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The map label for this gene is pknK [H]

Identifier: 94313944

GI number: 94313944

Start: 1705050

End: 1707893

Strand: Direct

Name: pknK [H]

Synonym: Rmet_5022

Alternate gene names: 94313944

Gene position: 1705050-1707893 (Clockwise)

Preceding gene: 94313942

Following gene: 94313945

Centisome position: 66.09

GC content: 67.41

Gene sequence:

>2844_bases
ATGTCCCAGCCTTTTTCCGCGCCGGCTGAATCCGCATCGATCGACGTCTTCGCGGATATCTCCCCCGACGTTTCTCCTGA
CGTTTCTCCCGACGTTTCGCCGCTATCGGCGGCGCGTGCGCATCCGCGCGGCACCGCGCGTGTGGTGGCACGCGAACGGC
TGCTGGCCCAGCTCACCGAGGCTCGCCGCCGCCGCTGCATCGTGATCCAGGGGCCCGCCGGTTTCGGCAAGACGGCCGTG
CTGGTGGCCTGGCGACTAGACCTCCGCGCCCTGGGCTTTGACATGGCCTGGGTGACGCTGGCCGACGACGACAACGAGAT
GACCCACTGGCTCGACCATGTGCTGTCGAGCCTGGCGCAGGTCAGCCCCGCCATCACGCGCGAGGCCGCCCTGCTCGGCG
GCCTGGGCGACCTGGAAAGCGAGGCGATCGAGCGCACCGTGATCGCGCTGGTGGGCGGCATCGCGGCGTGCCCGCGCGAG
ATCGTGCTGGTGATCGACGAACTGCACCGCCTGACCAATCCTCGCGTGCTGGAAGCCATGCAATGGCTGCTGGACTACGC
GCCGCCTAACCTGCATGTGGTGCTGGCCTCGCGCAGCCAGGTGCCGCTCTCGCTGGGACGCCTGCGCGACCAGGACCTCG
TGCTTGAACTCGACCAGCGCGACCTGCGGCTGACCGCCGATGAATCGCGGCGCTTCCTGGCCACGCAGCTGACCGGGATC
GACGCGCGCGATGCGCGGGTACTACACGAGCTGACCGACGGATGGGTAGCCGGCCTGCAACTGTTCGCCACGCACTGGAA
ACGCAAGAAGCAGGACGCCAACAGCCTGTCGTTCGCCAACGATTTCGTGCGCGCCAATGTGCTGAATGCGGGCGCCTTCT
CGGCCTATTTCGAACGCGAGGTGCTGTCACGCCTGGCCCCGGACGAAGCCGAGTTGCTGGTGCACGCGGCCGCCTGCGAG
CGCTTCTGCGCATCGCTTTGTGTCGCCCTGACTGGAGGACGCGCCGATTCGGAACCCGTGGTGTCGGCGCTGCTGGCGCG
GCTCGACAACGAGAACCTGTTTATCGAACCAGTACAGGGGCCCGACCGGGCACCGTGGTACCGGCTGCATCCGCTCCTGC
GCGAAACACTGGCGGAGCGGTTCCGCCAGCGCAGCGAATCGGTGCGGCATCAAGTCCATATGGCGGCCTGGCAGTGGTTC
CGTGATCACCGGTTGCTCGTCGAAGCGGTCAGGCACGCGGTGCTGGCCGGCGAATCCGGTACCGCTGCGGATCTGGTCGA
ACGCTACTCATCGACCCTGATCGGACGTGGCGAGGTGCGCAAGGTGGCGGGCCTGCTGCACCAGCTTCCCAAACCAGAGG
TCCGTGCCCGGCTGGCGTTGCGCCTGCTCACGGTGCAGATGCAACTCTATGCGCACGAAGTTGATGCTGCGCGGGCCGAC
CTCGACGCGCTCGACGGCGAACTGCCAGCCGAAGGGGAGCTGCGCCAGCGCCTCAGGCAACTCCAGACGATGTGGATGGT
GCTGACCGACAACGCCGAGGGCGCGCAGCGGCTACAGCCGTTGCTCGAATCGATGCCGGACGACATCGGCGGCTTGATGG
TTGGCGCGCGCAACAACCTGTTGACGTGGCTCTACATGCATCAGGGCAACTACGAGCGCGCCCGCGCCATCCAGTCGGAA
AACGCGCCATTGATCGTCGAGGGCGCGCCGCTGCTCGGCAGCGCGGCCGGCATGCTCAACGGCCGATGCATGGCCGCCTT
CAGCTACGCGATAGAAGGCAAGATCACGCAGGTGGAGCGCATTTGCCGTGACGTGATACGAGAAAGCGAACAGGCCGGCG
CATTCGGGACTGAGCCCGAGTACTTTGCGGCAGCCATGCTTGGCGAGGTGCTCTACGAGCAGAACCAGATCGAAGCCGCG
CTGGCCATGCTGGAGCCCCGTGTGGACGTGCTGGAGCGGATCTCGATTCCCGATTCGGTATTGCGCGTCTTCATGACGCT
GGCGAACTGCCATGCCGCTCGTGGTCACCATCTGGATGCCTTTGCCTACCTCGAACGGCTGGAAGAACATGCCACGCGAC
GCAGGCTCGATCGTTTGCTTGCGCACAGCCTCGCCGGCCAGGTCCGGTTGCATCGGCGAGCCGGCGACCCTGCCGCGGCG
GATGCCTGCCTGGCGCGGCTCGAGGCCATCGCCGAACGCCACCGCGACGCGGGCCCTGGCACCATGGACGAGATCCTTCT
GGTGGCACGCCGCGCGCGCGTCAAGGGATACCTGGACGACGGTGATCCCGCGAAGGCGGCCGCCGCCGTCGGCCCGCTGA
TCGACCAGTGTCAACGACGCGGATGGCAACGCCATCTCGCGCAGATGCAGTGGATGGCAGCGCTGGCCGATCATCGACTC
GGCAACGATGCGTCCGCGCGCGAGCGCGTGCTGGCTGCATTGCGCGCGGGCCACCGGCTTGGCCTGGTGCGCAGCCTGCT
CGACGTTGACCCGGGCGCGCTCGACGAGATTGCCGCACTGGCGCAACAGCCCGGCGAAGCGCCCGATCCGCTGCTCGCGT
TCTACATCAGCCGCCTGCGCGCGACCGGTGCCACCAACCCGATGACATCAGCCCGCGCTGCGGCACCGGCCACGCTGCGC
ACCCTGGCGGAGCCACTGAGCGAACGCGAAGCCGATGTGGTGGAGTTGCTCGGACAAGCGCTGCCCAACAAGAAGATCGC
CCGCACGCTCGGCCTATCGCCCGAGACCGTGAAGTGGCACCTCCGCAACATCTTCCGCAAGCTTGGCGTGACATCGCGCG
ACGAAGCCGTCGCGCGTGTGCGCGACCTTTCCCGCCCGAGCTGA

Upstream 100 bases:

>100_bases
GCTTTTGCTCCTCCCGCGCCACCGGGGCGGCGAGTAGAATCGCTTGGCATCGGGCCCTTGCCCCTCCTGCGCGCCGCTGC
ATCCGGCGCTGGTCAAACCC

Downstream 100 bases:

>100_bases
CCCGGGCACTCCTTCCCTCGCGAAAGCGACCGCGCCACCTGACATGGGTGGTAGTGGCCGCCCCCTCCCCGGGCGTAACT
TAGCGTCATTCGATCGCACG

Product: ATP-dependent transcriptional regulator, MalT-like, LuxR family

Products: NA

Alternate protein names: Protein kinase K [H]

Number of amino acids: Translated: 947; Mature: 946

Protein sequence:

>947_residues
MSQPFSAPAESASIDVFADISPDVSPDVSPDVSPLSAARAHPRGTARVVARERLLAQLTEARRRRCIVIQGPAGFGKTAV
LVAWRLDLRALGFDMAWVTLADDDNEMTHWLDHVLSSLAQVSPAITREAALLGGLGDLESEAIERTVIALVGGIAACPRE
IVLVIDELHRLTNPRVLEAMQWLLDYAPPNLHVVLASRSQVPLSLGRLRDQDLVLELDQRDLRLTADESRRFLATQLTGI
DARDARVLHELTDGWVAGLQLFATHWKRKKQDANSLSFANDFVRANVLNAGAFSAYFEREVLSRLAPDEAELLVHAAACE
RFCASLCVALTGGRADSEPVVSALLARLDNENLFIEPVQGPDRAPWYRLHPLLRETLAERFRQRSESVRHQVHMAAWQWF
RDHRLLVEAVRHAVLAGESGTAADLVERYSSTLIGRGEVRKVAGLLHQLPKPEVRARLALRLLTVQMQLYAHEVDAARAD
LDALDGELPAEGELRQRLRQLQTMWMVLTDNAEGAQRLQPLLESMPDDIGGLMVGARNNLLTWLYMHQGNYERARAIQSE
NAPLIVEGAPLLGSAAGMLNGRCMAAFSYAIEGKITQVERICRDVIRESEQAGAFGTEPEYFAAAMLGEVLYEQNQIEAA
LAMLEPRVDVLERISIPDSVLRVFMTLANCHAARGHHLDAFAYLERLEEHATRRRLDRLLAHSLAGQVRLHRRAGDPAAA
DACLARLEAIAERHRDAGPGTMDEILLVARRARVKGYLDDGDPAKAAAAVGPLIDQCQRRGWQRHLAQMQWMAALADHRL
GNDASARERVLAALRAGHRLGLVRSLLDVDPGALDEIAALAQQPGEAPDPLLAFYISRLRATGATNPMTSARAAAPATLR
TLAEPLSEREADVVELLGQALPNKKIARTLGLSPETVKWHLRNIFRKLGVTSRDEAVARVRDLSRPS

Sequences:

>Translated_947_residues
MSQPFSAPAESASIDVFADISPDVSPDVSPDVSPLSAARAHPRGTARVVARERLLAQLTEARRRRCIVIQGPAGFGKTAV
LVAWRLDLRALGFDMAWVTLADDDNEMTHWLDHVLSSLAQVSPAITREAALLGGLGDLESEAIERTVIALVGGIAACPRE
IVLVIDELHRLTNPRVLEAMQWLLDYAPPNLHVVLASRSQVPLSLGRLRDQDLVLELDQRDLRLTADESRRFLATQLTGI
DARDARVLHELTDGWVAGLQLFATHWKRKKQDANSLSFANDFVRANVLNAGAFSAYFEREVLSRLAPDEAELLVHAAACE
RFCASLCVALTGGRADSEPVVSALLARLDNENLFIEPVQGPDRAPWYRLHPLLRETLAERFRQRSESVRHQVHMAAWQWF
RDHRLLVEAVRHAVLAGESGTAADLVERYSSTLIGRGEVRKVAGLLHQLPKPEVRARLALRLLTVQMQLYAHEVDAARAD
LDALDGELPAEGELRQRLRQLQTMWMVLTDNAEGAQRLQPLLESMPDDIGGLMVGARNNLLTWLYMHQGNYERARAIQSE
NAPLIVEGAPLLGSAAGMLNGRCMAAFSYAIEGKITQVERICRDVIRESEQAGAFGTEPEYFAAAMLGEVLYEQNQIEAA
LAMLEPRVDVLERISIPDSVLRVFMTLANCHAARGHHLDAFAYLERLEEHATRRRLDRLLAHSLAGQVRLHRRAGDPAAA
DACLARLEAIAERHRDAGPGTMDEILLVARRARVKGYLDDGDPAKAAAAVGPLIDQCQRRGWQRHLAQMQWMAALADHRL
GNDASARERVLAALRAGHRLGLVRSLLDVDPGALDEIAALAQQPGEAPDPLLAFYISRLRATGATNPMTSARAAAPATLR
TLAEPLSEREADVVELLGQALPNKKIARTLGLSPETVKWHLRNIFRKLGVTSRDEAVARVRDLSRPS
>Mature_946_residues
SQPFSAPAESASIDVFADISPDVSPDVSPDVSPLSAARAHPRGTARVVARERLLAQLTEARRRRCIVIQGPAGFGKTAVL
VAWRLDLRALGFDMAWVTLADDDNEMTHWLDHVLSSLAQVSPAITREAALLGGLGDLESEAIERTVIALVGGIAACPREI
VLVIDELHRLTNPRVLEAMQWLLDYAPPNLHVVLASRSQVPLSLGRLRDQDLVLELDQRDLRLTADESRRFLATQLTGID
ARDARVLHELTDGWVAGLQLFATHWKRKKQDANSLSFANDFVRANVLNAGAFSAYFEREVLSRLAPDEAELLVHAAACER
FCASLCVALTGGRADSEPVVSALLARLDNENLFIEPVQGPDRAPWYRLHPLLRETLAERFRQRSESVRHQVHMAAWQWFR
DHRLLVEAVRHAVLAGESGTAADLVERYSSTLIGRGEVRKVAGLLHQLPKPEVRARLALRLLTVQMQLYAHEVDAARADL
DALDGELPAEGELRQRLRQLQTMWMVLTDNAEGAQRLQPLLESMPDDIGGLMVGARNNLLTWLYMHQGNYERARAIQSEN
APLIVEGAPLLGSAAGMLNGRCMAAFSYAIEGKITQVERICRDVIRESEQAGAFGTEPEYFAAAMLGEVLYEQNQIEAAL
AMLEPRVDVLERISIPDSVLRVFMTLANCHAARGHHLDAFAYLERLEEHATRRRLDRLLAHSLAGQVRLHRRAGDPAAAD
ACLARLEAIAERHRDAGPGTMDEILLVARRARVKGYLDDGDPAKAAAAVGPLIDQCQRRGWQRHLAQMQWMAALADHRLG
NDASARERVLAALRAGHRLGLVRSLLDVDPGALDEIAALAQQPGEAPDPLLAFYISRLRATGATNPMTSARAAAPATLRT
LAEPLSEREADVVELLGQALPNKKIARTLGLSPETVKWHLRNIFRKLGVTSRDEAVARVRDLSRPS

Specific function: Modulates the activity of transcription regulator virS via phosphorylation [H]

COG id: COG2909

COG function: function code K; ATP-dependent transcriptional regulator

Gene ontology:

Cell location: Cell membrane. Note=Probably attached to cell membrane through interactions mediated by its C- terminal region (By similarity) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 protein kinase domain [H]

Homologues:

Organism=Escherichia coli, GI2367223, Length=396, Percent_Identity=26.010101010101, Blast_Score=121, Evalue=2e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011009
- InterPro:   IPR000719
- InterPro:   IPR017441
- InterPro:   IPR017442
- InterPro:   IPR016236
- InterPro:   IPR011990 [H]

Pfam domain/function: PF00069 Pkinase [H]

EC number: =2.7.11.1 [H]

Molecular weight: Translated: 104411; Mature: 104280

Theoretical pI: Translated: 6.61; Mature: 6.61

Prosite motif: PS50043 HTH_LUXR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQPFSAPAESASIDVFADISPDVSPDVSPDVSPLSAARAHPRGTARVVARERLLAQLTE
CCCCCCCCCCCCCEEEEECCCCCCCCCCCCCCCHHHHHHCCCCCHHHHHHHHHHHHHHHH
ARRRRCIVIQGPAGFGKTAVLVAWRLDLRALGFDMAWVTLADDDNEMTHWLDHVLSSLAQ
HHCCEEEEEECCCCCCCCHHHHHHHHHHHHHCCCEEEEEEECCCCHHHHHHHHHHHHHHH
VSPAITREAALLGGLGDLESEAIERTVIALVGGIAACPREIVLVIDELHRLTNPRVLEAM
HCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHCCCCHHHHHH
QWLLDYAPPNLHVVLASRSQVPLSLGRLRDQDLVLELDQRDLRLTADESRRFLATQLTGI
HHHHHCCCCCEEEEEECCCCCCHHHHHCCCCCCEEEECCCCCEEEHHHHHHHHHHHHCCC
DARDARVLHELTDGWVAGLQLFATHWKRKKQDANSLSFANDFVRANVLNAGAFSAYFERE
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCHHHHHHHHHH
VLSRLAPDEAELLVHAAACERFCASLCVALTGGRADSEPVVSALLARLDNENLFIEPVQG
HHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCEEEEECCC
PDRAPWYRLHPLLRETLAERFRQRSESVRHQVHMAAWQWFRDHRLLVEAVRHAVLAGESG
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
TAADLVERYSSTLIGRGEVRKVAGLLHQLPKPEVRARLALRLLTVQMQLYAHEVDAARAD
CHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LDALDGELPAEGELRQRLRQLQTMWMVLTDNAEGAQRLQPLLESMPDDIGGLMVGARNNL
HHHHCCCCCCCHHHHHHHHHHHHHHHHEECCCCHHHHHHHHHHHCCHHHCCEEEECCCCE
LTWLYMHQGNYERARAIQSENAPLIVEGAPLLGSAAGMLNGRCMAAFSYAIEGKITQVER
EEEEEEECCCHHHHHHHHCCCCCEEEECCCCHHHHHHHCCCHHHHHHHHHHCCCHHHHHH
ICRDVIRESEQAGAFGTEPEYFAAAMLGEVLYEQNQIEAALAMLEPRVDVLERISIPDSV
HHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCHHH
LRVFMTLANCHAARGHHLDAFAYLERLEEHATRRRLDRLLAHSLAGQVRLHRRAGDPAAA
HHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHH
DACLARLEAIAERHRDAGPGTMDEILLVARRARVKGYLDDGDPAKAAAAVGPLIDQCQRR
HHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHH
GWQRHLAQMQWMAALADHRLGNDASARERVLAALRAGHRLGLVRSLLDVDPGALDEIAAL
HHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHCCCCHHHHHHHH
AQQPGEAPDPLLAFYISRLRATGATNPMTSARAAAPATLRTLAEPLSEREADVVELLGQA
HHCCCCCCCHHHHHHHHHHHHCCCCCCCCHHHHCCHHHHHHHHHHHHHCCHHHHHHHHHH
LPNKKIARTLGLSPETVKWHLRNIFRKLGVTSRDEAVARVRDLSRPS
CCCHHHHHHHCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCC
>Mature Secondary Structure 
SQPFSAPAESASIDVFADISPDVSPDVSPDVSPLSAARAHPRGTARVVARERLLAQLTE
CCCCCCCCCCCCEEEEECCCCCCCCCCCCCCCHHHHHHCCCCCHHHHHHHHHHHHHHHH
ARRRRCIVIQGPAGFGKTAVLVAWRLDLRALGFDMAWVTLADDDNEMTHWLDHVLSSLAQ
HHCCEEEEEECCCCCCCCHHHHHHHHHHHHHCCCEEEEEEECCCCHHHHHHHHHHHHHHH
VSPAITREAALLGGLGDLESEAIERTVIALVGGIAACPREIVLVIDELHRLTNPRVLEAM
HCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHCCCCHHHHHH
QWLLDYAPPNLHVVLASRSQVPLSLGRLRDQDLVLELDQRDLRLTADESRRFLATQLTGI
HHHHHCCCCCEEEEEECCCCCCHHHHHCCCCCCEEEECCCCCEEEHHHHHHHHHHHHCCC
DARDARVLHELTDGWVAGLQLFATHWKRKKQDANSLSFANDFVRANVLNAGAFSAYFERE
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCHHHHHHHHHH
VLSRLAPDEAELLVHAAACERFCASLCVALTGGRADSEPVVSALLARLDNENLFIEPVQG
HHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCEEEEECCC
PDRAPWYRLHPLLRETLAERFRQRSESVRHQVHMAAWQWFRDHRLLVEAVRHAVLAGESG
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
TAADLVERYSSTLIGRGEVRKVAGLLHQLPKPEVRARLALRLLTVQMQLYAHEVDAARAD
CHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LDALDGELPAEGELRQRLRQLQTMWMVLTDNAEGAQRLQPLLESMPDDIGGLMVGARNNL
HHHHCCCCCCCHHHHHHHHHHHHHHHHEECCCCHHHHHHHHHHHCCHHHCCEEEECCCCE
LTWLYMHQGNYERARAIQSENAPLIVEGAPLLGSAAGMLNGRCMAAFSYAIEGKITQVER
EEEEEEECCCHHHHHHHHCCCCCEEEECCCCHHHHHHHCCCHHHHHHHHHHCCCHHHHHH
ICRDVIRESEQAGAFGTEPEYFAAAMLGEVLYEQNQIEAALAMLEPRVDVLERISIPDSV
HHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCHHH
LRVFMTLANCHAARGHHLDAFAYLERLEEHATRRRLDRLLAHSLAGQVRLHRRAGDPAAA
HHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHH
DACLARLEAIAERHRDAGPGTMDEILLVARRARVKGYLDDGDPAKAAAAVGPLIDQCQRR
HHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHH
GWQRHLAQMQWMAALADHRLGNDASARERVLAALRAGHRLGLVRSLLDVDPGALDEIAAL
HHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHCCCCHHHHHHHH
AQQPGEAPDPLLAFYISRLRATGATNPMTSARAAAPATLRTLAEPLSEREADVVELLGQA
HHCCCCCCCHHHHHHHHHHHHCCCCCCCCHHHHCCHHHHHHHHHHHHHCCHHHHHHHHHH
LPNKKIARTLGLSPETVKWHLRNIFRKLGVTSRDEAVARVRDLSRPS
CCCHHHHHHHCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]