Click here to switch to the map view.

The map label for this gene is qseC [H]

Identifier: 94314312

GI number: 94314312

Start: 2118551

End: 2119903

Strand: Direct

Name: qseC [H]

Synonym: Rmet_5393

Alternate gene names: 94314312

Gene position: 2118551-2119903 (Clockwise)

Preceding gene: 94314311

Following gene: 94314313

Centisome position: 82.11

GC content: 66.59

Gene sequence:

>1353_bases
ATGCTGCGCAGCCTGCAGGGCAGACTCTCGGCGGCGCTGGTGGCGGGGCTGGTCGTGCTGGCGTGCGCGGCGGCGGCGGC
ATCGATCCACGTGCTGCGCCAGGAAGTCGATCGTATGTCGGACAGCGCGTTGCAGGAAGCCGCGCAGCGCCTGCTGCCAC
TGGCGCTCACCGAAATCATGCGTCGCGAGGCCGATGACGATGAGGACGACAGCAGCCGCGTCACCGCCGTGCGGCCCCAC
GACGAACTGCTGACCTACGTGGTCCGCGACGACAAGGGCAGTCTGCTGCTGCAGTCGCATGACGCCGATCTCAGTGTTTT
TCCGGCCGGCCTGAAGCCGGGATTCTCCTCCACCCTTTCACATCGGATCTACACCGAACCCGGATTGCAAGGAACGGTAG
CCCTGACGATCGCCGAACCACTTGCCGCCCGGCGGCAAGCAAAAGTCGCGGCCGCGCTCTCGGTCGTCAGGGTTCTGATC
CTGTTTCTTCCCGTCGGCCTGATCGGCATCTGGCTGATCGTCCGGACGGGACTTCAGCCTATCCGCCGGTTCTGCGGCAG
CATCGCCGCGCGCGGCCAGAGCGATCTGACATCGCTTGAAAAGAGCGGACTGCCCACCGAGATCGCGCCGGTGGCTGATG
CGGTCAACGGCCTGATGGCGCGCCTCGATCGCGCGCTGGCTGCCGAGCGCAGCTTCACCGCCAATAGCGCGCACGAACTG
CGCACGCCAATTGCGGCGGCGCTCGCGCAGACGCAGCGTCTCAAAGCCGACATGCCGACCGACGACATGCGGGAGCGCGT
GCAGAACGTCGAACATTCATTGCGCACGCTGGCGCGGCTCAGCGAAAGCCTGATGCAGCTCGCGAAGGCCGAGAACGGGC
GTGTGCTCGGTGACGCGACGCAGGATTTGCGTCCGGTGATTGAACTCGTGATCGAGGACTTCCGGCGCATCGCGCACACG
CCAAACCCGATCACGCTCGACCTGCCCGATCAGCCCGTCGAATCCTGGATCGATCCCGACGCCTTCGCGATCGTGGTGCG
CAATCTGGTCGACAACGCGCAGAAGCACGGCGCACGCGGAGAACCCGTGCGAGTGTCGCTGTCGGAGGCGGGGGCATTCA
CCGTGGCGAATCGCGGGCCTGTGCTGGCCGAGAACGACCTGGCACGCCTGATGAAGCCGTTCGAGCGTGGCGCGACAACA
GCCAGGGGCAGCGGCCTCGGGCTGGCCATCGTCGAGGCAATTGTTCGCGGGGCTGGCGCCACGCTTACCGCGCATAGTCC
GGCACCGGGGTGGCCGGATGGCTTGTGGATCACAATCGACGGCTTGCCGCTTGCCACGATGGGGCCTCGGTGA

Upstream 100 bases:

>100_bases
ACACCATCGAGGTCCATATGAGCCGGCTGCGCAAGAAACTTGGCGCGGATGTCATCGAGACCTTGCGCGGGCTAGGCTAT
CGACTCAGGCGGGACTGACG

Downstream 100 bases:

>100_bases
CCCCTCCGCCAACTCAGCGATATGTGGCGCCTGGCAGCAAATCCGCAGCCAGCGAATCTCATTCCGTTTAACCACTATCA
ACTGTTGGCCAGCTTCTGCA

Product: two-component signal transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 450; Mature: 450

Protein sequence:

>450_residues
MLRSLQGRLSAALVAGLVVLACAAAAASIHVLRQEVDRMSDSALQEAAQRLLPLALTEIMRREADDDEDDSSRVTAVRPH
DELLTYVVRDDKGSLLLQSHDADLSVFPAGLKPGFSSTLSHRIYTEPGLQGTVALTIAEPLAARRQAKVAAALSVVRVLI
LFLPVGLIGIWLIVRTGLQPIRRFCGSIAARGQSDLTSLEKSGLPTEIAPVADAVNGLMARLDRALAAERSFTANSAHEL
RTPIAAALAQTQRLKADMPTDDMRERVQNVEHSLRTLARLSESLMQLAKAENGRVLGDATQDLRPVIELVIEDFRRIAHT
PNPITLDLPDQPVESWIDPDAFAIVVRNLVDNAQKHGARGEPVRVSLSEAGAFTVANRGPVLAENDLARLMKPFERGATT
ARGSGLGLAIVEAIVRGAGATLTAHSPAPGWPDGLWITIDGLPLATMGPR

Sequences:

>Translated_450_residues
MLRSLQGRLSAALVAGLVVLACAAAAASIHVLRQEVDRMSDSALQEAAQRLLPLALTEIMRREADDDEDDSSRVTAVRPH
DELLTYVVRDDKGSLLLQSHDADLSVFPAGLKPGFSSTLSHRIYTEPGLQGTVALTIAEPLAARRQAKVAAALSVVRVLI
LFLPVGLIGIWLIVRTGLQPIRRFCGSIAARGQSDLTSLEKSGLPTEIAPVADAVNGLMARLDRALAAERSFTANSAHEL
RTPIAAALAQTQRLKADMPTDDMRERVQNVEHSLRTLARLSESLMQLAKAENGRVLGDATQDLRPVIELVIEDFRRIAHT
PNPITLDLPDQPVESWIDPDAFAIVVRNLVDNAQKHGARGEPVRVSLSEAGAFTVANRGPVLAENDLARLMKPFERGATT
ARGSGLGLAIVEAIVRGAGATLTAHSPAPGWPDGLWITIDGLPLATMGPR
>Mature_450_residues
MLRSLQGRLSAALVAGLVVLACAAAAASIHVLRQEVDRMSDSALQEAAQRLLPLALTEIMRREADDDEDDSSRVTAVRPH
DELLTYVVRDDKGSLLLQSHDADLSVFPAGLKPGFSSTLSHRIYTEPGLQGTVALTIAEPLAARRQAKVAAALSVVRVLI
LFLPVGLIGIWLIVRTGLQPIRRFCGSIAARGQSDLTSLEKSGLPTEIAPVADAVNGLMARLDRALAAERSFTANSAHEL
RTPIAAALAQTQRLKADMPTDDMRERVQNVEHSLRTLARLSESLMQLAKAENGRVLGDATQDLRPVIELVIEDFRRIAHT
PNPITLDLPDQPVESWIDPDAFAIVVRNLVDNAQKHGARGEPVRVSLSEAGAFTVANRGPVLAENDLARLMKPFERGATT
ARGSGLGLAIVEAIVRGAGATLTAHSPAPGWPDGLWITIDGLPLATMGPR

Specific function: Member of a two-component regulatory system qseB/qseC. May activate qseB by phosphorylation [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1789403, Length=440, Percent_Identity=26.3636363636364, Blast_Score=103, Evalue=3e-23,
Organism=Escherichia coli, GI1790551, Length=263, Percent_Identity=27.3764258555133, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI1788393, Length=263, Percent_Identity=27.3764258555133, Blast_Score=80, Evalue=4e-16,
Organism=Escherichia coli, GI1786783, Length=293, Percent_Identity=25.5972696245734, Blast_Score=79, Evalue=7e-16,
Organism=Escherichia coli, GI1788279, Length=302, Percent_Identity=24.5033112582781, Blast_Score=78, Evalue=1e-15,
Organism=Escherichia coli, GI87082128, Length=275, Percent_Identity=26.5454545454545, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1789149, Length=338, Percent_Identity=25.1479289940828, Blast_Score=62, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 48223; Mature: 48223

Theoretical pI: Translated: 6.44; Mature: 6.44

Prosite motif: PS00013 PROKAR_LIPOPROTEIN ; PS50885 HAMP ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLRSLQGRLSAALVAGLVVLACAAAAASIHVLRQEVDRMSDSALQEAAQRLLPLALTEIM
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RREADDDEDDSSRVTAVRPHDELLTYVVRDDKGSLLLQSHDADLSVFPAGLKPGFSSTLS
HHCCCCCCCCCCCEEEECCHHHHHHHHEECCCCCEEEEECCCCCEEECCCCCCCHHHHHC
HRIYTEPGLQGTVALTIAEPLAARRQAKVAAALSVVRVLILFLPVGLIGIWLIVRTGLQP
CCCCCCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHH
IRRFCGSIAARGQSDLTSLEKSGLPTEIAPVADAVNGLMARLDRALAAERSFTANSAHEL
HHHHHHHHHCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHH
RTPIAAALAQTQRLKADMPTDDMRERVQNVEHSLRTLARLSESLMQLAKAENGRVLGDAT
HHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEECCCH
QDLRPVIELVIEDFRRIAHTPNPITLDLPDQPVESWIDPDAFAIVVRNLVDNAQKHGARG
HHHHHHHHHHHHHHHHHHCCCCCEEECCCCCHHHHHCCCHHHHHHHHHHHHHHHHCCCCC
EPVRVSLSEAGAFTVANRGPVLAENDLARLMKPFERGATTARGSGLGLAIVEAIVRGAGA
CCEEEEECCCCEEEECCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHCCCC
TLTAHSPAPGWPDGLWITIDGLPLATMGPR
EEEECCCCCCCCCCEEEEECCEECCCCCCC
>Mature Secondary Structure
MLRSLQGRLSAALVAGLVVLACAAAAASIHVLRQEVDRMSDSALQEAAQRLLPLALTEIM
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RREADDDEDDSSRVTAVRPHDELLTYVVRDDKGSLLLQSHDADLSVFPAGLKPGFSSTLS
HHCCCCCCCCCCCEEEECCHHHHHHHHEECCCCCEEEEECCCCCEEECCCCCCCHHHHHC
HRIYTEPGLQGTVALTIAEPLAARRQAKVAAALSVVRVLILFLPVGLIGIWLIVRTGLQP
CCCCCCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHH
IRRFCGSIAARGQSDLTSLEKSGLPTEIAPVADAVNGLMARLDRALAAERSFTANSAHEL
HHHHHHHHHCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHH
RTPIAAALAQTQRLKADMPTDDMRERVQNVEHSLRTLARLSESLMQLAKAENGRVLGDAT
HHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEECCCH
QDLRPVIELVIEDFRRIAHTPNPITLDLPDQPVESWIDPDAFAIVVRNLVDNAQKHGARG
HHHHHHHHHHHHHHHHHHCCCCCEEECCCCCHHHHHCCCHHHHHHHHHHHHHHHHCCCCC
EPVRVSLSEAGAFTVANRGPVLAENDLARLMKPFERGATTARGSGLGLAIVEAIVRGAGA
CCEEEEECCCCEEEECCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHCCCC
TLTAHSPAPGWPDGLWITIDGLPLATMGPR
EEEECCCCCCCCCCEEEEECCEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800; 10675023 [H]