Click here to switch to the map view.

The map label for this gene is tsr [H]

Identifier: 94314169

GI number: 94314169

Start: 1948822

End: 1950855

Strand: Reverse

Name: tsr [H]

Synonym: Rmet_5250

Alternate gene names: 94314169

Gene position: 1950855-1948822 (Counterclockwise)

Preceding gene: 94314178

Following gene: 94314166

Centisome position: 75.61

GC content: 67.31

Gene sequence:

>2034_bases
ATGGGCTTGCGAAAAATGGGGATCGGGGCGCGGCTGACCTTTGCTTTCAGTCTCGTGGTGCTGCTGCTCGCCGCGGTTGC
CGCGGTTGGGGTGTCGGCGCTGGGCAGCATGAACGATGCCATGCACATGGCGGTGGAGAAGCGGCTGCTGCGGGTGATCG
ATCTGAATCACGCCAAGGCGCAGGTGCTGACGATCGGTCTGATGGTGCGCGATGCGGCATTGACCGAGGATGCCGCGCTG
GTCACGGCGAACGCGGCGAAGATCGCCCGGTTCCGCGAGGAAATCGACGCGACGCTCGAACCGATCGGCAAGACCCTGGT
GGCGTCGGGCAACGCGGAATGGAAAGCCGTGTTCGAGCAACTGACGCAGGCACGCGCCACCTATGACGGTCAGCTCGACC
TGGTCATGCGCCAGCTGGGCGCAGGGGAATACGATGGCGCCCGCGCCGGGCTGACTGCCACGCTGCCGTCATCGCAGGCC
GCGTACTTCGACAAGCTGGACGCGATCGCCCAGCTTGGCCAGAAGCTGGCCGTGGAGGCGGTGGAGGATGCAACAGCGCG
CTACGCTTTTACGCGCAACCTTCTGATCGGCATGGCAGCTCTGGCGGCGATCATTGCCGCGCTGCTGGGTATCGGCATGA
CACGCTCGGTGACGCGTCCGGCCCGGCAGGCGCTTGATGCTGCCGAGGCGCTGGAGCAGGGCCAGCTTGCGCACACCATC
GAAGTACGCAGCCAGGATGAGATGGGCCGGATGCTCGGCGCGCTCGAGCGCGCCTTTGGCCAGCTCGGCACGCTGGTTCG
CGGCATCCAGCACGCGGCCGGTTCGATCGACACCGCCGCGCGCGAGATCTCCAGTGGCAATACCGATCTGTCCCGCCGTA
CCGAGCAGCAAGCGGCATCGCTGGAGCAGACTGCCGCGTCAATGGAGCAGTTGACGTCCACCGTGCGCCAGAACGCCGAG
AACGCGCGACAAGCCAACCAGCTTGCCGCGAACGCATCGGATGTCGCCACCGAAGGCGGCCGCGTGGTGCGCAGCGTGGT
GGATACGATGGACGGCATCACCCAGTCCTCGGCACGCGTGGCCGAGATCATCGGCGTCATCGAAGGTATCGCATTCCAGA
CCAACATTCTTGCGCTGAACGCCGCTGTGGAAGCGGCGCGTGCCGGCGAGCAAGGTCGTGGCTTCAGCGTTGTGGCGGCC
GAAGTGCGCAGCCTGGCGCAGCGTTCATCGTCGGCGGCCAAGGAAATCGGCGATCTGATCAATGGCTCCGTGCGGCAGGT
AAAGGAGGGCGCGCGCCAGGTCGAAGTAGCCGGCAAGACCATGGATGACATCGTCGGCGCGGTACGCCGCGTCACGGACA
TCATGGGCGAGATCACCGCCGCCAGCGAGGAGCAGAGCGCCGGCATCGAGCAGGTGGGCCTGGCGATTGCGCAGATGGAA
ACCGTGACGCAGCAGAATGCCGCGCTGGTGGAAGAAGCCAGTGCTGCCGCCGAAAGCCTGATGCAGCAGGCCGGCGGGCT
GGTGACGGAAGTCGCGCGTTTCGATCTGGGCCAGCAACAGCAGCGCGAAGTGCCGCGCGCGCCGGGGCCCGTGGCAGTCG
TTGCGCAGCCGGTTCAACCGGCGCCACGCTTGCCCGCTGCTGCGCCGAAGGCATTGACGCCGAGGCCATCGCCCCAGAAG
GCATTGACCCAGAAGGTATCGACCCAGAAGGTATCGACCCAGAAGGTATCGACCCAGAAGGTATCGACCCAGACGGCCGC
CGCTGCCCCGCAGCGCCCGGTGCAGCCATCACACCAATTGCGCGCGCCCGCAGTGCCCGCCGCCGTGCGACCGCCCGTGG
TACGCAAGACCTCGGCGGCCCCGGTACTGGCGCGCCAGCCAGCCACGCCAGCCAAGGCCCGCCAGCCGGTCACCCATCAG
CGCAAGGAACCCGTACTGGCTACGCCCTCGAGCCGTCGGCCCGTGGCAAAGGCGAGGCCATCGGCCGCACCGGTGCCCGC
GACGGCCGATGGCGGCGATTGGGAAACGTTCTGA

Upstream 100 bases:

>100_bases
GTCCGCCCGCGACGCCGCCGATAGGAGGCCGTGCGATGCCCGGTTTCGGGCGGATATCGCTCGTACGAACAATCGGATCA
CAAGAGAAAGGTACGAAGTG

Downstream 100 bases:

>100_bases
GCGCGCGCCGGTGCGAGGAGGCCAGCATTAGTGCGGATTAGCCCGGATTAGCCCGGATTAGCCCGGATTAGCCCGGATGT
CGCCGGGCACCGAAGCCCAG

Product: methyl-accepting chemotaxis protein, sensory transducer

Products: NA

Alternate protein names: MCP-I; Serine chemoreceptor protein [H]

Number of amino acids: Translated: 677; Mature: 676

Protein sequence:

>677_residues
MGLRKMGIGARLTFAFSLVVLLLAAVAAVGVSALGSMNDAMHMAVEKRLLRVIDLNHAKAQVLTIGLMVRDAALTEDAAL
VTANAAKIARFREEIDATLEPIGKTLVASGNAEWKAVFEQLTQARATYDGQLDLVMRQLGAGEYDGARAGLTATLPSSQA
AYFDKLDAIAQLGQKLAVEAVEDATARYAFTRNLLIGMAALAAIIAALLGIGMTRSVTRPARQALDAAEALEQGQLAHTI
EVRSQDEMGRMLGALERAFGQLGTLVRGIQHAAGSIDTAAREISSGNTDLSRRTEQQAASLEQTAASMEQLTSTVRQNAE
NARQANQLAANASDVATEGGRVVRSVVDTMDGITQSSARVAEIIGVIEGIAFQTNILALNAAVEAARAGEQGRGFSVVAA
EVRSLAQRSSSAAKEIGDLINGSVRQVKEGARQVEVAGKTMDDIVGAVRRVTDIMGEITAASEEQSAGIEQVGLAIAQME
TVTQQNAALVEEASAAAESLMQQAGGLVTEVARFDLGQQQQREVPRAPGPVAVVAQPVQPAPRLPAAAPKALTPRPSPQK
ALTQKVSTQKVSTQKVSTQKVSTQTAAAAPQRPVQPSHQLRAPAVPAAVRPPVVRKTSAAPVLARQPATPAKARQPVTHQ
RKEPVLATPSSRRPVAKARPSAAPVPATADGGDWETF

Sequences:

>Translated_677_residues
MGLRKMGIGARLTFAFSLVVLLLAAVAAVGVSALGSMNDAMHMAVEKRLLRVIDLNHAKAQVLTIGLMVRDAALTEDAAL
VTANAAKIARFREEIDATLEPIGKTLVASGNAEWKAVFEQLTQARATYDGQLDLVMRQLGAGEYDGARAGLTATLPSSQA
AYFDKLDAIAQLGQKLAVEAVEDATARYAFTRNLLIGMAALAAIIAALLGIGMTRSVTRPARQALDAAEALEQGQLAHTI
EVRSQDEMGRMLGALERAFGQLGTLVRGIQHAAGSIDTAAREISSGNTDLSRRTEQQAASLEQTAASMEQLTSTVRQNAE
NARQANQLAANASDVATEGGRVVRSVVDTMDGITQSSARVAEIIGVIEGIAFQTNILALNAAVEAARAGEQGRGFSVVAA
EVRSLAQRSSSAAKEIGDLINGSVRQVKEGARQVEVAGKTMDDIVGAVRRVTDIMGEITAASEEQSAGIEQVGLAIAQME
TVTQQNAALVEEASAAAESLMQQAGGLVTEVARFDLGQQQQREVPRAPGPVAVVAQPVQPAPRLPAAAPKALTPRPSPQK
ALTQKVSTQKVSTQKVSTQKVSTQTAAAAPQRPVQPSHQLRAPAVPAAVRPPVVRKTSAAPVLARQPATPAKARQPVTHQ
RKEPVLATPSSRRPVAKARPSAAPVPATADGGDWETF
>Mature_676_residues
GLRKMGIGARLTFAFSLVVLLLAAVAAVGVSALGSMNDAMHMAVEKRLLRVIDLNHAKAQVLTIGLMVRDAALTEDAALV
TANAAKIARFREEIDATLEPIGKTLVASGNAEWKAVFEQLTQARATYDGQLDLVMRQLGAGEYDGARAGLTATLPSSQAA
YFDKLDAIAQLGQKLAVEAVEDATARYAFTRNLLIGMAALAAIIAALLGIGMTRSVTRPARQALDAAEALEQGQLAHTIE
VRSQDEMGRMLGALERAFGQLGTLVRGIQHAAGSIDTAAREISSGNTDLSRRTEQQAASLEQTAASMEQLTSTVRQNAEN
ARQANQLAANASDVATEGGRVVRSVVDTMDGITQSSARVAEIIGVIEGIAFQTNILALNAAVEAARAGEQGRGFSVVAAE
VRSLAQRSSSAAKEIGDLINGSVRQVKEGARQVEVAGKTMDDIVGAVRRVTDIMGEITAASEEQSAGIEQVGLAIAQMET
VTQQNAALVEEASAAAESLMQQAGGLVTEVARFDLGQQQQREVPRAPGPVAVVAQPVQPAPRLPAAAPKALTPRPSPQKA
LTQKVSTQKVSTQKVSTQKVSTQTAAAAPQRPVQPSHQLRAPAVPAAVRPPVVRKTSAAPVLARQPATPAKARQPVTHQR
KEPVLATPSSRRPVAKARPSAAPVPATADGGDWETF

Specific function: Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment, transduce a signal from the outside to the inside of the cell, and facilitate sensory adaptation through the variation of the level of

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI2367378, Length=428, Percent_Identity=50.4672897196262, Blast_Score=318, Evalue=9e-88,
Organism=Escherichia coli, GI1788195, Length=390, Percent_Identity=48.974358974359, Blast_Score=297, Evalue=1e-81,
Organism=Escherichia coli, GI1787690, Length=374, Percent_Identity=49.7326203208556, Blast_Score=295, Evalue=8e-81,
Organism=Escherichia coli, GI1788194, Length=377, Percent_Identity=48.2758620689655, Blast_Score=280, Evalue=2e-76,
Organism=Escherichia coli, GI1789453, Length=302, Percent_Identity=40.0662251655629, Blast_Score=210, Evalue=3e-55,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR003122
- InterPro:   IPR004091
- InterPro:   IPR004089
- InterPro:   IPR003660 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal; PF02203 TarH [H]

EC number: NA

Molecular weight: Translated: 70866; Mature: 70734

Theoretical pI: Translated: 9.90; Mature: 9.90

Prosite motif: PS50885 HAMP ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGLRKMGIGARLTFAFSLVVLLLAAVAAVGVSALGSMNDAMHMAVEKRLLRVIDLNHAKA
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHH
QVLTIGLMVRDAALTEDAALVTANAAKIARFREEIDATLEPIGKTLVASGNAEWKAVFEQ
HHHHHHHHHHHHHHCCCCHHEECHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHH
LTQARATYDGQLDLVMRQLGAGEYDGARAGLTATLPSSQAAYFDKLDAIAQLGQKLAVEA
HHHHHHCCCCHHHHHHHHHCCCCCCCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHH
VEDATARYAFTRNLLIGMAALAAIIAALLGIGMTRSVTRPARQALDAAEALEQGQLAHTI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCEEHE
EVRSQDEMGRMLGALERAFGQLGTLVRGIQHAAGSIDTAAREISSGNTDLSRRTEQQAAS
ECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCHHHHHHHHHHHH
LEQTAASMEQLTSTVRQNAENARQANQLAANASDVATEGGRVVRSVVDTMDGITQSSARV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHH
AEIIGVIEGIAFQTNILALNAAVEAARAGEQGRGFSVVAAEVRSLAQRSSSAAKEIGDLI
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
NGSVRQVKEGARQVEVAGKTMDDIVGAVRRVTDIMGEITAASEEQSAGIEQVGLAIAQME
CCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCHHHCCHHHHHHHHHHHH
TVTQQNAALVEEASAAAESLMQQAGGLVTEVARFDLGQQQQREVPRAPGPVAVVAQPVQP
HHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCHHHHCCCCCCCCEEEEECCCCC
APRLPAAAPKALTPRPSPQKALTQKVSTQKVSTQKVSTQKVSTQTAAAAPQRPVQPSHQL
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHC
RAPAVPAAVRPPVVRKTSAAPVLARQPATPAKARQPVTHQRKEPVLATPSSRRPVAKARP
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHCCCCHHHCCCCCEECCCCCCCHHHCCC
SAAPVPATADGGDWETF
CCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
GLRKMGIGARLTFAFSLVVLLLAAVAAVGVSALGSMNDAMHMAVEKRLLRVIDLNHAKA
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHH
QVLTIGLMVRDAALTEDAALVTANAAKIARFREEIDATLEPIGKTLVASGNAEWKAVFEQ
HHHHHHHHHHHHHHCCCCHHEECHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHH
LTQARATYDGQLDLVMRQLGAGEYDGARAGLTATLPSSQAAYFDKLDAIAQLGQKLAVEA
HHHHHHCCCCHHHHHHHHHCCCCCCCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHH
VEDATARYAFTRNLLIGMAALAAIIAALLGIGMTRSVTRPARQALDAAEALEQGQLAHTI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCEEHE
EVRSQDEMGRMLGALERAFGQLGTLVRGIQHAAGSIDTAAREISSGNTDLSRRTEQQAAS
ECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCHHHHHHHHHHHH
LEQTAASMEQLTSTVRQNAENARQANQLAANASDVATEGGRVVRSVVDTMDGITQSSARV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHH
AEIIGVIEGIAFQTNILALNAAVEAARAGEQGRGFSVVAAEVRSLAQRSSSAAKEIGDLI
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
NGSVRQVKEGARQVEVAGKTMDDIVGAVRRVTDIMGEITAASEEQSAGIEQVGLAIAQME
CCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCHHHCCHHHHHHHHHHHH
TVTQQNAALVEEASAAAESLMQQAGGLVTEVARFDLGQQQQREVPRAPGPVAVVAQPVQP
HHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCHHHHCCCCCCCCEEEEECCCCC
APRLPAAAPKALTPRPSPQKALTQKVSTQKVSTQKVSTQKVSTQTAAAAPQRPVQPSHQL
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHC
RAPAVPAAVRPPVVRKTSAAPVLARQPATPAKARQPVTHQRKEPVLATPSSRRPVAKARP
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHCCCCHHHCCCCCEECCCCCCCHHHCCC
SAAPVPATADGGDWETF
CCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 6402709; 7610040; 9278503; 8384293; 6213619; 2033064; 10466731 [H]