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The map label for this gene is cimH [H]

Identifier: 94313920

GI number: 94313920

Start: 1677114

End: 1678460

Strand: Reverse

Name: cimH [H]

Synonym: Rmet_4998

Alternate gene names: 94313920

Gene position: 1678460-1677114 (Counterclockwise)

Preceding gene: 291481552

Following gene: 94313919

Centisome position: 65.05

GC content: 61.1

Gene sequence:

>1347_bases
ATGGAAGCCGAACCGGTCGTTACGCAACCCAACGAAGCACCTCAGAACGCAAGATTCTGGCCTCATGGCTGGTGGCGCCT
GATGGAAATTCGCATCGGCATCTTCCCGCTGCCGGTCTATATCCTGGCCGCCGCACTGCTCGCTGTACTGATCTCCATCC
ACAAGCTTGCCAACGAGATCTCGCTGGTCATTGTCCTGTTTGCATTCTGCGGCTTCACGCTCGCGGAGATCGGCAAGCGC
ATCCCTCTTATCCGCGCCATCGGCGCGGCGGCCATCTTCGCCACCTTCGTGCCATCCGCGCTGGTGTACTACAAGCTCTT
GCCCGAGCAGGTGGTCAAAGTCACAGCGGACTTTACCAAGGCAACGAATTTTCTCTACCTGTTCATCGCCTGCATCATCG
TCGGCAGCATTCTTGGCATGGATCGCCATGTGCTGATCAAGGGCTTCCTGAAGATATTCGTGCCGCTGGCCGCGGGTTCC
ATCGCGGCGGGCGCGGTCGGCACGCTTGTCGGCACCGCACTCGGCCTCGGTACCTCGCACACGTTCTTCTATATCGTCGT
GCCCATCATGGCCGGCGGTGTAGGCGAGGGGGCGATTCCGCTCTCCATCGGCTACAGCGAGATCCTTCACCAGGACCAGG
GCCTTTTGTTCGCGACGGTACTGCCGCCCGTGATGCTTGGCAGTCTTACCGCGATCATCCTGTCCGGCACGCTGAACTAC
CTGGGCAAACGCTACCCCGCCTATACCGGCGAGGGCCGTCTGCAACCCGGCGAGCACGATGAACTGGACGCGAACCAGAA
GGAAATCACTGGGCACGTCGATGTGGACCACATCGCCGCGGCGGGCGTAACGGCGCTGACTCTCTATGTGGTCGGTATCA
TGTGCCATCGCCTCTTCGGTCTGCCGGCGCCGGTGGCCATGCTCTTCATCGCGGTACTGCTCAAGCTGACGCAGGCCGTG
TCACCACCACTGCAGGAGGGTGCATTTGTGGTGTACAAGTTCTTCTCGACGGCGGTCACCTACCCGTTGCTGTTCGCGAT
CGGCGTGTCGTTGACACCTTGGGACAAACTGATCGCCGCATTCAACCTGCCGACGATCATCACCATCGTCGCCACCGTGG
CAACGCTGATGGCCGTTGGCGCCTTGGTGGGCACCTGGATGAAGATGTACCCGATCGACACCGCCATCGTAACTGCCTGC
CACAGCGGCCAGGGAGGAACAGGGGACGTGGCGATTCTTACCGCCGCCAACCGGATGACGCTTATGCCTTTCGCGCAGAT
TGCAACCCGCATTGGCGGCGCCGTGACGGTCACGGTGGTGTTGCTCGTGCTGGCGCGGATGCAGTAA

Upstream 100 bases:

>100_bases
TACCAAGATGGACAGCAAACCGGACGCTGTCGACCCCAACAGGCGGTCTGAACTGCCTGCCTGCGCCGCGCCGGCCCCTC
GCCTTCGGAGAACGTCAGCC

Downstream 100 bases:

>100_bases
GAAGGACGCGACTGTGGTCCCTTTCCGGCCAGGAACCGACACCCGACATGCCTGCCTGGATTGCACACAATTCCAATTCA
AGTGCACCAACTGGACATCC

Product: citrate carrier protein

Products: NA

Alternate protein names: Citrate/malate-proton symporter [H]

Number of amino acids: Translated: 448; Mature: 448

Protein sequence:

>448_residues
MEAEPVVTQPNEAPQNARFWPHGWWRLMEIRIGIFPLPVYILAAALLAVLISIHKLANEISLVIVLFAFCGFTLAEIGKR
IPLIRAIGAAAIFATFVPSALVYYKLLPEQVVKVTADFTKATNFLYLFIACIIVGSILGMDRHVLIKGFLKIFVPLAAGS
IAAGAVGTLVGTALGLGTSHTFFYIVVPIMAGGVGEGAIPLSIGYSEILHQDQGLLFATVLPPVMLGSLTAIILSGTLNY
LGKRYPAYTGEGRLQPGEHDELDANQKEITGHVDVDHIAAAGVTALTLYVVGIMCHRLFGLPAPVAMLFIAVLLKLTQAV
SPPLQEGAFVVYKFFSTAVTYPLLFAIGVSLTPWDKLIAAFNLPTIITIVATVATLMAVGALVGTWMKMYPIDTAIVTAC
HSGQGGTGDVAILTAANRMTLMPFAQIATRIGGAVTVTVVLLVLARMQ

Sequences:

>Translated_448_residues
MEAEPVVTQPNEAPQNARFWPHGWWRLMEIRIGIFPLPVYILAAALLAVLISIHKLANEISLVIVLFAFCGFTLAEIGKR
IPLIRAIGAAAIFATFVPSALVYYKLLPEQVVKVTADFTKATNFLYLFIACIIVGSILGMDRHVLIKGFLKIFVPLAAGS
IAAGAVGTLVGTALGLGTSHTFFYIVVPIMAGGVGEGAIPLSIGYSEILHQDQGLLFATVLPPVMLGSLTAIILSGTLNY
LGKRYPAYTGEGRLQPGEHDELDANQKEITGHVDVDHIAAAGVTALTLYVVGIMCHRLFGLPAPVAMLFIAVLLKLTQAV
SPPLQEGAFVVYKFFSTAVTYPLLFAIGVSLTPWDKLIAAFNLPTIITIVATVATLMAVGALVGTWMKMYPIDTAIVTAC
HSGQGGTGDVAILTAANRMTLMPFAQIATRIGGAVTVTVVLLVLARMQ
>Mature_448_residues
MEAEPVVTQPNEAPQNARFWPHGWWRLMEIRIGIFPLPVYILAAALLAVLISIHKLANEISLVIVLFAFCGFTLAEIGKR
IPLIRAIGAAAIFATFVPSALVYYKLLPEQVVKVTADFTKATNFLYLFIACIIVGSILGMDRHVLIKGFLKIFVPLAAGS
IAAGAVGTLVGTALGLGTSHTFFYIVVPIMAGGVGEGAIPLSIGYSEILHQDQGLLFATVLPPVMLGSLTAIILSGTLNY
LGKRYPAYTGEGRLQPGEHDELDANQKEITGHVDVDHIAAAGVTALTLYVVGIMCHRLFGLPAPVAMLFIAVLLKLTQAV
SPPLQEGAFVVYKFFSTAVTYPLLFAIGVSLTPWDKLIAAFNLPTIITIVATVATLMAVGALVGTWMKMYPIDTAIVTAC
HSGQGGTGDVAILTAANRMTLMPFAQIATRIGGAVTVTVVLLVLARMQ

Specific function: Proton motive force-driven secondary transporter that catalyzes the uptake of both citrate and malate. Appears to be an electroneutral proton-solute symporter; the number of protons transported is equal to the valence of the transported anions. Is strictl

COG id: COG3493

COG function: function code C; Na+/citrate symporter

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sodium:citrate (SCF) symporter family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004679
- InterPro:   IPR018025 [H]

Pfam domain/function: PF03390 2HCT [H]

EC number: NA

Molecular weight: Translated: 47651; Mature: 47651

Theoretical pI: Translated: 8.01; Mature: 8.01

Prosite motif: PS00237 G_PROTEIN_RECEP_F1_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHHCCHHHHHHHHHHHHHCC
>Mature Secondary Structure
MEAEPVVTQPNEAPQNARFWPHGWWRLMEIRIGIFPLPVYILAAALLAVLISIHKLANEI
CCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHH
SLVIVLFAFCGFTLAEIGKRIPLIRAIGAAAIFATFVPSALVYYKLLPEQVVKVTADFTK
HHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ATNFLYLFIACIIVGSILGMDRHVLIKGFLKIFVPLAAGSIAAGAVGTLVGTALGLGTSH
HHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCC
TFFYIVVPIMAGGVGEGAIPLSIGYSEILHQDQGLLFATVLPPVMLGSLTAIILSGTLNY
HHHHHHHHHHCCCCCCCCEEEECCHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
LGKRYPAYTGEGRLQPGEHDELDANQKEITGHVDVDHIAAAGVTALTLYVVGIMCHRLFG
HHCCCCCCCCCCCCCCCCCCCCCCCHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHC
LPAPVAMLFIAVLLKLTQAVSPPLQEGAFVVYKFFSTAVTYPLLFAIGVSLTPWDKLIAA
CCHHHHHHHHHHHHHHHHHCCCCHHCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHH
FNLPTIITIVATVATLMAVGALVGTWMKMYPIDTAIVTACHSGQGGTGDVAILTAANRMT
HCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCCCEEEEEECCCEE
LMPFAQIATRIGGAVTVTVVLLVLARMQ
HHHHHHHHHHHCCHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8969509; 9384377; 11566984 [H]