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The map label for this gene is qseB [H]

Identifier: 94314049

GI number: 94314049

Start: 1827623

End: 1828294

Strand: Reverse

Name: qseB [H]

Synonym: Rmet_5130

Alternate gene names: 94314049

Gene position: 1828294-1827623 (Counterclockwise)

Preceding gene: 94314050

Following gene: 94314048

Centisome position: 70.86

GC content: 63.99

Gene sequence:

>672_bases
ATGCGCATCCTGCTGATCGAGGACGAAGCCACACTGGCGCGCCAGCTTGCCGATACGCTGTCTCAGGCAGGATATGTGGT
GGATCACGCGTCAGATGGCATCGACGCCGAGCATCTCGGTACCGAGAATCCCTATGATGCGGTCATTCTCGACCTGGGCC
TGCCCAAGCTCGATGGCCTGACCGTGCTCAAGCGTTGGCGCCAGGCCGGCAACGGCGTGCCGGTGCTGATTCTGACCGCG
CGCGACAGCTGGGTGGAGAAGGTGGAAGGCATCGACGCGGGCGCGGATGACTATCTCACCAAGCCGTTCCGTGCCGAGGA
ACTGCTGGCCCGTATTCGGGCGCTGATCCGCCGCTCCACCGGGCATACCTCGCCCGTTCTCGTCTGCGGCCCCGTCACGC
TGGCGCCCGCCACTGGTCAGGTCAGTGTGGACGGATCGCCCATCGTCCTTACCGCCCACGAGTACAAGGTGCTCGATTAC
CTGATGCACCACCAGGGTGTGATCGTCAGCAAGACCACGCTGACCGAGCATATCTACGCGCAGGACCATGACCGCGACAG
CAATACCATCGAGGTATTCGTCGGTCGCCTGCGACGCAAGCTCGGTGTCGACGTCATCGAAACGGTGCGTGGCCTCGGAT
ACCGGCTGCGCCCGCCGGAACACGGCGCATGA

Upstream 100 bases:

>100_bases
CGAACAGCGCGGTGGCCAAGCTCAAGTACGATGCCCGCAACGCGCGCCTGTTGAAGGCAAAGGGGCATGACCTCGACAAA
GCCCGCAAGCCCTGACGACG

Downstream 100 bases:

>100_bases
AGCGGCCCACCATCGCGGGCAGGTTGCTGCTGATTGCCACGCTGTGGGTGGTCGGCACGTTATGCGCCACGGGCTGGGTG
CTCGATACGCTGTTCGGGCG

Product: OmpR/winged helix family two component transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 223; Mature: 223

Protein sequence:

>223_residues
MRILLIEDEATLARQLADTLSQAGYVVDHASDGIDAEHLGTENPYDAVILDLGLPKLDGLTVLKRWRQAGNGVPVLILTA
RDSWVEKVEGIDAGADDYLTKPFRAEELLARIRALIRRSTGHTSPVLVCGPVTLAPATGQVSVDGSPIVLTAHEYKVLDY
LMHHQGVIVSKTTLTEHIYAQDHDRDSNTIEVFVGRLRRKLGVDVIETVRGLGYRLRPPEHGA

Sequences:

>Translated_223_residues
MRILLIEDEATLARQLADTLSQAGYVVDHASDGIDAEHLGTENPYDAVILDLGLPKLDGLTVLKRWRQAGNGVPVLILTA
RDSWVEKVEGIDAGADDYLTKPFRAEELLARIRALIRRSTGHTSPVLVCGPVTLAPATGQVSVDGSPIVLTAHEYKVLDY
LMHHQGVIVSKTTLTEHIYAQDHDRDSNTIEVFVGRLRRKLGVDVIETVRGLGYRLRPPEHGA
>Mature_223_residues
MRILLIEDEATLARQLADTLSQAGYVVDHASDGIDAEHLGTENPYDAVILDLGLPKLDGLTVLKRWRQAGNGVPVLILTA
RDSWVEKVEGIDAGADDYLTKPFRAEELLARIRALIRRSTGHTSPVLVCGPVTLAPATGQVSVDGSPIVLTAHEYKVLDY
LMHHQGVIVSKTTLTEHIYAQDHDRDSNTIEVFVGRLRRKLGVDVIETVRGLGYRLRPPEHGA

Specific function: Member of a two-component regulatory system qseB/qseC. Activates the flagella regulon by activating transcription of flhDC [H]

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1789402, Length=216, Percent_Identity=45.3703703703704, Blast_Score=183, Evalue=8e-48,
Organism=Escherichia coli, GI1787375, Length=218, Percent_Identity=43.1192660550459, Blast_Score=182, Evalue=1e-47,
Organism=Escherichia coli, GI1790552, Length=222, Percent_Identity=43.2432432432432, Blast_Score=163, Evalue=1e-41,
Organism=Escherichia coli, GI1786784, Length=229, Percent_Identity=36.6812227074236, Blast_Score=161, Evalue=3e-41,
Organism=Escherichia coli, GI87082012, Length=220, Percent_Identity=39.5454545454545, Blast_Score=150, Evalue=4e-38,
Organism=Escherichia coli, GI1789809, Length=229, Percent_Identity=31.8777292576419, Blast_Score=122, Evalue=3e-29,
Organism=Escherichia coli, GI1790860, Length=222, Percent_Identity=32.8828828828829, Blast_Score=121, Evalue=3e-29,
Organism=Escherichia coli, GI1786599, Length=222, Percent_Identity=33.7837837837838, Blast_Score=120, Evalue=1e-28,
Organism=Escherichia coli, GI2367329, Length=226, Percent_Identity=34.9557522123894, Blast_Score=113, Evalue=1e-26,
Organism=Escherichia coli, GI1788394, Length=221, Percent_Identity=31.6742081447964, Blast_Score=108, Evalue=2e-25,
Organism=Escherichia coli, GI1786911, Length=230, Percent_Identity=33.0434782608696, Blast_Score=106, Evalue=2e-24,
Organism=Escherichia coli, GI1787229, Length=222, Percent_Identity=29.7297297297297, Blast_Score=100, Evalue=6e-23,
Organism=Escherichia coli, GI1790863, Length=231, Percent_Identity=29.004329004329, Blast_Score=98, Evalue=5e-22,
Organism=Escherichia coli, GI145693140, Length=234, Percent_Identity=27.7777777777778, Blast_Score=71, Evalue=4e-14,
Organism=Escherichia coli, GI1788550, Length=160, Percent_Identity=30.625, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI145693157, Length=102, Percent_Identity=37.2549019607843, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI1787487, Length=116, Percent_Identity=32.7586206896552, Blast_Score=63, Evalue=1e-11,
Organism=Escherichia coli, GI1788191, Length=121, Percent_Identity=31.404958677686, Blast_Score=63, Evalue=2e-11,
Organism=Escherichia coli, GI1790437, Length=139, Percent_Identity=30.9352517985612, Blast_Score=62, Evalue=2e-11,
Organism=Escherichia coli, GI1788713, Length=125, Percent_Identity=29.6, Blast_Score=62, Evalue=4e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 24468; Mature: 24468

Theoretical pI: Translated: 6.03; Mature: 6.03

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS00217 SUGAR_TRANSPORT_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRILLIEDEATLARQLADTLSQAGYVVDHASDGIDAEHLGTENPYDAVILDLGLPKLDGL
CEEEEECCHHHHHHHHHHHHHHCCEEEECCCCCCCHHHCCCCCCCCEEEEECCCCCCCHH
TVLKRWRQAGNGVPVLILTARDSWVEKVEGIDAGADDYLTKPFRAEELLARIRALIRRST
HHHHHHHHCCCCCEEEEEECCHHHHHHHHCCCCCCHHHHCCCCCHHHHHHHHHHHHHHCC
GHTSPVLVCGPVTLAPATGQVSVDGSPIVLTAHEYKVLDYLMHHQGVIVSKTTLTEHIYA
CCCCCEEEECCEEECCCCCEEEECCCCEEEEEHHHHHHHHHHHHCCEEEEHHHHHHHHHH
QDHDRDSNTIEVFVGRLRRKLGVDVIETVRGLGYRLRPPEHGA
CCCCCCCCHHHHHHHHHHHHHCHHHHHHHHHCCEECCCCCCCC
>Mature Secondary Structure
MRILLIEDEATLARQLADTLSQAGYVVDHASDGIDAEHLGTENPYDAVILDLGLPKLDGL
CEEEEECCHHHHHHHHHHHHHHCCEEEECCCCCCCHHHCCCCCCCCEEEEECCCCCCCHH
TVLKRWRQAGNGVPVLILTARDSWVEKVEGIDAGADDYLTKPFRAEELLARIRALIRRST
HHHHHHHHCCCCCEEEEEECCHHHHHHHHCCCCCCHHHHCCCCCHHHHHHHHHHHHHHCC
GHTSPVLVCGPVTLAPATGQVSVDGSPIVLTAHEYKVLDYLMHHQGVIVSKTTLTEHIYA
CCCCCEEEECCEEECCCCCEEEECCCCEEEEEHHHHHHHHHHHHCCEEEEHHHHHHHHHH
QDHDRDSNTIEVFVGRLRRKLGVDVIETVRGLGYRLRPPEHGA
CCCCCCCCHHHHHHHHHHHHHCHHHHHHHHHCCEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11677608; 12644504 [H]