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The map label for this gene is kdgK [H]

Identifier: 94313691

GI number: 94313691

Start: 1413165

End: 1414100

Strand: Reverse

Name: kdgK [H]

Synonym: Rmet_4769

Alternate gene names: 94313691

Gene position: 1414100-1413165 (Counterclockwise)

Preceding gene: 94313692

Following gene: 94313690

Centisome position: 54.81

GC content: 64.21

Gene sequence:

>936_bases
ATGAGTATCGATATCCTTGCCTATGGCGAACCGCTGATCGAGTTCAACCAGCAGCCCGACGATCCGTCGCGTTACCTGCA
GGGCTTTGGCGGCGATACCTCCAATTTCTGCATTGCCGCCGCGCGCCAGGGCGCGACCACGGGCTATATCACCGCAGTAG
GGGCCGACAGTTTCGGTGAGCGGTTGCTGGCGTTGTGGACACGGGAACGTGTCGATACCCGACACGTGGTGGTCAATGCC
TCTGCGCCCACCGGGGTTTATTTCGTCTCCCACGACAACCACGGCCATCGCTTCGACTATCTGCGCGAGCGTTCCGCGGC
CAGCCGCTATCACCATGAGCAGTTGCCGCTGGCAACCATCGCGCAGGCGCGCTTTCTGCATCTCTCCGGTATCAGCCTGG
CAATTAGCACCAGCGCCTGTGATGCAGGACTGGCGGCGATGGAACATGCGCGCAAGGCCGGGGCGAAAGTATCGCTCGAC
ACGAATCTGCGATTGCGGCTCTGGTCGCTGGCCCGCGCGCGCGGCATCATGCGCGAGGCATTCTCCCTGACCGACATATG
CCTGCCGAGCTGGGACGACATCACGATCCTGACCGGGCTCGATGACCGCGACGCGATCGTCGACTATCTGCTGGGTTGCG
GTGTGGAACTGGTTGCGCTGAAGCTCGGAGAAGAGGGCAGTTACATCGCCACGCAGGAGTCGCGCGCGCTGGTGGCGCCG
TTCCCCGTACGTCCGGTCGATGCCACCGGCGCGGGCGACTGCTTCGGCGGCAGTTTCATCGCACGGCTGGCTGCGGACGC
TGATCCGTTCGATGCGGCTCGCTATGCCAACATTGCCGCCGCGCTGTCGACCACGGGTTATGGGGCCGTGGCGCCTATCC
CCCATGCCGAAACCGTGCGGGCCCGGCTGGAGCAGGGCGTCACAGTGATTGCCTGA

Upstream 100 bases:

>100_bases
CAGCCAGTTCCAGGTCATCGACATTGTTCAGACGTTCTTCTGACCCCGGTGTCAGTCCCTGTGGCCAGACCGAATGGAAT
GAAGAGGAGATGAAGCCGAG

Downstream 100 bases:

>100_bases
TGCATTCGGCAACAGCCTTGTCCCGTTTTACGACAATTCGGCCCCTTGCACCAACGCACCAACGCACCAACGCACCAACG
CACCAATTTATCGAAGATCC

Product: 2-Keto-3-deoxygluconate kinase

Products: NA

Alternate protein names: 2-keto-3-deoxygluconokinase; 3-deoxy-2-oxo-D-gluconate kinase; KDG kinase [H]

Number of amino acids: Translated: 311; Mature: 310

Protein sequence:

>311_residues
MSIDILAYGEPLIEFNQQPDDPSRYLQGFGGDTSNFCIAAARQGATTGYITAVGADSFGERLLALWTRERVDTRHVVVNA
SAPTGVYFVSHDNHGHRFDYLRERSAASRYHHEQLPLATIAQARFLHLSGISLAISTSACDAGLAAMEHARKAGAKVSLD
TNLRLRLWSLARARGIMREAFSLTDICLPSWDDITILTGLDDRDAIVDYLLGCGVELVALKLGEEGSYIATQESRALVAP
FPVRPVDATGAGDCFGGSFIARLAADADPFDAARYANIAAALSTTGYGAVAPIPHAETVRARLEQGVTVIA

Sequences:

>Translated_311_residues
MSIDILAYGEPLIEFNQQPDDPSRYLQGFGGDTSNFCIAAARQGATTGYITAVGADSFGERLLALWTRERVDTRHVVVNA
SAPTGVYFVSHDNHGHRFDYLRERSAASRYHHEQLPLATIAQARFLHLSGISLAISTSACDAGLAAMEHARKAGAKVSLD
TNLRLRLWSLARARGIMREAFSLTDICLPSWDDITILTGLDDRDAIVDYLLGCGVELVALKLGEEGSYIATQESRALVAP
FPVRPVDATGAGDCFGGSFIARLAADADPFDAARYANIAAALSTTGYGAVAPIPHAETVRARLEQGVTVIA
>Mature_310_residues
SIDILAYGEPLIEFNQQPDDPSRYLQGFGGDTSNFCIAAARQGATTGYITAVGADSFGERLLALWTRERVDTRHVVVNAS
APTGVYFVSHDNHGHRFDYLRERSAASRYHHEQLPLATIAQARFLHLSGISLAISTSACDAGLAAMEHARKAGAKVSLDT
NLRLRLWSLARARGIMREAFSLTDICLPSWDDITILTGLDDRDAIVDYLLGCGVELVALKLGEEGSYIATQESRALVAPF
PVRPVDATGAGDCFGGSFIARLAADADPFDAARYANIAAALSTTGYGAVAPIPHAETVRARLEQGVTVIA

Specific function: Unknown

COG id: COG0524

COG function: function code G; Sugar kinases, ribokinase family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the carbohydrate kinase pfkB family [H]

Homologues:

Organism=Homo sapiens, GI11545855, Length=291, Percent_Identity=27.4914089347079, Blast_Score=73, Evalue=3e-13,
Organism=Escherichia coli, GI87082281, Length=306, Percent_Identity=31.0457516339869, Blast_Score=124, Evalue=1e-29,
Organism=Escherichia coli, GI87081971, Length=315, Percent_Identity=25.0793650793651, Blast_Score=92, Evalue=4e-20,
Organism=Escherichia coli, GI1790193, Length=288, Percent_Identity=27.0833333333333, Blast_Score=69, Evalue=5e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011611
- InterPro:   IPR002173 [H]

Pfam domain/function: PF00294 PfkB [H]

EC number: =2.7.1.45 [H]

Molecular weight: Translated: 33353; Mature: 33222

Theoretical pI: Translated: 5.56; Mature: 5.56

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSIDILAYGEPLIEFNQQPDDPSRYLQGFGGDTSNFCIAAARQGATTGYITAVGADSFGE
CEEEEEECCCHHHCCCCCCCCHHHHHHCCCCCCCCEEEEEECCCCCCEEEEEECCCHHHH
RLLALWTRERVDTRHVVVNASAPTGVYFVSHDNHGHRFDYLRERSAASRYHHEQLPLATI
HHHHHHHHHCCCCEEEEEECCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHCCCHHHH
AQARFLHLSGISLAISTSACDAGLAAMEHARKAGAKVSLDTNLRLRLWSLARARGIMREA
HHHHEEEECCCEEEEECCCCHHHHHHHHHHHHCCCEEEECCCCEEEHHHHHHHHHHHHHH
FSLTDICLPSWDDITILTGLDDRDAIVDYLLGCGVELVALKLGEEGSYIATQESRALVAP
HHHHHHCCCCCCCEEEEECCCCHHHHHHHHHHCCCEEEEEEECCCCCEEEECCCCEEECC
FPVRPVDATGAGDCFGGSFIARLAADADPFDAARYANIAAALSTTGYGAVAPIPHAETVR
CCCCCCCCCCCCCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCHHHHH
ARLEQGVTVIA
HHHHCCCEEEC
>Mature Secondary Structure 
SIDILAYGEPLIEFNQQPDDPSRYLQGFGGDTSNFCIAAARQGATTGYITAVGADSFGE
EEEEEECCCHHHCCCCCCCCHHHHHHCCCCCCCCEEEEEECCCCCCEEEEEECCCHHHH
RLLALWTRERVDTRHVVVNASAPTGVYFVSHDNHGHRFDYLRERSAASRYHHEQLPLATI
HHHHHHHHHCCCCEEEEEECCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHCCCHHHH
AQARFLHLSGISLAISTSACDAGLAAMEHARKAGAKVSLDTNLRLRLWSLARARGIMREA
HHHHEEEECCCEEEEECCCCHHHHHHHHHHHHCCCEEEECCCCEEEHHHHHHHHHHHHHH
FSLTDICLPSWDDITILTGLDDRDAIVDYLLGCGVELVALKLGEEGSYIATQESRALVAP
HHHHHHCCCCCCCEEEEECCCCHHHHHHHHHHCCCEEEEEEECCCCCEEEECCCCEEECC
FPVRPVDATGAGDCFGGSFIARLAADADPFDAARYANIAAALSTTGYGAVAPIPHAETVR
CCCCCCCCCCCCCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCHHHHH
ARLEQGVTVIA
HHHHCCCEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8157608 [H]