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The map label for this gene is ccpA [H]

Identifier: 94313761

GI number: 94313761

Start: 1496247

End: 1497323

Strand: Direct

Name: ccpA [H]

Synonym: Rmet_4839

Alternate gene names: 94313761

Gene position: 1496247-1497323 (Clockwise)

Preceding gene: 94313757

Following gene: 94313762

Centisome position: 57.99

GC content: 66.3

Gene sequence:

>1077_bases
ATGGCGCCGTCCCGCCGAACCGTGTTGTCGCAAAGCGTTGCCTCCGCCGAGCCCGGTCATGGTGTGACACTGGCCGACGT
CGCCCTCGCGGCGAAGGTATCGCTGGCCACCGCCTCGCGTGTGTTCAGCCATCCGCAGCTCGTCAGGGAAACCACCGCCA
ACCGCGTTCACGAGGCCGCGCAGCGGCTGTCGTTCCGCCCCAACCTGCTCGGCGCCAAGCTGCGCGCGCAGCAGACCCGC
ATTCTCGGCGTCATGCTGCCCACGCTGGAAAACGCGGTATTCGCCGAATGCTGGCGCGGCATCGAGGAATCGGCGATGGT
CGCGGGCTACTCGCTGATGCTTGTGACGAGCGGTTACGACACCGAACGCGAGCGCGAGCGGATCGAATATCTGCTCCGTC
ATCGTGTCGACGGCATGGTGCTGACCGTTGCGGATGCCGCCCAGAGCCTTGTTCTCGACCAGCTCGACAAGGAGTCGGTG
CCCTACGTGCTGGCCTATAACCAGGTATCGCTCCCAGGCCGGCACTCGGTGTCCGTCGACAACCGCGCCAGTGCATGCGA
GGGCGTCAAGGCGCTGATCACCGCGGGCCACCAGCGCATCGCCGTGATCTCCGGCGCCTTCATGGCCTCCGATCGCGCGC
GGCAGCGCTTCGCGGGCTATGAGGACGCGATGCGCGCGCATGATTTGACGCCGCTCGCCCCGGTCTGCCTGCCCTCGCAC
ACAGCCAGCAATGCCATGCAGATTCGTGAACTGATGACGCGTGCCGACGCCCCCACCGCATTCTTCTGCACCAACGACCT
GCTGGCGATCGGCGTAATTTCCGATCTCAAGCGGCTGGGCCGCCGCGTGCCGGGCGACGTATCCGTGCTCGGATATGACG
GCATCGCGCTTGGCGCGCTGGTGGAGCCGCCGCTGGCCACCGTCATGCAGCCGAACGCCGAGATCGGCGCGCAAGCCGTT
CACCAGCTTTTGCAACGGCTCCAGCATCGCAACCTGAACCACGATGACGCAGCAGAAGGCGCTTTCCTGCTGCCACACAT
GCTGCGCCTTGACGGTACCGTCAGCGCGCCGCGATAA

Upstream 100 bases:

>100_bases
GCGGCATCGCAGCAACGGAAAACCTTGACGCCTGATTTTTCGGCGCTTCAATGAAAACGTTTTCATCGCTGCATGCCCCC
ACCCCCCGACGAGGAAGCCC

Downstream 100 bases:

>100_bases
AACCTGCCTACAAGCGCCATACGCACCACTTGCCGTCTCAACCTTCAACCAGGGAGCTTCACATGTCGACGCAATCCTTC
TGGCGCCGTCCGCTGCGCTG

Product: putative LacI family transcriptional regulator

Products: NA

Alternate protein names: Catabolite control protein [H]

Number of amino acids: Translated: 358; Mature: 357

Protein sequence:

>358_residues
MAPSRRTVLSQSVASAEPGHGVTLADVALAAKVSLATASRVFSHPQLVRETTANRVHEAAQRLSFRPNLLGAKLRAQQTR
ILGVMLPTLENAVFAECWRGIEESAMVAGYSLMLVTSGYDTERERERIEYLLRHRVDGMVLTVADAAQSLVLDQLDKESV
PYVLAYNQVSLPGRHSVSVDNRASACEGVKALITAGHQRIAVISGAFMASDRARQRFAGYEDAMRAHDLTPLAPVCLPSH
TASNAMQIRELMTRADAPTAFFCTNDLLAIGVISDLKRLGRRVPGDVSVLGYDGIALGALVEPPLATVMQPNAEIGAQAV
HQLLQRLQHRNLNHDDAAEGAFLLPHMLRLDGTVSAPR

Sequences:

>Translated_358_residues
MAPSRRTVLSQSVASAEPGHGVTLADVALAAKVSLATASRVFSHPQLVRETTANRVHEAAQRLSFRPNLLGAKLRAQQTR
ILGVMLPTLENAVFAECWRGIEESAMVAGYSLMLVTSGYDTERERERIEYLLRHRVDGMVLTVADAAQSLVLDQLDKESV
PYVLAYNQVSLPGRHSVSVDNRASACEGVKALITAGHQRIAVISGAFMASDRARQRFAGYEDAMRAHDLTPLAPVCLPSH
TASNAMQIRELMTRADAPTAFFCTNDLLAIGVISDLKRLGRRVPGDVSVLGYDGIALGALVEPPLATVMQPNAEIGAQAV
HQLLQRLQHRNLNHDDAAEGAFLLPHMLRLDGTVSAPR
>Mature_357_residues
APSRRTVLSQSVASAEPGHGVTLADVALAAKVSLATASRVFSHPQLVRETTANRVHEAAQRLSFRPNLLGAKLRAQQTRI
LGVMLPTLENAVFAECWRGIEESAMVAGYSLMLVTSGYDTERERERIEYLLRHRVDGMVLTVADAAQSLVLDQLDKESVP
YVLAYNQVSLPGRHSVSVDNRASACEGVKALITAGHQRIAVISGAFMASDRARQRFAGYEDAMRAHDLTPLAPVCLPSHT
ASNAMQIRELMTRADAPTAFFCTNDLLAIGVISDLKRLGRRVPGDVSVLGYDGIALGALVEPPLATVMQPNAEIGAQAVH
QLLQRLQHRNLNHDDAAEGAFLLPHMLRLDGTVSAPR

Specific function: Transcriptional regulator involved in both the repression of carbohydrate utilization genes such as the alpha- amylase (amyE) and the acetyl-coenzyme A synthetase (acsA); and in the positive regulation of genes involved in excretion of excess carbon such

COG id: COG1609

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lacI-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790369, Length=317, Percent_Identity=32.4921135646688, Blast_Score=163, Evalue=1e-41,
Organism=Escherichia coli, GI48994940, Length=333, Percent_Identity=31.8318318318318, Blast_Score=148, Evalue=5e-37,
Organism=Escherichia coli, GI1790194, Length=315, Percent_Identity=31.1111111111111, Blast_Score=145, Evalue=6e-36,
Organism=Escherichia coli, GI1789068, Length=306, Percent_Identity=32.6797385620915, Blast_Score=138, Evalue=6e-34,
Organism=Escherichia coli, GI1787948, Length=316, Percent_Identity=28.7974683544304, Blast_Score=131, Evalue=5e-32,
Organism=Escherichia coli, GI1790715, Length=326, Percent_Identity=27.3006134969325, Blast_Score=131, Evalue=8e-32,
Organism=Escherichia coli, GI1788474, Length=311, Percent_Identity=29.903536977492, Blast_Score=122, Evalue=5e-29,
Organism=Escherichia coli, GI1789202, Length=305, Percent_Identity=30.4918032786885, Blast_Score=121, Evalue=6e-29,
Organism=Escherichia coli, GI1786540, Length=341, Percent_Identity=28.7390029325513, Blast_Score=107, Evalue=1e-24,
Organism=Escherichia coli, GI1787906, Length=329, Percent_Identity=27.9635258358663, Blast_Score=100, Evalue=1e-22,
Organism=Escherichia coli, GI1787580, Length=318, Percent_Identity=24.8427672955975, Blast_Score=84, Evalue=1e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006377
- InterPro:   IPR000843
- InterPro:   IPR010982
- InterPro:   IPR001761 [H]

Pfam domain/function: PF00356 LacI; PF00532 Peripla_BP_1 [H]

EC number: NA

Molecular weight: Translated: 38748; Mature: 38617

Theoretical pI: Translated: 7.71; Mature: 7.71

Prosite motif: PS50932 HTH_LACI_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAPSRRTVLSQSVASAEPGHGVTLADVALAAKVSLATASRVFSHPQLVRETTANRVHEAA
CCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHH
QRLSFRPNLLGAKLRAQQTRILGVMLPTLENAVFAECWRGIEESAMVAGYSLMLVTSGYD
HHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCEEEEEEECCCC
TERERERIEYLLRHRVDGMVLTVADAAQSLVLDQLDKESVPYVLAYNQVSLPGRHSVSVD
CHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCCCCC
NRASACEGVKALITAGHQRIAVISGAFMASDRARQRFAGYEDAMRAHDLTPLAPVCLPSH
CHHHHHHHHHHHHHCCCCEEEEEHHHHHHHHHHHHHHCCHHHHHHHCCCCCCCCHHCCCC
TASNAMQIRELMTRADAPTAFFCTNDLLAIGVISDLKRLGRRVPGDVSVLGYDGIALGAL
CHHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHHHHCCCCCEEEEECCCEEEHHH
VEPPLATVMQPNAEIGAQAVHQLLQRLQHRNLNHDDAAEGAFLLPHMLRLDGTVSAPR
CCCCHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
APSRRTVLSQSVASAEPGHGVTLADVALAAKVSLATASRVFSHPQLVRETTANRVHEAA
CCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHH
QRLSFRPNLLGAKLRAQQTRILGVMLPTLENAVFAECWRGIEESAMVAGYSLMLVTSGYD
HHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCEEEEEEECCCC
TERERERIEYLLRHRVDGMVLTVADAAQSLVLDQLDKESVPYVLAYNQVSLPGRHSVSVD
CHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCCCCC
NRASACEGVKALITAGHQRIAVISGAFMASDRARQRFAGYEDAMRAHDLTPLAPVCLPSH
CHHHHHHHHHHHHHCCCCEEEEEHHHHHHHHHHHHHHCCHHHHHHHCCCCCCCCHHCCCC
TASNAMQIRELMTRADAPTAFFCTNDLLAIGVISDLKRLGRRVPGDVSVLGYDGIALGAL
CHHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHHHHCCCCCEEEEECCCEEEHHH
VEPPLATVMQPNAEIGAQAVHQLLQRLQHRNLNHDDAAEGAFLLPHMLRLDGTVSAPR
CCCCHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8200532 [H]