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The map label for this gene is 94314459

Identifier: 94314459

GI number: 94314459

Start: 2285908

End: 2287002

Strand: Reverse

Name: 94314459

Synonym: Rmet_5540

Alternate gene names: NA

Gene position: 2287002-2285908 (Counterclockwise)

Preceding gene: 94314460

Following gene: 94314458

Centisome position: 88.64

GC content: 57.9

Gene sequence:

>1095_bases
ATGACCCGCCTTGTCGTGGATGCCGTGAAAGATGCGGGGGTCGACAAGCAGGATATTCAAAGTCTGGTGTTCACGCTCCC
TCGTCCATACACGCGCCAGAAGTACTTTCACACTTTCCTCATGGGCCAACTTCGGCTGTCTTGCCGGGGCAACGTGATGG
AAGTGATGGGTAACGGCATGACTGCTGCTCTGGCTTTCGACCAGGCCTGCAATGACATCATGCTGGGCAGGTCTGAGGTG
TCGCTTGCTCTCGGTATCAACATGGAGAGCGCGGTATCGGCCGCAGAACACATGATGAGCAGCATGCGGACGACCGGCGA
TGTCGACTTTCACACATCAGCTGGCTTCACGCCCATCGCTTGGTATGCCATGGACGCGATGCGGTATATGCATGAGCACG
GAGCTACGAGGGAGGAACTGTGCTCCGTTGCCGTGAAGAACCGTTTTCACGCCTCCATGAATCCGCTTGCGCAGTATCGC
AAGCCGGTGACGCTGGAAGAAGTCGTTCAGCAGCGTCCCATCGTCGAGCCGCTGGGACTCTATGACGTTCCGCCGCGTGG
CGATGGTGCAGCGTGTCTGGTTCTGGCAAGTGAGGATGTCGCACGCGAGCTTGGCCGCCCATATGTGCTCGTAAAGGGCC
GAGGATTCTTCCATGATGGCAGCCATCAGATCAGTGATGTCCCCAACGACATGATTGCATTCGAGTCGGCGAGACAGGCG
GCTTCTGTCGCCTATGAACAAGCTGGCATCAGCGCCAAGGACGTCGACGTCGCTGAGTTGTATGCGCCTTGCACGATTGT
CGAAGTGCTGGTGAGTGAGGCTATTGGACTTATTCCGAAGGGGCATGGTGCGCGCGCGGCATTCAATGGAGAGACACGTC
TCGGCGGCCATATTCCTATCTCGACCTCAGGTGGTTTGACATCCCGCGGCCACCCTGCGTACGTCACCTCGCTCTACAAC
TACGTGGAGCTCGCTGAGCAACTGCGGGGACGGGCAGGCGAGCGCCAAGTCAAGAATGCGCAGTTCGGTCTGGCTACAGG
AGAACTCGGCAACTACAACGCGGCCATGATTCACGTTATGGAGGCCAAGCAATGA

Upstream 100 bases:

>100_bases
CGCGAAAACCGGGGCGATTCATATTGGTGCCAGTGCCATTCCGGTGGGGCGCCACCAAACTGCAGATGATGCAGCGCTCC
AGACATTGGAGCACGAAATC

Downstream 100 bases:

>100_bases
CCCTCGAAGCATTGATTGTCGACGGTGAGCGTGCGTACCCGCCGCGGGAATCCGAATTCACCAAGGAATTCTGGTCGGAG
CTAGCACAGGGCCGCTGGAT

Product: putative Acetyl-CoA C-acyltransferase

Products: CoA; 3-oxoacyl-CoA

Alternate protein names: NA

Number of amino acids: Translated: 364; Mature: 363

Protein sequence:

>364_residues
MTRLVVDAVKDAGVDKQDIQSLVFTLPRPYTRQKYFHTFLMGQLRLSCRGNVMEVMGNGMTAALAFDQACNDIMLGRSEV
SLALGINMESAVSAAEHMMSSMRTTGDVDFHTSAGFTPIAWYAMDAMRYMHEHGATREELCSVAVKNRFHASMNPLAQYR
KPVTLEEVVQQRPIVEPLGLYDVPPRGDGAACLVLASEDVARELGRPYVLVKGRGFFHDGSHQISDVPNDMIAFESARQA
ASVAYEQAGISAKDVDVAELYAPCTIVEVLVSEAIGLIPKGHGARAAFNGETRLGGHIPISTSGGLTSRGHPAYVTSLYN
YVELAEQLRGRAGERQVKNAQFGLATGELGNYNAAMIHVMEAKQ

Sequences:

>Translated_364_residues
MTRLVVDAVKDAGVDKQDIQSLVFTLPRPYTRQKYFHTFLMGQLRLSCRGNVMEVMGNGMTAALAFDQACNDIMLGRSEV
SLALGINMESAVSAAEHMMSSMRTTGDVDFHTSAGFTPIAWYAMDAMRYMHEHGATREELCSVAVKNRFHASMNPLAQYR
KPVTLEEVVQQRPIVEPLGLYDVPPRGDGAACLVLASEDVARELGRPYVLVKGRGFFHDGSHQISDVPNDMIAFESARQA
ASVAYEQAGISAKDVDVAELYAPCTIVEVLVSEAIGLIPKGHGARAAFNGETRLGGHIPISTSGGLTSRGHPAYVTSLYN
YVELAEQLRGRAGERQVKNAQFGLATGELGNYNAAMIHVMEAKQ
>Mature_363_residues
TRLVVDAVKDAGVDKQDIQSLVFTLPRPYTRQKYFHTFLMGQLRLSCRGNVMEVMGNGMTAALAFDQACNDIMLGRSEVS
LALGINMESAVSAAEHMMSSMRTTGDVDFHTSAGFTPIAWYAMDAMRYMHEHGATREELCSVAVKNRFHASMNPLAQYRK
PVTLEEVVQQRPIVEPLGLYDVPPRGDGAACLVLASEDVARELGRPYVLVKGRGFFHDGSHQISDVPNDMIAFESARQAA
SVAYEQAGISAKDVDVAELYAPCTIVEVLVSEAIGLIPKGHGARAAFNGETRLGGHIPISTSGGLTSRGHPAYVTSLYNY
VELAEQLRGRAGERQVKNAQFGLATGELGNYNAAMIHVMEAKQ

Specific function: Unknown

COG id: COG0183

COG function: function code I; Acetyl-CoA acetyltransferase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI302344762, Length=294, Percent_Identity=31.2925170068027, Blast_Score=128, Evalue=1e-29,
Organism=Homo sapiens, GI302344767, Length=307, Percent_Identity=30.2931596091205, Blast_Score=122, Evalue=5e-28,
Organism=Homo sapiens, GI302344760, Length=307, Percent_Identity=30.2931596091205, Blast_Score=122, Evalue=5e-28,
Organism=Homo sapiens, GI19923233, Length=307, Percent_Identity=30.2931596091205, Blast_Score=122, Evalue=6e-28,
Organism=Homo sapiens, GI55956775, Length=262, Percent_Identity=29.3893129770992, Blast_Score=103, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI17537653, Length=223, Percent_Identity=33.6322869955157, Blast_Score=124, Evalue=6e-29,
Organism=Drosophila melanogaster, GI19921506, Length=352, Percent_Identity=28.9772727272727, Blast_Score=113, Evalue=2e-25,
Organism=Drosophila melanogaster, GI24585051, Length=353, Percent_Identity=27.7620396600567, Blast_Score=107, Evalue=9e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002155
- InterPro:   IPR016039
- InterPro:   IPR016038
- InterPro:   IPR020617
- InterPro:   IPR020616 [H]

Pfam domain/function: PF02803 Thiolase_C; PF00108 Thiolase_N [H]

EC number: 2.3.1.16

Molecular weight: Translated: 39587; Mature: 39455

Theoretical pI: Translated: 6.37; Mature: 6.37

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
4.7 %Met     (Translated Protein)
6.0 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
4.4 %Met     (Mature Protein)
5.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTRLVVDAVKDAGVDKQDIQSLVFTLPRPYTRQKYFHTFLMGQLRLSCRGNVMEVMGNGM
CCCHHHHHHHHCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHCCCC
TAALAFDQACNDIMLGRSEVSLALGINMESAVSAAEHMMSSMRTTGDVDFHTSAGFTPIA
EEEHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHH
WYAMDAMRYMHEHGATREELCSVAVKNRFHASMNPLAQYRKPVTLEEVVQQRPIVEPLGL
HHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCHHHHHCCCCCHHHHHHHCCCCCCCCC
YDVPPRGDGAACLVLASEDVARELGRPYVLVKGRGFFHDGSHQISDVPNDMIAFESARQA
CCCCCCCCCCEEEEECCHHHHHHCCCCEEEEECCCCCCCCCCCHHCCCCHHHHHHHHHHH
ASVAYEQAGISAKDVDVAELYAPCTIVEVLVSEAIGLIPKGHGARAAFNGETRLGGHIPI
HHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEECCCCCCCCEEEE
STSGGLTSRGHPAYVTSLYNYVELAEQLRGRAGERQVKNAQFGLATGELGNYNAAMIHVM
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHCCCCCEECCCCCCCCEEEEEEE
EAKQ
ECCC
>Mature Secondary Structure 
TRLVVDAVKDAGVDKQDIQSLVFTLPRPYTRQKYFHTFLMGQLRLSCRGNVMEVMGNGM
CCHHHHHHHHCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHCCCC
TAALAFDQACNDIMLGRSEVSLALGINMESAVSAAEHMMSSMRTTGDVDFHTSAGFTPIA
EEEHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHH
WYAMDAMRYMHEHGATREELCSVAVKNRFHASMNPLAQYRKPVTLEEVVQQRPIVEPLGL
HHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCHHHHHCCCCCHHHHHHHCCCCCCCCC
YDVPPRGDGAACLVLASEDVARELGRPYVLVKGRGFFHDGSHQISDVPNDMIAFESARQA
CCCCCCCCCCEEEEECCHHHHHHCCCCEEEEECCCCCCCCCCCHHCCCCHHHHHHHHHHH
ASVAYEQAGISAKDVDVAELYAPCTIVEVLVSEAIGLIPKGHGARAAFNGETRLGGHIPI
HHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEECCCCCCCCEEEE
STSGGLTSRGHPAYVTSLYNYVELAEQLRGRAGERQVKNAQFGLATGELGNYNAAMIHVM
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHCCCCCEECCCCCCCCEEEEEEE
EAKQ
ECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: acyl-CoA; acetyl-CoA

Specific reaction: acyl-CoA + acetyl-CoA = CoA + 3-oxoacyl-CoA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9371463 [H]