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The map label for this gene is rcsC [H]

Identifier: 94313527

GI number: 94313527

Start: 1226504

End: 1230433

Strand: Reverse

Name: rcsC [H]

Synonym: Rmet_4605

Alternate gene names: 94313527

Gene position: 1230433-1226504 (Counterclockwise)

Preceding gene: 94313529

Following gene: 94313521

Centisome position: 47.69

GC content: 63.28

Gene sequence:

>3930_bases
ATGCAGCCCGCCATGGCGCTGCCGGCGAAACTGACCGTCGGCATGCTCGACAACGGCTGGCCTCCGTTCACGATGCTCAA
TGCCGGGCGGGCCGAAGGCATCGGCATGGATTTCCTTCATGAGGCTCTGCGCGGACACCAGATCACGTACAGCGTGAAGG
GGTATCCCGACATGACGGCCCTTCTGGCGGCGTTGTGCAAGGGCGATGTGGACGTGGTGCTCAATGTTGCCATCACGCCG
GCACGACGTCGGTGCCTCTCCTTCTCCGAGCCATACTTTGATGGTGATGCCGTGGTGGTCGGTCGTCCGTCCGCCGCGTT
GGAAGAAGACCTGCTTGCGTCCATGCAAACCGGCCGCTTCGCGATCGAGCCCGGTTATTACATGGAGGGCATTCTGCGCC
AGCGTTATCCGAAGGCGCGCATGGTGCCCATCAAGGACACGACCGATGGATTGCGCGCCATCGTGAACGGGCGGGCCGAC
TACTACGCCACCGTGCAGCCAGTGGCCGAGTATGCAATGGTTTCACCTGAGTTTGCGGGACTGAAGGTCCTCTCGCGCTA
CCGGGAGCCAACAGGAGCCATTCACTTTGCGTTTCGATCCAACGCGACGGAACTGCGTGACGCGACCGATGCCGGCCTGG
CGGCGATTGATCCAGCTCGCCGCGCTGCCTTGCTGGCACACTGGATAACCTCGCAGGTGGCCTCGCCCGACAAGCCCCAG
AAATTCTTCCTGACCGACGAGGAGCGTGCGTTCCTGAAGTCGTTGCCAACCTTGACGGTTGGTGTCGACGCGGGGCTCGC
GCCCTACACGTACCTGGACGAGAGTGGCCGCGCCAGCGGCATAGCGATTGACTATCTGAGTTACCTTGGCGAGACCCTGG
GCGTCCGCTTCCGACGCCAGCCGACGACTGACATCCAGCAGACCGTCGAGGCGCTGCATCAGGGCAAGATCGATCTGATG
GCCGTAGCGGTGCCAGAGGACCCCACGCTGCGCGGCTTGCCGGTATCCCGTCCGTACTCGACGTTTCCAGTGGTGGTGGC
GGGCAGAAACTCGGCCTTGCCGCTCGCACACCTGCGCGACCTCACCGGAAAGCGAGTTGTCGTCACCGACTCTGGCGGGG
TTGGCGATTTCACCCGGCACGAGGTACCGGGCGTGAAGCTGGTGATCGCCCCGAATGTCCACGCCGGACTCGACATGGTG
GCGCAGGGGAAAGCCGATGCTTATGTCGACGATATCGTCTCGACCGATATCGAACTGCGACGCAATTTTGCCGGCAAGCT
ACGCGTGATCGGTTCGGGCGAGCACATGCTCAACAGCGGCTTTGCGGTCAACCCCGCGCTAGCCGGGCGACTGCTGCCAT
TGATCAATCGCGCACTCTCCGTGCTACCGGAGGACCGCCGGCTGGATATCCAGAATCGCTACGCCGGCACCAGCTATGTG
CTGGAAACGTCGTGGCTGAATGCGCTCTGGCGGGCGAGTCCAATCCTGATCGGGATGATGGTCATCCTCCTGATCCTGCT
TCGTTCCCAGCGCCTGTACCGCAAGGAGGCTTCCATTCGTCGCGAGGCCGAACGGGAGCTTTCGACCCAGTTGCGCTTCC
AGTCGACGCTGATGGATGCCATCCCCCTGCCCATTGTGGTCAGTAACAAGGACGGCCGGTATCTGCGGTTGAACGCATTC
TCCGAGTGGATCACGGGGCGGTCATGGGCCGACATCGTAGGTCACACCACCACGGAAGTACATTTCTGGGGCGAGGCGAA
CAGCGCGCGGGTGGAGGAGGCGAGCCAGCGGGCCATCGACACAGGCAGGCTGGTGCAACTCCAGTTGCAACTGCAGGACA
AGGAGGGCGTGGAGCGGCATTTCCTTCTCTATATCAAGCCCTTTGTCGGCGAAAACAATGTCGAGGGACTGATCAACACC
GGCGTGGATGTGACGGAAATCCGCCAGGCGGAGCTCGAGGCGCGCGAGGCACAGGGCCGTCTGGCCGACGTCACGCGCTA
CCTGCCGATCATGGTGTTCCAGGCACGCCAGTCGGGCCACCTAGGCCGGGGACCGATATGGGTGAGTGGCAATACCACGG
ATCTGTTTGGCGTCGACGCCGAAACCCTGGCGGTCAATCCCCCCACGATCGAAGCTTGTGTGCATCCCGATGACCGGATG
TCCCTGCGTCGCGCCATCGCCAGGGCGCGGCGGGAGCTTCAGGTTCTGAACCACGAAGTGCGCCTGCGCAAGCTGGAAGG
GTTTCGCTGGACGCGTTTGCAGGCCGTGCCCCGTATCGAGATCGACGGCAGCGTGCTCTGGAATGGCTATTGGCGTGACA
CCCAGGCCGAGCATGAACGCGCGGCTGCGCTGGCCAGCGCCAAGGAATCCGCGGAGGCGGCATCCCGTGCCAAGGATAGT
TTCCTGGCCATGATGAGCCATGAGATTCGCACGCCGATGAACGGCGTACTGGGGCTTGCGGAACTGCTTTCCCATACGTC
CCTGACGCCGGAACAATCCGCCACGGTCGGCATGATGGGGGATTCGGCGAGCGCGTTGCTCCAGATTCTCGACGATATCC
TGGACTACTCGAAGATTGAAGCCGGCCGCATTGACATTGAATCCCGGCCATTGGATATCCGCGAGCTTTGCGATTGCACC
ATCGGTGTGCTGGCGACACGCGCGCATGAGAAAGGCCTGCATCTGCGGCTGCATGTGGGGGCGGATGTTGCCGCCGTGGT
ACTAGGCGACAGCGTGCGCCTGCGCCAGGTCCTGTTTAACCTGCTCAGCAACGCCATCAAGTTCACCGAAAGCGGCATGG
TGTCGGTGTCCGCCGAGGTGGTACAGGAAACGGAGACCGCGCAAACCCTCCGGTGGCGCGTGACCGATACCGGTATCGGC
ATCGAGCCGCAGAACCAGAGCCGGCTGTTCGATCCTTTCGTGCAGGCCGACACGTCGACCACGCGCCGTTTCGGCGGCAC
GGGCCTTGGCCTGGCAATCTGCCGGCGTCTGGTGCAGTTGATGGGTGGGCGCATCACACTGAAGAGCGAGCCCGGCATCG
GCACCCAGGTCGAGGTCGAGTTGAGCCTCCCGGTCAAGGAAAGACGCTATTCAAAGCCGCCGCTGGCGGGCATCCAGTTC
GGGGTCCGCTTGCGGGATTGCGCGGTGGGCCAAGCGCTGACGGACTTCCTGTCTGCCGCTGGCGCGACCAACTCTGCAAG
CCAGGACGAGCGTGACAAGCCGCAGATGCTGTTCCTCAACGACGGCGAGTATGCGCCGCCGTCGCCGGTCGGGCAGGCCA
GCCCCATCGTCGTGCATGTCACGGAAAAACCCAAACTGGCGGGCTACCGGCTGACAGAATCCGATGTCCGCCTGAGCAGC
AATCCCGTGAGCTGGCGCGCGATCAACGCGGTGACGGTCGCCGCCATGCAGGGCCGGGCGCACACTGTCGCTACCCATGC
GCAGGCCAAGCCGAAGCCTGCTGCGCACGCAGTGACGCGAGAACAGGCGCTGGCATCCGGCAGGTTGATCCTGGTGGCGG
AAGACCACGAAACCAATCGTATCCTGCTGCAGCATCAGCTAAAGCTGCTCGGTTATGCCTGCGATGCCGTGGTCGACGGG
CAGCAGGCACTCGAGGCCGCCGAGAAGACGGCCTACGCGATGCTGATCACGGATTGCCACATGCCGAACGTCAACGGCTA
TGAACTGGCAAGACAGCTTCGCGCCCGCGAAGCCGAAGCCAAAACGGAAGCCGGAACGGACGCCCATCGCCTCCCGATCG
TCGCAATCACGGCCAGCACCGAAGCCGAAGAAGTCCAGCGCTGCAGAGAGGCCGGGATCGACGAATGCATGTTCAAGCCG
ACACAGCTCAATGCCTTGCGCGCGTGTCTCCAGAGATGGAACCCGGACAATCAGGACGCCGACGGGCGCAAGGGGTCCGG
CAAGGCCTGA

Upstream 100 bases:

>100_bases
TCCTCTTCCTGGGCATGACCTCATGAAAGAGACACTTCGCCACGCCGCCTCCCAATGCCGGCGCTGGACGCTGTCCGTCC
TGATCCTCGGTCTGAGCCTG

Downstream 100 bases:

>100_bases
AAGTAGCTGGGTTACGGCGGCTGCATGTCGCTCCCCGGAGGCGCCGGTGAACCGGCGCGGCAGCGCCACGATCGATCAAC
GCCACGCGGTCTACTGCCTC

Product: histidine protein kinase

Products: NA

Alternate protein names: Capsular synthesis regulator component C [H]

Number of amino acids: Translated: 1309; Mature: 1309

Protein sequence:

>1309_residues
MQPAMALPAKLTVGMLDNGWPPFTMLNAGRAEGIGMDFLHEALRGHQITYSVKGYPDMTALLAALCKGDVDVVLNVAITP
ARRRCLSFSEPYFDGDAVVVGRPSAALEEDLLASMQTGRFAIEPGYYMEGILRQRYPKARMVPIKDTTDGLRAIVNGRAD
YYATVQPVAEYAMVSPEFAGLKVLSRYREPTGAIHFAFRSNATELRDATDAGLAAIDPARRAALLAHWITSQVASPDKPQ
KFFLTDEERAFLKSLPTLTVGVDAGLAPYTYLDESGRASGIAIDYLSYLGETLGVRFRRQPTTDIQQTVEALHQGKIDLM
AVAVPEDPTLRGLPVSRPYSTFPVVVAGRNSALPLAHLRDLTGKRVVVTDSGGVGDFTRHEVPGVKLVIAPNVHAGLDMV
AQGKADAYVDDIVSTDIELRRNFAGKLRVIGSGEHMLNSGFAVNPALAGRLLPLINRALSVLPEDRRLDIQNRYAGTSYV
LETSWLNALWRASPILIGMMVILLILLRSQRLYRKEASIRREAERELSTQLRFQSTLMDAIPLPIVVSNKDGRYLRLNAF
SEWITGRSWADIVGHTTTEVHFWGEANSARVEEASQRAIDTGRLVQLQLQLQDKEGVERHFLLYIKPFVGENNVEGLINT
GVDVTEIRQAELEAREAQGRLADVTRYLPIMVFQARQSGHLGRGPIWVSGNTTDLFGVDAETLAVNPPTIEACVHPDDRM
SLRRAIARARRELQVLNHEVRLRKLEGFRWTRLQAVPRIEIDGSVLWNGYWRDTQAEHERAAALASAKESAEAASRAKDS
FLAMMSHEIRTPMNGVLGLAELLSHTSLTPEQSATVGMMGDSASALLQILDDILDYSKIEAGRIDIESRPLDIRELCDCT
IGVLATRAHEKGLHLRLHVGADVAAVVLGDSVRLRQVLFNLLSNAIKFTESGMVSVSAEVVQETETAQTLRWRVTDTGIG
IEPQNQSRLFDPFVQADTSTTRRFGGTGLGLAICRRLVQLMGGRITLKSEPGIGTQVEVELSLPVKERRYSKPPLAGIQF
GVRLRDCAVGQALTDFLSAAGATNSASQDERDKPQMLFLNDGEYAPPSPVGQASPIVVHVTEKPKLAGYRLTESDVRLSS
NPVSWRAINAVTVAAMQGRAHTVATHAQAKPKPAAHAVTREQALASGRLILVAEDHETNRILLQHQLKLLGYACDAVVDG
QQALEAAEKTAYAMLITDCHMPNVNGYELARQLRAREAEAKTEAGTDAHRLPIVAITASTEAEEVQRCREAGIDECMFKP
TQLNALRACLQRWNPDNQDADGRKGSGKA

Sequences:

>Translated_1309_residues
MQPAMALPAKLTVGMLDNGWPPFTMLNAGRAEGIGMDFLHEALRGHQITYSVKGYPDMTALLAALCKGDVDVVLNVAITP
ARRRCLSFSEPYFDGDAVVVGRPSAALEEDLLASMQTGRFAIEPGYYMEGILRQRYPKARMVPIKDTTDGLRAIVNGRAD
YYATVQPVAEYAMVSPEFAGLKVLSRYREPTGAIHFAFRSNATELRDATDAGLAAIDPARRAALLAHWITSQVASPDKPQ
KFFLTDEERAFLKSLPTLTVGVDAGLAPYTYLDESGRASGIAIDYLSYLGETLGVRFRRQPTTDIQQTVEALHQGKIDLM
AVAVPEDPTLRGLPVSRPYSTFPVVVAGRNSALPLAHLRDLTGKRVVVTDSGGVGDFTRHEVPGVKLVIAPNVHAGLDMV
AQGKADAYVDDIVSTDIELRRNFAGKLRVIGSGEHMLNSGFAVNPALAGRLLPLINRALSVLPEDRRLDIQNRYAGTSYV
LETSWLNALWRASPILIGMMVILLILLRSQRLYRKEASIRREAERELSTQLRFQSTLMDAIPLPIVVSNKDGRYLRLNAF
SEWITGRSWADIVGHTTTEVHFWGEANSARVEEASQRAIDTGRLVQLQLQLQDKEGVERHFLLYIKPFVGENNVEGLINT
GVDVTEIRQAELEAREAQGRLADVTRYLPIMVFQARQSGHLGRGPIWVSGNTTDLFGVDAETLAVNPPTIEACVHPDDRM
SLRRAIARARRELQVLNHEVRLRKLEGFRWTRLQAVPRIEIDGSVLWNGYWRDTQAEHERAAALASAKESAEAASRAKDS
FLAMMSHEIRTPMNGVLGLAELLSHTSLTPEQSATVGMMGDSASALLQILDDILDYSKIEAGRIDIESRPLDIRELCDCT
IGVLATRAHEKGLHLRLHVGADVAAVVLGDSVRLRQVLFNLLSNAIKFTESGMVSVSAEVVQETETAQTLRWRVTDTGIG
IEPQNQSRLFDPFVQADTSTTRRFGGTGLGLAICRRLVQLMGGRITLKSEPGIGTQVEVELSLPVKERRYSKPPLAGIQF
GVRLRDCAVGQALTDFLSAAGATNSASQDERDKPQMLFLNDGEYAPPSPVGQASPIVVHVTEKPKLAGYRLTESDVRLSS
NPVSWRAINAVTVAAMQGRAHTVATHAQAKPKPAAHAVTREQALASGRLILVAEDHETNRILLQHQLKLLGYACDAVVDG
QQALEAAEKTAYAMLITDCHMPNVNGYELARQLRAREAEAKTEAGTDAHRLPIVAITASTEAEEVQRCREAGIDECMFKP
TQLNALRACLQRWNPDNQDADGRKGSGKA
>Mature_1309_residues
MQPAMALPAKLTVGMLDNGWPPFTMLNAGRAEGIGMDFLHEALRGHQITYSVKGYPDMTALLAALCKGDVDVVLNVAITP
ARRRCLSFSEPYFDGDAVVVGRPSAALEEDLLASMQTGRFAIEPGYYMEGILRQRYPKARMVPIKDTTDGLRAIVNGRAD
YYATVQPVAEYAMVSPEFAGLKVLSRYREPTGAIHFAFRSNATELRDATDAGLAAIDPARRAALLAHWITSQVASPDKPQ
KFFLTDEERAFLKSLPTLTVGVDAGLAPYTYLDESGRASGIAIDYLSYLGETLGVRFRRQPTTDIQQTVEALHQGKIDLM
AVAVPEDPTLRGLPVSRPYSTFPVVVAGRNSALPLAHLRDLTGKRVVVTDSGGVGDFTRHEVPGVKLVIAPNVHAGLDMV
AQGKADAYVDDIVSTDIELRRNFAGKLRVIGSGEHMLNSGFAVNPALAGRLLPLINRALSVLPEDRRLDIQNRYAGTSYV
LETSWLNALWRASPILIGMMVILLILLRSQRLYRKEASIRREAERELSTQLRFQSTLMDAIPLPIVVSNKDGRYLRLNAF
SEWITGRSWADIVGHTTTEVHFWGEANSARVEEASQRAIDTGRLVQLQLQLQDKEGVERHFLLYIKPFVGENNVEGLINT
GVDVTEIRQAELEAREAQGRLADVTRYLPIMVFQARQSGHLGRGPIWVSGNTTDLFGVDAETLAVNPPTIEACVHPDDRM
SLRRAIARARRELQVLNHEVRLRKLEGFRWTRLQAVPRIEIDGSVLWNGYWRDTQAEHERAAALASAKESAEAASRAKDS
FLAMMSHEIRTPMNGVLGLAELLSHTSLTPEQSATVGMMGDSASALLQILDDILDYSKIEAGRIDIESRPLDIRELCDCT
IGVLATRAHEKGLHLRLHVGADVAAVVLGDSVRLRQVLFNLLSNAIKFTESGMVSVSAEVVQETETAQTLRWRVTDTGIG
IEPQNQSRLFDPFVQADTSTTRRFGGTGLGLAICRRLVQLMGGRITLKSEPGIGTQVEVELSLPVKERRYSKPPLAGIQF
GVRLRDCAVGQALTDFLSAAGATNSASQDERDKPQMLFLNDGEYAPPSPVGQASPIVVHVTEKPKLAGYRLTESDVRLSS
NPVSWRAINAVTVAAMQGRAHTVATHAQAKPKPAAHAVTREQALASGRLILVAEDHETNRILLQHQLKLLGYACDAVVDG
QQALEAAEKTAYAMLITDCHMPNVNGYELARQLRAREAEAKTEAGTDAHRLPIVAITASTEAEEVQRCREAGIDECMFKP
TQLNALRACLQRWNPDNQDADGRKGSGKA

Specific function: Member of the two-component regulatory system RcsC/RcsB involved in the regulation of the expression of genes involved in colanic acid capsule synthesis. Together with RcsF, RcsC probably functions as a membrane-associated protein kinase that phosphorylat

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI145693157, Length=528, Percent_Identity=32.9545454545455, Blast_Score=259, Evalue=8e-70,
Organism=Escherichia coli, GI1789149, Length=540, Percent_Identity=31.4814814814815, Blast_Score=230, Evalue=4e-61,
Organism=Escherichia coli, GI87081816, Length=243, Percent_Identity=39.5061728395062, Blast_Score=164, Evalue=2e-41,
Organism=Escherichia coli, GI48994928, Length=238, Percent_Identity=36.1344537815126, Blast_Score=155, Evalue=2e-38,
Organism=Escherichia coli, GI1788713, Length=281, Percent_Identity=33.0960854092527, Blast_Score=149, Evalue=1e-36,
Organism=Escherichia coli, GI1788393, Length=243, Percent_Identity=31.2757201646091, Blast_Score=105, Evalue=2e-23,
Organism=Escherichia coli, GI1786912, Length=259, Percent_Identity=28.1853281853282, Blast_Score=87, Evalue=8e-18,
Organism=Escherichia coli, GI87082128, Length=228, Percent_Identity=27.1929824561404, Blast_Score=84, Evalue=9e-17,
Organism=Escherichia coli, GI1790436, Length=229, Percent_Identity=27.9475982532751, Blast_Score=79, Evalue=2e-15,
Organism=Escherichia coli, GI1786783, Length=223, Percent_Identity=27.3542600896861, Blast_Score=79, Evalue=3e-15,
Organism=Escherichia coli, GI1786600, Length=246, Percent_Identity=26.8292682926829, Blast_Score=78, Evalue=3e-15,
Organism=Escherichia coli, GI1787894, Length=235, Percent_Identity=25.1063829787234, Blast_Score=70, Evalue=6e-13,
Organism=Escherichia coli, GI1790861, Length=231, Percent_Identity=29.8701298701299, Blast_Score=69, Evalue=2e-12,
Organism=Escherichia coli, GI1788549, Length=255, Percent_Identity=22.7450980392157, Blast_Score=69, Evalue=2e-12,
Organism=Escherichia coli, GI1790300, Length=254, Percent_Identity=27.5590551181102, Blast_Score=67, Evalue=1e-11,
Organism=Escherichia coli, GI1789808, Length=289, Percent_Identity=25.2595155709343, Blast_Score=65, Evalue=3e-11,
Organism=Saccharomyces cerevisiae, GI6322044, Length=70, Percent_Identity=48.5714285714286, Blast_Score=78, Evalue=1e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011006
- InterPro:   IPR000014
- InterPro:   IPR004358
- InterPro:   IPR019017
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF09456 RcsC; PF00072 Response_reg [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 143542; Mature: 143542

Theoretical pI: Translated: 6.84; Mature: 6.84

Prosite motif: PS50112 PAS ; PS50113 PAC ; PS50110 RESPONSE_REGULATORY ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQPAMALPAKLTVGMLDNGWPPFTMLNAGRAEGIGMDFLHEALRGHQITYSVKGYPDMTA
CCCCCCCCCEEEEEECCCCCCCEEEECCCCCCCCCHHHHHHHHCCCEEEEEECCCCCHHH
LLAALCKGDVDVVLNVAITPARRRCLSFSEPYFDGDAVVVGRPSAALEEDLLASMQTGRF
HHHHHHCCCEEEEEEEEECHHHHHHHCCCCCCCCCCEEEEECCCHHHHHHHHHHHHCCCE
AIEPGYYMEGILRQRYPKARMVPIKDTTDGLRAIVNGRADYYATVQPVAEYAMVSPEFAG
EECCCHHHHHHHHHCCCCCEEEECCCCCHHHHHHHCCCCCEEEEHHHHHHHHHCCCCHHH
LKVLSRYREPTGAIHFAFRSNATELRDATDAGLAAIDPARRAALLAHWITSQVASPDKPQ
HHHHHHHCCCCCEEEEEEECCCHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCC
KFFLTDEERAFLKSLPTLTVGVDAGLAPYTYLDESGRASGIAIDYLSYLGETLGVRFRRQ
EEEECCHHHHHHHHCCCEEEECCCCCCCCEEECCCCCCCCCHHHHHHHHHHHHCCEEECC
PTTDIQQTVEALHQGKIDLMAVAVPEDPTLRGLPVSRPYSTFPVVVAGRNSALPLAHLRD
CCHHHHHHHHHHHCCCEEEEEEECCCCCCCCCCCCCCCCCCCCEEEECCCCCCCHHHHHH
LTGKRVVVTDSGGVGDFTRHEVPGVKLVIAPNVHAGLDMVAQGKADAYVDDIVSTDIELR
CCCCEEEEECCCCCCCCCCCCCCCEEEEECCCCCCCCHHHCCCCCHHHHHHHHHCCHHHH
RNFAGKLRVIGSGEHMLNSGFAVNPALAGRLLPLINRALSVLPEDRRLDIQNRYAGTSYV
HCCCCEEEEEECCCHHHCCCCEECHHHHHHHHHHHHHHHHHCCCCCCCCHHHCCCCCEEE
LETSWLNALWRASPILIGMMVILLILLRSQRLYRKEASIRREAERELSTQLRFQSTLMDA
EEHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IPLPIVVSNKDGRYLRLNAFSEWITGRSWADIVGHTTTEVHFWGEANSARVEEASQRAID
CCCCEEEECCCCCEEEEECHHHHHCCCCHHHHHCCCEEEEEEECCCCCHHHHHHHHHHCC
TGRLVQLQLQLQDKEGVERHFLLYIKPFVGENNVEGLINTGVDVTEIRQAELEAREAQGR
CCCEEEEEEEECCCCCCCEEEEEEEEECCCCCCCCHHCCCCCCHHHHHHHHHHHHHHCCH
LADVTRYLPIMVFQARQSGHLGRGPIWVSGNTTDLFGVDAETLAVNPPTIEACVHPDDRM
HHHHHHHHHHHEEEECCCCCCCCCCEEECCCCCEEEECCCCEEEECCCCEEEECCCCHHH
SLRRAIARARRELQVLNHEVRLRKLEGFRWTRLQAVPRIEIDGSVLWNGYWRDTQAEHER
HHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCEEEECCEEEECCCCCCCHHHHHH
AAALASAKESAEAASRAKDSFLAMMSHEIRTPMNGVLGLAELLSHTSLTPEQSATVGMMG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCCEEEECC
DSASALLQILDDILDYSKIEAGRIDIESRPLDIRELCDCTIGVLATRAHEKGLHLRLHVG
CCHHHHHHHHHHHHHHHHCCCCEEECCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEEEC
ADVAAVVLGDSVRLRQVLFNLLSNAIKFTESGMVSVSAEVVQETETAQTLRWRVTDTGIG
CCEEEEEECCCHHHHHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHEEEEEEEECCCC
IEPQNQSRLFDPFVQADTSTTRRFGGTGLGLAICRRLVQLMGGRITLKSEPGIGTQVEVE
CCCCCCCCCCCHHHHCCCCHHHHCCCCCHHHHHHHHHHHHHCCEEEEECCCCCCCEEEEE
LSLPVKERRYSKPPLAGIQFGVRLRDCAVGQALTDFLSAAGATNSASQDERDKPQMLFLN
EECCHHHHCCCCCCCCHHEECCEEHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEE
DGEYAPPSPVGQASPIVVHVTEKPKLAGYRLTESDVRLSSNPVSWRAINAVTVAAMQGRA
CCCCCCCCCCCCCCCEEEEEECCCCCCCEEECCCCCEECCCCCCEEEEEEEEEEECCCCC
HTVATHAQAKPKPAAHAVTREQALASGRLILVAEDHETNRILLQHQLKLLGYACDAVVDG
EEEEECCCCCCCCHHHHHHHHHHHHCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHCCC
QQALEAAEKTAYAMLITDCHMPNVNGYELARQLRAREAEAKTEAGTDAHRLPIVAITAST
HHHHHHHHHHEEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCC
EAEEVQRCREAGIDECMFKPTQLNALRACLQRWNPDNQDADGRKGSGKA
CHHHHHHHHHCCCHHHHCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MQPAMALPAKLTVGMLDNGWPPFTMLNAGRAEGIGMDFLHEALRGHQITYSVKGYPDMTA
CCCCCCCCCEEEEEECCCCCCCEEEECCCCCCCCCHHHHHHHHCCCEEEEEECCCCCHHH
LLAALCKGDVDVVLNVAITPARRRCLSFSEPYFDGDAVVVGRPSAALEEDLLASMQTGRF
HHHHHHCCCEEEEEEEEECHHHHHHHCCCCCCCCCCEEEEECCCHHHHHHHHHHHHCCCE
AIEPGYYMEGILRQRYPKARMVPIKDTTDGLRAIVNGRADYYATVQPVAEYAMVSPEFAG
EECCCHHHHHHHHHCCCCCEEEECCCCCHHHHHHHCCCCCEEEEHHHHHHHHHCCCCHHH
LKVLSRYREPTGAIHFAFRSNATELRDATDAGLAAIDPARRAALLAHWITSQVASPDKPQ
HHHHHHHCCCCCEEEEEEECCCHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCC
KFFLTDEERAFLKSLPTLTVGVDAGLAPYTYLDESGRASGIAIDYLSYLGETLGVRFRRQ
EEEECCHHHHHHHHCCCEEEECCCCCCCCEEECCCCCCCCCHHHHHHHHHHHHCCEEECC
PTTDIQQTVEALHQGKIDLMAVAVPEDPTLRGLPVSRPYSTFPVVVAGRNSALPLAHLRD
CCHHHHHHHHHHHCCCEEEEEEECCCCCCCCCCCCCCCCCCCCEEEECCCCCCCHHHHHH
LTGKRVVVTDSGGVGDFTRHEVPGVKLVIAPNVHAGLDMVAQGKADAYVDDIVSTDIELR
CCCCEEEEECCCCCCCCCCCCCCCEEEEECCCCCCCCHHHCCCCCHHHHHHHHHCCHHHH
RNFAGKLRVIGSGEHMLNSGFAVNPALAGRLLPLINRALSVLPEDRRLDIQNRYAGTSYV
HCCCCEEEEEECCCHHHCCCCEECHHHHHHHHHHHHHHHHHCCCCCCCCHHHCCCCCEEE
LETSWLNALWRASPILIGMMVILLILLRSQRLYRKEASIRREAERELSTQLRFQSTLMDA
EEHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IPLPIVVSNKDGRYLRLNAFSEWITGRSWADIVGHTTTEVHFWGEANSARVEEASQRAID
CCCCEEEECCCCCEEEEECHHHHHCCCCHHHHHCCCEEEEEEECCCCCHHHHHHHHHHCC
TGRLVQLQLQLQDKEGVERHFLLYIKPFVGENNVEGLINTGVDVTEIRQAELEAREAQGR
CCCEEEEEEEECCCCCCCEEEEEEEEECCCCCCCCHHCCCCCCHHHHHHHHHHHHHHCCH
LADVTRYLPIMVFQARQSGHLGRGPIWVSGNTTDLFGVDAETLAVNPPTIEACVHPDDRM
HHHHHHHHHHHEEEECCCCCCCCCCEEECCCCCEEEECCCCEEEECCCCEEEECCCCHHH
SLRRAIARARRELQVLNHEVRLRKLEGFRWTRLQAVPRIEIDGSVLWNGYWRDTQAEHER
HHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCEEEECCEEEECCCCCCCHHHHHH
AAALASAKESAEAASRAKDSFLAMMSHEIRTPMNGVLGLAELLSHTSLTPEQSATVGMMG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCCEEEECC
DSASALLQILDDILDYSKIEAGRIDIESRPLDIRELCDCTIGVLATRAHEKGLHLRLHVG
CCHHHHHHHHHHHHHHHHCCCCEEECCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEEEC
ADVAAVVLGDSVRLRQVLFNLLSNAIKFTESGMVSVSAEVVQETETAQTLRWRVTDTGIG
CCEEEEEECCCHHHHHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHEEEEEEEECCCC
IEPQNQSRLFDPFVQADTSTTRRFGGTGLGLAICRRLVQLMGGRITLKSEPGIGTQVEVE
CCCCCCCCCCCHHHHCCCCHHHHCCCCCHHHHHHHHHHHHHCCEEEEECCCCCCCEEEEE
LSLPVKERRYSKPPLAGIQFGVRLRDCAVGQALTDFLSAAGATNSASQDERDKPQMLFLN
EECCHHHHCCCCCCCCHHEECCEEHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEE
DGEYAPPSPVGQASPIVVHVTEKPKLAGYRLTESDVRLSSNPVSWRAINAVTVAAMQGRA
CCCCCCCCCCCCCCCEEEEEECCCCCCCEEECCCCCEECCCCCCEEEEEEEEEEECCCCC
HTVATHAQAKPKPAAHAVTREQALASGRLILVAEDHETNRILLQHQLKLLGYACDAVVDG
EEEEECCCCCCCCHHHHHHHHHHHHCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHCCC
QQALEAAEKTAYAMLITDCHMPNVNGYELARQLRAREAEAKTEAGTDAHRLPIVAITAST
HHHHHHHHHHEEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCC
EAEEVQRCREAGIDECMFKPTQLNALRACLQRWNPDNQDADGRKGSGKA
CHHHHHHHHHCCCHHHHCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2404948; 8366025; 9097040; 9278503; 11758943; 11309126; 13129944 [H]