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The map label for this gene is ygfH [H]

Identifier: 94313817

GI number: 94313817

Start: 1559288

End: 1560820

Strand: Direct

Name: ygfH [H]

Synonym: Rmet_4895

Alternate gene names: 94313817

Gene position: 1559288-1560820 (Clockwise)

Preceding gene: 94313814

Following gene: 94313819

Centisome position: 60.44

GC content: 63.8

Gene sequence:

>1533_bases
ATGTACCGCGATCGCATTCGCCTGGCAGACCTGCAGAACAGGATCATGTCGGCCGATCAAGCTGCAGCACTGATTCAGGA
TGGCATGACGGTAGGGATGAGCGGGTTCACCCGCGCAGGCGACTGCAAGGCCGTACCGGTGGCGCTGGCGCGCCGCGCTG
CCACCGATCCGCTGCAGATCACGCTGATCACGGGCGCATCTCTCGGTAACGACACCGACAAGATCCTGGCGGAGAGCAAT
GTGCTTGCCCGCCGCCTGCCTTTCCAGTCCGACTCCACGCTGCGCCGCAAGATCAACGACGGCGAGGTGATGTTTATCGA
CCAGCATCTGGGTGAAACCGTCGAGCAACTGCGCAGCGGCCAGATCGCACCCGTCGATATCGCGGTTATCGAAGCCACGG
CTATCACCGAGACGGGTGGCATCGTGCCCACCACGTCGGTCGGCAACTCCGCCAGCTTCGCGATGATGGCGAAGAAGGTG
ATCGTCGAACTGAACCTGAACATGCCGACCGGGCTGGAGGGACTGCATGACATCGCGTTCCCGGTACAACGCCCATATCG
CCAGCCGATTCCATTGATCGCCGTCGAGCAACGCATCGGCCTGCCGTACATCCCCGTCGATCCGTCGCGCATCGCCGCGA
TCGTGATCACCCAGCGCGACGACAGCCCATCGAACGCGCTGCCGCCCGATGGCGAAACGCGCCAGATCGCCGGACACCTG
AATGCGCTGCTCGATCGTGAAGTGCGCGCCGGACGGCTCTCGACGTCGCTGCAGCCGCTGCAGGCCGGTATTGGCACGAT
CGCCAACGCCGTGCTGCACGGGCTGGCCGACTCGCCGTTCCACGACCTGACCATGTATTCGGAAGTCCTGCAGGACAGCA
CCATTGCGCTGATCGACGCGGGCAAGCTGCGCTTCGCCTCGGCATCGTCGATGACGCTGTCGGCACCCGTGTATCGTCGC
GTGCTCGATGATATCGAGCGCTACAAATCGCGTCTGATCCTGCGCCCGCAAGAGATCAGCAATCACCCCGAAGTGCTGCG
CCGCCTGGGCCTGATCACGATCAATACCGCGCTCGAGTGCGACATCTATGGCAACGTGAACTCGACGCACGTTGGCGGCA
CGCACATGATGAACGGTATCGGCGGCTCGGGCGATTTCGCGCGCAATGCGTACCTGTCGGTGTTCGTCACCAAATCGGTG
GCCAAGGACGGCAAGATCTCCAGCATCGTGCCGATGGTCTCGCACGTCGACAACAGCGAGCACGACGTCGATATCCTCGT
CACGGAACACGGGCTGGCCGACCTGCGCGGACTGGCACCGCGCGAGCGAGCGCTGCAGGTCATCAACAACTGCGCCGACC
CCGCCTACCGCGACGGGCTGCTCGACTACTTCCGCCGCGCCTGCCTCCGTGGAGGCCAGACGCCTCATCTGCTCGAGGAA
GCGTTCGCCTGGCATATCAACTACCGCGAACAAGGCACGATGCAGCCGCAGGGCCACGTTGGCAAGGCCGCCATCGAAGC
GCTGGCAGCCTAA

Upstream 100 bases:

>100_bases
CTACACTGTGCTGCGCGCCTGTTGACACGCAACGTCCGCCGCGATTCACAAGGTCCGCTGGCGGAGAACCAGACAGCCCC
CAAGCAAGCAAGGAGACGAG

Downstream 100 bases:

>100_bases
GCCAAGTAAGCTGGGGCCCTTCCTTCAGTCTTCCATCAACACCCGGAGCATCCGCTCCGGGTCGACCAGAAAGTCACGCG
TGATCTGGTAGTGCTCCGTG

Product: propionyl-CoA:succinate-CoA transferase

Products: propionate; succinyl-CoA [C]

Alternate protein names: NA

Number of amino acids: Translated: 510; Mature: 510

Protein sequence:

>510_residues
MYRDRIRLADLQNRIMSADQAAALIQDGMTVGMSGFTRAGDCKAVPVALARRAATDPLQITLITGASLGNDTDKILAESN
VLARRLPFQSDSTLRRKINDGEVMFIDQHLGETVEQLRSGQIAPVDIAVIEATAITETGGIVPTTSVGNSASFAMMAKKV
IVELNLNMPTGLEGLHDIAFPVQRPYRQPIPLIAVEQRIGLPYIPVDPSRIAAIVITQRDDSPSNALPPDGETRQIAGHL
NALLDREVRAGRLSTSLQPLQAGIGTIANAVLHGLADSPFHDLTMYSEVLQDSTIALIDAGKLRFASASSMTLSAPVYRR
VLDDIERYKSRLILRPQEISNHPEVLRRLGLITINTALECDIYGNVNSTHVGGTHMMNGIGGSGDFARNAYLSVFVTKSV
AKDGKISSIVPMVSHVDNSEHDVDILVTEHGLADLRGLAPRERALQVINNCADPAYRDGLLDYFRRACLRGGQTPHLLEE
AFAWHINYREQGTMQPQGHVGKAAIEALAA

Sequences:

>Translated_510_residues
MYRDRIRLADLQNRIMSADQAAALIQDGMTVGMSGFTRAGDCKAVPVALARRAATDPLQITLITGASLGNDTDKILAESN
VLARRLPFQSDSTLRRKINDGEVMFIDQHLGETVEQLRSGQIAPVDIAVIEATAITETGGIVPTTSVGNSASFAMMAKKV
IVELNLNMPTGLEGLHDIAFPVQRPYRQPIPLIAVEQRIGLPYIPVDPSRIAAIVITQRDDSPSNALPPDGETRQIAGHL
NALLDREVRAGRLSTSLQPLQAGIGTIANAVLHGLADSPFHDLTMYSEVLQDSTIALIDAGKLRFASASSMTLSAPVYRR
VLDDIERYKSRLILRPQEISNHPEVLRRLGLITINTALECDIYGNVNSTHVGGTHMMNGIGGSGDFARNAYLSVFVTKSV
AKDGKISSIVPMVSHVDNSEHDVDILVTEHGLADLRGLAPRERALQVINNCADPAYRDGLLDYFRRACLRGGQTPHLLEE
AFAWHINYREQGTMQPQGHVGKAAIEALAA
>Mature_510_residues
MYRDRIRLADLQNRIMSADQAAALIQDGMTVGMSGFTRAGDCKAVPVALARRAATDPLQITLITGASLGNDTDKILAESN
VLARRLPFQSDSTLRRKINDGEVMFIDQHLGETVEQLRSGQIAPVDIAVIEATAITETGGIVPTTSVGNSASFAMMAKKV
IVELNLNMPTGLEGLHDIAFPVQRPYRQPIPLIAVEQRIGLPYIPVDPSRIAAIVITQRDDSPSNALPPDGETRQIAGHL
NALLDREVRAGRLSTSLQPLQAGIGTIANAVLHGLADSPFHDLTMYSEVLQDSTIALIDAGKLRFASASSMTLSAPVYRR
VLDDIERYKSRLILRPQEISNHPEVLRRLGLITINTALECDIYGNVNSTHVGGTHMMNGIGGSGDFARNAYLSVFVTKSV
AKDGKISSIVPMVSHVDNSEHDVDILVTEHGLADLRGLAPRERALQVINNCADPAYRDGLLDYFRRACLRGGQTPHLLEE
AFAWHINYREQGTMQPQGHVGKAAIEALAA

Specific function: Forms succinyl-CoA from succinate and acetyl-CoA [H]

COG id: COG0427

COG function: function code C; Acetyl-CoA hydrolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acetyl-CoA hydrolase/transferase family [H]

Homologues:

Organism=Escherichia coli, GI1789287, Length=485, Percent_Identity=45.360824742268, Blast_Score=424, Evalue=1e-120,
Organism=Caenorhabditis elegans, GI17538151, Length=396, Percent_Identity=24.4949494949495, Blast_Score=70, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI32563853, Length=222, Percent_Identity=29.2792792792793, Blast_Score=68, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6319456, Length=520, Percent_Identity=44.2307692307692, Blast_Score=414, Evalue=1e-116,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003702
- InterPro:   IPR006472
- InterPro:   IPR017821 [H]

Pfam domain/function: PF02550 AcetylCoA_hydro; PF04223 CitF [H]

EC number: NA

Molecular weight: Translated: 55276; Mature: 55276

Theoretical pI: Translated: 6.40; Mature: 6.40

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYRDRIRLADLQNRIMSADQAAALIQDGMTVGMSGFTRAGDCKAVPVALARRAATDPLQI
CCCCHHHHHHHHHHHHHHHHHHHHHHCCCEECCCCCCCCCCCCHHHHHHHHHCCCCCEEE
TLITGASLGNDTDKILAESNVLARRLPFQSDSTLRRKINDGEVMFIDQHLGETVEQLRSG
EEEECCCCCCCHHHHHHHCCHHHHHCCCCCCCHHHHHCCCCCEEEEHHHHHHHHHHHHCC
QIAPVDIAVIEATAITETGGIVPTTSVGNSASFAMMAKKVIVELNLNMPTGLEGLHDIAF
CCCEEEEEEEEEEEEECCCCCCCCCCCCCCHHHHHHHEEEEEEEECCCCCCCCHHHHHHH
PVQRPYRQPIPLIAVEQRIGLPYIPVDPSRIAAIVITQRDDSPSNALPPDGETRQIAGHL
HHCCCCCCCCCEEEEHHHCCCCCCCCCCCCEEEEEEEECCCCCCCCCCCCCCHHHHHHHH
NALLDREVRAGRLSTSLQPLQAGIGTIANAVLHGLADSPFHDLTMYSEVLQDSTIALIDA
HHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCEEEEEC
GKLRFASASSMTLSAPVYRRVLDDIERYKSRLILRPQEISNHPEVLRRLGLITINTALEC
CCEEEECCCCCEECHHHHHHHHHHHHHHHHHEECCHHHHCCCHHHHHHCCEEEEECEEEE
DIYGNVNSTHVGGTHMMNGIGGSGDFARNAYLSVFVTKSVAKDGKISSIVPMVSHVDNSE
EEECCCCCCCCCCHHHHCCCCCCCCCHHCCEEEEEEEHHHCCCCCHHHHHHHHHHCCCCC
HDVDILVTEHGLADLRGLAPRERALQVINNCADPAYRDGLLDYFRRACLRGGQTPHLLEE
CCEEEEEECCCHHHHHCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCHHHHHH
AFAWHINYREQGTMQPQGHVGKAAIEALAA
HHHEEEEECCCCCCCCCCCCHHHHHHHHCC
>Mature Secondary Structure
MYRDRIRLADLQNRIMSADQAAALIQDGMTVGMSGFTRAGDCKAVPVALARRAATDPLQI
CCCCHHHHHHHHHHHHHHHHHHHHHHCCCEECCCCCCCCCCCCHHHHHHHHHCCCCCEEE
TLITGASLGNDTDKILAESNVLARRLPFQSDSTLRRKINDGEVMFIDQHLGETVEQLRSG
EEEECCCCCCCHHHHHHHCCHHHHHCCCCCCCHHHHHCCCCCEEEEHHHHHHHHHHHHCC
QIAPVDIAVIEATAITETGGIVPTTSVGNSASFAMMAKKVIVELNLNMPTGLEGLHDIAF
CCCEEEEEEEEEEEEECCCCCCCCCCCCCCHHHHHHHEEEEEEEECCCCCCCCHHHHHHH
PVQRPYRQPIPLIAVEQRIGLPYIPVDPSRIAAIVITQRDDSPSNALPPDGETRQIAGHL
HHCCCCCCCCCEEEEHHHCCCCCCCCCCCCEEEEEEEECCCCCCCCCCCCCCHHHHHHHH
NALLDREVRAGRLSTSLQPLQAGIGTIANAVLHGLADSPFHDLTMYSEVLQDSTIALIDA
HHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCEEEEEC
GKLRFASASSMTLSAPVYRRVLDDIERYKSRLILRPQEISNHPEVLRRLGLITINTALEC
CCEEEECCCCCEECHHHHHHHHHHHHHHHHHEECCHHHHCCCHHHHHHCCEEEEECEEEE
DIYGNVNSTHVGGTHMMNGIGGSGDFARNAYLSVFVTKSVAKDGKISSIVPMVSHVDNSE
EEECCCCCCCCCCHHHHCCCCCCCCCHHCCEEEEEEEHHHCCCCCHHHHHHHHHHCCCCC
HDVDILVTEHGLADLRGLAPRERALQVINNCADPAYRDGLLDYFRRACLRGGQTPHLLEE
CCEEEEEECCCHHHHHCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCHHHHHH
AFAWHINYREQGTMQPQGHVGKAAIEALAA
HHHEEEEECCCCCCCCCCCCHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: propionyl-CoA; succinate [C]

Specific reaction: propionyl-CoA + succinate = propionate + succinyl-CoA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8550525 [H]