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The map label for this gene is atoD [H]

Identifier: 94313981

GI number: 94313981

Start: 1749495

End: 1750175

Strand: Direct

Name: atoD [H]

Synonym: Rmet_5059

Alternate gene names: 94313981

Gene position: 1749495-1750175 (Clockwise)

Preceding gene: 94313980

Following gene: 94313982

Centisome position: 67.81

GC content: 67.4

Gene sequence:

>681_bases
ATGATCGACAAGATCGCGCCCTCGCTCGCCGCCGCGGTGGCGGGCATTGGCGACGGCGCCACGGTGCTGGTCAGCGGCTT
CGGCGGCTCGGGCATTCCCGACGAACTGCTCGATGCCTTGCTGGCCCACGGCGCGCGCGACCTCACCATCGTCAACAACA
ACGCCGGCAACGGCGATGCCGGCATTGCCGCGCTGATCCGCGCGGGCCGCGTGCGCAAGGTCATCTGCTCGCACCCGCGT
TCGAACAATGCCGAGGCGTTCATTGATGCGTATCGCGCCGGCAAGGTCGCGCTCGAGTGCGTGCCGCAGGGCACGCTGGT
GGAGCGGATGCGCGCCGCGGGCGCCGGGCTCGGGCCGTTCTTCACACCCACGGCGTATGGCACCGCGCTGGCCGAAGGCA
AGGAAAGCCGCGTTATCGATGGCACCGGCTACGTGCTGGAACAACCGCTGCACGGCGACTTCGCGCTGATCAAGGCGCAC
CGTGCCGATCGCTGGGGCAATCTGACCTACCGCTATGCAGGTCGCAATTTCGGGCCGGTGATGTGCACTGCCGCGCGGCA
CACCATCGTGCAGGTCGACGAGATCGTCCCGCTGGGCGAGATGACGCCGCAACACGTGATGACGCCGGGAATCTTCGTCC
AGACAGTGGTCCTGGCAACATCGGGAGACAGCCATGCATGA

Upstream 100 bases:

>100_bases
AACAGGAGCGCCAGCGCTGGGCGCGGGTCGTCAAGGACACGGGTATTCCGCAGCAGTAACCGCATCACCGTATCCCAGTC
TCATCGGTAAAGGAGTTCTC

Downstream 100 bases:

>100_bases
CACCCTGCCCCGCCTCGGCACGCTGCCGCGACTGAGCCGCGCCCAGATGGCGCGCATCGTCGCCCATGACATTCCCGATG
GCAGCGTCGTCAATCTCGGC

Product: acetyl-CoA:acetoacetyl-CoA transferase subunit alpha

Products: NA

Alternate protein names: Beta-ketoadipate:succinyl-CoA transferase subunit A [H]

Number of amino acids: Translated: 226; Mature: 226

Protein sequence:

>226_residues
MIDKIAPSLAAAVAGIGDGATVLVSGFGGSGIPDELLDALLAHGARDLTIVNNNAGNGDAGIAALIRAGRVRKVICSHPR
SNNAEAFIDAYRAGKVALECVPQGTLVERMRAAGAGLGPFFTPTAYGTALAEGKESRVIDGTGYVLEQPLHGDFALIKAH
RADRWGNLTYRYAGRNFGPVMCTAARHTIVQVDEIVPLGEMTPQHVMTPGIFVQTVVLATSGDSHA

Sequences:

>Translated_226_residues
MIDKIAPSLAAAVAGIGDGATVLVSGFGGSGIPDELLDALLAHGARDLTIVNNNAGNGDAGIAALIRAGRVRKVICSHPR
SNNAEAFIDAYRAGKVALECVPQGTLVERMRAAGAGLGPFFTPTAYGTALAEGKESRVIDGTGYVLEQPLHGDFALIKAH
RADRWGNLTYRYAGRNFGPVMCTAARHTIVQVDEIVPLGEMTPQHVMTPGIFVQTVVLATSGDSHA
>Mature_226_residues
MIDKIAPSLAAAVAGIGDGATVLVSGFGGSGIPDELLDALLAHGARDLTIVNNNAGNGDAGIAALIRAGRVRKVICSHPR
SNNAEAFIDAYRAGKVALECVPQGTLVERMRAAGAGLGPFFTPTAYGTALAEGKESRVIDGTGYVLEQPLHGDFALIKAH
RADRWGNLTYRYAGRNFGPVMCTAARHTIVQVDEIVPLGEMTPQHVMTPGIFVQTVVLATSGDSHA

Specific function: SHORT-CHAIN FATTY ACIDS METABOLISM. [C]

COG id: COG1788

COG function: function code I; Acyl CoA:acetate/3-ketoacid CoA transferase, alpha subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 3-oxoacid CoA-transferase subunit A family [H]

Homologues:

Organism=Homo sapiens, GI4557817, Length=224, Percent_Identity=43.3035714285714, Blast_Score=182, Evalue=2e-46,
Organism=Homo sapiens, GI11545841, Length=223, Percent_Identity=41.2556053811659, Blast_Score=157, Evalue=1e-38,
Organism=Escherichia coli, GI1788551, Length=212, Percent_Identity=45.2830188679245, Blast_Score=190, Evalue=7e-50,
Organism=Caenorhabditis elegans, GI17531517, Length=238, Percent_Identity=42.0168067226891, Blast_Score=178, Evalue=2e-45,
Organism=Drosophila melanogaster, GI21358325, Length=236, Percent_Identity=38.9830508474576, Blast_Score=177, Evalue=4e-45,
Organism=Drosophila melanogaster, GI24655794, Length=236, Percent_Identity=38.9830508474576, Blast_Score=177, Evalue=4e-45,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012792
- InterPro:   IPR004165
- InterPro:   IPR004163 [H]

Pfam domain/function: PF01144 CoA_trans [H]

EC number: =2.8.3.6 [H]

Molecular weight: Translated: 23528; Mature: 23528

Theoretical pI: Translated: 6.88; Mature: 6.88

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIDKIAPSLAAAVAGIGDGATVLVSGFGGSGIPDELLDALLAHGARDLTIVNNNAGNGDA
CCCHHHHHHHHHHHCCCCCCEEEEECCCCCCCCHHHHHHHHHCCCCEEEEEECCCCCCHH
GIAALIRAGRVRKVICSHPRSNNAEAFIDAYRAGKVALECVPQGTLVERMRAAGAGLGPF
HHHHHHHHCHHHHHHHCCCCCCCHHHHHHHHHCCCEEEEECCCCHHHHHHHHCCCCCCCC
FTPTAYGTALAEGKESRVIDGTGYVLEQPLHGDFALIKAHRADRWGNLTYRYAGRNFGPV
CCCHHHHHHHHCCCCCEEECCCCCEEECCCCCCEEEEEECCCCCCCCEEEEECCCCCCCE
MCTAARHTIVQVDEIVPLGEMTPQHVMTPGIFVQTVVLATSGDSHA
EEECHHHHEEEHHHCCCCCCCCHHHHCCCCHHEEEEEEEECCCCCC
>Mature Secondary Structure
MIDKIAPSLAAAVAGIGDGATVLVSGFGGSGIPDELLDALLAHGARDLTIVNNNAGNGDA
CCCHHHHHHHHHHHCCCCCCEEEEECCCCCCCCHHHHHHHHHCCCCEEEEEECCCCCCHH
GIAALIRAGRVRKVICSHPRSNNAEAFIDAYRAGKVALECVPQGTLVERMRAAGAGLGPF
HHHHHHHHCHHHHHHHCCCCCCCHHHHHHHHHCCCEEEEECCCCHHHHHHHHCCCCCCCC
FTPTAYGTALAEGKESRVIDGTGYVLEQPLHGDFALIKAHRADRWGNLTYRYAGRNFGPV
CCCHHHHHHHHCCCCCEEECCCCCEEECCCCCCEEEEEECCCCCCCCEEEEECCCCCCCE
MCTAARHTIVQVDEIVPLGEMTPQHVMTPGIFVQTVVLATSGDSHA
EEECHHHHEEEHHHCCCCCCCCHHHHCCCCHHEEEEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1624453; 6780551 [H]