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The map label for this gene is ycgM [C]

Identifier: 94314118

GI number: 94314118

Start: 1894502

End: 1895440

Strand: Direct

Name: ycgM [C]

Synonym: Rmet_5199

Alternate gene names: 94314118

Gene position: 1894502-1895440 (Clockwise)

Preceding gene: 94314116

Following gene: 94314119

Centisome position: 73.43

GC content: 64.64

Gene sequence:

>939_bases
ATGGTGAATTGGTATAGCCTCGCCACTTTTGAACTTGCCGGTCGGCAGCAGCCCGGCCTGGTCGTTGAGAACACGCTCTA
TGCGCTGGCCGATGTGGGCCAGGCGTGCGGCATCGAGGCATCGCGCCTGCCGCAGGACCTGAATGCGGCACTGGCGGACT
GGTCGCGCCATGCGCCGCTGCTGGCCGACGCCGCCGCACGTATTCCCGCATTGCGCGCGGCTGGCAAGCTCGCCGCGGTG
GACGCCGCCGCCACCTATGCGGCGCCCTATCGGCCACGCCGGATCTTTGGCACCGCCTCAAACTTCTACGAGCACGCGGA
CGAGATGGGCACCAAGCTGGCTGCCCGCAGCGAAAGCCAGCCCTACATATTCATGAAGGCTGAAACCAGCGTGGTGGCCA
CCGGCACCACGGTGCTGATGCCGCCGGAAACCAAGAAACTCGACTGGGAAGTGGAGCTGGGCGTAGTGATTGGCCAGGCA
TGCCGCCATGTCAGCGTGGAGGACGCGCTGTCGGTGATCGCCGGCTATACCGTGTTCAACGACATCAGCGCGCGTGACCT
GAACCGCCGCACCGACTATCCGTTCACGCACGACTGGTTCCGCGGCAAGAGCTTCGATACCTTCGGCCCGATGGGCCCGT
GGCTTGTGCCCGCGACCTGCATTCCCAATCCGCAGAACCTGCGCATGACGCTGCATGTCAACGGCGAGGTCATGCAGAAC
GGCAACACCTCGCAAATGATCTTCTCGGTGGCCGAGCAGATCGCCTACCTGTCGCGTATTCTGACGCTGCAACCTGGCGA
CCTTATCGCCACGGGCACGCCGGACGGTGTGGGCATGGGGCGTGGACTCTTCCTGAAGCCTGGCGACAGCATGACGGCCT
GGGTCGAGCAGATCGGCACGATCGAGAACCGCGTCGCGCTGGAACCGAACGCACGCTAG

Upstream 100 bases:

>100_bases
AAAATAAAGTATTCACAAACGCGGATGTGCATAAAACGAATCGGGAGACCGAATACGTGCTGCGCATACCAACTTTGTCC
GACAACACCAAACAGGAGAC

Downstream 100 bases:

>100_bases
CCACGCGCCGGCCACAGCCCGCTTCGCCAGGCAAACCAGGCAGGAGACAATCACATGACCCCCATTCGAACCCGCAAGCT
GGGCCACCTCGTCCTGATGG

Product: fumarylacetoacetate (FAA) hydrolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 312; Mature: 312

Protein sequence:

>312_residues
MVNWYSLATFELAGRQQPGLVVENTLYALADVGQACGIEASRLPQDLNAALADWSRHAPLLADAAARIPALRAAGKLAAV
DAAATYAAPYRPRRIFGTASNFYEHADEMGTKLAARSESQPYIFMKAETSVVATGTTVLMPPETKKLDWEVELGVVIGQA
CRHVSVEDALSVIAGYTVFNDISARDLNRRTDYPFTHDWFRGKSFDTFGPMGPWLVPATCIPNPQNLRMTLHVNGEVMQN
GNTSQMIFSVAEQIAYLSRILTLQPGDLIATGTPDGVGMGRGLFLKPGDSMTAWVEQIGTIENRVALEPNAR

Sequences:

>Translated_312_residues
MVNWYSLATFELAGRQQPGLVVENTLYALADVGQACGIEASRLPQDLNAALADWSRHAPLLADAAARIPALRAAGKLAAV
DAAATYAAPYRPRRIFGTASNFYEHADEMGTKLAARSESQPYIFMKAETSVVATGTTVLMPPETKKLDWEVELGVVIGQA
CRHVSVEDALSVIAGYTVFNDISARDLNRRTDYPFTHDWFRGKSFDTFGPMGPWLVPATCIPNPQNLRMTLHVNGEVMQN
GNTSQMIFSVAEQIAYLSRILTLQPGDLIATGTPDGVGMGRGLFLKPGDSMTAWVEQIGTIENRVALEPNAR
>Mature_312_residues
MVNWYSLATFELAGRQQPGLVVENTLYALADVGQACGIEASRLPQDLNAALADWSRHAPLLADAAARIPALRAAGKLAAV
DAAATYAAPYRPRRIFGTASNFYEHADEMGTKLAARSESQPYIFMKAETSVVATGTTVLMPPETKKLDWEVELGVVIGQA
CRHVSVEDALSVIAGYTVFNDISARDLNRRTDYPFTHDWFRGKSFDTFGPMGPWLVPATCIPNPQNLRMTLHVNGEVMQN
GNTSQMIFSVAEQIAYLSRILTLQPGDLIATGTPDGVGMGRGLFLKPGDSMTAWVEQIGTIENRVALEPNAR

Specific function: Unknown

COG id: COG0179

COG function: function code Q; 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FAH family [H]

Homologues:

Organism=Homo sapiens, GI156231349, Length=228, Percent_Identity=40.7894736842105, Blast_Score=189, Evalue=4e-48,
Organism=Homo sapiens, GI40786394, Length=229, Percent_Identity=40.6113537117904, Blast_Score=184, Evalue=1e-46,
Organism=Homo sapiens, GI66348062, Length=189, Percent_Identity=39.1534391534392, Blast_Score=136, Evalue=2e-32,
Organism=Homo sapiens, GI215422413, Length=189, Percent_Identity=39.1534391534392, Blast_Score=136, Evalue=3e-32,
Organism=Homo sapiens, GI13654274, Length=189, Percent_Identity=39.1534391534392, Blast_Score=135, Evalue=3e-32,
Organism=Escherichia coli, GI1787428, Length=206, Percent_Identity=33.9805825242718, Blast_Score=120, Evalue=9e-29,
Organism=Caenorhabditis elegans, GI17557057, Length=187, Percent_Identity=35.8288770053476, Blast_Score=122, Evalue=2e-28,
Organism=Saccharomyces cerevisiae, GI6324161, Length=239, Percent_Identity=25.5230125523013, Blast_Score=80, Evalue=3e-16,
Organism=Drosophila melanogaster, GI28572127, Length=273, Percent_Identity=34.7985347985348, Blast_Score=147, Evalue=1e-35,
Organism=Drosophila melanogaster, GI24663695, Length=217, Percent_Identity=35.9447004608295, Blast_Score=133, Evalue=2e-31,
Organism=Drosophila melanogaster, GI28571789, Length=186, Percent_Identity=38.1720430107527, Blast_Score=125, Evalue=3e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002529
- InterPro:   IPR011234 [H]

Pfam domain/function: PF01557 FAA_hydrolase [H]

EC number: NA

Molecular weight: Translated: 33916; Mature: 33916

Theoretical pI: Translated: 5.37; Mature: 5.37

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVNWYSLATFELAGRQQPGLVVENTLYALADVGQACGIEASRLPQDLNAALADWSRHAPL
CCEEEEEEEEEECCCCCCCEEEHHHHHHHHHHHHHHCCCHHHCCHHHHHHHHHHHHCCCH
LADAAARIPALRAAGKLAAVDAAATYAAPYRPRRIFGTASNFYEHADEMGTKLAARSESQ
HHHHHHHCHHHHHCCCEEEHHHHHHHCCCCCCCEEEECHHHHHHHHHHHHHHHHHCCCCC
PYIFMKAETSVVATGTTVLMPPETKKLDWEVELGVVIGQACRHVSVEDALSVIAGYTVFN
CEEEEEECCEEEECCEEEEECCCCCCEEEEEEEHHHHHHHHHCCCHHHHHHHHHHHHHHC
DISARDLNRRTDYPFTHDWFRGKSFDTFGPMGPWLVPATCIPNPQNLRMTLHVNGEVMQN
CCCHHHCCCCCCCCCCCHHHCCCCCCCCCCCCCCEEEEECCCCCCCEEEEEEECCEEEEC
GNTSQMIFSVAEQIAYLSRILTLQPGDLIATGTPDGVGMGRGLFLKPGDSMTAWVEQIGT
CCHHHHHHHHHHHHHHHHHHHEECCCCEEEECCCCCCCCCCEEEECCCCHHHHHHHHHCC
IENRVALEPNAR
CCCEEEECCCCC
>Mature Secondary Structure
MVNWYSLATFELAGRQQPGLVVENTLYALADVGQACGIEASRLPQDLNAALADWSRHAPL
CCEEEEEEEEEECCCCCCCEEEHHHHHHHHHHHHHHCCCHHHCCHHHHHHHHHHHHCCCH
LADAAARIPALRAAGKLAAVDAAATYAAPYRPRRIFGTASNFYEHADEMGTKLAARSESQ
HHHHHHHCHHHHHCCCEEEHHHHHHHCCCCCCCEEEECHHHHHHHHHHHHHHHHHCCCCC
PYIFMKAETSVVATGTTVLMPPETKKLDWEVELGVVIGQACRHVSVEDALSVIAGYTVFN
CEEEEEECCEEEECCEEEEECCCCCCEEEEEEEHHHHHHHHHCCCHHHHHHHHHHHHHHC
DISARDLNRRTDYPFTHDWFRGKSFDTFGPMGPWLVPATCIPNPQNLRMTLHVNGEVMQN
CCCHHHCCCCCCCCCCCHHHCCCCCCCCCCCCCCEEEEECCCCCCCEEEEEEECCEEEEC
GNTSQMIFSVAEQIAYLSRILTLQPGDLIATGTPDGVGMGRGLFLKPGDSMTAWVEQIGT
CCHHHHHHHHHHHHHHHHHHHEECCCCEEEECCCCCCCCCCEEEECCCCHHHHHHHHHCC
IENRVALEPNAR
CCCEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12622808 [H]