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The map label for this gene is gntT [H]

Identifier: 94313696

GI number: 94313696

Start: 1418514

End: 1419875

Strand: Direct

Name: gntT [H]

Synonym: Rmet_4774

Alternate gene names: 94313696

Gene position: 1418514-1419875 (Clockwise)

Preceding gene: 94313695

Following gene: 94313697

Centisome position: 54.98

GC content: 64.17

Gene sequence:

>1362_bases
ATGGGTGCCGTTACAGGAACCACGCTCTTGGTCTATGCGCTGATCGCCGTGATCGCGCTGGTGATCCTGATCGCCAAATT
CAAACTGAACCCATTCATCACGCTCGTGGTGGTCTCGGTGGCGCTGGGCTTCGCCGTGGGGATGCCGATGGGCGACATCA
TCAAGTCGTTCGAAGCGGGTGTCGGCGGCACGCTCGGGCATATCGCGCTCGTGATCGGGCTCGGCACGATGCTTGGCAAG
ATGATGGCCGAATCGGGCGGCGCCGAGCGCATCGCGCTGACGCTGGTCGACTTCTTCGGCGAGAAGAACGTGCACTGGGC
GATGGTGGTCATCGCCTTCATCGTCGGCCTGCCGGTGTTCTTCGAGGTAGGCTTCGTGCTGCTCGTCCCGATCGCCTTCA
ACGTCGCCAAGCGCACCAATACCTCGATGGTGCTGGTTGGCATCCCGATGGTCGCCGGCCTCTCGGTGGTGCACGGGCTG
ATTCCGCCGCACCCTGCCGCGCTGCTGGCTGTGCAGGCCTACGGCGCTGACATGGGCAAGACGATCATGTACGCGCTGAT
CGTCGGTGTCCCGACAGCCGCCATCGCTGGCCCGCTGTTCGCCAAGCTGATCGACCGCCACGTGAAGCTGCCCGAGGTCA
ACCCGCTGGCCGCGCAGTTCACCGAAGAAGCCGAGAACATCAAGGCCACGCGCCAATTGCCAGGCTTCGGCATCACTGTC
TTCACGATCCTGCTGCCGGTGATTCTGATGCTGATTGGTAGCTGGGCGGACCTGATTGCCACGCCGAAGACCTTCGCCAA
CGACTTCCTCAAGCTGATCGGTAACTCGGTCATGGCACTGCTGATCGCCGCGCTGGTCAGCTTCTATACCTTCGGCAAGG
CCCGCGGCTTCGGTCGCGATGCGATCCTGAAGTTCACCAACGAGTGCGTGGCGCCGACCGCCATCATCACCCTCGTGGTG
GGTGCCGGCGGTGGCTTCGGCCGCATCCTGCGCGACTCCGGCATCTCCACCGCCATCGTCGACGTGGCAACCCACGCAAA
CGTCTCGGTGCTGGTATTGGGCTGGCTGGTGGCCGTGATGATCCGCATCGCCACCGGCTCGGCCACCGTGGCCATGACCA
CCGCCGCCGGCATCGTCGCCCCGATCGCCGCCAGCGTGCCGGGCACGCGCCCCGAACTGCTGGTGCTGACGACCGGCGCC
GGTTCGCTGATCCTGTCGCACGTCAACGACGGCGGCTTCTGGCTGGTCAAGGAGTACTTCAACATGACCGTGACCCAGAC
CTTCAAGACCTGGTCGGTCGCCGAAACGATCATTTCGGTCGTGGCGTTGCTACTGACGCTGGGACTGGCGACGGTGACCT
GA

Upstream 100 bases:

>100_bases
AGCTTTCTCAACCCGCCGCTACGCGACACAAGGCATAGCGGCTTTTTCACACGCGGAAGCGGACCGTCCGGACCGGCGGC
ACCCGCAAAAAGGAGACGAC

Downstream 100 bases:

>100_bases
GGCTTCGCGGCGGTGTTTTCTCCCCTGTTCCGCCCGACGGCGGGGGAGAAAACCCGGGGTAGCACAAAGCCCCCACCCCT
CCTACACTCCCTGTTCGATG

Product: gluconate transporter

Products: Proton [Cytoplasm]; gluconate [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 453; Mature: 452

Protein sequence:

>453_residues
MGAVTGTTLLVYALIAVIALVILIAKFKLNPFITLVVVSVALGFAVGMPMGDIIKSFEAGVGGTLGHIALVIGLGTMLGK
MMAESGGAERIALTLVDFFGEKNVHWAMVVIAFIVGLPVFFEVGFVLLVPIAFNVAKRTNTSMVLVGIPMVAGLSVVHGL
IPPHPAALLAVQAYGADMGKTIMYALIVGVPTAAIAGPLFAKLIDRHVKLPEVNPLAAQFTEEAENIKATRQLPGFGITV
FTILLPVILMLIGSWADLIATPKTFANDFLKLIGNSVMALLIAALVSFYTFGKARGFGRDAILKFTNECVAPTAIITLVV
GAGGGFGRILRDSGISTAIVDVATHANVSVLVLGWLVAVMIRIATGSATVAMTTAAGIVAPIAASVPGTRPELLVLTTGA
GSLILSHVNDGGFWLVKEYFNMTVTQTFKTWSVAETIISVVALLLTLGLATVT

Sequences:

>Translated_453_residues
MGAVTGTTLLVYALIAVIALVILIAKFKLNPFITLVVVSVALGFAVGMPMGDIIKSFEAGVGGTLGHIALVIGLGTMLGK
MMAESGGAERIALTLVDFFGEKNVHWAMVVIAFIVGLPVFFEVGFVLLVPIAFNVAKRTNTSMVLVGIPMVAGLSVVHGL
IPPHPAALLAVQAYGADMGKTIMYALIVGVPTAAIAGPLFAKLIDRHVKLPEVNPLAAQFTEEAENIKATRQLPGFGITV
FTILLPVILMLIGSWADLIATPKTFANDFLKLIGNSVMALLIAALVSFYTFGKARGFGRDAILKFTNECVAPTAIITLVV
GAGGGFGRILRDSGISTAIVDVATHANVSVLVLGWLVAVMIRIATGSATVAMTTAAGIVAPIAASVPGTRPELLVLTTGA
GSLILSHVNDGGFWLVKEYFNMTVTQTFKTWSVAETIISVVALLLTLGLATVT
>Mature_452_residues
GAVTGTTLLVYALIAVIALVILIAKFKLNPFITLVVVSVALGFAVGMPMGDIIKSFEAGVGGTLGHIALVIGLGTMLGKM
MAESGGAERIALTLVDFFGEKNVHWAMVVIAFIVGLPVFFEVGFVLLVPIAFNVAKRTNTSMVLVGIPMVAGLSVVHGLI
PPHPAALLAVQAYGADMGKTIMYALIVGVPTAAIAGPLFAKLIDRHVKLPEVNPLAAQFTEEAENIKATRQLPGFGITVF
TILLPVILMLIGSWADLIATPKTFANDFLKLIGNSVMALLIAALVSFYTFGKARGFGRDAILKFTNECVAPTAIITLVVG
AGGGFGRILRDSGISTAIVDVATHANVSVLVLGWLVAVMIRIATGSATVAMTTAAGIVAPIAASVPGTRPELLVLTTGAG
SLILSHVNDGGFWLVKEYFNMTVTQTFKTWSVAETIISVVALLLTLGLATVT

Specific function: Part Of The Gluconate Utilization System Gnt-I; High- Affinity Intake Of Gluconate. [C]

COG id: COG2610

COG function: function code GE; H+/gluconate symporter and related permeases

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the gntP permease family [H]

Homologues:

Organism=Escherichia coli, GI48994935, Length=440, Percent_Identity=46.1363636363636, Blast_Score=362, Evalue=1e-101,
Organism=Escherichia coli, GI1790716, Length=429, Percent_Identity=42.8904428904429, Blast_Score=336, Evalue=1e-93,
Organism=Escherichia coli, GI2367370, Length=428, Percent_Identity=39.9532710280374, Blast_Score=308, Evalue=4e-85,
Organism=Escherichia coli, GI1788707, Length=435, Percent_Identity=40, Blast_Score=306, Evalue=2e-84,
Organism=Escherichia coli, GI1790776, Length=433, Percent_Identity=35.1039260969977, Blast_Score=271, Evalue=5e-74,
Organism=Escherichia coli, GI48994939, Length=440, Percent_Identity=34.3181818181818, Blast_Score=244, Evalue=6e-66,
Organism=Escherichia coli, GI1789097, Length=447, Percent_Identity=33.5570469798658, Blast_Score=226, Evalue=2e-60,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003474 [H]

Pfam domain/function: PF02447 GntP_permease [H]

EC number: NA

Molecular weight: Translated: 47147; Mature: 47016

Theoretical pI: Translated: 9.34; Mature: 9.34

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
GAVTGTTLLVYALIAVIALVILIAKFKLNPFITLVVVSVALGFAVGMPMGDIIKSFEAG
CCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHCC
VGGTLGHIALVIGLGTMLGKMMAESGGAERIALTLVDFFGEKNVHWAMVVIAFIVGLPVF
CCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHH
FEVGFVLLVPIAFNVAKRTNTSMVLVGIPMVAGLSVVHGLIPPHPAALLAVQAYGADMGK
HHHHHHHHHHHHHHHHHCCCCCEEEEECHHHHHHHHHHHCCCCCHHHHHHHHHHCCCHHH
TIMYALIVGVPTAAIAGPLFAKLIDRHVKLPEVNPLAAQFTEEAENIKATRQLPGFGITV
HHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHH
FTILLPVILMLIGSWADLIATPKTFANDFLKLIGNSVMALLIAALVSFYTFGKARGFGRD
HHHHHHHHHHHHCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHH
AILKFTNECVAPTAIITLVVGAGGGFGRILRDSGISTAIVDVATHANVSVLVLGWLVAVM
HHHHHHHHHCCHHHHHHHHEECCCCHHHHHHHCCCCCHHHHHHHCCCHHHHHHHHHHHHH
IRIATGSATVAMTTAAGIVAPIAASVPGTRPELLVLTTGAGSLILSHVNDGGFWLVKEYF
HHHCCCCCEEEHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCEEEEECCCCCEEEEHHHH
NMTVTQTFKTWSVAETIISVVALLLTLGLATVT
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; gluconate [Periplasm] [C]

Specific reaction: Proton [Periplasm] + gluconate [Periplasm] = Proton [Cytoplasm] + gluconate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA