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The map label for this gene is ribB [H]

Identifier: 94313680

GI number: 94313680

Start: 1404435

End: 1405121

Strand: Reverse

Name: ribB [H]

Synonym: Rmet_4758

Alternate gene names: 94313680

Gene position: 1405121-1404435 (Counterclockwise)

Preceding gene: 94313682

Following gene: 94313679

Centisome position: 54.46

GC content: 64.63

Gene sequence:

>687_bases
ATGCTGACCCTTACCAAATCCACCAGCCTTCCTGATTCCACCGCCGCACTGGCGCCATCCGATGCCGACGCGCGTCCACT
GGCCGAGCGCATCGCGCAGGCCCTCGATGCGATGCGCGATGGCCGTCCGGTCGTACTGCTCGACGATGACGACCGCGAAA
ACGAGGCAGACCTGATTCTTGCAGCGGAGCGGCTGACGAACTCGAACATGGCCATGATGATCCGCGAATGCAGCGGCATC
GTCTGCCTGTGCCTCACGCCGGAGAAGGTGCGGCAACTCGGCCTGCGGCCGATGGTCGAGAACAATCGCAGCCAGTACGG
CACTGCGTTCACGGTATCGATCGAGGCGCGTGAAGGCGTGACCACCGGTGTCAGCGCGGCGGACCGGATCACGACCATTC
GCGCAGCCATCGCCGATGAGGCGGGCCTTGATGCCGTGGTGAGCCCCGGACACGTGTTTCCTCTGGTAGCAGTGGAAGGG
GGTGTGCTGGCGCGTCGCGGGCATACCGAGGGCTCGGTCGAGCTTGCGCGCATGGCGGGACTGTCGCCGGCCGCGGTGTT
GTGCGAGTTGATGAATCCCGATGGCACGATGGCACGCAGGCCCGAAGCGCTGGCGTTTGCCGAGATGTATCAGTTGCCAG
TACTGACGATCGCCGATCTGGTGGCGTGGCGGGAAATTAACGCCTGA

Upstream 100 bases:

>100_bases
CGCGATGTCGTCCATTGCGTGCTGTCGGGGTGTCTTTGCCGTTCTCGCTGATCATCCCCTGAAACGCCCATCCATGGAAA
TCCACGCACGGAGCGTTTCA

Downstream 100 bases:

>100_bases
CCAGCCGCAAACAAATGACGCGGCGGGGATCTCAAAACGATGCAGATCGATCAAGATCATCGTCGCGCGCGAACGCTGTG
CGAAAATGCGGGGACTTTTT

Product: 3,4-dihydroxy-2-butanone 4-phosphate synthase

Products: NA

Alternate protein names: DHBP synthase [H]

Number of amino acids: Translated: 228; Mature: 228

Protein sequence:

>228_residues
MLTLTKSTSLPDSTAALAPSDADARPLAERIAQALDAMRDGRPVVLLDDDDRENEADLILAAERLTNSNMAMMIRECSGI
VCLCLTPEKVRQLGLRPMVENNRSQYGTAFTVSIEAREGVTTGVSAADRITTIRAAIADEAGLDAVVSPGHVFPLVAVEG
GVLARRGHTEGSVELARMAGLSPAAVLCELMNPDGTMARRPEALAFAEMYQLPVLTIADLVAWREINA

Sequences:

>Translated_228_residues
MLTLTKSTSLPDSTAALAPSDADARPLAERIAQALDAMRDGRPVVLLDDDDRENEADLILAAERLTNSNMAMMIRECSGI
VCLCLTPEKVRQLGLRPMVENNRSQYGTAFTVSIEAREGVTTGVSAADRITTIRAAIADEAGLDAVVSPGHVFPLVAVEG
GVLARRGHTEGSVELARMAGLSPAAVLCELMNPDGTMARRPEALAFAEMYQLPVLTIADLVAWREINA
>Mature_228_residues
MLTLTKSTSLPDSTAALAPSDADARPLAERIAQALDAMRDGRPVVLLDDDDRENEADLILAAERLTNSNMAMMIRECSGI
VCLCLTPEKVRQLGLRPMVENNRSQYGTAFTVSIEAREGVTTGVSAADRITTIRAAIADEAGLDAVVSPGHVFPLVAVEG
GVLARRGHTEGSVELARMAGLSPAAVLCELMNPDGTMARRPEALAFAEMYQLPVLTIADLVAWREINA

Specific function: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate [H]

COG id: COG0108

COG function: function code H; 3,4-dihydroxy-2-butanone 4-phosphate synthase

Gene ontology:

Cell location: Membrane-Associated [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DHBP synthase family [H]

Homologues:

Organism=Escherichia coli, GI1789420, Length=197, Percent_Identity=60.4060913705584, Blast_Score=239, Evalue=1e-64,
Organism=Saccharomyces cerevisiae, GI6320695, Length=202, Percent_Identity=39.6039603960396, Blast_Score=155, Evalue=7e-39,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017945
- InterPro:   IPR000422 [H]

Pfam domain/function: PF00926 DHBP_synthase [H]

EC number: =4.1.99.12 [H]

Molecular weight: Translated: 24299; Mature: 24299

Theoretical pI: Translated: 4.43; Mature: 4.43

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
4.4 %Met     (Translated Protein)
6.1 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
4.4 %Met     (Mature Protein)
6.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLTLTKSTSLPDSTAALAPSDADARPLAERIAQALDAMRDGRPVVLLDDDDRENEADLIL
CEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCEEE
AAERLTNSNMAMMIRECSGIVCLCLTPEKVRQLGLRPMVENNRSQYGTAFTVSIEAREGV
EEHHHCCCCHHEEEECCCCEEEEEECHHHHHHCCCCCCCCCCCCCCCEEEEEEEECCCCC
TTGVSAADRITTIRAAIADEAGLDAVVSPGHVFPLVAVEGGVLARRGHTEGSVELARMAG
CCCCCHHHHHHHHHHHHHCCCCCCEEECCCCEEEEEEECCCEEEECCCCCCCCHHHHHCC
LSPAAVLCELMNPDGTMARRPEALAFAEMYQLPVLTIADLVAWREINA
CCHHHHHHHHCCCCCCCCCCCHHHHHHHHHHCHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MLTLTKSTSLPDSTAALAPSDADARPLAERIAQALDAMRDGRPVVLLDDDDRENEADLIL
CEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCEEE
AAERLTNSNMAMMIRECSGIVCLCLTPEKVRQLGLRPMVENNRSQYGTAFTVSIEAREGV
EEHHHCCCCHHEEEECCCCEEEEEECHHHHHHCCCCCCCCCCCCCCCEEEEEEEECCCCC
TTGVSAADRITTIRAAIADEAGLDAVVSPGHVFPLVAVEGGVLARRGHTEGSVELARMAG
CCCCCHHHHHHHHHHHHHCCCCCCEEECCCCEEEEEEECCCEEEECCCCCCCCHHHHHCC
LSPAAVLCELMNPDGTMARRPEALAFAEMYQLPVLTIADLVAWREINA
CCHHHHHHHHCCCCCCCCCCCHHHHHHHHHHCHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA