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The map label for this gene is cynT [H]

Identifier: 94314104

GI number: 94314104

Start: 1878859

End: 1879536

Strand: Direct

Name: cynT [H]

Synonym: Rmet_5185

Alternate gene names: 94314104

Gene position: 1878859-1879536 (Clockwise)

Preceding gene: 291481560

Following gene: 94314105

Centisome position: 72.82

GC content: 58.41

Gene sequence:

>678_bases
ATGCGCAAACTCATAATGGGCATTGTGGAATTTCGCGAGAAGATGCTACCGCGGTACGCAGAACAGTTCAGCAAGCTCGC
GCTCGCGCAAACGCCTGATGCGCTCTTCATCACGTGCTCGGATAGTCGGGTTGTTCCGGACCTGCTCGCATCGACGCATC
CCGGCGATCTTTTTACGATGCGCAACGTTGGCAATCTGATACCCCCTGCAACCGCGGAAGGGGTCTCGACCGGCGATCTC
TCCGAGGCAAGCGCAATCGAGTACGCGGTGTTGGTGCTAAAGGTCGCGAATATTGTCGTGTGTGGGCATTCCGAATGCGG
CGCTATGAAAGCGGTCTATTCACGCAACCCGAAGCTGAAAGCACCAAATCTTGATAAATGGCTTTACCACGCCAGCAACG
CGGCGTTCCGCCTCGAACACGAGGGTGCGCTCGATGAAAGCCTGAAGCCGCACGACCAGCTGTCACAACTCAATGTCCTC
GTGCAGATCGAACATCTGATGACTTACCCGATCGTACGCCGGCAAGTTATGGCCGGGGCGTTGGTATTAAGCGGCTGGTG
GTTCGACATAGCGACCGGCGACATGTACGCCTATGAGCGGGCGAGCCGTTCGTTCGAGGTCATTGACCGCGCGCTGGCCG
AGCGGCTTGCTTCGCGCCTTGCCTCGCGCGCGCGGTGA

Upstream 100 bases:

>100_bases
ACTGGCGCACAGCGGCCTGGGCCATGACTGAGGCTCACACGTACCCGGGTCTAGCGAGGAGCGGAAGAATTGTCAGGCTC
AACAATGTCGGCAGCACGTC

Downstream 100 bases:

>100_bases
GGGCCGGGACGATATCAGGATGGCCATCCGTACCACGCGCGACGCGCTCTCTCGCATTTTCTACCAGCGCTGTTTCTGGC
TCTTTGTGGTGTTGCTCACG

Product: carbonic anhydrase

Products: NA

Alternate protein names: Carbonate dehydratase [H]

Number of amino acids: Translated: 225; Mature: 225

Protein sequence:

>225_residues
MRKLIMGIVEFREKMLPRYAEQFSKLALAQTPDALFITCSDSRVVPDLLASTHPGDLFTMRNVGNLIPPATAEGVSTGDL
SEASAIEYAVLVLKVANIVVCGHSECGAMKAVYSRNPKLKAPNLDKWLYHASNAAFRLEHEGALDESLKPHDQLSQLNVL
VQIEHLMTYPIVRRQVMAGALVLSGWWFDIATGDMYAYERASRSFEVIDRALAERLASRLASRAR

Sequences:

>Translated_225_residues
MRKLIMGIVEFREKMLPRYAEQFSKLALAQTPDALFITCSDSRVVPDLLASTHPGDLFTMRNVGNLIPPATAEGVSTGDL
SEASAIEYAVLVLKVANIVVCGHSECGAMKAVYSRNPKLKAPNLDKWLYHASNAAFRLEHEGALDESLKPHDQLSQLNVL
VQIEHLMTYPIVRRQVMAGALVLSGWWFDIATGDMYAYERASRSFEVIDRALAERLASRLASRAR
>Mature_225_residues
MRKLIMGIVEFREKMLPRYAEQFSKLALAQTPDALFITCSDSRVVPDLLASTHPGDLFTMRNVGNLIPPATAEGVSTGDL
SEASAIEYAVLVLKVANIVVCGHSECGAMKAVYSRNPKLKAPNLDKWLYHASNAAFRLEHEGALDESLKPHDQLSQLNVL
VQIEHLMTYPIVRRQVMAGALVLSGWWFDIATGDMYAYERASRSFEVIDRALAERLASRLASRAR

Specific function: Reversible Hydration Of Carbon Dioxide. Carbon Dioxide Formed In The Bicarbonate-Dependent Decomposition Of Cyanate By Cyanase (Cyns) Diffuses Out Of The Cell Faster Than It Would Be Hydrated To Bicarbonate, So The Apparent Function Of This Enzyme Is To C

COG id: COG0288

COG function: function code P; Carbonic anhydrase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the beta-class carbonic anhydrase family [H]

Homologues:

Organism=Escherichia coli, GI1786534, Length=212, Percent_Identity=38.2075471698113, Blast_Score=154, Evalue=5e-39,
Organism=Escherichia coli, GI1786318, Length=174, Percent_Identity=37.9310344827586, Blast_Score=98, Evalue=4e-22,
Organism=Caenorhabditis elegans, GI115532990, Length=247, Percent_Identity=29.9595141700405, Blast_Score=131, Evalue=3e-31,
Organism=Caenorhabditis elegans, GI25147564, Length=256, Percent_Identity=30.078125, Blast_Score=127, Evalue=6e-30,
Organism=Saccharomyces cerevisiae, GI6324292, Length=177, Percent_Identity=31.638418079096, Blast_Score=84, Evalue=1e-17,
Organism=Drosophila melanogaster, GI24645213, Length=254, Percent_Identity=29.9212598425197, Blast_Score=124, Evalue=3e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001765
- InterPro:   IPR015892 [H]

Pfam domain/function: PF00484 Pro_CA [H]

EC number: =4.2.1.1 [H]

Molecular weight: Translated: 24975; Mature: 24975

Theoretical pI: Translated: 7.60; Mature: 7.60

Prosite motif: PS00704 PROK_CO2_ANHYDRASE_1 ; PS00705 PROK_CO2_ANHYDRASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRKLIMGIVEFREKMLPRYAEQFSKLALAQTPDALFITCSDSRVVPDLLASTHPGDLFTM
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCHHHHHCCCCCCEEEH
RNVGNLIPPATAEGVSTGDLSEASAIEYAVLVLKVANIVVCGHSECGAMKAVYSRNPKLK
HHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHEEEECCCCHHHHHHHHCCCCCCC
APNLDKWLYHASNAAFRLEHEGALDESLKPHDQLSQLNVLVQIEHLMTYPIVRRQVMAGA
CCCHHHHHHHCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LVLSGWWFDIATGDMYAYERASRSFEVIDRALAERLASRLASRAR
HHHHCEEEEECCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MRKLIMGIVEFREKMLPRYAEQFSKLALAQTPDALFITCSDSRVVPDLLASTHPGDLFTM
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCHHHHHCCCCCCEEEH
RNVGNLIPPATAEGVSTGDLSEASAIEYAVLVLKVANIVVCGHSECGAMKAVYSRNPKLK
HHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHEEEECCCCHHHHHHHHCCCCCCC
APNLDKWLYHASNAAFRLEHEGALDESLKPHDQLSQLNVLVQIEHLMTYPIVRRQVMAGA
CCCHHHHHHHCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LVLSGWWFDIATGDMYAYERASRSFEVIDRALAERLASRLASRAR
HHHHCEEEEECCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]