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The map label for this gene is ytnA [H]

Identifier: 94314110

GI number: 94314110

Start: 1885145

End: 1886572

Strand: Reverse

Name: ytnA [H]

Synonym: Rmet_5191

Alternate gene names: 94314110

Gene position: 1886572-1885145 (Counterclockwise)

Preceding gene: 94314111

Following gene: 94314109

Centisome position: 73.12

GC content: 63.66

Gene sequence:

>1428_bases
ATGAGGCAGCAACAGGGATTCGACGCAATCGTCGAGCGGGAGCAGGGGCTGCATCGGGGGCTGTCCACGGGACAGCTCTC
CATGATCGCCATCGGCGGCGCGATCGGTACCGGCCTGTTCCTGGGGAGCGGGTTTGCCATCGGCTTCGCCGGCCCGAGCG
TGCTGGTGAGCTACGCCATCGGGGCGTTGATTGCCTTGCTGCTGATGGGCTGCCTGGCCGAGATGACGGTGGCGCATCCG
ACTTCCGGCTCGTTCGGCGCCAATGCGGAGCATTACATCGGGCCGCTGGCCGGATTCCTGGTGCGCTATGCCTACTGGTC
GTCGATCGTATTCGCGGTCGGCACGGAAGTCACGGCCATCGCGGTCTACATGAAGTACTGGTTCCCGATGGTGCCCGGGT
GGTACTGGATCGTCGGCTTCTCTGCTGCGCTGATCGGCATCAACGCCACCAGTGTCAAAGTGTTCGGCGCGGTCGAATAT
GTGTTCTCGATGCTGAAAATTGTCGCCATCGTCGGCTTTATCCTGCTCGGCGCCTATGTGGTGACACGCGCGCCGACCGG
GTCCGGCATCGGGCTGGCCAACTACACCGCACATGGTGGCTTCTTCCCGAAAGGGATGTGGGGTACTTGGGTGGCGGTGA
TCGTGTCCATCTTCAGCTACCTGAGCATCGAGATGATTGCCGTGGCGGCAGGCGAGGCACGCGACCCGGAGACCGCCATC
ACGCGCGCATTTCGCGCGACCATGGTGCGTCTGGTGTTCTTCTACCTGCTGACGCTCGCGCTGATGCTGATGATCGTGCC
GTGGACGGCGGCCGGCGCCGGCGAAAGTCCGTTCGTCAGGGTGATGGCGGCCACGCGCGTACCGGGTGCCGCAGCGGTGT
TCAACTTCGTGATTCTGGTGGCGGCGTTGTCTGCCATGAACAGCCAGCTCTATATCACCACACGGATGATGTTCAGCCTG
TCCCGCGCGGGTTACGCGCCAAAGGCGCTGGGGCAGGTCAACGGTCGCGGCGTGCCCATGACGGCGTTGTTGTTGTCCAC
CGTTGGCATCGCCTTCGCGGTGGTGCTCAACGTGGTGTATCCGGATGCCTCGTTCATGCTGATGATGGCGATCTCGATGT
TCGGTGCGATGTTCACCTGGCTGATGATCTTCATTACACATCTGTTCTTTCGGCGGCAACACCGGGGGCGGCCGCTCGCC
TTCAGGATGTGGGGCTTTCCGGTGACAACGCTGCTCGGCGCGGGGCTGATGTTCGCCACCCTGGTGACAACGTGGTTCAC
GCCGGAGTTCAGGATGACCCTGGTGGCGGGCGTGCCTTTCATGCTGGCGCTGTCGGCGGCCTACTGGCTCTGGTACCGGA
AGCGCGGCGGTGCAGCACAAGGGGACGGGGAAGACGCCGGGCGCGCGGAGGTGCGCAACAGCTGGTAA

Upstream 100 bases:

>100_bases
AAGGACATCGTCACAAGCGAGGCGTGGAACACGGAAGCGTTCCGCACGCGCAAGTCAGTGACCTGAGTGCAACGGCCAGA
ACAATAAGAGGAGACAAGCG

Downstream 100 bases:

>100_bases
CAGTCGAATCTGCTGACGGCCTCCATGCAATGAATACTGTTTCTTATTGGTGTATACACGAACTTCAAATATGAGTTCGT
TTGTGAGAAACTGTACTCAT

Product: amino acid permease

Products: Proton [Cytoplasm]; L-phenylalanine [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 475; Mature: 475

Protein sequence:

>475_residues
MRQQQGFDAIVEREQGLHRGLSTGQLSMIAIGGAIGTGLFLGSGFAIGFAGPSVLVSYAIGALIALLLMGCLAEMTVAHP
TSGSFGANAEHYIGPLAGFLVRYAYWSSIVFAVGTEVTAIAVYMKYWFPMVPGWYWIVGFSAALIGINATSVKVFGAVEY
VFSMLKIVAIVGFILLGAYVVTRAPTGSGIGLANYTAHGGFFPKGMWGTWVAVIVSIFSYLSIEMIAVAAGEARDPETAI
TRAFRATMVRLVFFYLLTLALMLMIVPWTAAGAGESPFVRVMAATRVPGAAAVFNFVILVAALSAMNSQLYITTRMMFSL
SRAGYAPKALGQVNGRGVPMTALLLSTVGIAFAVVLNVVYPDASFMLMMAISMFGAMFTWLMIFITHLFFRRQHRGRPLA
FRMWGFPVTTLLGAGLMFATLVTTWFTPEFRMTLVAGVPFMLALSAAYWLWYRKRGGAAQGDGEDAGRAEVRNSW

Sequences:

>Translated_475_residues
MRQQQGFDAIVEREQGLHRGLSTGQLSMIAIGGAIGTGLFLGSGFAIGFAGPSVLVSYAIGALIALLLMGCLAEMTVAHP
TSGSFGANAEHYIGPLAGFLVRYAYWSSIVFAVGTEVTAIAVYMKYWFPMVPGWYWIVGFSAALIGINATSVKVFGAVEY
VFSMLKIVAIVGFILLGAYVVTRAPTGSGIGLANYTAHGGFFPKGMWGTWVAVIVSIFSYLSIEMIAVAAGEARDPETAI
TRAFRATMVRLVFFYLLTLALMLMIVPWTAAGAGESPFVRVMAATRVPGAAAVFNFVILVAALSAMNSQLYITTRMMFSL
SRAGYAPKALGQVNGRGVPMTALLLSTVGIAFAVVLNVVYPDASFMLMMAISMFGAMFTWLMIFITHLFFRRQHRGRPLA
FRMWGFPVTTLLGAGLMFATLVTTWFTPEFRMTLVAGVPFMLALSAAYWLWYRKRGGAAQGDGEDAGRAEVRNSW
>Mature_475_residues
MRQQQGFDAIVEREQGLHRGLSTGQLSMIAIGGAIGTGLFLGSGFAIGFAGPSVLVSYAIGALIALLLMGCLAEMTVAHP
TSGSFGANAEHYIGPLAGFLVRYAYWSSIVFAVGTEVTAIAVYMKYWFPMVPGWYWIVGFSAALIGINATSVKVFGAVEY
VFSMLKIVAIVGFILLGAYVVTRAPTGSGIGLANYTAHGGFFPKGMWGTWVAVIVSIFSYLSIEMIAVAAGEARDPETAI
TRAFRATMVRLVFFYLLTLALMLMIVPWTAAGAGESPFVRVMAATRVPGAAAVFNFVILVAALSAMNSQLYITTRMMFSL
SRAGYAPKALGQVNGRGVPMTALLLSTVGIAFAVVLNVVYPDASFMLMMAISMFGAMFTWLMIFITHLFFRRQHRGRPLA
FRMWGFPVTTLLGAGLMFATLVTTWFTPEFRMTLVAGVPFMLALSAAYWLWYRKRGGAAQGDGEDAGRAEVRNSW

Specific function: Permease That Is Involved In The Transport Across The Cytoplasmic Membrane Of Phenylalanine. [C]

COG id: COG1113

COG function: function code E; Gamma-aminobutyrate permease and related permeases

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the amino acid-polyamine-organocation (APC) superfamily [H]

Homologues:

Organism=Escherichia coli, GI1786789, Length=428, Percent_Identity=38.0841121495327, Blast_Score=296, Evalue=3e-81,
Organism=Escherichia coli, GI87081708, Length=449, Percent_Identity=38.5300668151448, Blast_Score=285, Evalue=5e-78,
Organism=Escherichia coli, GI1786302, Length=419, Percent_Identity=36.9928400954654, Blast_Score=278, Evalue=7e-76,
Organism=Escherichia coli, GI1786602, Length=454, Percent_Identity=35.0220264317181, Blast_Score=267, Evalue=1e-72,
Organism=Escherichia coli, GI1790653, Length=403, Percent_Identity=34.4913151364764, Blast_Score=256, Evalue=2e-69,
Organism=Escherichia coli, GI48994972, Length=460, Percent_Identity=33.4782608695652, Blast_Score=256, Evalue=3e-69,
Organism=Escherichia coli, GI87081915, Length=470, Percent_Identity=31.4893617021277, Blast_Score=236, Evalue=2e-63,
Organism=Escherichia coli, GI1789017, Length=429, Percent_Identity=32.8671328671329, Blast_Score=233, Evalue=2e-62,
Organism=Escherichia coli, GI1788480, Length=411, Percent_Identity=34.7931873479319, Blast_Score=206, Evalue=2e-54,
Organism=Saccharomyces cerevisiae, GI6324990, Length=414, Percent_Identity=31.4009661835749, Blast_Score=176, Evalue=8e-45,
Organism=Saccharomyces cerevisiae, GI6321629, Length=412, Percent_Identity=29.126213592233, Blast_Score=173, Evalue=6e-44,
Organism=Saccharomyces cerevisiae, GI6324061, Length=412, Percent_Identity=29.126213592233, Blast_Score=170, Evalue=6e-43,
Organism=Saccharomyces cerevisiae, GI6320772, Length=508, Percent_Identity=26.9685039370079, Blast_Score=166, Evalue=8e-42,
Organism=Saccharomyces cerevisiae, GI6324553, Length=427, Percent_Identity=29.03981264637, Blast_Score=165, Evalue=2e-41,
Organism=Saccharomyces cerevisiae, GI6324924, Length=465, Percent_Identity=29.6774193548387, Blast_Score=164, Evalue=2e-41,
Organism=Saccharomyces cerevisiae, GI6324059, Length=412, Percent_Identity=31.0679611650485, Blast_Score=159, Evalue=9e-40,
Organism=Saccharomyces cerevisiae, GI6322892, Length=423, Percent_Identity=29.5508274231678, Blast_Score=152, Evalue=1e-37,
Organism=Saccharomyces cerevisiae, GI6319824, Length=406, Percent_Identity=28.3251231527094, Blast_Score=144, Evalue=4e-35,
Organism=Saccharomyces cerevisiae, GI6320251, Length=406, Percent_Identity=27.0935960591133, Blast_Score=144, Evalue=4e-35,
Organism=Saccharomyces cerevisiae, GI6320717, Length=416, Percent_Identity=26.4423076923077, Blast_Score=140, Evalue=3e-34,
Organism=Saccharomyces cerevisiae, GI6319542, Length=422, Percent_Identity=26.5402843601896, Blast_Score=139, Evalue=1e-33,
Organism=Saccharomyces cerevisiae, GI6319543, Length=393, Percent_Identity=26.972010178117, Blast_Score=134, Evalue=3e-32,
Organism=Saccharomyces cerevisiae, GI6321053, Length=434, Percent_Identity=26.7281105990783, Blast_Score=129, Evalue=8e-31,
Organism=Saccharomyces cerevisiae, GI6319608, Length=427, Percent_Identity=26.6978922716628, Blast_Score=126, Evalue=7e-30,
Organism=Saccharomyces cerevisiae, GI6322967, Length=394, Percent_Identity=27.6649746192893, Blast_Score=120, Evalue=4e-28,
Organism=Saccharomyces cerevisiae, GI6324981, Length=394, Percent_Identity=28.1725888324873, Blast_Score=113, Evalue=6e-26,
Organism=Saccharomyces cerevisiae, GI6320364, Length=423, Percent_Identity=22.6950354609929, Blast_Score=72, Evalue=2e-13,
Organism=Drosophila melanogaster, GI221512776, Length=425, Percent_Identity=22.5882352941176, Blast_Score=66, Evalue=6e-11,
Organism=Drosophila melanogaster, GI24666159, Length=426, Percent_Identity=22.5352112676056, Blast_Score=65, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004841
- InterPro:   IPR002293
- InterPro:   IPR004840 [H]

Pfam domain/function: PF00324 AA_permease [H]

EC number: NA

Molecular weight: Translated: 51222; Mature: 51222

Theoretical pI: Translated: 10.14; Mature: 10.14

Prosite motif: PS00218 AMINO_ACID_PERMEASE_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
5.7 %Met     (Translated Protein)
5.9 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
5.7 %Met     (Mature Protein)
5.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRQQQGFDAIVEREQGLHRGLSTGQLSMIAIGGAIGTGLFLGSGFAIGFAGPSVLVSYAI
CCCCCCHHHHHHHHHHHHCCCCCCCEEEEEECHHHHHHHHHCCCCEEECCCHHHHHHHHH
GALIALLLMGCLAEMTVAHPTSGSFGANAEHYIGPLAGFLVRYAYWSSIVFAVGTEVTAI
HHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHH
AVYMKYWFPMVPGWYWIVGFSAALIGINATSVKVFGAVEYVFSMLKIVAIVGFILLGAYV
HHHHHHHHHHCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VTRAPTGSGIGLANYTAHGGFFPKGMWGTWVAVIVSIFSYLSIEMIAVAAGEARDPETAI
HHCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCHHHH
TRAFRATMVRLVFFYLLTLALMLMIVPWTAAGAGESPFVRVMAATRVPGAAAVFNFVILV
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEHHCCCHHHHHHHHHHHH
AALSAMNSQLYITTRMMFSLSRAGYAPKALGQVNGRGVPMTALLLSTVGIAFAVVLNVVY
HHHHHCCCCEEEHHHHHHHHHHCCCCCHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHC
PDASFMLMMAISMFGAMFTWLMIFITHLFFRRQHRGRPLAFRMWGFPVTTLLGAGLMFAT
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHHH
LVTTWFTPEFRMTLVAGVPFMLALSAAYWLWYRKRGGAAQGDGEDAGRAEVRNSW
HHHHHCCCHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MRQQQGFDAIVEREQGLHRGLSTGQLSMIAIGGAIGTGLFLGSGFAIGFAGPSVLVSYAI
CCCCCCHHHHHHHHHHHHCCCCCCCEEEEEECHHHHHHHHHCCCCEEECCCHHHHHHHHH
GALIALLLMGCLAEMTVAHPTSGSFGANAEHYIGPLAGFLVRYAYWSSIVFAVGTEVTAI
HHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHH
AVYMKYWFPMVPGWYWIVGFSAALIGINATSVKVFGAVEYVFSMLKIVAIVGFILLGAYV
HHHHHHHHHHCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VTRAPTGSGIGLANYTAHGGFFPKGMWGTWVAVIVSIFSYLSIEMIAVAAGEARDPETAI
HHCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCHHHH
TRAFRATMVRLVFFYLLTLALMLMIVPWTAAGAGESPFVRVMAATRVPGAAAVFNFVILV
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEHHCCCHHHHHHHHHHHH
AALSAMNSQLYITTRMMFSLSRAGYAPKALGQVNGRGVPMTALLLSTVGIAFAVVLNVVY
HHHHHCCCCEEEHHHHHHHHHHCCCCCHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHC
PDASFMLMMAISMFGAMFTWLMIFITHLFFRRQHRGRPLAFRMWGFPVTTLLGAGLMFAT
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHHH
LVTTWFTPEFRMTLVAGVPFMLALSAAYWLWYRKRGGAAQGDGEDAGRAEVRNSW
HHHHHCCCHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; L-phenylalanine [Periplasm] [C]

Specific reaction: Proton [Periplasm] + L-phenylalanine [Periplasm] = Proton [Cytoplasm] + L-phenylalanine [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9387221; 9384377 [H]