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The map label for this gene is hlyB [H]

Identifier: 94314259

GI number: 94314259

Start: 2050600

End: 2052366

Strand: Reverse

Name: hlyB [H]

Synonym: Rmet_5340

Alternate gene names: 94314259

Gene position: 2052366-2050600 (Counterclockwise)

Preceding gene: 291481563

Following gene: 94314258

Centisome position: 79.55

GC content: 63.95

Gene sequence:

>1767_bases
ATGAGAATCAAGTCGATGGCGATGACTCGCCCACTTCATGCGAGCCTGCTGCTGCTCGGCCTGTCCACGTGCGCGGAGGC
GCAGCCGACTGGCCCGGGCCGGAGCCCGGCCACCACCGCCGCCGATCAACAACAACTCACCCGCCAGCAACAGGAAGCCC
GCGAGCGCGCCCAGGCCATCGAGGCTCCCGGCGTGCGCGCGCAGGAGATCACGCCGCTCGTCTATCCGACGCTGCCGACC
GAGACGCCATGTTTCCGCATCGACCGCTTCGTGCTCGAAGTCCCGGCCGATCTGCCCGATAGCGTCCAGGTACACGGTGC
TTCTACGCTGCCGATGGACCCGTTTGCTTTTGCCCGAGCATGGCTCGATCACTATCAGGGTGCGTGTGTCGGCAGGCAGG
GCCTGGATATGCTGACCATGGGTGTGTCTCAGGCCATTCTGAGTCGGGGCTATGTCACCACGCGCGTGTTACTGCCGCAG
CAGGACCTCAGCACCGGGACCTTGCGATTGGCGCTGATCCCCGGCGTGATCGGCGAGTTGCGTTTTGCGGAACCGGATAC
GCGTGGCACATGGAAGTCCGCGTTTCCGGCACGTTCGGGCGATCTCCTGAATCTGCGCGACCTGGAGCAGGGGCTGGAGC
AAATGAAGCGTGTGGCCAGTCAGGATGCCGAGATGCAGATCGTGCCGACTGCCGTGCCGGGCGTGAGCGATGTGGTCATC
GCGGTCAAGCGGGCGAAGGCGTGGACCGTGGTGGCGTCGATTGACAACTCGGGCACGGAGGCAACGGGAAAATGGCTCGG
CAATCTGAGTCTGGGCATCGATAACCCACTGGGTCTCAACGATCTGTTCAACGTCGGCTATATGCAGGACGTTGAGCTTG
GCAATCGGAAGCACGGCACGCGCGGCTGGAACGGCTTCTACTCGGTGCCGTGGGGTTACTGGACGGGCACGCTGTCCGCG
TACTCGAACACGTACTACCAGCAGATTGCGGGCGTCAACCAGACCTTTGTCTCGAGCGGGAATTCGCAGACGGTGGACAT
GAAGCTGCAGCGCGTGATTCGCCGCAGCCAGAGCGACGTACTGGGTCTGCAGTTCCGGCTCTCGCGCCGCTTTGGCGAGA
GCTTCATCGAGGATACGGCAATCCCCCAGCAGCGGCGCAACAACACGTTTGTGGAGGCCGGCTTCACCGATCGCCATTAC
TTCGGCTCGGCGCAGTTCGATGGCAGCCTCGTGTATCGCCAGGGCATCGGCGGATTCGGCTCGCAGGCCGACACGCTGGC
TGTGAACGGCGGGCCGACATGGCGCTACAGCATGGTCGTGGCCGATGCCAATCTGTCGGCGCCCTTCCGGCTCGGCGACC
AGATGTTGCGTTACGTGACGACCTTCCGTGGCCAGTACACCGGCGATCGCCTGTATGCGCTGGACATGATGACCATCGGC
AGCCGCTATACGGTGCGCGGCTTCGACGGTGAGATGCTGTTGGCCGGCGATAGTGGCTTCTACTGGCGCAACGAACTGCA
GGCACCCGTCGCCAACACCGGGCAGGCGCTGTATGCGGGGCTGGACTACGGACGTGTGTTCGGGCCGTCGACGGTCGGGC
TGGTTGGTACGCAATTGATCGGCGCGGTGCTGGGCCTGCGCGGTGGCTTTGGTTCGAAGTTCGGGCGGCTGTCCTATGAC
TTCTTTGTCGGCCTGCCCGTGTACAAGCCCGCCGCCTTTCATACGTCTGGCGTCACCGGCGGGATGCAGGTGGCGTACCA
GTACTGA

Upstream 100 bases:

>100_bases
TGGTGTCGCAAGCAATCTCATGGCACTACTTGACGCATCGTGTATCGCCGCCATGCCTACGGGCGGCACGATGACTGGCG
TCGAATTGAAGCATTAACCC

Downstream 100 bases:

>100_bases
GTTTTCATACCGGCGGCTGTCGCCGCTTTCATCAACGTAGTCAAACAGGAGAAATTACGTGATTCGATTCAAGACCTATG
CTGCGGTGGGCTTCGTGGCG

Product: hemolysin activator translocator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 588; Mature: 588

Protein sequence:

>588_residues
MRIKSMAMTRPLHASLLLLGLSTCAEAQPTGPGRSPATTAADQQQLTRQQQEARERAQAIEAPGVRAQEITPLVYPTLPT
ETPCFRIDRFVLEVPADLPDSVQVHGASTLPMDPFAFARAWLDHYQGACVGRQGLDMLTMGVSQAILSRGYVTTRVLLPQ
QDLSTGTLRLALIPGVIGELRFAEPDTRGTWKSAFPARSGDLLNLRDLEQGLEQMKRVASQDAEMQIVPTAVPGVSDVVI
AVKRAKAWTVVASIDNSGTEATGKWLGNLSLGIDNPLGLNDLFNVGYMQDVELGNRKHGTRGWNGFYSVPWGYWTGTLSA
YSNTYYQQIAGVNQTFVSSGNSQTVDMKLQRVIRRSQSDVLGLQFRLSRRFGESFIEDTAIPQQRRNNTFVEAGFTDRHY
FGSAQFDGSLVYRQGIGGFGSQADTLAVNGGPTWRYSMVVADANLSAPFRLGDQMLRYVTTFRGQYTGDRLYALDMMTIG
SRYTVRGFDGEMLLAGDSGFYWRNELQAPVANTGQALYAGLDYGRVFGPSTVGLVGTQLIGAVLGLRGGFGSKFGRLSYD
FFVGLPVYKPAAFHTSGVTGGMQVAYQY

Sequences:

>Translated_588_residues
MRIKSMAMTRPLHASLLLLGLSTCAEAQPTGPGRSPATTAADQQQLTRQQQEARERAQAIEAPGVRAQEITPLVYPTLPT
ETPCFRIDRFVLEVPADLPDSVQVHGASTLPMDPFAFARAWLDHYQGACVGRQGLDMLTMGVSQAILSRGYVTTRVLLPQ
QDLSTGTLRLALIPGVIGELRFAEPDTRGTWKSAFPARSGDLLNLRDLEQGLEQMKRVASQDAEMQIVPTAVPGVSDVVI
AVKRAKAWTVVASIDNSGTEATGKWLGNLSLGIDNPLGLNDLFNVGYMQDVELGNRKHGTRGWNGFYSVPWGYWTGTLSA
YSNTYYQQIAGVNQTFVSSGNSQTVDMKLQRVIRRSQSDVLGLQFRLSRRFGESFIEDTAIPQQRRNNTFVEAGFTDRHY
FGSAQFDGSLVYRQGIGGFGSQADTLAVNGGPTWRYSMVVADANLSAPFRLGDQMLRYVTTFRGQYTGDRLYALDMMTIG
SRYTVRGFDGEMLLAGDSGFYWRNELQAPVANTGQALYAGLDYGRVFGPSTVGLVGTQLIGAVLGLRGGFGSKFGRLSYD
FFVGLPVYKPAAFHTSGVTGGMQVAYQY
>Mature_588_residues
MRIKSMAMTRPLHASLLLLGLSTCAEAQPTGPGRSPATTAADQQQLTRQQQEARERAQAIEAPGVRAQEITPLVYPTLPT
ETPCFRIDRFVLEVPADLPDSVQVHGASTLPMDPFAFARAWLDHYQGACVGRQGLDMLTMGVSQAILSRGYVTTRVLLPQ
QDLSTGTLRLALIPGVIGELRFAEPDTRGTWKSAFPARSGDLLNLRDLEQGLEQMKRVASQDAEMQIVPTAVPGVSDVVI
AVKRAKAWTVVASIDNSGTEATGKWLGNLSLGIDNPLGLNDLFNVGYMQDVELGNRKHGTRGWNGFYSVPWGYWTGTLSA
YSNTYYQQIAGVNQTFVSSGNSQTVDMKLQRVIRRSQSDVLGLQFRLSRRFGESFIEDTAIPQQRRNNTFVEAGFTDRHY
FGSAQFDGSLVYRQGIGGFGSQADTLAVNGGPTWRYSMVVADANLSAPFRLGDQMLRYVTTFRGQYTGDRLYALDMMTIG
SRYTVRGFDGEMLLAGDSGFYWRNELQAPVANTGQALYAGLDYGRVFGPSTVGLVGTQLIGAVLGLRGGFGSKFGRLSYD
FFVGLPVYKPAAFHTSGVTGGMQVAYQY

Specific function: Member of a two partner secretion pathway (TPS) in which it mediates the secretion of hemolysin [H]

COG id: COG2831

COG function: function code U; Hemolysin activation/secretion protein

Gene ontology:

Cell location: Cell outer membrane [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tpsB (TC 1.B.20) family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005565
- InterPro:   IPR013686 [H]

Pfam domain/function: PF08479 POTRA_2; PF03865 ShlB [H]

EC number: NA

Molecular weight: Translated: 64250; Mature: 64250

Theoretical pI: Translated: 8.62; Mature: 8.62

Prosite motif: PS00430 TONB_DEPENDENT_REC_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRIKSMAMTRPLHASLLLLGLSTCAEAQPTGPGRSPATTAADQQQLTRQQQEARERAQAI
CCCHHHHHCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
EAPGVRAQEITPLVYPTLPTETPCFRIDRFVLEVPADLPDSVQVHGASTLPMDPFAFARA
CCCCCCHHHCCCEEECCCCCCCCHHHHHHHHEECCCCCCCCEEECCCCCCCCCHHHHHHH
WLDHYQGACVGRQGLDMLTMGVSQAILSRGYVTTRVLLPQQDLSTGTLRLALIPGVIGEL
HHHHHCCCCCCCCCCHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCEEEEEECCCHHHCC
RFAEPDTRGTWKSAFPARSGDLLNLRDLEQGLEQMKRVASQDAEMQIVPTAVPGVSDVVI
EECCCCCCCCCCCCCCCCCCCEECHHHHHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHH
AVKRAKAWTVVASIDNSGTEATGKWLGNLSLGIDNPLGLNDLFNVGYMQDVELGNRKHGT
EEECCCEEEEEEEECCCCCCCCHHEEEEEEECCCCCCCCHHHHCCCCEEECCCCCCCCCC
RGWNGFYSVPWGYWTGTLSAYSNTYYQQIAGVNQTFVSSGNSQTVDMKLQRVIRRSQSDV
CCCCCEEECCCCHHHHHHHHHHHHHHHHHCCCCHHHHCCCCCEEHHHHHHHHHHHCCCCE
LGLQFRLSRRFGESFIEDTAIPQQRRNNTFVEAGFTDRHYFGSAQFDGSLVYRQGIGGFG
EEHHHHHHHHHHHHHHHHCCCCHHHCCCCEEEECCCCCEECCCCCCCCEEEEECCCCCCC
SQADTLAVNGGPTWRYSMVVADANLSAPFRLGDQMLRYVTTFRGQYTGDRLYALDMMTIG
CCCCEEEECCCCCEEEEEEEEECCCCCCHHHHHHHHHHHHHHCCCCCCCEEEEEEEEECC
SRYTVRGFDGEMLLAGDSGFYWRNELQAPVANTGQALYAGLDYGRVFGPSTVGLVGTQLI
CEEEEECCCCCEEEECCCCCEECCCCCCCCCCCCCEEEEECCCCCCCCCCHHHHHHHHHH
GAVLGLRGGFGSKFGRLSYDFFVGLPVYKPAAFHTSGVTGGMQVAYQY
HHHHHCCCCCCCCCCCEEEEEEECCCCCCCCCEECCCCCCCEEEEEEC
>Mature Secondary Structure
MRIKSMAMTRPLHASLLLLGLSTCAEAQPTGPGRSPATTAADQQQLTRQQQEARERAQAI
CCCHHHHHCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
EAPGVRAQEITPLVYPTLPTETPCFRIDRFVLEVPADLPDSVQVHGASTLPMDPFAFARA
CCCCCCHHHCCCEEECCCCCCCCHHHHHHHHEECCCCCCCCEEECCCCCCCCCHHHHHHH
WLDHYQGACVGRQGLDMLTMGVSQAILSRGYVTTRVLLPQQDLSTGTLRLALIPGVIGEL
HHHHHCCCCCCCCCCHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCEEEEEECCCHHHCC
RFAEPDTRGTWKSAFPARSGDLLNLRDLEQGLEQMKRVASQDAEMQIVPTAVPGVSDVVI
EECCCCCCCCCCCCCCCCCCCEECHHHHHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHH
AVKRAKAWTVVASIDNSGTEATGKWLGNLSLGIDNPLGLNDLFNVGYMQDVELGNRKHGT
EEECCCEEEEEEEECCCCCCCCHHEEEEEEECCCCCCCCHHHHCCCCEEECCCCCCCCCC
RGWNGFYSVPWGYWTGTLSAYSNTYYQQIAGVNQTFVSSGNSQTVDMKLQRVIRRSQSDV
CCCCCEEECCCCHHHHHHHHHHHHHHHHHCCCCHHHHCCCCCEEHHHHHHHHHHHCCCCE
LGLQFRLSRRFGESFIEDTAIPQQRRNNTFVEAGFTDRHYFGSAQFDGSLVYRQGIGGFG
EEHHHHHHHHHHHHHHHHCCCCHHHCCCCEEEECCCCCEECCCCCCCCEEEEECCCCCCC
SQADTLAVNGGPTWRYSMVVADANLSAPFRLGDQMLRYVTTFRGQYTGDRLYALDMMTIG
CCCCEEEECCCCCEEEEEEEEECCCCCCHHHHHHHHHHHHHHCCCCCCCEEEEEEEEECC
SRYTVRGFDGEMLLAGDSGFYWRNELQAPVANTGQALYAGLDYGRVFGPSTVGLVGTQLI
CEEEEECCCCCEEEECCCCCEECCCCCCCCCCCCCEEEEECCCCCCCCCCHHHHHHHHHH
GAVLGLRGGFGSKFGRLSYDFFVGLPVYKPAAFHTSGVTGGMQVAYQY
HHHHHCCCCCCCCCCCEEEEEEECCCCCCCCCEECCCCCCCEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 3290200 [H]