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The map label for this gene is caiD [C]

Identifier: 94314431

GI number: 94314431

Start: 2258086

End: 2258946

Strand: Direct

Name: caiD [C]

Synonym: Rmet_5512

Alternate gene names: 94314431

Gene position: 2258086-2258946 (Clockwise)

Preceding gene: 94314430

Following gene: 94314432

Centisome position: 87.52

GC content: 58.54

Gene sequence:

>861_bases
ATGACTTGGGATAGTTTTACGTTATCGGTGGAAGACCACGTCGCCCACCTTGTGCTGAATCGGCCCGAGAAGCGAAATGC
TTTGTCTCGCGCATTCTGGACTGAATTGCCGCAGGCCGTCCAAGCACTCGATGACGGCGCCCAAGCACGGGTGATCTTAA
TCTCCTCCACGGGGCCGTATTTCAGTAGTGGGATAGATATCGCAATGCTGGGCTCCCTGAGACCTGACATGAAAGGGCCG
GATGCAGAGCGCCGGGCCCGACTTATCGGCCCCTTGACTCGCTATGAGGGCATCGTCGCCTTCCAGCGAAGCTTCAGTTC
TCTCGAGCAGTGCCGGCTGCCGGTGATCGCAGCCGTGCAAGGTGGATGCATCGGTGCTGGACTAGACCTCCTCTCCGCTT
GCTGCATACGATATGCCACCAGTGACGCCTTCTTCTCGGTCTATGAAATCAATGTCGGCATGCCTGCAGATATGGGAACC
TTGCCGCGACTCACCCGCTTCCTGCCGGAGGGTGTGGTACGTGAGCTTGCGTACACCGGGCGCCGAATGGACGCTCGCGA
AGCGCACTTCCGCGGCCTAGTGAATGAAGTCTTCGATGACCATAATTCCCTGTTGGACAAGGCGAAGTCTGTTGCCAGGG
AGATCGCATCGAAGGCACCCATCGCCATCGCCGGCACCAAGCGTCTGATTAACTACGGGCGCGACCACAGCACCGCCGAT
ACGTTAGATCACGTTGCGCTTTGGATAGCGGGCATGAATCCCAGCGAACAAATACTGGACGCCGCCAGGGCGAACGCCGG
GCGAGCCTCCGCAAATTTCGCAGACCTCCCAGTGCGCACGCAGTTCCAAAAGTCGGAATAG

Upstream 100 bases:

>100_bases
GCAGAACTGGCACAGCGATACGGTGAACGGTTTACCCCCCCGGCCCTCCTTCTGGAGAAGGCCGAACGCAACGAACGCTT
CCAGTAACGAAGGATCACCC

Downstream 100 bases:

>100_bases
AAGCCGCATTACGGCATGAAGTAGAGGCACTGACCGACATGAGTAACGCTGAGAGTTTGTCAAAAAGCGCAGAGACGCCG
AGAGACGGCATCCCACTGTG

Product: Enoyl-CoA hydratase/isomerase

Products: NA

Alternate protein names: 3-hydroxypropionyl-CoA dehydratase [H]

Number of amino acids: Translated: 286; Mature: 285

Protein sequence:

>286_residues
MTWDSFTLSVEDHVAHLVLNRPEKRNALSRAFWTELPQAVQALDDGAQARVILISSTGPYFSSGIDIAMLGSLRPDMKGP
DAERRARLIGPLTRYEGIVAFQRSFSSLEQCRLPVIAAVQGGCIGAGLDLLSACCIRYATSDAFFSVYEINVGMPADMGT
LPRLTRFLPEGVVRELAYTGRRMDAREAHFRGLVNEVFDDHNSLLDKAKSVAREIASKAPIAIAGTKRLINYGRDHSTAD
TLDHVALWIAGMNPSEQILDAARANAGRASANFADLPVRTQFQKSE

Sequences:

>Translated_286_residues
MTWDSFTLSVEDHVAHLVLNRPEKRNALSRAFWTELPQAVQALDDGAQARVILISSTGPYFSSGIDIAMLGSLRPDMKGP
DAERRARLIGPLTRYEGIVAFQRSFSSLEQCRLPVIAAVQGGCIGAGLDLLSACCIRYATSDAFFSVYEINVGMPADMGT
LPRLTRFLPEGVVRELAYTGRRMDAREAHFRGLVNEVFDDHNSLLDKAKSVAREIASKAPIAIAGTKRLINYGRDHSTAD
TLDHVALWIAGMNPSEQILDAARANAGRASANFADLPVRTQFQKSE
>Mature_285_residues
TWDSFTLSVEDHVAHLVLNRPEKRNALSRAFWTELPQAVQALDDGAQARVILISSTGPYFSSGIDIAMLGSLRPDMKGPD
AERRARLIGPLTRYEGIVAFQRSFSSLEQCRLPVIAAVQGGCIGAGLDLLSACCIRYATSDAFFSVYEINVGMPADMGTL
PRLTRFLPEGVVRELAYTGRRMDAREAHFRGLVNEVFDDHNSLLDKAKSVAREIASKAPIAIAGTKRLINYGRDHSTADT
LDHVALWIAGMNPSEQILDAARANAGRASANFADLPVRTQFQKSE

Specific function: Plays a role in autotrophic carbon fixation via the 3- hydroxypropionate/4-hydroxybutyrate cycle. Catalyzes the reversible dehydration of 3-hydroxypropionyl-CoA to form acryloyl- CoA, and the reversible dehydration of (S)-3-hydroxybutyryl-CoA to form crot

COG id: COG1024

COG function: function code I; Enoyl-CoA hydratase/carnithine racemase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the enoyl-CoA hydratase/isomerase family [H]

Homologues:

Organism=Homo sapiens, GI70995211, Length=260, Percent_Identity=43.4615384615385, Blast_Score=208, Evalue=4e-54,
Organism=Homo sapiens, GI194097323, Length=228, Percent_Identity=29.3859649122807, Blast_Score=86, Evalue=3e-17,
Organism=Homo sapiens, GI31542718, Length=209, Percent_Identity=31.5789473684211, Blast_Score=81, Evalue=9e-16,
Organism=Homo sapiens, GI4757966, Length=233, Percent_Identity=25.7510729613734, Blast_Score=70, Evalue=3e-12,
Organism=Homo sapiens, GI51538581, Length=233, Percent_Identity=25.7510729613734, Blast_Score=70, Evalue=3e-12,
Organism=Homo sapiens, GI25453481, Length=233, Percent_Identity=25.7510729613734, Blast_Score=70, Evalue=3e-12,
Organism=Homo sapiens, GI51538573, Length=233, Percent_Identity=25.7510729613734, Blast_Score=70, Evalue=3e-12,
Organism=Homo sapiens, GI4757968, Length=202, Percent_Identity=26.7326732673267, Blast_Score=68, Evalue=8e-12,
Organism=Homo sapiens, GI49355787, Length=202, Percent_Identity=26.7326732673267, Blast_Score=68, Evalue=8e-12,
Organism=Homo sapiens, GI4502327, Length=229, Percent_Identity=28.82096069869, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI45643119, Length=200, Percent_Identity=25.5, Blast_Score=66, Evalue=4e-11,
Organism=Homo sapiens, GI260275230, Length=200, Percent_Identity=25.5, Blast_Score=66, Evalue=4e-11,
Organism=Homo sapiens, GI20127408, Length=257, Percent_Identity=26.0700389105058, Blast_Score=66, Evalue=4e-11,
Organism=Homo sapiens, GI260274832, Length=201, Percent_Identity=25.3731343283582, Blast_Score=65, Evalue=5e-11,
Organism=Homo sapiens, GI221136756, Length=223, Percent_Identity=24.6636771300448, Blast_Score=65, Evalue=9e-11,
Organism=Homo sapiens, GI221136753, Length=223, Percent_Identity=24.6636771300448, Blast_Score=65, Evalue=9e-11,
Organism=Escherichia coli, GI221142681, Length=227, Percent_Identity=31.7180616740088, Blast_Score=92, Evalue=5e-20,
Organism=Escherichia coli, GI1788682, Length=215, Percent_Identity=29.3023255813954, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1787659, Length=230, Percent_Identity=26.0869565217391, Blast_Score=79, Evalue=2e-16,
Organism=Escherichia coli, GI87082183, Length=229, Percent_Identity=27.9475982532751, Blast_Score=71, Evalue=6e-14,
Organism=Escherichia coli, GI1790281, Length=206, Percent_Identity=28.1553398058252, Blast_Score=63, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17536985, Length=270, Percent_Identity=36.6666666666667, Blast_Score=183, Evalue=9e-47,
Organism=Caenorhabditis elegans, GI17534483, Length=261, Percent_Identity=33.7164750957854, Blast_Score=175, Evalue=3e-44,
Organism=Caenorhabditis elegans, GI25145438, Length=233, Percent_Identity=28.755364806867, Blast_Score=93, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI17540714, Length=250, Percent_Identity=28, Blast_Score=91, Evalue=9e-19,
Organism=Caenorhabditis elegans, GI17554946, Length=236, Percent_Identity=27.5423728813559, Blast_Score=86, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17560910, Length=245, Percent_Identity=23.6734693877551, Blast_Score=79, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI17558304, Length=210, Percent_Identity=30, Blast_Score=76, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI25144276, Length=215, Percent_Identity=29.7674418604651, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17508953, Length=215, Percent_Identity=29.7674418604651, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17508951, Length=226, Percent_Identity=29.646017699115, Blast_Score=70, Evalue=1e-12,
Organism=Drosophila melanogaster, GI19920382, Length=267, Percent_Identity=40.0749063670412, Blast_Score=184, Evalue=7e-47,
Organism=Drosophila melanogaster, GI24653139, Length=233, Percent_Identity=27.4678111587983, Blast_Score=86, Evalue=4e-17,
Organism=Drosophila melanogaster, GI20129971, Length=231, Percent_Identity=25.5411255411255, Blast_Score=75, Evalue=6e-14,
Organism=Drosophila melanogaster, GI24653477, Length=231, Percent_Identity=25.5411255411255, Blast_Score=75, Evalue=6e-14,
Organism=Drosophila melanogaster, GI21357171, Length=188, Percent_Identity=27.6595744680851, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24650670, Length=212, Percent_Identity=26.8867924528302, Blast_Score=66, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014748
- InterPro:   IPR001753
- InterPro:   IPR018376 [H]

Pfam domain/function: PF00378 ECH [H]

EC number: =4.2.1.116 [H]

Molecular weight: Translated: 31293; Mature: 31162

Theoretical pI: Translated: 7.12; Mature: 7.12

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTWDSFTLSVEDHVAHLVLNRPEKRNALSRAFWTELPQAVQALDDGAQARVILISSTGPY
CCCCCEEEEHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCC
FSSGIDIAMLGSLRPDMKGPDAERRARLIGPLTRYEGIVAFQRSFSSLEQCRLPVIAAVQ
HHCCCCEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEHHC
GGCIGAGLDLLSACCIRYATSDAFFSVYEINVGMPADMGTLPRLTRFLPEGVVRELAYTG
CCCHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHC
RRMDAREAHFRGLVNEVFDDHNSLLDKAKSVAREIASKAPIAIAGTKRLINYGRDHSTAD
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECHHHHHHCCCCCCHHH
TLDHVALWIAGMNPSEQILDAARANAGRASANFADLPVRTQFQKSE
HHHHHHHHEECCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
TWDSFTLSVEDHVAHLVLNRPEKRNALSRAFWTELPQAVQALDDGAQARVILISSTGPY
CCCCEEEEHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCC
FSSGIDIAMLGSLRPDMKGPDAERRARLIGPLTRYEGIVAFQRSFSSLEQCRLPVIAAVQ
HHCCCCEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEHHC
GGCIGAGLDLLSACCIRYATSDAFFSVYEINVGMPADMGTLPRLTRFLPEGVVRELAYTG
CCCHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHC
RRMDAREAHFRGLVNEVFDDHNSLLDKAKSVAREIASKAPIAIAGTKRLINYGRDHSTAD
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECHHHHHHCCCCCCHHH
TLDHVALWIAGMNPSEQILDAARANAGRASANFADLPVRTQFQKSE
HHHHHHHHEECCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA