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The map label for this gene is tcrA [H]

Identifier: 94314250

GI number: 94314250

Start: 2043417

End: 2044094

Strand: Direct

Name: tcrA [H]

Synonym: Rmet_5331

Alternate gene names: 94314250

Gene position: 2043417-2044094 (Clockwise)

Preceding gene: 94314246

Following gene: 94314251

Centisome position: 79.2

GC content: 64.31

Gene sequence:

>678_bases
ATGAGGATCCTATTGGTAGATGACGACCAGAAGGCAGCGCGACTGCTGGCCCGTGGTCTGCAAGAAGAAGGTTATGACGT
GGAGACCGCCCATTCGGTTGACGTGGCGGCGGCTCACAATTGTTACGCGTTCAGTCTGCTGATTCTCGACTGGATGCTCC
CGGGCAAAAGTGGCGTCGAGTTCTGCCGGGAATTGCGCGAGCAGGGCGTGCGCACGCCGATCCTGATGCTGACGGCGCGC
GATGCAATCAATGACCGCATCACCGGGCTGGACACGGGCGCCGACGACTATCTGACCAAACCCTTCGTCTTTGAGGAACT
GCTCGCGCACGTGCGGGCCCTGCTGCGGCGTGTGGAGCTGGCCCAACCCGCCCCGATCACGCTGAACGACCTTGTCATCG
ACCCGCAGACCCGTGGCGTCACGCGGGCCGGCGCGCGGCTCGATCTCACGCCGAAGGAGTACGCGATCCTCATCCTGCTG
GTGACGCACGCCGGGGAGATCGTCAGCCGGGCACAGCTTGCGGAACACATCTGGCACGCGGACCTGATCGCCATCGACAA
CCTGATCGACGTGCACATGAAGAACCTGCGCCGCAAGCTCGACCCACCGGGCATGGCGGCGCTGATCCAAACCGTGCGGG
GCCAGGGCTTCCGCATCTCGCCATCGGGGGCCCTCTGA

Upstream 100 bases:

>100_bases
AGCCCCCGTGCACTCTGAATTCTTCTTCAGGCAGGGCCGTATGCGTAACATGCGGAAAAGTCGGCTGATAGAATCAGACC
CGACCCGGAAAGGCGAACCC

Downstream 100 bases:

>100_bases
CGTGCTGAACTTCCGGCAGCGGCTGGTCCTGACCCACTGGACCGTCATCGTGGTGATCGTGGCCTGCTCGGCGTTGGCCG
GGTGGTGGCAGCTATCGCGC

Product: transcriptional regulator two components regulatory system

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 225; Mature: 225

Protein sequence:

>225_residues
MRILLVDDDQKAARLLARGLQEEGYDVETAHSVDVAAAHNCYAFSLLILDWMLPGKSGVEFCRELREQGVRTPILMLTAR
DAINDRITGLDTGADDYLTKPFVFEELLAHVRALLRRVELAQPAPITLNDLVIDPQTRGVTRAGARLDLTPKEYAILILL
VTHAGEIVSRAQLAEHIWHADLIAIDNLIDVHMKNLRRKLDPPGMAALIQTVRGQGFRISPSGAL

Sequences:

>Translated_225_residues
MRILLVDDDQKAARLLARGLQEEGYDVETAHSVDVAAAHNCYAFSLLILDWMLPGKSGVEFCRELREQGVRTPILMLTAR
DAINDRITGLDTGADDYLTKPFVFEELLAHVRALLRRVELAQPAPITLNDLVIDPQTRGVTRAGARLDLTPKEYAILILL
VTHAGEIVSRAQLAEHIWHADLIAIDNLIDVHMKNLRRKLDPPGMAALIQTVRGQGFRISPSGAL
>Mature_225_residues
MRILLVDDDQKAARLLARGLQEEGYDVETAHSVDVAAAHNCYAFSLLILDWMLPGKSGVEFCRELREQGVRTPILMLTAR
DAINDRITGLDTGADDYLTKPFVFEELLAHVRALLRRVELAQPAPITLNDLVIDPQTRGVTRAGARLDLTPKEYAILILL
VTHAGEIVSRAQLAEHIWHADLIAIDNLIDVHMKNLRRKLDPPGMAALIQTVRGQGFRISPSGAL

Specific function: Member of the three-protein two-component system HK1/HK2/tcrA [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1786599, Length=223, Percent_Identity=37.6681614349776, Blast_Score=163, Evalue=8e-42,
Organism=Escherichia coli, GI1786784, Length=227, Percent_Identity=40.9691629955947, Blast_Score=160, Evalue=7e-41,
Organism=Escherichia coli, GI87082012, Length=220, Percent_Identity=40.4545454545455, Blast_Score=154, Evalue=4e-39,
Organism=Escherichia coli, GI1789402, Length=221, Percent_Identity=38.4615384615385, Blast_Score=143, Evalue=9e-36,
Organism=Escherichia coli, GI1790552, Length=222, Percent_Identity=40.0900900900901, Blast_Score=142, Evalue=2e-35,
Organism=Escherichia coli, GI2367329, Length=225, Percent_Identity=39.1111111111111, Blast_Score=139, Evalue=2e-34,
Organism=Escherichia coli, GI1789809, Length=232, Percent_Identity=38.3620689655172, Blast_Score=138, Evalue=3e-34,
Organism=Escherichia coli, GI1788394, Length=223, Percent_Identity=37.219730941704, Blast_Score=122, Evalue=2e-29,
Organism=Escherichia coli, GI1786911, Length=224, Percent_Identity=34.375, Blast_Score=117, Evalue=9e-28,
Organism=Escherichia coli, GI1790860, Length=222, Percent_Identity=36.036036036036, Blast_Score=115, Evalue=3e-27,
Organism=Escherichia coli, GI1787375, Length=218, Percent_Identity=33.4862385321101, Blast_Score=114, Evalue=8e-27,
Organism=Escherichia coli, GI1790863, Length=230, Percent_Identity=33.0434782608696, Blast_Score=106, Evalue=1e-24,
Organism=Escherichia coli, GI1787229, Length=228, Percent_Identity=33.7719298245614, Blast_Score=98, Evalue=5e-22,
Organism=Escherichia coli, GI145693140, Length=233, Percent_Identity=30.9012875536481, Blast_Score=88, Evalue=4e-19,
Organism=Escherichia coli, GI1788550, Length=111, Percent_Identity=28.8288288288288, Blast_Score=60, Evalue=9e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 24940; Mature: 24940

Theoretical pI: Translated: 6.16; Mature: 6.16

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS00217 SUGAR_TRANSPORT_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRILLVDDDQKAARLLARGLQEEGYDVETAHSVDVAAAHNCYAFSLLILDWMLPGKSGVE
CEEEEECCCHHHHHHHHHHHHHCCCCCCCCCCCCHHHHCCHHHHHHHHHHHHCCCCHHHH
FCRELREQGVRTPILMLTARDAINDRITGLDTGADDYLTKPFVFEELLAHVRALLRRVEL
HHHHHHHCCCCCCEEEEEECHHHHCCCCCCCCCCHHHCCCHHHHHHHHHHHHHHHHHHHH
AQPAPITLNDLVIDPQTRGVTRAGARLDLTPKEYAILILLVTHAGEIVSRAQLAEHIWHA
CCCCCCCHHHEEECCCCCCCCCCCCEECCCCHHHEEEEEEEHHHHHHHHHHHHHHHHHHH
DLIAIDNLIDVHMKNLRRKLDPPGMAALIQTVRGQGFRISPSGAL
HHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCEEECCCCCC
>Mature Secondary Structure
MRILLVDDDQKAARLLARGLQEEGYDVETAHSVDVAAAHNCYAFSLLILDWMLPGKSGVE
CEEEEECCCHHHHHHHHHHHHHCCCCCCCCCCCCHHHHCCHHHHHHHHHHHHCCCCHHHH
FCRELREQGVRTPILMLTARDAINDRITGLDTGADDYLTKPFVFEELLAHVRALLRRVEL
HHHHHHHCCCCCCEEEEEECHHHHCCCCCCCCCCHHHCCCHHHHHHHHHHHHHHHHHHHH
AQPAPITLNDLVIDPQTRGVTRAGARLDLTPKEYAILILLVTHAGEIVSRAQLAEHIWHA
CCCCCCCHHHEEECCCCCCCCCCCCEECCCCHHHEEEEEEEHHHHHHHHHHHHHHHHHHH
DLIAIDNLIDVHMKNLRRKLDPPGMAALIQTVRGQGFRISPSGAL
HHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9634230 [H]