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The map label for this gene is zneR [H]

Identifier: 94314245

GI number: 94314245

Start: 2035367

End: 2036032

Strand: Direct

Name: zneR [H]

Synonym: Rmet_5326

Alternate gene names: 94314245

Gene position: 2035367-2036032 (Clockwise)

Preceding gene: 94314244

Following gene: 94314246

Centisome position: 78.89

GC content: 65.92

Gene sequence:

>666_bases
ATGCGGGTGCTGCTGGTCGAGGATGACCGCATGATCGGACAGGTGGTGCAGGACGCCCTGAAGGACGCCTCCTGCGCCGC
CGACTGGGTCGAGGATGGACAGGCCGCACTGGACGCGCTGGATCGCCAACACTATGACGTGGTCTTGCTGGATCTGGGCC
TGCCACGCAAGAGCGGCCATGCGGTGCTGACTTCGCTGCGCGCGCGTGGCAGCGCCGTGCCGGTGCTGATCCTCACGGCG
CGGGACGCACTCGAAGACCGCATCGGCGGGCTCGATGCGGGTGCCGACGACTATCTGGTCAAGCCATTCGAGATGGATGA
ACTGCTCGCGCGAATGCGGGCTGTGTGGCGCCGGAGAAGTGGTCTGGCGTCATCGGTGCTCGGCAATGGCCGCGTCTCGC
TGGATCTGTCGACCCGGCAGGCCACCCTGACGGGCGGCGCGCCCCAGCAACTCACGAATCGCGAGTTCGCGCTGCTGCAG
GCGTTGCTGGCACGCCCAGGCGCAATCCTGTCGCGTGCCGAGCTTGAAGAGCGCATCTATGGCTGGGGCGATGAAGTGGA
AAGCAATGCGGTCGAGTTCCTGATCCACGGCCTGCGCAGGAAGCTTGGCAGCACCATCATCAGAAACGTCAGGGGGGTGG
GATGGCAGGTGCCGAAGGAAGGCTGA

Upstream 100 bases:

>100_bases
GATCTGCATCCTGCTGCTGCCCCAGCGGGCGGCGGCCCGCGCAAGCCATTGAGCGGCGCTATGATGCGTGATGTCGGACA
CCGTTGGCATGGAGAACGCG

Downstream 100 bases:

>100_bases
AACACGCCGGGCCAAAGCACTCGGTCCAGCAACGGCTATCCCTCTGGGTATCGCTGGCGATCCTCGCGGTGGCGCTCATC
GGCGGCATCTTTTCGTTTGC

Product: two component transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 221; Mature: 221

Protein sequence:

>221_residues
MRVLLVEDDRMIGQVVQDALKDASCAADWVEDGQAALDALDRQHYDVVLLDLGLPRKSGHAVLTSLRARGSAVPVLILTA
RDALEDRIGGLDAGADDYLVKPFEMDELLARMRAVWRRRSGLASSVLGNGRVSLDLSTRQATLTGGAPQQLTNREFALLQ
ALLARPGAILSRAELEERIYGWGDEVESNAVEFLIHGLRRKLGSTIIRNVRGVGWQVPKEG

Sequences:

>Translated_221_residues
MRVLLVEDDRMIGQVVQDALKDASCAADWVEDGQAALDALDRQHYDVVLLDLGLPRKSGHAVLTSLRARGSAVPVLILTA
RDALEDRIGGLDAGADDYLVKPFEMDELLARMRAVWRRRSGLASSVLGNGRVSLDLSTRQATLTGGAPQQLTNREFALLQ
ALLARPGAILSRAELEERIYGWGDEVESNAVEFLIHGLRRKLGSTIIRNVRGVGWQVPKEG
>Mature_221_residues
MRVLLVEDDRMIGQVVQDALKDASCAADWVEDGQAALDALDRQHYDVVLLDLGLPRKSGHAVLTSLRARGSAVPVLILTA
RDALEDRIGGLDAGADDYLVKPFEMDELLARMRAVWRRRSGLASSVLGNGRVSLDLSTRQATLTGGAPQQLTNREFALLQ
ALLARPGAILSRAELEERIYGWGDEVESNAVEFLIHGLRRKLGSTIIRNVRGVGWQVPKEG

Specific function: Member of a two-component regulatory system qseB/qseC. Activates the flagella regulon by activating transcription of flhDC. Currently it is not known whether this effect is direct or not [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1789402, Length=217, Percent_Identity=48.3870967741936, Blast_Score=192, Evalue=2e-50,
Organism=Escherichia coli, GI1790552, Length=217, Percent_Identity=43.3179723502304, Blast_Score=169, Evalue=1e-43,
Organism=Escherichia coli, GI1787375, Length=219, Percent_Identity=34.2465753424658, Blast_Score=134, Evalue=4e-33,
Organism=Escherichia coli, GI87082012, Length=223, Percent_Identity=36.322869955157, Blast_Score=125, Evalue=2e-30,
Organism=Escherichia coli, GI1786784, Length=225, Percent_Identity=33.3333333333333, Blast_Score=125, Evalue=3e-30,
Organism=Escherichia coli, GI1786599, Length=222, Percent_Identity=34.6846846846847, Blast_Score=116, Evalue=1e-27,
Organism=Escherichia coli, GI1790860, Length=222, Percent_Identity=35.5855855855856, Blast_Score=110, Evalue=1e-25,
Organism=Escherichia coli, GI1788394, Length=229, Percent_Identity=33.1877729257642, Blast_Score=107, Evalue=6e-25,
Organism=Escherichia coli, GI1789809, Length=226, Percent_Identity=31.4159292035398, Blast_Score=105, Evalue=3e-24,
Organism=Escherichia coli, GI1786911, Length=202, Percent_Identity=36.1386138613861, Blast_Score=99, Evalue=2e-22,
Organism=Escherichia coli, GI2367329, Length=226, Percent_Identity=35.3982300884956, Blast_Score=90, Evalue=9e-20,
Organism=Escherichia coli, GI1787229, Length=221, Percent_Identity=29.4117647058824, Blast_Score=85, Evalue=4e-18,
Organism=Escherichia coli, GI1790863, Length=230, Percent_Identity=28.695652173913, Blast_Score=84, Evalue=5e-18,
Organism=Escherichia coli, GI1790299, Length=108, Percent_Identity=37.037037037037, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI1788550, Length=107, Percent_Identity=31.7757009345794, Blast_Score=69, Evalue=2e-13,
Organism=Escherichia coli, GI1790437, Length=110, Percent_Identity=33.6363636363636, Blast_Score=66, Evalue=2e-12,
Organism=Escherichia coli, GI1788191, Length=121, Percent_Identity=32.2314049586777, Blast_Score=62, Evalue=3e-11,
Organism=Escherichia coli, GI48994928, Length=129, Percent_Identity=34.1085271317829, Blast_Score=62, Evalue=4e-11,
Organism=Escherichia coli, GI145693140, Length=230, Percent_Identity=26.9565217391304, Blast_Score=61, Evalue=5e-11,
Organism=Saccharomyces cerevisiae, GI6322000, Length=179, Percent_Identity=27.3743016759777, Blast_Score=73, Evalue=4e-14,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 24160; Mature: 24160

Theoretical pI: Translated: 5.79; Mature: 5.79

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRVLLVEDDRMIGQVVQDALKDASCAADWVEDGQAALDALDRQHYDVVLLDLGLPRKSGH
CEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCH
AVLTSLRARGSAVPVLILTARDALEDRIGGLDAGADDYLVKPFEMDELLARMRAVWRRRS
HHHHHHHHCCCCCCEEEEECHHHHHHHHCCCCCCCCCCEECCCCHHHHHHHHHHHHHHHH
GLASSVLGNGRVSLDLSTRQATLTGGAPQQLTNREFALLQALLARPGAILSRAELEERIY
CHHHHHHCCCEEEEEECCCEEEECCCCHHHHCCHHHHHHHHHHHCCCHHHHHHHHHHHHC
GWGDEVESNAVEFLIHGLRRKLGSTIIRNVRGVGWQVPKEG
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure
MRVLLVEDDRMIGQVVQDALKDASCAADWVEDGQAALDALDRQHYDVVLLDLGLPRKSGH
CEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCH
AVLTSLRARGSAVPVLILTARDALEDRIGGLDAGADDYLVKPFEMDELLARMRAVWRRRS
HHHHHHHHCCCCCCEEEEECHHHHHHHHCCCCCCCCCCEECCCCHHHHHHHHHHHHHHHH
GLASSVLGNGRVSLDLSTRQATLTGGAPQQLTNREFALLQALLARPGAILSRAELEERIY
CHHHHHHCCCEEEEEECCCEEEECCCCHHHHCCHHHHHHHHHHHCCCHHHHHHHHHHHHC
GWGDEVESNAVEFLIHGLRRKLGSTIIRNVRGVGWQVPKEG
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796; 11929534 [H]