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The map label for this gene is yefC [C]

Identifier: 94314023

GI number: 94314023

Start: 1795684

End: 1796721

Strand: Direct

Name: yefC [C]

Synonym: Rmet_5104

Alternate gene names: 94314023

Gene position: 1795684-1796721 (Clockwise)

Preceding gene: 291481557

Following gene: 94314024

Centisome position: 69.6

GC content: 63.78

Gene sequence:

>1038_bases
ATGAGCACCAATACAAAGCGCTTCGACGCGCTTGTCTTTATCGGCCGTTTCCAGCCGATGCACCGTGGTCACGTTGATGT
ACTACGCCGGGCGCTGAGCCAGGCGGACACCGTTTGCATCCTGATCGGATCCACCGACAAGCCTCGCACCATCAAGGACC
CGTTCTCGTTCGACGAGCGCCGGCAAATGATCGAGTCCGTACTGGACGAATCAAGCCGCGCGCGCGTCCGGATCGGCGCG
GTACAGGATTCGACCTACAACGACAGCGACTGGGTCCGCTGGGTACAGGATGCCGTGGCAGGACTGCTCGGCGATACCGC
CGGCCGCCGGATCGGCATCATCGGTCACGAAAAGGATGGTTCTTCGTACTACCTTCGCATGTTCCCGCAATGGGAACTGG
TCGAAGCCGACAGTACCGAAGACATCTCCGCCACCGAAATCCGCGAGCAGTTCCTGGCCGAACGCAGCAACAGCTTCGTC
TCGTGGGCCGTGCCCGCGCCGGTATTCCAGTGGATGGAGCTGTTTCGCGACCGGCCCGAGTTCGCCCAGCTGAAGGCCGA
GGCGGAGTTCATCGCCGGGTACAGGAAAGCCTGGTCGGCCGCGCCGTATCCGGTAACGTTCGTCACCGTCGACGCGGTAG
TGGTCCATTCCGGCCACCTGTTGCTGGTGCGCCGGCGCAGCGAGCCGGGACGCGGCCTCTGGGCGCTGCCGGGTGGCTTC
GTCAACCAGGACGAACGGCTCGAGACGGCCTGTCTTCGCGAACTGCGCGAGGAAACCGGACTCAAGTTGCCCGAGCCGGT
GCTGCGTGGGTCGCTGAAGGACCGGCAGGTGTTCGACCACCCGCAGCGATCGCTGCGCGGCCGCACCATCACCCACGCGT
TCCTGTTCAGCTTCCCGGTTGGCGAGCTGCCGCGCGTCAAGGGTGGCGATGACGCCGACAAGGCGCGCTGGGTGCCGCTC
AACGATTTCGCCCGCATGAGAAGCGTCATGTTCGAAGACCATTTCGACATCGCCTACCACTTTCTCGGCAAGCTGTAA

Upstream 100 bases:

>100_bases
TATCCCCCTTTTTTCCGTTTGACGCACCGGTGGCGCCGGCATACCATTCAGTCACGGTTACGGGACAGACCCAATTCCGC
CAATCTCTTGAGGGAGCCTC

Downstream 100 bases:

>100_bases
CGCACCCTTCCAGCACGCTTCAGTACCAGCTTTATCCGCCGGGACAGACCTGGCGGCCATCCAACGGCATAGAGGAGCTC
TAGCCATGCAAAACGACCTG

Product: bifunctional nicotinamide mononucleotide adenylyltransferase/ADP-ribose pyrophosphatase

Products: NA

Alternate protein names: Nicotinamide-nucleotide adenylyltransferase; NAD(+) diphosphorylase; NAD(+) pyrophosphorylase; NMN adenylyltransferase; ADP compounds hydrolase [H]

Number of amino acids: Translated: 345; Mature: 344

Protein sequence:

>345_residues
MSTNTKRFDALVFIGRFQPMHRGHVDVLRRALSQADTVCILIGSTDKPRTIKDPFSFDERRQMIESVLDESSRARVRIGA
VQDSTYNDSDWVRWVQDAVAGLLGDTAGRRIGIIGHEKDGSSYYLRMFPQWELVEADSTEDISATEIREQFLAERSNSFV
SWAVPAPVFQWMELFRDRPEFAQLKAEAEFIAGYRKAWSAAPYPVTFVTVDAVVVHSGHLLLVRRRSEPGRGLWALPGGF
VNQDERLETACLRELREETGLKLPEPVLRGSLKDRQVFDHPQRSLRGRTITHAFLFSFPVGELPRVKGGDDADKARWVPL
NDFARMRSVMFEDHFDIAYHFLGKL

Sequences:

>Translated_345_residues
MSTNTKRFDALVFIGRFQPMHRGHVDVLRRALSQADTVCILIGSTDKPRTIKDPFSFDERRQMIESVLDESSRARVRIGA
VQDSTYNDSDWVRWVQDAVAGLLGDTAGRRIGIIGHEKDGSSYYLRMFPQWELVEADSTEDISATEIREQFLAERSNSFV
SWAVPAPVFQWMELFRDRPEFAQLKAEAEFIAGYRKAWSAAPYPVTFVTVDAVVVHSGHLLLVRRRSEPGRGLWALPGGF
VNQDERLETACLRELREETGLKLPEPVLRGSLKDRQVFDHPQRSLRGRTITHAFLFSFPVGELPRVKGGDDADKARWVPL
NDFARMRSVMFEDHFDIAYHFLGKL
>Mature_344_residues
STNTKRFDALVFIGRFQPMHRGHVDVLRRALSQADTVCILIGSTDKPRTIKDPFSFDERRQMIESVLDESSRARVRIGAV
QDSTYNDSDWVRWVQDAVAGLLGDTAGRRIGIIGHEKDGSSYYLRMFPQWELVEADSTEDISATEIREQFLAERSNSFVS
WAVPAPVFQWMELFRDRPEFAQLKAEAEFIAGYRKAWSAAPYPVTFVTVDAVVVHSGHLLLVRRRSEPGRGLWALPGGFV
NQDERLETACLRELREETGLKLPEPVLRGSLKDRQVFDHPQRSLRGRTITHAFLFSFPVGELPRVKGGDDADKARWVPLN
DFARMRSVMFEDHFDIAYHFLGKL

Specific function: The Nudix hydrolase domain is active on ADP-ribose, (2')-phospho-ADP-ribose, IDP-ribose and NADPH [H]

COG id: COG1051

COG function: function code F; ADP-ribose pyrophosphatase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 nudix hydrolase domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004821
- InterPro:   IPR004820
- InterPro:   IPR020084
- InterPro:   IPR000086
- InterPro:   IPR015797
- InterPro:   IPR014729 [H]

Pfam domain/function: PF01467 CTP_transf_2; PF00293 NUDIX [H]

EC number: =2.7.7.1 [H]

Molecular weight: Translated: 39414; Mature: 39283

Theoretical pI: Translated: 7.03; Mature: 7.03

Prosite motif: PS00893 NUDIX

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTNTKRFDALVFIGRFQPMHRGHVDVLRRALSQADTVCILIGSTDKPRTIKDPFSFDER
CCCCCCHHEEEEEEECCCCCCCCHHHHHHHHHHCCCEEEEEEECCCCCCCCCCCCCHHHH
RQMIESVLDESSRARVRIGAVQDSTYNDSDWVRWVQDAVAGLLGDTAGRRIGIIGHEKDG
HHHHHHHHCCCCCCEEEEEEEECCCCCCHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCC
SSYYLRMFPQWELVEADSTEDISATEIREQFLAERSNSFVSWAVPAPVFQWMELFRDRPE
CCEEEEECCCEEEEECCCCCCCHHHHHHHHHHHHHCCCEEEECCCHHHHHHHHHHHCCCH
FAQLKAEAEFIAGYRKAWSAAPYPVTFVTVDAVVVHSGHLLLVRRRSEPGRGLWALPGGF
HHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEEHEEECCCEEEEEECCCCCCEEEECCCCC
VNQDERLETACLRELREETGLKLPEPVLRGSLKDRQVFDHPQRSLRGRTITHAFLFSFPV
CCCHHHHHHHHHHHHHHHHCCCCCCHHHCCCCCCCHHHHCHHHHHCCCHHHHHHHHHCCC
GELPRVKGGDDADKARWVPLNDFARMRSVMFEDHFDIAYHFLGKL
CCCCCCCCCCCCCCCEECCHHHHHHHHHHHHHCCHHHHHHHHHCC
>Mature Secondary Structure 
STNTKRFDALVFIGRFQPMHRGHVDVLRRALSQADTVCILIGSTDKPRTIKDPFSFDER
CCCCCHHEEEEEEECCCCCCCCHHHHHHHHHHCCCEEEEEEECCCCCCCCCCCCCHHHH
RQMIESVLDESSRARVRIGAVQDSTYNDSDWVRWVQDAVAGLLGDTAGRRIGIIGHEKDG
HHHHHHHHCCCCCCEEEEEEEECCCCCCHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCC
SSYYLRMFPQWELVEADSTEDISATEIREQFLAERSNSFVSWAVPAPVFQWMELFRDRPE
CCEEEEECCCEEEEECCCCCCCHHHHHHHHHHHHHCCCEEEECCCHHHHHHHHHHHCCCH
FAQLKAEAEFIAGYRKAWSAAPYPVTFVTVDAVVVHSGHLLLVRRRSEPGRGLWALPGGF
HHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEEHEEECCCEEEEEECCCCCCEEEECCCCC
VNQDERLETACLRELREETGLKLPEPVLRGSLKDRQVFDHPQRSLRGRTITHAFLFSFPV
CCCHHHHHHHHHHHHHHHHCCCCCCHHHCCCCCCCHHHHCHHHHHCCCHHHHHHHHHCCC
GELPRVKGGDDADKARWVPLNDFARMRSVMFEDHFDIAYHFLGKL
CCCCCCCCCCCCCCCEECCHHHHHHHHHHHHHCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8590279; 8905231; 10050763 [H]