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The map label for this gene is mmgC [H]

Identifier: 94313946

GI number: 94313946

Start: 1710000

End: 1711139

Strand: Direct

Name: mmgC [H]

Synonym: Rmet_5024

Alternate gene names: 94313946

Gene position: 1710000-1711139 (Clockwise)

Preceding gene: 94313945

Following gene: 94313947

Centisome position: 66.28

GC content: 63.77

Gene sequence:

>1140_bases
ATGCAAGTTCAACGTAACGTTTACCGCGAAGATCACGAGATGTTCCGCGAAACCGCCCGCCGCTTCCTGGAGCGCGAGTG
CCTGCCCAAGCAGGGGGCATGGGACAAGGCCGGCAAGGTGGATCGCGAAACCTGGCTCAAGGCCGGTCGCGAAGGTCTGC
TGTGCGTGACGCTGCCCACAGAGTACGGTGGTGGTGGCGGTGACTTCGGCCACTCGGCCGTGTTCAACGAAGAACTGGCG
CGCGTCGGTGTCAGCGGCCTGGGCTTCGGCGTGCATTCGGACATCATCGCCCCGTACATCGCACGCATCGCCAACGAAGA
GCAGAAGCAACGCTGGCTGCCGAAGGTGTGTTCGGGCGAGGCCATTCTCGCCATCGGCATGACCGAACCGGGCACCGGCA
GCGACCTGAAGGCCGTACGCACCACCGCCATTCGCGACGGCGACGAGTACGTGATCAACGGCAGCAAGACCTTCATCTCG
AACGGCCTGAACTGCGACCTGATCATCATGGTCTGCAAGACCGATCCGGCGGCCGGTTCGCGCGGTGTGAGCCTGATCAT
GGTGGAAGCCGACCGAGAGGGTTTCCGCCGTGGGCGCAAGCTGGAGAAAGTCGGCCAGCACGCCCAGGACACGGCCGAGC
TGTTCTTCGACAACGTGCGGGTGCCGGTGTCGAACCTGCTGGGAGAGGAAGGCAAGGGCTTCGCCTACCTGATGGGCGAA
CTGCCGCAGGAGCGCCTGTCGATCGCCGTCAGCGCTGCCGCCAAGCTCGAGGCGTGCCTCGATCACACGATCGCCTACGT
GAAGGAGCGCAAGGCCTTCAACCAGACCGTCTGGGATTTCCAGAACACCAAGTTCAAGCTCGCAGACATCAAGGCACAGG
CCGTTGCCGTGCGCGTGATGGTGGACTACTACCTCAGCGAACATATCCGCCGTCGCCTCTCCCTTGAAGAAGCCGCCATC
GCGAAGCTCTACGCCACCGAGGCGCTGGGCAAGGCGCTCGACGAAATGGTGCAGTTGCACGGCGGCTACGGCTACATGCT
CGAGTACCCGGTGGCGCGCGCGTTCGCCGATTCGCGTGTCACCCGCATCTACGGCGGCACCAGCGAAGTGATGCGCGACC
TCATCTCCCGCAAGCTCTGA

Upstream 100 bases:

>100_bases
GCCCATCTGGTCGAAGCCCTGTTTCATCCCGAACCCGAAAGCCACATTGCCTGCGCGCGATAAGCCCGCCCGCACGACAC
CAACTCAAGAGGAGACTGTC

Downstream 100 bases:

>100_bases
ACCCCTATCCCCAAGACAACCCTACAGCCATACACCTGACAGGAGACTCTCCATGACTCGCAAGGTCTTTGTTGCCGGCG
CCGGCATGATCCCGTTCAAG

Product: putative acyl-CoA dehydrogenase oxidoreductase protein

Products: 2,3-dehydroacyl-CoA; reduced acceptor

Alternate protein names: NA

Number of amino acids: Translated: 379; Mature: 379

Protein sequence:

>379_residues
MQVQRNVYREDHEMFRETARRFLERECLPKQGAWDKAGKVDRETWLKAGREGLLCVTLPTEYGGGGGDFGHSAVFNEELA
RVGVSGLGFGVHSDIIAPYIARIANEEQKQRWLPKVCSGEAILAIGMTEPGTGSDLKAVRTTAIRDGDEYVINGSKTFIS
NGLNCDLIIMVCKTDPAAGSRGVSLIMVEADREGFRRGRKLEKVGQHAQDTAELFFDNVRVPVSNLLGEEGKGFAYLMGE
LPQERLSIAVSAAAKLEACLDHTIAYVKERKAFNQTVWDFQNTKFKLADIKAQAVAVRVMVDYYLSEHIRRRLSLEEAAI
AKLYATEALGKALDEMVQLHGGYGYMLEYPVARAFADSRVTRIYGGTSEVMRDLISRKL

Sequences:

>Translated_379_residues
MQVQRNVYREDHEMFRETARRFLERECLPKQGAWDKAGKVDRETWLKAGREGLLCVTLPTEYGGGGGDFGHSAVFNEELA
RVGVSGLGFGVHSDIIAPYIARIANEEQKQRWLPKVCSGEAILAIGMTEPGTGSDLKAVRTTAIRDGDEYVINGSKTFIS
NGLNCDLIIMVCKTDPAAGSRGVSLIMVEADREGFRRGRKLEKVGQHAQDTAELFFDNVRVPVSNLLGEEGKGFAYLMGE
LPQERLSIAVSAAAKLEACLDHTIAYVKERKAFNQTVWDFQNTKFKLADIKAQAVAVRVMVDYYLSEHIRRRLSLEEAAI
AKLYATEALGKALDEMVQLHGGYGYMLEYPVARAFADSRVTRIYGGTSEVMRDLISRKL
>Mature_379_residues
MQVQRNVYREDHEMFRETARRFLERECLPKQGAWDKAGKVDRETWLKAGREGLLCVTLPTEYGGGGGDFGHSAVFNEELA
RVGVSGLGFGVHSDIIAPYIARIANEEQKQRWLPKVCSGEAILAIGMTEPGTGSDLKAVRTTAIRDGDEYVINGSKTFIS
NGLNCDLIIMVCKTDPAAGSRGVSLIMVEADREGFRRGRKLEKVGQHAQDTAELFFDNVRVPVSNLLGEEGKGFAYLMGE
LPQERLSIAVSAAAKLEACLDHTIAYVKERKAFNQTVWDFQNTKFKLADIKAQAVAVRVMVDYYLSEHIRRRLSLEEAAI
AKLYATEALGKALDEMVQLHGGYGYMLEYPVARAFADSRVTRIYGGTSEVMRDLISRKL

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4501857, Length=377, Percent_Identity=46.9496021220159, Blast_Score=360, Evalue=2e-99,
Organism=Homo sapiens, GI226958412, Length=377, Percent_Identity=35.5437665782493, Blast_Score=242, Evalue=4e-64,
Organism=Homo sapiens, GI226958414, Length=339, Percent_Identity=36.5781710914454, Blast_Score=228, Evalue=6e-60,
Organism=Homo sapiens, GI4501859, Length=379, Percent_Identity=31.1345646437995, Blast_Score=217, Evalue=1e-56,
Organism=Homo sapiens, GI4557233, Length=371, Percent_Identity=33.9622641509434, Blast_Score=215, Evalue=4e-56,
Organism=Homo sapiens, GI7656849, Length=371, Percent_Identity=33.9622641509434, Blast_Score=212, Evalue=4e-55,
Organism=Homo sapiens, GI4557231, Length=375, Percent_Identity=30.9333333333333, Blast_Score=191, Evalue=1e-48,
Organism=Homo sapiens, GI187960098, Length=375, Percent_Identity=30.9333333333333, Blast_Score=191, Evalue=1e-48,
Organism=Homo sapiens, GI76496475, Length=400, Percent_Identity=32, Blast_Score=179, Evalue=3e-45,
Organism=Homo sapiens, GI4557235, Length=400, Percent_Identity=32, Blast_Score=179, Evalue=4e-45,
Organism=Homo sapiens, GI21361497, Length=353, Percent_Identity=32.2946175637394, Blast_Score=175, Evalue=7e-44,
Organism=Homo sapiens, GI38505218, Length=361, Percent_Identity=27.1468144044321, Blast_Score=100, Evalue=2e-21,
Organism=Homo sapiens, GI48976061, Length=356, Percent_Identity=28.3707865168539, Blast_Score=100, Evalue=2e-21,
Organism=Homo sapiens, GI211971008, Length=356, Percent_Identity=28.3707865168539, Blast_Score=100, Evalue=2e-21,
Organism=Homo sapiens, GI4503943, Length=379, Percent_Identity=26.3852242744063, Blast_Score=97, Evalue=2e-20,
Organism=Homo sapiens, GI7669494, Length=364, Percent_Identity=26.6483516483516, Blast_Score=92, Evalue=8e-19,
Organism=Escherichia coli, GI87081958, Length=354, Percent_Identity=29.0960451977401, Blast_Score=139, Evalue=4e-34,
Organism=Escherichia coli, GI1786223, Length=319, Percent_Identity=24.1379310344828, Blast_Score=106, Evalue=3e-24,
Organism=Caenorhabditis elegans, GI17538396, Length=392, Percent_Identity=34.1836734693878, Blast_Score=230, Evalue=8e-61,
Organism=Caenorhabditis elegans, GI17508101, Length=362, Percent_Identity=34.2541436464088, Blast_Score=221, Evalue=4e-58,
Organism=Caenorhabditis elegans, GI17570075, Length=374, Percent_Identity=33.4224598930481, Blast_Score=215, Evalue=4e-56,
Organism=Caenorhabditis elegans, GI17533517, Length=373, Percent_Identity=33.7801608579088, Blast_Score=211, Evalue=5e-55,
Organism=Caenorhabditis elegans, GI17551932, Length=383, Percent_Identity=32.8981723237598, Blast_Score=206, Evalue=2e-53,
Organism=Caenorhabditis elegans, GI17506239, Length=376, Percent_Identity=31.1170212765957, Blast_Score=204, Evalue=7e-53,
Organism=Caenorhabditis elegans, GI17569725, Length=377, Percent_Identity=32.8912466843501, Blast_Score=201, Evalue=4e-52,
Organism=Caenorhabditis elegans, GI17534899, Length=367, Percent_Identity=32.6975476839237, Blast_Score=196, Evalue=1e-50,
Organism=Caenorhabditis elegans, GI17505929, Length=375, Percent_Identity=30.6666666666667, Blast_Score=191, Evalue=8e-49,
Organism=Caenorhabditis elegans, GI71990804, Length=277, Percent_Identity=36.4620938628159, Blast_Score=188, Evalue=4e-48,
Organism=Caenorhabditis elegans, GI71985184, Length=359, Percent_Identity=32.8690807799443, Blast_Score=174, Evalue=6e-44,
Organism=Caenorhabditis elegans, GI71982178, Length=273, Percent_Identity=30.7692307692308, Blast_Score=154, Evalue=8e-38,
Organism=Caenorhabditis elegans, GI32563615, Length=228, Percent_Identity=35.0877192982456, Blast_Score=153, Evalue=1e-37,
Organism=Caenorhabditis elegans, GI71985192, Length=306, Percent_Identity=32.3529411764706, Blast_Score=138, Evalue=4e-33,
Organism=Caenorhabditis elegans, GI17562446, Length=289, Percent_Identity=29.4117647058824, Blast_Score=105, Evalue=6e-23,
Organism=Caenorhabditis elegans, GI17531909, Length=239, Percent_Identity=28.4518828451883, Blast_Score=102, Evalue=4e-22,
Organism=Caenorhabditis elegans, GI17534353, Length=379, Percent_Identity=26.1213720316623, Blast_Score=97, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI86563383, Length=272, Percent_Identity=26.1029411764706, Blast_Score=65, Evalue=5e-11,
Organism=Caenorhabditis elegans, GI86563381, Length=272, Percent_Identity=26.1029411764706, Blast_Score=65, Evalue=6e-11,
Organism=Drosophila melanogaster, GI21355753, Length=375, Percent_Identity=34.4, Blast_Score=220, Evalue=2e-57,
Organism=Drosophila melanogaster, GI24666513, Length=370, Percent_Identity=31.0810810810811, Blast_Score=198, Evalue=4e-51,
Organism=Drosophila melanogaster, GI24660351, Length=375, Percent_Identity=33.3333333333333, Blast_Score=196, Evalue=2e-50,
Organism=Drosophila melanogaster, GI21356377, Length=368, Percent_Identity=29.8913043478261, Blast_Score=188, Evalue=5e-48,
Organism=Drosophila melanogaster, GI24646207, Length=376, Percent_Identity=32.7127659574468, Blast_Score=180, Evalue=1e-45,
Organism=Drosophila melanogaster, GI281363737, Length=356, Percent_Identity=31.4606741573034, Blast_Score=179, Evalue=3e-45,
Organism=Drosophila melanogaster, GI19920834, Length=376, Percent_Identity=26.5957446808511, Blast_Score=99, Evalue=6e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: 1.3.99.3

Molecular weight: Translated: 42097; Mature: 42097

Theoretical pI: Translated: 7.15; Mature: 7.15

Prosite motif: PS00073 ACYL_COA_DH_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQVQRNVYREDHEMFRETARRFLERECLPKQGAWDKAGKVDRETWLKAGREGLLCVTLPT
CCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHCCCCCEEEEEECC
EYGGGGGDFGHSAVFNEELARVGVSGLGFGVHSDIIAPYIARIANEEQKQRWLPKVCSGE
CCCCCCCCCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHCHHHCCCC
AILAIGMTEPGTGSDLKAVRTTAIRDGDEYVINGSKTFISNGLNCDLIIMVCKTDPAAGS
EEEEEECCCCCCCCCHHHHHHHHCCCCCCEEECCCHHHHCCCCCEEEEEEEEECCCCCCC
RGVSLIMVEADREGFRRGRKLEKVGQHAQDTAELFFDNVRVPVSNLLGEEGKGFAYLMGE
CCEEEEEEECCHHHHHCCHHHHHHCCHHHHHHHHHHHCCCCCHHHHCCCCCCCEEEHHHH
LPQERLSIAVSAAAKLEACLDHTIAYVKERKAFNQTVWDFQNTKFKLADIKAQAVAVRVM
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEHHHHHHHHHHH
VDYYLSEHIRRRLSLEEAAIAKLYATEALGKALDEMVQLHGGYGYMLEYPVARAFADSRV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHCCH
TRIYGGTSEVMRDLISRKL
HEEECCHHHHHHHHHHCCC
>Mature Secondary Structure
MQVQRNVYREDHEMFRETARRFLERECLPKQGAWDKAGKVDRETWLKAGREGLLCVTLPT
CCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHCCCCCEEEEEECC
EYGGGGGDFGHSAVFNEELARVGVSGLGFGVHSDIIAPYIARIANEEQKQRWLPKVCSGE
CCCCCCCCCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHCHHHCCCC
AILAIGMTEPGTGSDLKAVRTTAIRDGDEYVINGSKTFISNGLNCDLIIMVCKTDPAAGS
EEEEEECCCCCCCCCHHHHHHHHCCCCCCEEECCCHHHHCCCCCEEEEEEEEECCCCCCC
RGVSLIMVEADREGFRRGRKLEKVGQHAQDTAELFFDNVRVPVSNLLGEEGKGFAYLMGE
CCEEEEEEECCHHHHHCCHHHHHHCCHHHHHHHHHHHCCCCCHHHHCCCCCCCEEEHHHH
LPQERLSIAVSAAAKLEACLDHTIAYVKERKAFNQTVWDFQNTKFKLADIKAQAVAVRVM
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEHHHHHHHHHHH
VDYYLSEHIRRRLSLEEAAIAKLYATEALGKALDEMVQLHGGYGYMLEYPVARAFADSRV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHCCH
TRIYGGTSEVMRDLISRKL
HEEECCHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: acyl-CoA; acceptor

Specific reaction: acyl-CoA + acceptor = 2,3-dehydroacyl-CoA + reduced acceptor

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8759838; 8969508; 9384377 [H]