Click here to switch to the map view.

The map label for this gene is regX3 [H]

Identifier: 94313647

GI number: 94313647

Start: 1367948

End: 1368733

Strand: Direct

Name: regX3 [H]

Synonym: Rmet_4725

Alternate gene names: 94313647

Gene position: 1367948-1368733 (Clockwise)

Preceding gene: 94313643

Following gene: 94313649

Centisome position: 53.02

GC content: 65.14

Gene sequence:

>786_bases
ATGAATGCCCGAACGAACATCGCGCTGCTTGCAAACAGCTCGTCACCCCTGCATCCGCTGCAGGAACTCCTTGCCGTCGC
CGGCTACCAATGCAACGTCTTTCACGCCGGGCGTGACCTGATTCAAGGGCTCGGCCATGACACCTACGAGATGCTCCTGA
TCGACCGTGAGCTGGCCGACATCTCCGCCATCGACGTGATTCGCACCGTCCGGGCGGTGCGCAACCGCGACGTGCCAATC
GTGATCTTTGCCAGCGAGAACAATGACGACGACCTCGTCGAGGCCCTTGATGCCGGCGCCGACGACTACGTGCTTCGCCC
GCTGGCCGCGCGCGTGCTGCTGGCCCGCATCGCCGCATTGCGCCGGCGCATGAGCGGCACGCGCTTGCGCGGAGCCATGC
CGTTGCGCGCCGGGCCATACGAGCTGAGCAACCCCGGTCGCTACGCCACGCTCAATGGCGGCCGGATTCCGATGACGCCC
AAGGAGTTCGACCTGGCCATGCTGATGTTCGCCAACGCGGGCCGCATTCTGGCCAGCCGCCGCATCGAGCACACAATCTG
GGGACATGACTTGCCGCCCTACTCCCGCGCGCTGGCCGGACTGGTATCGCGAATGCGTCGTACCCTGAACCTGTGCGCGG
AGAACGGCGTCACGGTCAGCGTCGTCTATGCCCAGGGGTATCGGCTGGACATCCTCGATCAAGCTGCGCGCCACGAATTG
TCCGCTGCCGCTCGCGCGGCCTCCGCGTCATCGACCCCTGCGCGGATGTTCAAATTGCTTTCGTAA

Upstream 100 bases:

>100_bases
TCCGACGTCAACGCCATCCATTTAAGGAAACACCGATTGTTCGCCCTGCCAACGCTGGCTACGCTGCAACGCGTTTACTT
CGCTTTCCAGAGAATGTCGC

Downstream 100 bases:

>100_bases
GACCGCCTGAAAATCCAGATCTAGATATCGAGCGCGCCGCGCGCAGCCAGTTCGGCGATATCGATCCGCGCAACGCCTGA
TGGCGCGCGCTTGGCGCTGC

Product: putative winged helix family two component transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 261; Mature: 261

Protein sequence:

>261_residues
MNARTNIALLANSSSPLHPLQELLAVAGYQCNVFHAGRDLIQGLGHDTYEMLLIDRELADISAIDVIRTVRAVRNRDVPI
VIFASENNDDDLVEALDAGADDYVLRPLAARVLLARIAALRRRMSGTRLRGAMPLRAGPYELSNPGRYATLNGGRIPMTP
KEFDLAMLMFANAGRILASRRIEHTIWGHDLPPYSRALAGLVSRMRRTLNLCAENGVTVSVVYAQGYRLDILDQAARHEL
SAAARAASASSTPARMFKLLS

Sequences:

>Translated_261_residues
MNARTNIALLANSSSPLHPLQELLAVAGYQCNVFHAGRDLIQGLGHDTYEMLLIDRELADISAIDVIRTVRAVRNRDVPI
VIFASENNDDDLVEALDAGADDYVLRPLAARVLLARIAALRRRMSGTRLRGAMPLRAGPYELSNPGRYATLNGGRIPMTP
KEFDLAMLMFANAGRILASRRIEHTIWGHDLPPYSRALAGLVSRMRRTLNLCAENGVTVSVVYAQGYRLDILDQAARHEL
SAAARAASASSTPARMFKLLS
>Mature_261_residues
MNARTNIALLANSSSPLHPLQELLAVAGYQCNVFHAGRDLIQGLGHDTYEMLLIDRELADISAIDVIRTVRAVRNRDVPI
VIFASENNDDDLVEALDAGADDYVLRPLAARVLLARIAALRRRMSGTRLRGAMPLRAGPYELSNPGRYATLNGGRIPMTP
KEFDLAMLMFANAGRILASRRIEHTIWGHDLPPYSRALAGLVSRMRRTLNLCAENGVTVSVVYAQGYRLDILDQAARHEL
SAAARAASASSTPARMFKLLS

Specific function: Part of the two-component regulatory system senX3/regX3. Once phosphorylated by senX3, activates the expression of several operons/genes involved in phosphate assimilation and metabolism, such as pstSCAB, phnDCE, and phoA [H]

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1789402, Length=206, Percent_Identity=31.5533980582524, Blast_Score=88, Evalue=6e-19,
Organism=Escherichia coli, GI1786784, Length=190, Percent_Identity=27.3684210526316, Blast_Score=76, Evalue=2e-15,
Organism=Escherichia coli, GI1786599, Length=183, Percent_Identity=26.775956284153, Blast_Score=75, Evalue=3e-15,
Organism=Escherichia coli, GI1790860, Length=227, Percent_Identity=22.4669603524229, Blast_Score=72, Evalue=4e-14,
Organism=Escherichia coli, GI87082012, Length=201, Percent_Identity=24.3781094527363, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI2367329, Length=217, Percent_Identity=25.8064516129032, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1786911, Length=161, Percent_Identity=27.3291925465839, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1790552, Length=179, Percent_Identity=27.3743016759777, Blast_Score=69, Evalue=4e-13,
Organism=Escherichia coli, GI1787375, Length=214, Percent_Identity=23.8317757009346, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1788394, Length=216, Percent_Identity=23.1481481481481, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1789809, Length=212, Percent_Identity=22.1698113207547, Blast_Score=62, Evalue=4e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 28599; Mature: 28599

Theoretical pI: Translated: 9.64; Mature: 9.64

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS00290 IG_MHC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNARTNIALLANSSSPLHPLQELLAVAGYQCNVFHAGRDLIQGLGHDTYEMLLIDRELAD
CCCCCEEEEEECCCCCHHHHHHHHHHCCCCEEEEHHHHHHHHHCCCCCEEEEEEHHHHHH
ISAIDVIRTVRAVRNRDVPIVIFASENNDDDLVEALDAGADDYVLRPLAARVLLARIAAL
HHHHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHH
RRRMSGTRLRGAMPLRAGPYELSNPGRYATLNGGRIPMTPKEFDLAMLMFANAGRILASR
HHHHCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCCCCCCHHHHHHHHHHCCCHHHHHH
RIEHTIWGHDLPPYSRALAGLVSRMRRTLNLCAENGVTVSVVYAQGYRLDILDQAARHEL
HHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCEEHHHHHHHHHHH
SAAARAASASSTPARMFKLLS
HHHHHHCCCCCCHHHHHHHCC
>Mature Secondary Structure
MNARTNIALLANSSSPLHPLQELLAVAGYQCNVFHAGRDLIQGLGHDTYEMLLIDRELAD
CCCCCEEEEEECCCCCHHHHHHHHHHCCCCEEEEHHHHHHHHHCCCCCEEEEEEHHHHHH
ISAIDVIRTVRAVRNRDVPIVIFASENNDDDLVEALDAGADDYVLRPLAARVLLARIAAL
HHHHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHH
RRRMSGTRLRGAMPLRAGPYELSNPGRYATLNGGRIPMTPKEFDLAMLMFANAGRILASR
HHHHCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCCCCCCHHHHHHHHHHCCCHHHHHH
RIEHTIWGHDLPPYSRALAGLVSRMRRTLNLCAENGVTVSVVYAQGYRLDILDQAARHEL
HHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCEEHHHHHHHHHHH
SAAARAASASSTPARMFKLLS
HHHHHHCCCCCCHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA