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The map label for this gene is pyc [H]

Identifier: 94313893

GI number: 94313893

Start: 1645470

End: 1648928

Strand: Reverse

Name: pyc [H]

Synonym: Rmet_4971

Alternate gene names: 94313893

Gene position: 1648928-1645470 (Counterclockwise)

Preceding gene: 94313898

Following gene: 94313892

Centisome position: 63.91

GC content: 66.78

Gene sequence:

>3459_bases
GTGCACACGAGTATTGAGCATAGACGAGTTTCGTGCAGAGGAGTCCTGATATCTGGCTGTCAGGAGCCGTATGCACAAGA
GGCTTCAAACCGCGCTGAATGGTGCAGTCGTCTTCTGAAAATGACAACTGAATTGAAGAAGCTGTTGATCGCCAACCGCG
GAGAGATTGCATTGCGCGTCCAGCGCGCCGCACGCGACCTGGATATTGGCACCGTCGCGGTGTACTCGCAGGACGACGCG
GGCTGCCGCCATCGGATGCTGGCCGACGAAGCGATTGCGCTGGACGGTGCGGGCCCTGCTGCGTACATCGACATCGCGGG
AATCATCGCTGCCGCGAAGGCATCGGGCAGCGATGCCGTACACCCGGGCTACGGCTTTCTGAGTGAGCGGGCCGATTTTG
CGCAGGCGTGCATCGATGCCGGCATCCGGTTCATCGGACCGACGGTCGAGCATCTCGCGCTGTTCGGCGACAAGGGCCGC
GCGCTGCAATTGGCGGCCGAGTGCGACGTGCCGGTCATGCCCGCCACGCATGGCGGCGCGTCCCTGGAGGAGATCGAACG
CTTCTTCGATGCACAGGGCGACGCCGGCATTGTCATCAAGGCGGTTGGCGGTGGCGGCGGGCGCGGCATGCGCGTGGTGC
GCAGACGCGAGGATCTGGCGGAGGCCTATGCGCGCTGCCGGTCCGAGGCCAGTTCCGCGTTTGGCGTGGATGCGCTGTAC
GCCGAGCGGCTGGTCAGCCGGGCACGCCATATCGAAGTGCAGATCGCTGGCGACGGCCAGCACGTTATTGCGCTGGGCGA
GCGGGACTGCACGCTGCAGCGCCGTTTCCAGAAACTGGTGGAGATTGCCCCGAGCCCGGTGCTCAAGCCGGAGCTGCGCG
CGGAGATTATCAAGGCCGCGCTGCGGCTGGCGCGTCGCGTCAACTACCAGAGCCTGGGCACGTTCGAATTTCTGGTCGAG
GAAAGCGAGTCGGGCGAGCAGAAGCGCTTCGTCTTTATCGAAGCCAATCCCCGGCTGCAGGTGGAGCACACCATCACCGA
GCAGGTGACCGGCGTGGATCTCGTGGCGCTGCAGATCGGGCTGGCCTCCGGGCGGACGCTCGTCGAACTTGGGCTCGATC
CGGCTTCGCCGCCGCAACCCCGGGGCTATGCGATCCAGGTGCGCGTCAATGCCGAAATGACCGATGCGCAAGGGCTTGCG
CGTCCGGCATTTGGCCGTCTGGAGCGCTTCGAGCCGCCCGCCGGTCCGGATGTGCGGGTGGACTCCCACGGCTACGCCGG
CTACGAGCCGTCGCCGAACTTCGACACCCTGCTGGCCAAGCTGATCGTAAGCAGCGCCGCACCCGGGTTCGAAGCTGCCG
TGCGCCGGCTGCAGCGCAGTCTCGCGGAATTCCGCATCGTTGGCGTGCCGACCAACCTCAACCTGTTGCGGGCGCTTGCC
CAACGCGAGGACTTCCTGACGCAGGACGTCCACACGCGTCTTTTCGAGTCGATCCTGCCGGCGCTGATGGCGTCGGCGGA
AACCATCGCCGAAGCCGAGCGCGCGCAGGACGCGCGTTTCGGCGGCGCATCCCATGCAACGCCCGTCCACGCGAGCCACG
CGACCCGCGCGCCGGAGGCTGAAGAGGAACTGGAAGAAGGGCTCGTGGCGATCCGCGCGCCGCTGACTGGCCGCGTGGTC
GACATCCCGGTGCAACTGGACGAGATCGTCAAGCCTGGGCAGACGGTGGCCGTGCTAGATGCGATGAAGATGGAGCATGC
GATTGTCGCGCCGTGCGCGGGCCGTGTGGTCGATCTGCGCCCGGAGAAGGGTGCGCTGGTGTCCGAAGGCCACATGCTGA
TCGTGCTCGAGCAGGCAGAGGCCGACGGCGTGGCCGTGGATGCCGCGCGGAATGTCGATCCGAATGCGATCCGTGCGGAT
CTGCAGCGTGTGCTGGACCGGCACGCCTATCTGTATGACGCGGCGCGTCCCGATGCGGTGGCCAAACGCCGTTCGCGCGG
GCAGCGCACGGCGCGGGAGAACATCGCCGACCTGTGCGATGGCGACTCCTTCGTGGAATATGGCGCGCTCGCGCTGGCCG
CGCAGGCATCCCGCCGCAGCAAGGAAGACCTGATCGTCAACACGCCCGCGGATGGCCTGATCACCGGTATCGGCGAGATC
AACCGGGAACTGGTCGCGAAGGAACGGGCGCGCAGCGCGGTGATGGCGTACGACGCCACGGTGCTGGCCGGCACGCAGGG
CAAGCGCAATCACATCAAGACGGACCGCATCGTCGAGGTGGCGCTCCGTGACGAACTGCCGCTCGTGCTGTTTGCCGAAG
GCGGCGGCGGGCGGCCTGGTGACGTGGATTTTCCGTCCGTCTCCGGCCTGTATCAGCCGTCGTTCGCGGCGTTTGCCGAA
CTCAGCGGACACGTGCCGGTGGTCGGCATCGTGTCGGGCCGTTGCTTTGCCGGCAATGCCGCGTTCCTGGGCTGCTGCGA
CGTGATCATTGCCGATCGCTCGGCGAACATCGGCATGGCCGGGCCGGCCATGATCGAGGGCGGTGGCCTTGGCATCTTCC
GTCCGGAAGACGTGGGTCCCGCGTCGGTGCAGTTCGCCAATGGCGTGGTCGACGTGCTGGTCGAGAATGAGGCCGAGGCC
GTGGTGGTCGCCAAGCACTACCTGTCGATGTTCCAGGGCCGCGTGACGCACTGGAGCGCGCCTGACGCGCTGGCGTTGCG
CCAGGTCGTGCCCGAGAACCGCCTGCGCGTGTACGACACCCGCAAGGCCATCGAAGGCATCGCCGACGTCGGCAGCGTGC
TGATGCTGCGCGGCGGGTTCGGCGCGGGCATTCACACCGCACTGGCCCGTGTGGAGGGGCAGCCGGTCGGCATCATGGCC
AACAACCCGTATCACCTTGGTGGCGCGATCGACGCGGATGCCGCGGACAAGGCAACGCGTTTCATGCAACTCTGCGATGC
GCATGGCTTGCCGATCATCTCGCTGATTGATACCCCGGGGTTCATGGTCGGACCCGAGATCGAGGCCCAGGCCCAGGTGC
GTCACGTGTCGCGGATGTTCCTGGCTGCTGCCAAGCTGCGCGTGGCGCTGCTGGCCGTCACGCTGCGCAAGGGCTACGGC
CTCGGCGCGATGGCGATGGCAGGCGGTGGCTTCCGCTCGGCAAACTTCACGATCTCGTGGCCGACCGGCGAATTCGGTCC
GATGGGGCTGGAGGGCGCGGTCAGGCTCGGCTTCAAGAAGGAACTCGAAGCGGTGCCCGATGGCCCGGAGCGCAAGGCGC
TGTTCGACAAACTGGTGGCGCAGTCCTACGAGCGTGGCCACGCGATCAACACGGCCGCTGCAGTGGAGATCGATGCCGTG
ATCGACCCGGCCGAGACGCGCAAATGGATCGCCCAGGGCATTGCCTCGGCCGACGTTCGCAGCCGCAGGGCGCGCCAGTC
GTTCGTCGATGCATGGTGA

Upstream 100 bases:

>100_bases
CCGCGCGACGACGCGCACGCTCCCATGCCTGTTCTGGCAGGGTGGCCACGCCGTGCTCGGTAATCGGTGCGGTATCGGTC
GCCATGCTCATCTCGCTTTG

Downstream 100 bases:

>100_bases
GCGTGGTGATTGTCACTGTGATGAGTGAAACGCGGGCACTGTTCGGCAGGCCCGATCCACGTCCACACGCGAGGGATTCA
AGATGAAGGATGCTGCTGCC

Product: putative carbamoyl-phosphate synthase L chain, ATP-binding

Products: NA

Alternate protein names: Pyruvic carboxylase; PYC [H]

Number of amino acids: Translated: 1152; Mature: 1152

Protein sequence:

>1152_residues
MHTSIEHRRVSCRGVLISGCQEPYAQEASNRAEWCSRLLKMTTELKKLLIANRGEIALRVQRAARDLDIGTVAVYSQDDA
GCRHRMLADEAIALDGAGPAAYIDIAGIIAAAKASGSDAVHPGYGFLSERADFAQACIDAGIRFIGPTVEHLALFGDKGR
ALQLAAECDVPVMPATHGGASLEEIERFFDAQGDAGIVIKAVGGGGGRGMRVVRRREDLAEAYARCRSEASSAFGVDALY
AERLVSRARHIEVQIAGDGQHVIALGERDCTLQRRFQKLVEIAPSPVLKPELRAEIIKAALRLARRVNYQSLGTFEFLVE
ESESGEQKRFVFIEANPRLQVEHTITEQVTGVDLVALQIGLASGRTLVELGLDPASPPQPRGYAIQVRVNAEMTDAQGLA
RPAFGRLERFEPPAGPDVRVDSHGYAGYEPSPNFDTLLAKLIVSSAAPGFEAAVRRLQRSLAEFRIVGVPTNLNLLRALA
QREDFLTQDVHTRLFESILPALMASAETIAEAERAQDARFGGASHATPVHASHATRAPEAEEELEEGLVAIRAPLTGRVV
DIPVQLDEIVKPGQTVAVLDAMKMEHAIVAPCAGRVVDLRPEKGALVSEGHMLIVLEQAEADGVAVDAARNVDPNAIRAD
LQRVLDRHAYLYDAARPDAVAKRRSRGQRTARENIADLCDGDSFVEYGALALAAQASRRSKEDLIVNTPADGLITGIGEI
NRELVAKERARSAVMAYDATVLAGTQGKRNHIKTDRIVEVALRDELPLVLFAEGGGGRPGDVDFPSVSGLYQPSFAAFAE
LSGHVPVVGIVSGRCFAGNAAFLGCCDVIIADRSANIGMAGPAMIEGGGLGIFRPEDVGPASVQFANGVVDVLVENEAEA
VVVAKHYLSMFQGRVTHWSAPDALALRQVVPENRLRVYDTRKAIEGIADVGSVLMLRGGFGAGIHTALARVEGQPVGIMA
NNPYHLGGAIDADAADKATRFMQLCDAHGLPIISLIDTPGFMVGPEIEAQAQVRHVSRMFLAAAKLRVALLAVTLRKGYG
LGAMAMAGGGFRSANFTISWPTGEFGPMGLEGAVRLGFKKELEAVPDGPERKALFDKLVAQSYERGHAINTAAAVEIDAV
IDPAETRKWIAQGIASADVRSRRARQSFVDAW

Sequences:

>Translated_1152_residues
MHTSIEHRRVSCRGVLISGCQEPYAQEASNRAEWCSRLLKMTTELKKLLIANRGEIALRVQRAARDLDIGTVAVYSQDDA
GCRHRMLADEAIALDGAGPAAYIDIAGIIAAAKASGSDAVHPGYGFLSERADFAQACIDAGIRFIGPTVEHLALFGDKGR
ALQLAAECDVPVMPATHGGASLEEIERFFDAQGDAGIVIKAVGGGGGRGMRVVRRREDLAEAYARCRSEASSAFGVDALY
AERLVSRARHIEVQIAGDGQHVIALGERDCTLQRRFQKLVEIAPSPVLKPELRAEIIKAALRLARRVNYQSLGTFEFLVE
ESESGEQKRFVFIEANPRLQVEHTITEQVTGVDLVALQIGLASGRTLVELGLDPASPPQPRGYAIQVRVNAEMTDAQGLA
RPAFGRLERFEPPAGPDVRVDSHGYAGYEPSPNFDTLLAKLIVSSAAPGFEAAVRRLQRSLAEFRIVGVPTNLNLLRALA
QREDFLTQDVHTRLFESILPALMASAETIAEAERAQDARFGGASHATPVHASHATRAPEAEEELEEGLVAIRAPLTGRVV
DIPVQLDEIVKPGQTVAVLDAMKMEHAIVAPCAGRVVDLRPEKGALVSEGHMLIVLEQAEADGVAVDAARNVDPNAIRAD
LQRVLDRHAYLYDAARPDAVAKRRSRGQRTARENIADLCDGDSFVEYGALALAAQASRRSKEDLIVNTPADGLITGIGEI
NRELVAKERARSAVMAYDATVLAGTQGKRNHIKTDRIVEVALRDELPLVLFAEGGGGRPGDVDFPSVSGLYQPSFAAFAE
LSGHVPVVGIVSGRCFAGNAAFLGCCDVIIADRSANIGMAGPAMIEGGGLGIFRPEDVGPASVQFANGVVDVLVENEAEA
VVVAKHYLSMFQGRVTHWSAPDALALRQVVPENRLRVYDTRKAIEGIADVGSVLMLRGGFGAGIHTALARVEGQPVGIMA
NNPYHLGGAIDADAADKATRFMQLCDAHGLPIISLIDTPGFMVGPEIEAQAQVRHVSRMFLAAAKLRVALLAVTLRKGYG
LGAMAMAGGGFRSANFTISWPTGEFGPMGLEGAVRLGFKKELEAVPDGPERKALFDKLVAQSYERGHAINTAAAVEIDAV
IDPAETRKWIAQGIASADVRSRRARQSFVDAW
>Mature_1152_residues
MHTSIEHRRVSCRGVLISGCQEPYAQEASNRAEWCSRLLKMTTELKKLLIANRGEIALRVQRAARDLDIGTVAVYSQDDA
GCRHRMLADEAIALDGAGPAAYIDIAGIIAAAKASGSDAVHPGYGFLSERADFAQACIDAGIRFIGPTVEHLALFGDKGR
ALQLAAECDVPVMPATHGGASLEEIERFFDAQGDAGIVIKAVGGGGGRGMRVVRRREDLAEAYARCRSEASSAFGVDALY
AERLVSRARHIEVQIAGDGQHVIALGERDCTLQRRFQKLVEIAPSPVLKPELRAEIIKAALRLARRVNYQSLGTFEFLVE
ESESGEQKRFVFIEANPRLQVEHTITEQVTGVDLVALQIGLASGRTLVELGLDPASPPQPRGYAIQVRVNAEMTDAQGLA
RPAFGRLERFEPPAGPDVRVDSHGYAGYEPSPNFDTLLAKLIVSSAAPGFEAAVRRLQRSLAEFRIVGVPTNLNLLRALA
QREDFLTQDVHTRLFESILPALMASAETIAEAERAQDARFGGASHATPVHASHATRAPEAEEELEEGLVAIRAPLTGRVV
DIPVQLDEIVKPGQTVAVLDAMKMEHAIVAPCAGRVVDLRPEKGALVSEGHMLIVLEQAEADGVAVDAARNVDPNAIRAD
LQRVLDRHAYLYDAARPDAVAKRRSRGQRTARENIADLCDGDSFVEYGALALAAQASRRSKEDLIVNTPADGLITGIGEI
NRELVAKERARSAVMAYDATVLAGTQGKRNHIKTDRIVEVALRDELPLVLFAEGGGGRPGDVDFPSVSGLYQPSFAAFAE
LSGHVPVVGIVSGRCFAGNAAFLGCCDVIIADRSANIGMAGPAMIEGGGLGIFRPEDVGPASVQFANGVVDVLVENEAEA
VVVAKHYLSMFQGRVTHWSAPDALALRQVVPENRLRVYDTRKAIEGIADVGSVLMLRGGFGAGIHTALARVEGQPVGIMA
NNPYHLGGAIDADAADKATRFMQLCDAHGLPIISLIDTPGFMVGPEIEAQAQVRHVSRMFLAAAKLRVALLAVTLRKGYG
LGAMAMAGGGFRSANFTISWPTGEFGPMGLEGAVRLGFKKELEAVPDGPERKALFDKLVAQSYERGHAINTAAAVEIDAV
IDPAETRKWIAQGIASADVRSRRARQSFVDAW

Specific function: Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second, leading to oxaloacetate production. Fulfills an anaplerotic functi

COG id: COG4799

COG function: function code I; Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 carboxyltransferase domain [H]

Homologues:

Organism=Homo sapiens, GI106049528, Length=457, Percent_Identity=46.6083150984683, Blast_Score=343, Evalue=5e-94,
Organism=Homo sapiens, GI106049295, Length=457, Percent_Identity=46.6083150984683, Blast_Score=343, Evalue=5e-94,
Organism=Homo sapiens, GI106049292, Length=457, Percent_Identity=46.6083150984683, Blast_Score=343, Evalue=5e-94,
Organism=Homo sapiens, GI116805327, Length=495, Percent_Identity=37.979797979798, Blast_Score=303, Evalue=4e-82,
Organism=Homo sapiens, GI189095269, Length=486, Percent_Identity=37.2427983539095, Blast_Score=263, Evalue=9e-70,
Organism=Homo sapiens, GI295821183, Length=463, Percent_Identity=38.0129589632829, Blast_Score=261, Evalue=3e-69,
Organism=Homo sapiens, GI65506442, Length=461, Percent_Identity=38.177874186551, Blast_Score=260, Evalue=4e-69,
Organism=Homo sapiens, GI38679960, Length=432, Percent_Identity=29.1666666666667, Blast_Score=155, Evalue=3e-37,
Organism=Homo sapiens, GI38679974, Length=432, Percent_Identity=29.1666666666667, Blast_Score=155, Evalue=3e-37,
Organism=Homo sapiens, GI38679977, Length=432, Percent_Identity=29.1666666666667, Blast_Score=155, Evalue=3e-37,
Organism=Homo sapiens, GI38679967, Length=432, Percent_Identity=29.1666666666667, Blast_Score=155, Evalue=3e-37,
Organism=Homo sapiens, GI38679971, Length=432, Percent_Identity=29.1666666666667, Blast_Score=154, Evalue=3e-37,
Organism=Homo sapiens, GI134142062, Length=518, Percent_Identity=28.3783783783784, Blast_Score=151, Evalue=3e-36,
Organism=Homo sapiens, GI119943100, Length=438, Percent_Identity=26.027397260274, Blast_Score=135, Evalue=3e-31,
Organism=Homo sapiens, GI295821216, Length=447, Percent_Identity=26.3982102908277, Blast_Score=129, Evalue=2e-29,
Organism=Homo sapiens, GI11545863, Length=483, Percent_Identity=26.7080745341615, Blast_Score=128, Evalue=3e-29,
Organism=Escherichia coli, GI1789654, Length=464, Percent_Identity=40.948275862069, Blast_Score=294, Evalue=2e-80,
Organism=Caenorhabditis elegans, GI17562816, Length=457, Percent_Identity=45.5142231947484, Blast_Score=329, Evalue=4e-90,
Organism=Caenorhabditis elegans, GI71987519, Length=482, Percent_Identity=37.344398340249, Blast_Score=281, Evalue=1e-75,
Organism=Caenorhabditis elegans, GI17567343, Length=465, Percent_Identity=38.9247311827957, Blast_Score=273, Evalue=3e-73,
Organism=Caenorhabditis elegans, GI71997168, Length=512, Percent_Identity=27.1484375, Blast_Score=164, Evalue=2e-40,
Organism=Caenorhabditis elegans, GI71997163, Length=512, Percent_Identity=27.1484375, Blast_Score=164, Evalue=3e-40,
Organism=Caenorhabditis elegans, GI17552936, Length=489, Percent_Identity=28.2208588957055, Blast_Score=155, Evalue=2e-37,
Organism=Caenorhabditis elegans, GI133931226, Length=377, Percent_Identity=30.5039787798408, Blast_Score=151, Evalue=2e-36,
Organism=Caenorhabditis elegans, GI25147359, Length=487, Percent_Identity=26.4887063655031, Blast_Score=148, Evalue=2e-35,
Organism=Caenorhabditis elegans, GI25147362, Length=487, Percent_Identity=26.4887063655031, Blast_Score=148, Evalue=2e-35,
Organism=Saccharomyces cerevisiae, GI6319695, Length=481, Percent_Identity=41.7879417879418, Blast_Score=314, Evalue=6e-86,
Organism=Saccharomyces cerevisiae, GI6321376, Length=486, Percent_Identity=41.5637860082305, Blast_Score=301, Evalue=3e-82,
Organism=Saccharomyces cerevisiae, GI6319685, Length=460, Percent_Identity=37.3913043478261, Blast_Score=276, Evalue=2e-74,
Organism=Saccharomyces cerevisiae, GI6324343, Length=532, Percent_Identity=28.0075187969925, Blast_Score=155, Evalue=4e-38,
Organism=Saccharomyces cerevisiae, GI6323863, Length=402, Percent_Identity=29.8507462686567, Blast_Score=150, Evalue=9e-37,
Organism=Drosophila melanogaster, GI24652212, Length=463, Percent_Identity=47.3002159827214, Blast_Score=348, Evalue=2e-95,
Organism=Drosophila melanogaster, GI24652210, Length=463, Percent_Identity=47.3002159827214, Blast_Score=348, Evalue=2e-95,
Organism=Drosophila melanogaster, GI24652214, Length=463, Percent_Identity=47.3002159827214, Blast_Score=348, Evalue=2e-95,
Organism=Drosophila melanogaster, GI19921944, Length=463, Percent_Identity=47.3002159827214, Blast_Score=348, Evalue=2e-95,
Organism=Drosophila melanogaster, GI24652216, Length=463, Percent_Identity=47.3002159827214, Blast_Score=348, Evalue=2e-95,
Organism=Drosophila melanogaster, GI281363050, Length=463, Percent_Identity=47.3002159827214, Blast_Score=347, Evalue=2e-95,
Organism=Drosophila melanogaster, GI24652224, Length=463, Percent_Identity=47.3002159827214, Blast_Score=347, Evalue=2e-95,
Organism=Drosophila melanogaster, GI24652222, Length=463, Percent_Identity=47.3002159827214, Blast_Score=347, Evalue=2e-95,
Organism=Drosophila melanogaster, GI24652220, Length=463, Percent_Identity=47.3002159827214, Blast_Score=347, Evalue=2e-95,
Organism=Drosophila melanogaster, GI24652218, Length=463, Percent_Identity=47.3002159827214, Blast_Score=347, Evalue=2e-95,
Organism=Drosophila melanogaster, GI24651757, Length=476, Percent_Identity=38.655462184874, Blast_Score=285, Evalue=2e-76,
Organism=Drosophila melanogaster, GI24651759, Length=437, Percent_Identity=37.2997711670481, Blast_Score=248, Evalue=2e-65,
Organism=Drosophila melanogaster, GI161076409, Length=429, Percent_Identity=28.9044289044289, Blast_Score=152, Evalue=2e-36,
Organism=Drosophila melanogaster, GI161076407, Length=429, Percent_Identity=28.9044289044289, Blast_Score=152, Evalue=2e-36,
Organism=Drosophila melanogaster, GI24586460, Length=429, Percent_Identity=28.9044289044289, Blast_Score=152, Evalue=2e-36,
Organism=Drosophila melanogaster, GI24586458, Length=429, Percent_Identity=28.9044289044289, Blast_Score=152, Evalue=2e-36,
Organism=Drosophila melanogaster, GI24586065, Length=545, Percent_Identity=25.8715596330275, Blast_Score=126, Evalue=8e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR011761
- InterPro:   IPR013815
- InterPro:   IPR013816
- InterPro:   IPR011764
- InterPro:   IPR005482
- InterPro:   IPR000089
- InterPro:   IPR005479
- InterPro:   IPR005481
- InterPro:   IPR003379
- InterPro:   IPR013817
- InterPro:   IPR016185
- InterPro:   IPR000891
- InterPro:   IPR005930
- InterPro:   IPR011054
- InterPro:   IPR011053 [H]

Pfam domain/function: PF02785 Biotin_carb_C; PF00364 Biotin_lipoyl; PF00289 CPSase_L_chain; PF02786 CPSase_L_D2; PF00682 HMGL-like; PF02436 PYC_OADA [H]

EC number: =6.4.1.1 [H]

Molecular weight: Translated: 123360; Mature: 123360

Theoretical pI: Translated: 6.02; Mature: 6.02

Prosite motif: PS50975 ATP_GRASP ; PS00867 CPSASE_2 ; PS50979 BC ; PS50980 COA_CT_NTER ; PS50989 COA_CT_CTER ; PS50968 BIOTINYL_LIPOYL ; PS00188 BIOTIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHTSIEHRRVSCRGVLISGCQEPYAQEASNRAEWCSRLLKMTTELKKLLIANRGEIALRV
CCCCCCCCEEEECEEEECCCCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEE
QRAARDLDIGTVAVYSQDDAGCRHRMLADEAIALDGAGPAAYIDIAGIIAAAKASGSDAV
EHHHCCCCCCEEEEEECCCCCHHHHHHHHHHEEECCCCCCHHHHHHHHHHHHCCCCCCCC
HPGYGFLSERADFAQACIDAGIRFIGPTVEHLALFGDKGRALQLAAECDVPVMPATHGGA
CCCCCHHHHHHHHHHHHHHCCHHHCCCCHHHHHHCCCCCCEEEEEECCCCCCCCCCCCCC
SLEEIERFFDAQGDAGIVIKAVGGGGGRGMRVVRRREDLAEAYARCRSEASSAFGVDALY
CHHHHHHHHCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHH
AERLVSRARHIEVQIAGDGQHVIALGERDCTLQRRFQKLVEIAPSPVLKPELRAEIIKAA
HHHHHHHHHEEEEEEECCCCEEEEECCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHH
LRLARRVNYQSLGTFEFLVEESESGEQKRFVFIEANPRLQVEHTITEQVTGVDLVALQIG
HHHHHHCCHHHCCCEEEEEECCCCCCCEEEEEEECCCCEEEEEEHHHHHCCCEEEEEEEE
LASGRTLVELGLDPASPPQPRGYAIQVRVNAEMTDAQGLARPAFGRLERFEPPAGPDVRV
CCCCCEEEEECCCCCCCCCCCCEEEEEEECCCCCCCCCCCCHHHHHHHHCCCCCCCCEEE
DSHGYAGYEPSPNFDTLLAKLIVSSAAPGFEAAVRRLQRSLAEFRIVGVPTNLNLLRALA
CCCCCCCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHEEEEECCCCHHHHHHHH
QREDFLTQDVHTRLFESILPALMASAETIAEAERAQDARFGGASHATPVHASHATRAPEA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCH
EEELEEGLVAIRAPLTGRVVDIPVQLDEIVKPGQTVAVLDAMKMEHAIVAPCAGRVVDLR
HHHHHCCCEEEECCCCCCEEEECCCHHHHCCCCCEEEHHHHHHHCCCEECCCCCCEEEEC
PEKGALVSEGHMLIVLEQAEADGVAVDAARNVDPNAIRADLQRVLDRHAYLYDAARPDAV
CCCCCEEECCCEEEEEEECCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHH
AKRRSRGQRTARENIADLCDGDSFVEYGALALAAQASRRSKEDLIVNTPADGLITGIGEI
HHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCEEEECCCCHHHHHHHHH
NRELVAKERARSAVMAYDATVLAGTQGKRNHIKTDRIVEVALRDELPLVLFAEGGGGRPG
HHHHHHHHHHHHHHHEECEEEEECCCCCCCCCCHHHEEEEEECCCCCEEEEECCCCCCCC
DVDFPSVSGLYQPSFAAFAELSGHVPVVGIVSGRCFAGNAAFLGCCDVIIADRSANIGMA
CCCCCCCCCCCCCCHHHHHHHCCCCCEEEEECCCEEECCCHHHEEEEEEEECCCCCCCCC
GPAMIEGGGLGIFRPEDVGPASVQFANGVVDVLVENEAEAVVVAKHYLSMFQGRVTHWSA
CCCEEECCCEEEECCCCCCCCCEEHHCCEEEEEECCCCCEEEHHHHHHHHHHCCCCCCCC
PDALALRQVVPENRLRVYDTRKAIEGIADVGSVLMLRGGFGAGIHTALARVEGQPVGIMA
CHHHHHHHHCCCCCEEEEHHHHHHHHHHHHHHHEEEECCCCCHHHHHHHHHCCCCEEEEE
NNPYHLGGAIDADAADKATRFMQLCDAHGLPIISLIDTPGFMVGPEIEAQAQVRHVSRMF
CCCEEECCCCCCCHHHHHHHHHHHHHCCCCCEEEEECCCCCEECCCCCHHHHHHHHHHHH
LAAAKLRVALLAVTLRKGYGLGAMAMAGGGFRSANFTISWPTGEFGPMGLEGAVRLGFKK
HHHHHHHHHHHHHHHHCCCCCCHHHHCCCCCCCCCEEEECCCCCCCCCCCCHHEECCCHH
ELEAVPDGPERKALFDKLVAQSYERGHAINTAAAVEIDAVIDPAETRKWIAQGIASADVR
HHHCCCCCCHHHHHHHHHHHHHHHCCCCCCCEEEEEEEEEECCHHHHHHHHHHHHHHHHH
SRRARQSFVDAW
HHHHHHHHHCCC
>Mature Secondary Structure
MHTSIEHRRVSCRGVLISGCQEPYAQEASNRAEWCSRLLKMTTELKKLLIANRGEIALRV
CCCCCCCCEEEECEEEECCCCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEE
QRAARDLDIGTVAVYSQDDAGCRHRMLADEAIALDGAGPAAYIDIAGIIAAAKASGSDAV
EHHHCCCCCCEEEEEECCCCCHHHHHHHHHHEEECCCCCCHHHHHHHHHHHHCCCCCCCC
HPGYGFLSERADFAQACIDAGIRFIGPTVEHLALFGDKGRALQLAAECDVPVMPATHGGA
CCCCCHHHHHHHHHHHHHHCCHHHCCCCHHHHHHCCCCCCEEEEEECCCCCCCCCCCCCC
SLEEIERFFDAQGDAGIVIKAVGGGGGRGMRVVRRREDLAEAYARCRSEASSAFGVDALY
CHHHHHHHHCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHH
AERLVSRARHIEVQIAGDGQHVIALGERDCTLQRRFQKLVEIAPSPVLKPELRAEIIKAA
HHHHHHHHHEEEEEEECCCCEEEEECCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHH
LRLARRVNYQSLGTFEFLVEESESGEQKRFVFIEANPRLQVEHTITEQVTGVDLVALQIG
HHHHHHCCHHHCCCEEEEEECCCCCCCEEEEEEECCCCEEEEEEHHHHHCCCEEEEEEEE
LASGRTLVELGLDPASPPQPRGYAIQVRVNAEMTDAQGLARPAFGRLERFEPPAGPDVRV
CCCCCEEEEECCCCCCCCCCCCEEEEEEECCCCCCCCCCCCHHHHHHHHCCCCCCCCEEE
DSHGYAGYEPSPNFDTLLAKLIVSSAAPGFEAAVRRLQRSLAEFRIVGVPTNLNLLRALA
CCCCCCCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHEEEEECCCCHHHHHHHH
QREDFLTQDVHTRLFESILPALMASAETIAEAERAQDARFGGASHATPVHASHATRAPEA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCH
EEELEEGLVAIRAPLTGRVVDIPVQLDEIVKPGQTVAVLDAMKMEHAIVAPCAGRVVDLR
HHHHHCCCEEEECCCCCCEEEECCCHHHHCCCCCEEEHHHHHHHCCCEECCCCCCEEEEC
PEKGALVSEGHMLIVLEQAEADGVAVDAARNVDPNAIRADLQRVLDRHAYLYDAARPDAV
CCCCCEEECCCEEEEEEECCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHH
AKRRSRGQRTARENIADLCDGDSFVEYGALALAAQASRRSKEDLIVNTPADGLITGIGEI
HHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCEEEECCCCHHHHHHHHH
NRELVAKERARSAVMAYDATVLAGTQGKRNHIKTDRIVEVALRDELPLVLFAEGGGGRPG
HHHHHHHHHHHHHHHEECEEEEECCCCCCCCCCHHHEEEEEECCCCCEEEEECCCCCCCC
DVDFPSVSGLYQPSFAAFAELSGHVPVVGIVSGRCFAGNAAFLGCCDVIIADRSANIGMA
CCCCCCCCCCCCCCHHHHHHHCCCCCEEEEECCCEEECCCHHHEEEEEEEECCCCCCCCC
GPAMIEGGGLGIFRPEDVGPASVQFANGVVDVLVENEAEAVVVAKHYLSMFQGRVTHWSA
CCCEEECCCEEEECCCCCCCCCEEHHCCEEEEEECCCCCEEEHHHHHHHHHHCCCCCCCC
PDALALRQVVPENRLRVYDTRKAIEGIADVGSVLMLRGGFGAGIHTALARVEGQPVGIMA
CHHHHHHHHCCCCCEEEEHHHHHHHHHHHHHHHEEEECCCCCHHHHHHHHHCCCCEEEEE
NNPYHLGGAIDADAADKATRFMQLCDAHGLPIISLIDTPGFMVGPEIEAQAQVRHVSRMF
CCCEEECCCCCCCHHHHHHHHHHHHHCCCCCEEEEECCCCCEECCCCCHHHHHHHHHHHH
LAAAKLRVALLAVTLRKGYGLGAMAMAGGGFRSANFTISWPTGEFGPMGLEGAVRLGFKK
HHHHHHHHHHHHHHHHCCCCCCHHHHCCCCCCCCCEEEECCCCCCCCCCCCHHEECCCHH
ELEAVPDGPERKALFDKLVAQSYERGHAINTAAAVEIDAVIDPAETRKWIAQGIASADVR
HHHCCCCCCHHHHHHHHHHHHHHHCCCCCCCEEEEEEEEEECCHHHHHHHHHHHHHHHHH
SRRARQSFVDAW
HHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]