAEQPDFREPP
LTLEGTADHWNHREDGDYFSQVGALFRLMSPTQQQALFDNTARSIKGVSKHIQQTHIKHCTAADPAYGAGVAAAIEMIEA
K
>Mature_481_residues
MNKLTTAFGAPVVDNQNVQTAGPRGPALLQDVWFLEKLAHFDREVIPERRMHAKGAGAYGTFTVTHDITKYTRANLFSQV
GKKTDLFLRFSSVAGERGAADAERDIRGFAIKFYTEEGNWDLVGNNTPVFFLRDPLKFPDLNHAVKRDPRTGMRSAESNW
DFWTGLPEALHQVTIVMSDRGIPRTWRHMHGFGSHTYSFINANMERFWVKFHFVTQQGIQNLTDEEAAEITGQDREYHQR
DLFESIERGDFPRWKLCVQIMPEAEASKVPYHPFDLTKIWPKKDYPLIEVGVLELNRNPDNFFAEVEQASFAPSTIVPGV
GFSPDKMLQGRLFSYGDAARYRVGVNHHQIPVNSPKAAKYVNSYHRDGTMRVDGNRGAAIGYEPNTKGEWAEQPDFREPP
LTLEGTADHWNHREDGDYFSQVGALFRLMSPTQQQALFDNTARSIKGVSKHIQQTHIKHCTAADPAYGAGVAAAIEMIEA
K

Specific function: Decomposes hydrogen peroxide into water and oxygen; serves to protect cells from the toxic effects of hydrogen peroxide. Could protect cells in nodules which have a high potential to produce hydrogen peroxide because of the strong reducing conditions requ

COG id: COG0753

COG function: function code P; Catalase

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the catalase family [H]

Homologues:

Organism=Homo sapiens, GI4557014, Length=479, Percent_Identity=51.1482254697286, Blast_Score=499, Evalue=1e-141,
Organism=Escherichia coli, GI48994891, Length=487, Percent_Identity=41.4784394250513, Blast_Score=356, Evalue=2e-99,
Organism=Caenorhabditis elegans, GI71998444, Length=473, Percent_Identity=48.6257928118393, Blast_Score=474, Evalue=1e-134,
Organism=Caenorhabditis elegans, GI25147792, Length=468, Percent_Identity=47.4358974358974, Blast_Score=456, Evalue=1e-128,
Organism=Caenorhabditis elegans, GI25151141, Length=468, Percent_Identity=47.2222222222222, Blast_Score=454, Evalue=1e-128,
Organism=Saccharomyces cerevisiae, GI6320462, Length=488, Percent_Identity=46.9262295081967, Blast_Score=415, Evalue=1e-117,
Organism=Saccharomyces cerevisiae, GI6321525, Length=411, Percent_Identity=39.6593673965937, Blast_Score=309, Evalue=6e-85,
Organism=Drosophila melanogaster, GI17981717, Length=480, Percent_Identity=46.875, Blast_Score=449, Evalue=1e-126,
Organism=Drosophila melanogaster, GI19920968, Length=476, Percent_Identity=44.9579831932773, Blast_Score=433, Evalue=1e-121,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002226
- InterPro:   IPR020835
- InterPro:   IPR010582
- InterPro:   IPR018028
- InterPro:   IPR011614 [H]

Pfam domain/function: PF00199 Catalase; PF06628 Catalase-rel [H]

EC number: =1.11.1.6 [H]

Molecular weight: Translated: 54459; Mature: 54459

Theoretical pI: Translated: 6.94; Mature: 6.94

Prosite motif: PS00438 CATALASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKLTTAFGAPVVDNQNVQTAGPRGPALLQDVWFLEKLAHFDREVIPERRMHAKGAGAYG
CCCCCCHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCCCCE
TFTVTHDITKYTRANLFSQVGKKTDLFLRFSSVAGERGAADAERDIRGFAIKFYTEEGNW
EEEEEHHHHHHHHHHHHHHHCCCCEEEEEEHHHCCCCCCCCHHHCCCEEEEEEEEECCCE
DLVGNNTPVFFLRDPLKFPDLNHAVKRDPRTGMRSAESNWDFWTGLPEALHQVTIVMSDR
EEECCCCCEEEEECCCCCCCCCHHHHCCCCCCCCCCCCCCCHHCCHHHHHHEEEEEEECC
GIPRTWRHMHGFGSHTYSFINANMERFWVKFHFVTQQGIQNLTDEEAAEITGQDREYHQR
CCCHHHHHHHCCCCHHHHHHHCCCEEEEEEEEEEHHHHHHHCCHHHHHHHCCCCHHHHHH
DLFESIERGDFPRWKLCVQIMPEAEASKVPYHPFDLTKIWPKKDYPLIEVGVLELNRNPD
HHHHHHHHCCCCHHEEHEEECCCCCCCCCCCCCCCCCEECCCCCCCEEEEEEEEECCCCH
NFFAEVEQASFAPSTIVPGVGFSPDKMLQGRLFSYGDAARYRVGVNHHQIPVNSPKAAKY
HHHHHHHHHCCCCCCCCCCCCCCHHHHHHCHHHCCCCCCEEEECCCCCCCCCCCCHHHHH
VNSYHRDGTMRVDGNRGAAIGYEPNTKGEWAEQPDFREPPLTLEGTADHWNHREDGDYFS
HHHHCCCCCEEECCCCCEEECCCCCCCCCCCCCCCCCCCCEEEECCHHCCCCCCCCHHHH
QVGALFRLMSPTQQQALFDNTARSIKGVSKHIQQTHIKHCTAADPAYGAGVAAAIEMIEA
HHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHC
K
C
>Mature Secondary Structure
MNKLTTAFGAPVVDNQNVQTAGPRGPALLQDVWFLEKLAHFDREVIPERRMHAKGAGAYG
CCCCCCHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCCCCE
TFTVTHDITKYTRANLFSQVGKKTDLFLRFSSVAGERGAADAERDIRGFAIKFYTEEGNW
EEEEEHHHHHHHHHHHHHHHCCCCEEEEEEHHHCCCCCCCCHHHCCCEEEEEEEEECCCE
DLVGNNTPVFFLRDPLKFPDLNHAVKRDPRTGMRSAESNWDFWTGLPEALHQVTIVMSDR
EEECCCCCEEEEECCCCCCCCCHHHHCCCCCCCCCCCCCCCHHCCHHHHHHEEEEEEECC
GIPRTWRHMHGFGSHTYSFINANMERFWVKFHFVTQQGIQNLTDEEAAEITGQDREYHQR
CCCHHHHHHHCCCCHHHHHHHCCCEEEEEEEEEEHHHHHHHCCHHHHHHHCCCCHHHHHH
DLFESIERGDFPRWKLCVQIMPEAEASKVPYHPFDLTKIWPKKDYPLIEVGVLELNRNPD
HHHHHHHHCCCCHHEEHEEECCCCCCCCCCCCCCCCCEECCCCCCCEEEEEEEEECCCCH
NFFAEVEQASFAPSTIVPGVGFSPDKMLQGRLFSYGDAARYRVGVNHHQIPVNSPKAAKY
HHHHHHHHHCCCCCCCCCCCCCCHHHHHHCHHHCCCCCCEEEECCCCCCCCCCCCHHHHH
VNSYHRDGTMRVDGNRGAAIGYEPNTKGEWAEQPDFREPPLTLEGTADHWNHREDGDYFS
HHHHCCCCCEEECCCCCEEECCCCCCCCCCCCCCCCCCCCEEEECCHHCCCCCCCCHHHH
QVGALFRLMSPTQQQALFDNTARSIKGVSKHIQQTHIKHCTAADPAYGAGVAAAIEMIEA
HHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHC
K
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9555890 [H]