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The map label for this gene is paaJ [C]

Identifier: 94313947

GI number: 94313947

Start: 1711192

End: 1712379

Strand: Direct

Name: paaJ [C]

Synonym: Rmet_5025

Alternate gene names: 94313947

Gene position: 1711192-1712379 (Clockwise)

Preceding gene: 94313946

Following gene: 94313948

Centisome position: 66.32

GC content: 65.91

Gene sequence:

>1188_bases
ATGACTCGCAAGGTCTTTGTTGCCGGCGCCGGCATGATCCCGTTCAAGAAGCCGGGCACCAGCGACACCTATGACGTGAT
GGGCGCCACCGCCACGCGCCAGGCGCTGGCCGATGCCGGCGTCGACTACAACCTCGTGCAGCAGGCCTACGTCGGCTACG
TGTACGGCGATTCCACATGCGGCCAGAAGGCGCTTTACGATGTCGGCATGAGCGGCATTCCGGTGATCAACGTCAACAAC
AATTGCGCCACGGGTTCGTCGGCACTGTTCCTGGCCCGCCAGGCCGTGGCAAGCGGCGCCGTGGAATGCGCGCTGGCGCT
CGGCTTCGAGTTCATGGGCCCGGGCGCGCTGAAGTCGGTCTGGACCGACCGACCGAGCGCGTTGGAACGCGCGCTCAACC
TGACCGACAAGCTGGTCGGCAAGACCGAAGGCATGAGCAACGCCATCCGCCAGTTCGCCGGCGCCGGCCAGACGCACATG
CGCAAGCACGGTACCAAGCTGGAAACGTTCGCGAAGATCCGCGCCAAGGCCAGCCGCCACGCCGCGAACAACCCGCTGGC
GGTATTCCGCACCGTGGTCAGCACCGAGGACGTGATGAACGCGCCGATGCTGTGGGATGGCGTGCTGACCCGCCTGATGG
CCTGCCCTCCGACCTGTGGCGCGGCCGCTGCCATCGTCGTATCGGAAGCCTTCGCCCGCAAGCATGGGCTGCGCACTGAC
GTGCTGATCGCCGCCCAATCGCTGACGACCGATCGCGCCAGCAGCTTCGAGAGCGACATGATCCGTCTGGTGGGCTTTGA
CATGACGCGTGAAGGTGCGCGCCAGGTCTACGAGCAAGCCAGCATCGGCCCGCAGGACGTCGACGTGATCGAGCTGCATG
ACTGCTTTGCGCAGAACGAACTGCTGACCTACGAAGGCCTCGGCCTGTGCGACGAAGGCTGCGCCGAGAAGCTGGTCAAT
GACGGCGACAACACCTACGGCGGCAAGTGGGTGGTCAACCCGTCCGGTGGCCTGCTCTCCAAGGGTCATCCACTCGGCGC
CACGGGTCTGGCGCAATGCTACGAGATGGTCCAGCAGCTGCGCGGCAACGCCGATCAGCGCCAGGTGGCCGGCGCGCGTA
ACGCGCTCACGCACAACCTTGGCCTGGGCGGCGCCTGCGTGGTGACGCTCTACCAAAAGCACGACTGA

Upstream 100 bases:

>100_bases
GGCGGCACCAGCGAAGTGATGCGCGACCTCATCTCCCGCAAGCTCTGAACCCCTATCCCCAAGACAACCCTACAGCCATA
CACCTGACAGGAGACTCTCC

Downstream 100 bases:

>100_bases
AGGAGCCCCCAATGATCGACAAGAAGCATATCGGCAAGGTCATCGCGGATTTCCGCACGTCGGCGCCCGCGAGCCAGTTG
CGCTTCTTCGCCAAGGCCAC

Product: lipid-transfer protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 395; Mature: 394

Protein sequence:

>395_residues
MTRKVFVAGAGMIPFKKPGTSDTYDVMGATATRQALADAGVDYNLVQQAYVGYVYGDSTCGQKALYDVGMSGIPVINVNN
NCATGSSALFLARQAVASGAVECALALGFEFMGPGALKSVWTDRPSALERALNLTDKLVGKTEGMSNAIRQFAGAGQTHM
RKHGTKLETFAKIRAKASRHAANNPLAVFRTVVSTEDVMNAPMLWDGVLTRLMACPPTCGAAAAIVVSEAFARKHGLRTD
VLIAAQSLTTDRASSFESDMIRLVGFDMTREGARQVYEQASIGPQDVDVIELHDCFAQNELLTYEGLGLCDEGCAEKLVN
DGDNTYGGKWVVNPSGGLLSKGHPLGATGLAQCYEMVQQLRGNADQRQVAGARNALTHNLGLGGACVVTLYQKHD

Sequences:

>Translated_395_residues
MTRKVFVAGAGMIPFKKPGTSDTYDVMGATATRQALADAGVDYNLVQQAYVGYVYGDSTCGQKALYDVGMSGIPVINVNN
NCATGSSALFLARQAVASGAVECALALGFEFMGPGALKSVWTDRPSALERALNLTDKLVGKTEGMSNAIRQFAGAGQTHM
RKHGTKLETFAKIRAKASRHAANNPLAVFRTVVSTEDVMNAPMLWDGVLTRLMACPPTCGAAAAIVVSEAFARKHGLRTD
VLIAAQSLTTDRASSFESDMIRLVGFDMTREGARQVYEQASIGPQDVDVIELHDCFAQNELLTYEGLGLCDEGCAEKLVN
DGDNTYGGKWVVNPSGGLLSKGHPLGATGLAQCYEMVQQLRGNADQRQVAGARNALTHNLGLGGACVVTLYQKHD
>Mature_394_residues
TRKVFVAGAGMIPFKKPGTSDTYDVMGATATRQALADAGVDYNLVQQAYVGYVYGDSTCGQKALYDVGMSGIPVINVNNN
CATGSSALFLARQAVASGAVECALALGFEFMGPGALKSVWTDRPSALERALNLTDKLVGKTEGMSNAIRQFAGAGQTHMR
KHGTKLETFAKIRAKASRHAANNPLAVFRTVVSTEDVMNAPMLWDGVLTRLMACPPTCGAAAAIVVSEAFARKHGLRTDV
LIAAQSLTTDRASSFESDMIRLVGFDMTREGARQVYEQASIGPQDVDVIELHDCFAQNELLTYEGLGLCDEGCAEKLVND
GDNTYGGKWVVNPSGGLLSKGHPLGATGLAQCYEMVQQLRGNADQRQVAGARNALTHNLGLGGACVVTLYQKHD

Specific function: Thiolytic Cleavage Of Beta-Ketoadipyl-CoA To Succinate And Acetyl-CoA (By Similarity). [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI19923233, Length=398, Percent_Identity=55.5276381909548, Blast_Score=411, Evalue=1e-115,
Organism=Homo sapiens, GI302344760, Length=396, Percent_Identity=52.7777777777778, Blast_Score=377, Evalue=1e-104,
Organism=Homo sapiens, GI302344767, Length=328, Percent_Identity=56.4024390243902, Blast_Score=345, Evalue=4e-95,
Organism=Homo sapiens, GI302344762, Length=397, Percent_Identity=47.8589420654912, Blast_Score=324, Evalue=7e-89,
Organism=Homo sapiens, GI55956775, Length=358, Percent_Identity=45.2513966480447, Blast_Score=268, Evalue=6e-72,
Organism=Caenorhabditis elegans, GI17537653, Length=398, Percent_Identity=45.2261306532663, Blast_Score=325, Evalue=2e-89,
Organism=Drosophila melanogaster, GI24585051, Length=393, Percent_Identity=52.9262086513995, Blast_Score=413, Evalue=1e-115,
Organism=Drosophila melanogaster, GI19921506, Length=397, Percent_Identity=52.6448362720403, Blast_Score=412, Evalue=1e-115,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002155
- InterPro:   IPR016039
- InterPro:   IPR016038
- InterPro:   IPR020617
- InterPro:   IPR020616 [H]

Pfam domain/function: PF02803 Thiolase_C; PF00108 Thiolase_N [H]

EC number: 2.3.1.- [C]

Molecular weight: Translated: 41937; Mature: 41806

Theoretical pI: Translated: 6.91; Mature: 6.91

Prosite motif: PS00098 THIOLASE_1 ; PS00737 THIOLASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTRKVFVAGAGMIPFKKPGTSDTYDVMGATATRQALADAGVDYNLVQQAYVGYVYGDSTC
CCCEEEEECCCCCCCCCCCCCCCHHHHCCHHHHHHHHHCCCCHHHHHHHHHEEEECCCCC
GQKALYDVGMSGIPVINVNNNCATGSSALFLARQAVASGAVECALALGFEFMGPGALKSV
CHHHHHHCCCCCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCHHHCCCHHHHHH
WTDRPSALERALNLTDKLVGKTEGMSNAIRQFAGAGQTHMRKHGTKLETFAKIRAKASRH
HCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCHHHHHHCCCHHHHHHHHHHHHHHH
AANNPLAVFRTVVSTEDVMNAPMLWDGVLTRLMACPPTCGAAAAIVVSEAFARKHGLRTD
CCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCHH
VLIAAQSLTTDRASSFESDMIRLVGFDMTREGARQVYEQASIGPQDVDVIELHDCFAQNE
HEEEHHHHCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCCEEEHHHHHCCCC
LLTYEGLGLCDEGCAEKLVNDGDNTYGGKWVVNPSGGLLSKGHPLGATGLAQCYEMVQQL
EEEECCCCCCCHHHHHHHHCCCCCCCCCEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHH
RGNADQRQVAGARNALTHNLGLGGACVVTLYQKHD
HCCCHHHHHHHHHHHHHHCCCCCCEEEEEEEECCC
>Mature Secondary Structure 
TRKVFVAGAGMIPFKKPGTSDTYDVMGATATRQALADAGVDYNLVQQAYVGYVYGDSTC
CCEEEEECCCCCCCCCCCCCCCHHHHCCHHHHHHHHHCCCCHHHHHHHHHEEEECCCCC
GQKALYDVGMSGIPVINVNNNCATGSSALFLARQAVASGAVECALALGFEFMGPGALKSV
CHHHHHHCCCCCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCHHHCCCHHHHHH
WTDRPSALERALNLTDKLVGKTEGMSNAIRQFAGAGQTHMRKHGTKLETFAKIRAKASRH
HCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCHHHHHHCCCHHHHHHHHHHHHHHH
AANNPLAVFRTVVSTEDVMNAPMLWDGVLTRLMACPPTCGAAAAIVVSEAFARKHGLRTD
CCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCHH
VLIAAQSLTTDRASSFESDMIRLVGFDMTREGARQVYEQASIGPQDVDVIELHDCFAQNE
HEEEHHHHCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCCEEEHHHHHCCCC
LLTYEGLGLCDEGCAEKLVNDGDNTYGGKWVVNPSGGLLSKGHPLGATGLAQCYEMVQQL
EEEECCCCCCCHHHHHHHHCCCCCCCCCEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHH
RGNADQRQVAGARNALTHNLGLGGACVVTLYQKHD
HCCCHHHHHHHHHHHHHHCCCCCCEEEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9371463 [H]