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The map label for this gene is yngJ [H]

Identifier: 94314356

GI number: 94314356

Start: 2185410

End: 2186573

Strand: Reverse

Name: yngJ [H]

Synonym: Rmet_5437

Alternate gene names: 94314356

Gene position: 2186573-2185410 (Counterclockwise)

Preceding gene: 94314358

Following gene: 94314355

Centisome position: 84.75

GC content: 65.21

Gene sequence:

>1164_bases
ATGTCCCAGACCCGCCGCCTGATCTTCGATGCCGATCACGAGCAGTTCCGTGCTTCGGTCGCGCGTTTCGTGCAGAACGA
AATCACCCCGTATGTGGACCAGTGGCGCGAGCAGGGCTGCTGCGACCGTGCCATCTTCGAGAAAGCCGGCGAGCAGGGCC
TGTTGCTGATGTGGGCCGATGAAGCCTATGGCGGCGCGGGCGTGACCGATTTCCGCTACGAACAGATCCTCTTCGAAGAG
CTGATTCGCCACGGAGATGTCGGCGTGTATCTGACGCTCCATTCGCGGCTGGTCGCGCCATATATTGGCCGGCTGGGCAC
GGAGGCGCAGAAGCGCCGGTGGCTCACCGGCGCGGCCAGCGGCAAGACGATCCTGGCGATTGCCATGACAGAGCCGGGCG
CCGGCTCCGATCTGGCCGGGATCGGCGCACGTGCCGAGCGGCGCGACGGCGGCTGGGTCATCAACGGCGCCAAGACGTTC
ATCTCGAACGGGCACAACGCGGATGCCGTCATCGTGGTCGCGCGTACCAATCCCGACGAGCGACGTGCCTTCGGCCTGTT
CGTCGTCGAGCGCGGCATGGCGGGATTCGAGCGGGGCCGTCGTCTGAAAAAGCTGGGACTGGACGCGCAGGACACGGCGG
AACTGTTCTTCAACGATGTCTTCGTCCCGGACGAGAACGTGCTGGGCAATCCGGCGCGCGGTTTTGCCTATCTGGCGGAG
GGCCTTGAAGAGGAGCGCCTGCTGTGCGCGTGCCAGTCGATCGCGCACGCGCAATCCGCGTTCGATCTGACGCTGCCCTA
CGTCAAGGAGCGCCGCGCATTCGGTCGTCCGATCGGCGCCCTGCAGAACACACGCTTCGTGCTGGCCCGCCGCCGCGCCG
AGCTCGACGCCATGCAGATCTGGCTCGATGCGCTCGTCATGGAGCACAACGCCGGCCGGCTGGATGCCGTCACGGCGGCG
TCTGCCAAGCTGCTGAGCACGGAGTTGGAGAACCGCGTGATCGACGACTGTCTGCAACTGCACGGCGGCTCGGGCTATAT
GGACGAATACCGCATCAGCCGCATGTATCGCGACGCACGCGTATCGCGGATCTTTGCCGGCGCGTCCGAGATCATGCTCG
AGATCATCAGCCGCTCGTTGGGTCTGACGGAGAGAATGGACTAG

Upstream 100 bases:

>100_bases
TCCGGATTTTCCCTAGGGGAGATTCGTCGGATTCGACGAGGCACGGCTGTGGCACCGGTCCTAAGATCGGCCATCGGTCG
TATCCCTTCCTTCCATCACC

Downstream 100 bases:

>100_bases
AGCCCACGGATGGGCCAAGGATGGATCAGGCGGCGACATAGGAGGGACGCTTTGCTAAACTGCCCAGTTCGCGTCCAGCC
CAATCTTCCAGCAAATGACT

Product: Long-chain-acyl-CoA dehydrogenase

Products: 2,3-dehydroacyl-CoA; reduced acceptor

Alternate protein names: NA

Number of amino acids: Translated: 387; Mature: 386

Protein sequence:

>387_residues
MSQTRRLIFDADHEQFRASVARFVQNEITPYVDQWREQGCCDRAIFEKAGEQGLLLMWADEAYGGAGVTDFRYEQILFEE
LIRHGDVGVYLTLHSRLVAPYIGRLGTEAQKRRWLTGAASGKTILAIAMTEPGAGSDLAGIGARAERRDGGWVINGAKTF
ISNGHNADAVIVVARTNPDERRAFGLFVVERGMAGFERGRRLKKLGLDAQDTAELFFNDVFVPDENVLGNPARGFAYLAE
GLEEERLLCACQSIAHAQSAFDLTLPYVKERRAFGRPIGALQNTRFVLARRRAELDAMQIWLDALVMEHNAGRLDAVTAA
SAKLLSTELENRVIDDCLQLHGGSGYMDEYRISRMYRDARVSRIFAGASEIMLEIISRSLGLTERMD

Sequences:

>Translated_387_residues
MSQTRRLIFDADHEQFRASVARFVQNEITPYVDQWREQGCCDRAIFEKAGEQGLLLMWADEAYGGAGVTDFRYEQILFEE
LIRHGDVGVYLTLHSRLVAPYIGRLGTEAQKRRWLTGAASGKTILAIAMTEPGAGSDLAGIGARAERRDGGWVINGAKTF
ISNGHNADAVIVVARTNPDERRAFGLFVVERGMAGFERGRRLKKLGLDAQDTAELFFNDVFVPDENVLGNPARGFAYLAE
GLEEERLLCACQSIAHAQSAFDLTLPYVKERRAFGRPIGALQNTRFVLARRRAELDAMQIWLDALVMEHNAGRLDAVTAA
SAKLLSTELENRVIDDCLQLHGGSGYMDEYRISRMYRDARVSRIFAGASEIMLEIISRSLGLTERMD
>Mature_386_residues
SQTRRLIFDADHEQFRASVARFVQNEITPYVDQWREQGCCDRAIFEKAGEQGLLLMWADEAYGGAGVTDFRYEQILFEEL
IRHGDVGVYLTLHSRLVAPYIGRLGTEAQKRRWLTGAASGKTILAIAMTEPGAGSDLAGIGARAERRDGGWVINGAKTFI
SNGHNADAVIVVARTNPDERRAFGLFVVERGMAGFERGRRLKKLGLDAQDTAELFFNDVFVPDENVLGNPARGFAYLAEG
LEEERLLCACQSIAHAQSAFDLTLPYVKERRAFGRPIGALQNTRFVLARRRAELDAMQIWLDALVMEHNAGRLDAVTAAS
AKLLSTELENRVIDDCLQLHGGSGYMDEYRISRMYRDARVSRIFAGASEIMLEIISRSLGLTERMD

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4501857, Length=378, Percent_Identity=44.1798941798942, Blast_Score=314, Evalue=1e-85,
Organism=Homo sapiens, GI226958412, Length=376, Percent_Identity=33.7765957446808, Blast_Score=206, Evalue=2e-53,
Organism=Homo sapiens, GI226958414, Length=339, Percent_Identity=34.8082595870207, Blast_Score=198, Evalue=8e-51,
Organism=Homo sapiens, GI4501859, Length=380, Percent_Identity=30.7894736842105, Blast_Score=192, Evalue=3e-49,
Organism=Homo sapiens, GI4557233, Length=373, Percent_Identity=32.7077747989276, Blast_Score=186, Evalue=3e-47,
Organism=Homo sapiens, GI187960098, Length=376, Percent_Identity=30.3191489361702, Blast_Score=184, Evalue=8e-47,
Organism=Homo sapiens, GI4557231, Length=376, Percent_Identity=30.3191489361702, Blast_Score=184, Evalue=9e-47,
Organism=Homo sapiens, GI7656849, Length=374, Percent_Identity=28.6096256684492, Blast_Score=176, Evalue=4e-44,
Organism=Homo sapiens, GI76496475, Length=384, Percent_Identity=30.7291666666667, Blast_Score=153, Evalue=2e-37,
Organism=Homo sapiens, GI4557235, Length=384, Percent_Identity=30.7291666666667, Blast_Score=153, Evalue=2e-37,
Organism=Homo sapiens, GI21361497, Length=368, Percent_Identity=29.3478260869565, Blast_Score=147, Evalue=2e-35,
Organism=Homo sapiens, GI211971008, Length=360, Percent_Identity=29.1666666666667, Blast_Score=105, Evalue=6e-23,
Organism=Homo sapiens, GI48976061, Length=360, Percent_Identity=29.1666666666667, Blast_Score=105, Evalue=7e-23,
Organism=Homo sapiens, GI4503943, Length=383, Percent_Identity=27.154046997389, Blast_Score=95, Evalue=1e-19,
Organism=Homo sapiens, GI7669494, Length=357, Percent_Identity=28.0112044817927, Blast_Score=90, Evalue=4e-18,
Organism=Homo sapiens, GI38505218, Length=285, Percent_Identity=25.6140350877193, Blast_Score=84, Evalue=3e-16,
Organism=Escherichia coli, GI87081958, Length=377, Percent_Identity=29.4429708222812, Blast_Score=150, Evalue=2e-37,
Organism=Escherichia coli, GI1786223, Length=279, Percent_Identity=29.7491039426523, Blast_Score=130, Evalue=1e-31,
Organism=Escherichia coli, GI87082384, Length=279, Percent_Identity=28.3154121863799, Blast_Score=74, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17538396, Length=369, Percent_Identity=33.6043360433604, Blast_Score=207, Evalue=6e-54,
Organism=Caenorhabditis elegans, GI17570075, Length=386, Percent_Identity=32.1243523316062, Blast_Score=194, Evalue=9e-50,
Organism=Caenorhabditis elegans, GI17551932, Length=383, Percent_Identity=31.8537859007833, Blast_Score=192, Evalue=3e-49,
Organism=Caenorhabditis elegans, GI17505929, Length=378, Percent_Identity=31.2169312169312, Blast_Score=190, Evalue=1e-48,
Organism=Caenorhabditis elegans, GI17569725, Length=393, Percent_Identity=31.2977099236641, Blast_Score=189, Evalue=3e-48,
Organism=Caenorhabditis elegans, GI17534899, Length=385, Percent_Identity=28.5714285714286, Blast_Score=180, Evalue=1e-45,
Organism=Caenorhabditis elegans, GI17508101, Length=365, Percent_Identity=30.1369863013699, Blast_Score=175, Evalue=3e-44,
Organism=Caenorhabditis elegans, GI17533517, Length=378, Percent_Identity=30.952380952381, Blast_Score=170, Evalue=1e-42,
Organism=Caenorhabditis elegans, GI17506239, Length=371, Percent_Identity=28.8409703504043, Blast_Score=164, Evalue=6e-41,
Organism=Caenorhabditis elegans, GI71985184, Length=340, Percent_Identity=29.4117647058824, Blast_Score=144, Evalue=7e-35,
Organism=Caenorhabditis elegans, GI71990804, Length=272, Percent_Identity=31.6176470588235, Blast_Score=142, Evalue=2e-34,
Organism=Caenorhabditis elegans, GI71982178, Length=270, Percent_Identity=29.6296296296296, Blast_Score=127, Evalue=8e-30,
Organism=Caenorhabditis elegans, GI17534353, Length=374, Percent_Identity=27.807486631016, Blast_Score=120, Evalue=1e-27,
Organism=Caenorhabditis elegans, GI32563615, Length=218, Percent_Identity=32.1100917431193, Blast_Score=114, Evalue=1e-25,
Organism=Caenorhabditis elegans, GI71985192, Length=266, Percent_Identity=27.8195488721804, Blast_Score=105, Evalue=3e-23,
Organism=Caenorhabditis elegans, GI17562446, Length=289, Percent_Identity=28.0276816608997, Blast_Score=80, Evalue=2e-15,
Organism=Drosophila melanogaster, GI21355753, Length=383, Percent_Identity=33.1592689295039, Blast_Score=196, Evalue=2e-50,
Organism=Drosophila melanogaster, GI24660351, Length=374, Percent_Identity=33.4224598930481, Blast_Score=193, Evalue=2e-49,
Organism=Drosophila melanogaster, GI21356377, Length=375, Percent_Identity=30.6666666666667, Blast_Score=182, Evalue=3e-46,
Organism=Drosophila melanogaster, GI24666513, Length=377, Percent_Identity=30.7692307692308, Blast_Score=181, Evalue=1e-45,
Organism=Drosophila melanogaster, GI24646207, Length=372, Percent_Identity=29.5698924731183, Blast_Score=150, Evalue=2e-36,
Organism=Drosophila melanogaster, GI281363737, Length=340, Percent_Identity=29.1176470588235, Blast_Score=133, Evalue=2e-31,
Organism=Drosophila melanogaster, GI19920834, Length=368, Percent_Identity=27.9891304347826, Blast_Score=113, Evalue=2e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: 1.3.99.3

Molecular weight: Translated: 43129; Mature: 42997

Theoretical pI: Translated: 5.97; Mature: 5.97

Prosite motif: PS00072 ACYL_COA_DH_1 ; PS00073 ACYL_COA_DH_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQTRRLIFDADHEQFRASVARFVQNEITPYVDQWREQGCCDRAIFEKAGEQGLLLMWAD
CCCCCCEEEECCHHHHHHHHHHHHHHCCCHHHHHHHHCCCHHHHHHHHCCCCCEEEEEEC
EAYGGAGVTDFRYEQILFEELIRHGDVGVYLTLHSRLVAPYIGRLGTEAQKRRWLTGAAS
CCCCCCCCCHHHHHHHHHHHHHHCCCCEEEEEEHHHHHHHHHHHCCCHHHHHHHHCCCCC
GKTILAIAMTEPGAGSDLAGIGARAERRDGGWVINGAKTFISNGHNADAVIVVARTNPDE
CCEEEEEEEECCCCCCCCHHCCCCCCCCCCCEEEECHHHHHCCCCCCCEEEEEEECCCCH
RRAFGLFVVERGMAGFERGRRLKKLGLDAQDTAELFFNDVFVPDENVLGNPARGFAYLAE
HHHHHHHHHHHCHHHHHHCCHHHHHCCCCHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHC
GLEEERLLCACQSIAHAQSAFDLTLPYVKERRAFGRPIGALQNTRFVLARRRAELDAMQI
CCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCHHHHCCHHHHHHHHHHHHHHHHH
WLDALVMEHNAGRLDAVTAASAKLLSTELENRVIDDCLQLHGGSGYMDEYRISRMYRDAR
HHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHH
VSRIFAGASEIMLEIISRSLGLTERMD
HHHHHHHHHHHHHHHHHHHCCCHHCCC
>Mature Secondary Structure 
SQTRRLIFDADHEQFRASVARFVQNEITPYVDQWREQGCCDRAIFEKAGEQGLLLMWAD
CCCCCEEEECCHHHHHHHHHHHHHHCCCHHHHHHHHCCCHHHHHHHHCCCCCEEEEEEC
EAYGGAGVTDFRYEQILFEELIRHGDVGVYLTLHSRLVAPYIGRLGTEAQKRRWLTGAAS
CCCCCCCCCHHHHHHHHHHHHHHCCCCEEEEEEHHHHHHHHHHHCCCHHHHHHHHCCCCC
GKTILAIAMTEPGAGSDLAGIGARAERRDGGWVINGAKTFISNGHNADAVIVVARTNPDE
CCEEEEEEEECCCCCCCCHHCCCCCCCCCCCEEEECHHHHHCCCCCCCEEEEEEECCCCH
RRAFGLFVVERGMAGFERGRRLKKLGLDAQDTAELFFNDVFVPDENVLGNPARGFAYLAE
HHHHHHHHHHHCHHHHHHCCHHHHHCCCCHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHC
GLEEERLLCACQSIAHAQSAFDLTLPYVKERRAFGRPIGALQNTRFVLARRRAELDAMQI
CCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCHHHHCCHHHHHHHHHHHHHHHHH
WLDALVMEHNAGRLDAVTAASAKLLSTELENRVIDDCLQLHGGSGYMDEYRISRMYRDAR
HHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHH
VSRIFAGASEIMLEIISRSLGLTERMD
HHHHHHHHHHHHHHHHHHHCCCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: acyl-CoA; acceptor

Specific reaction: acyl-CoA + acceptor = 2,3-dehydroacyl-CoA + reduced acceptor

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9387222; 9384377 [H]