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The map label for this gene is virS [H]

Identifier: 94314214

GI number: 94314214

Start: 1996217

End: 1997260

Strand: Direct

Name: virS [H]

Synonym: Rmet_5295

Alternate gene names: 94314214

Gene position: 1996217-1997260 (Clockwise)

Preceding gene: 291481562

Following gene: 94314216

Centisome position: 77.37

GC content: 64.46

Gene sequence:

>1044_bases
ATGTCGTTACTTGTCCGGGCCGCAGCCCTCACCAACTACAGCGAGGTCGCTCGTGCCGCCGGGCTCGATCCGGTGCGGAT
GATGATGGACGCAGGAATCAGTCCGAGCGTGCTGCGCGAACCAGATCTCATGATTCCCGTCGAGCGTTACGGTCGCCTGC
TTCAGACCTCCGCAACCATGTCGGGCAACGAGAGCTTCGGGTTGGCCATGGCCGAGTCGCGCCTGCTGTCCAATCTCGGG
GCGGTCGGCATGCTGATCCGCGACCAGGCGACGCTGCGTGACTCCCTTACCCTGCTGATGCGCTATCAACCGTTGCTCAA
CGGCGCGCAGTCACTGGCGGTCGAGGATTGCGGCGGACGGGTCATCATTCGCGAGGTGCTGATCGCTGGCAACGCCCATC
AACCAACTCGCCAACGGGTTGAATTGGCGCTTGGGGTCATGGTGCGGTTGATACGTCAGCTCATCAAGGCCGACTGGCAG
CCGCAACGCGTGTGCCTGGAACATCCCGCGCCGCACGACCTGAGCGCGCACCACCGGTTCTTCGGTCCCCACGTCGAATT
TGATTGTGACTTCAACGGCATCATCTGCGCGAAGGCCGATCTCGATGCGCGCAACCCGTGGGCCGATCCGGCCATGGCGC
GCTACGCGCAGCAACTGATAGACGAGTCGGCCGTCATGCAACAGGCGACGATGCTCGAGGACGTGCGGCGCACCATCCTC
CTGCTGTTGCCCAGTGGCCGTTGCAGCGCCGAGCAGGTCGCCGATCACCTGGGCGTCGTGTGCCGCACGGTCCAGCGCCG
GCTGGCCGAACGTGGGCAGAGCTTCTCGTCGATGGTCAATGAAATCCGTACGGAGCTCGCGACGCGTCATGTCATCGAGA
GCGATCGTCCATTGACCGAGGTGGCGACCCTCCTCGGCTTTTCCGCGCCGAGCGGATTCTCGCGCTGGTATCACGCGCAG
TTCGGTTGCAGCCCCAAGGAGAGCCGGGCCGCGCATGGCACCACACGCCGACAGACCGCATCCGCACCAGCGAGCAATGC
GTGA

Upstream 100 bases:

>100_bases
GCAAACAACCTTACCTTCGCGCCTGAAGCTCGGGATTCCTCCCGCTTGACAACCCATTGCCGCTCTCTATCATGGGCTTT
CATTCTTTAGTCAGTTCCCG

Downstream 100 bases:

>100_bases
TGCTGGCCGCAGCTGATCACGCGTAAGCGGCGACCGGAGAATCAGCCACTAGCCAGCACGATCCGGCCGATCTCCTTCAC
GCTGGTCCATCCCCCCAATG

Product: AraC family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 347; Mature: 346

Protein sequence:

>347_residues
MSLLVRAAALTNYSEVARAAGLDPVRMMMDAGISPSVLREPDLMIPVERYGRLLQTSATMSGNESFGLAMAESRLLSNLG
AVGMLIRDQATLRDSLTLLMRYQPLLNGAQSLAVEDCGGRVIIREVLIAGNAHQPTRQRVELALGVMVRLIRQLIKADWQ
PQRVCLEHPAPHDLSAHHRFFGPHVEFDCDFNGIICAKADLDARNPWADPAMARYAQQLIDESAVMQQATMLEDVRRTIL
LLLPSGRCSAEQVADHLGVVCRTVQRRLAERGQSFSSMVNEIRTELATRHVIESDRPLTEVATLLGFSAPSGFSRWYHAQ
FGCSPKESRAAHGTTRRQTASAPASNA

Sequences:

>Translated_347_residues
MSLLVRAAALTNYSEVARAAGLDPVRMMMDAGISPSVLREPDLMIPVERYGRLLQTSATMSGNESFGLAMAESRLLSNLG
AVGMLIRDQATLRDSLTLLMRYQPLLNGAQSLAVEDCGGRVIIREVLIAGNAHQPTRQRVELALGVMVRLIRQLIKADWQ
PQRVCLEHPAPHDLSAHHRFFGPHVEFDCDFNGIICAKADLDARNPWADPAMARYAQQLIDESAVMQQATMLEDVRRTIL
LLLPSGRCSAEQVADHLGVVCRTVQRRLAERGQSFSSMVNEIRTELATRHVIESDRPLTEVATLLGFSAPSGFSRWYHAQ
FGCSPKESRAAHGTTRRQTASAPASNA
>Mature_346_residues
SLLVRAAALTNYSEVARAAGLDPVRMMMDAGISPSVLREPDLMIPVERYGRLLQTSATMSGNESFGLAMAESRLLSNLGA
VGMLIRDQATLRDSLTLLMRYQPLLNGAQSLAVEDCGGRVIIREVLIAGNAHQPTRQRVELALGVMVRLIRQLIKADWQP
QRVCLEHPAPHDLSAHHRFFGPHVEFDCDFNGIICAKADLDARNPWADPAMARYAQQLIDESAVMQQATMLEDVRRTILL
LLPSGRCSAEQVADHLGVVCRTVQRRLAERGQSFSSMVNEIRTELATRHVIESDRPLTEVATLLGFSAPSGFSRWYHAQF
GCSPKESRAAHGTTRRQTASAPASNA

Specific function: May have a role in the regulation of proteins necessary for virulence [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH araC/xylS-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1786758, Length=94, Percent_Identity=32.9787234042553, Blast_Score=64, Evalue=1e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009057
- InterPro:   IPR012287
- InterPro:   IPR018060 [H]

Pfam domain/function: PF00165 HTH_AraC [H]

EC number: NA

Molecular weight: Translated: 38192; Mature: 38061

Theoretical pI: Translated: 7.84; Mature: 7.84

Prosite motif: PS01124 HTH_ARAC_FAMILY_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
6.1 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
5.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLLVRAAALTNYSEVARAAGLDPVRMMMDAGISPSVLREPDLMIPVERYGRLLQTSATM
CCHHHHHHHHCCHHHHHHHCCCCHHHHHHHCCCCCHHHCCCCCEECHHHHHHHHHHHCCC
SGNESFGLAMAESRLLSNLGAVGMLIRDQATLRDSLTLLMRYQPLLNGAQSLAVEDCGGR
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCH
VIIREVLIAGNAHQPTRQRVELALGVMVRLIRQLIKADWQPQRVCLEHPAPHDLSAHHRF
HHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHCCCCCCCCCCCHHH
FGPHVEFDCDFNGIICAKADLDARNPWADPAMARYAQQLIDESAVMQQATMLEDVRRTIL
CCCCEEEECCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHE
LLLPSGRCSAEQVADHLGVVCRTVQRRLAERGQSFSSMVNEIRTELATRHVIESDRPLTE
EEECCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCHHH
VATLLGFSAPSGFSRWYHAQFGCSPKESRAAHGTTRRQTASAPASNA
HHHHHHCCCCCCHHHHHHHHCCCCCCHHHHHCCCCHHHHCCCCCCCC
>Mature Secondary Structure 
SLLVRAAALTNYSEVARAAGLDPVRMMMDAGISPSVLREPDLMIPVERYGRLLQTSATM
CHHHHHHHHCCHHHHHHHCCCCHHHHHHHCCCCCHHHCCCCCEECHHHHHHHHHHHCCC
SGNESFGLAMAESRLLSNLGAVGMLIRDQATLRDSLTLLMRYQPLLNGAQSLAVEDCGGR
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCH
VIIREVLIAGNAHQPTRQRVELALGVMVRLIRQLIKADWQPQRVCLEHPAPHDLSAHHRF
HHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHCCCCCCCCCCCHHH
FGPHVEFDCDFNGIICAKADLDARNPWADPAMARYAQQLIDESAVMQQATMLEDVRRTIL
CCCCEEEECCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHE
LLLPSGRCSAEQVADHLGVVCRTVQRRLAERGQSFSSMVNEIRTELATRHVIESDRPLTE
EEECCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCHHH
VATLLGFSAPSGFSRWYHAQFGCSPKESRAAHGTTRRQTASAPASNA
HHHHHHCCCCCCHHHHHHHHCCCCCCHHHHHCCCCHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8472958; 9634230; 12218036 [H]