Click here to switch to the map view.

The map label for this gene is czcC2 [H]

Identifier: 94313518

GI number: 94313518

Start: 1216062

End: 1217357

Strand: Direct

Name: czcC2 [H]

Synonym: Rmet_4596

Alternate gene names: 94313518

Gene position: 1216062-1217357 (Clockwise)

Preceding gene: 94313517

Following gene: 94313522

Centisome position: 47.13

GC content: 68.29

Gene sequence:

>1296_bases
ATGAGAAACTTCCTTTCGCCGCCCGGTCTGGCGGCCGTGCTCCTTTGCCTGTCGCTGGGCCCCATCGTCAGTCCTGTCGC
ATCGGCGCAGGGCACGGCGGCCCCTGCACCGGCCCCGGTATGGGTCCAAGTACCTGCTCAGGAACCGCCCAGCGCCTTGA
CGCTGGAAGCCGCGCTGGCGCTGGCCACCGCGCAGAACCCGACGCTGTCCGCCGCCCGCATCGAACTCGATTCGACCGAA
GGCGGCATCACACAGGCACGTGTGATCCCGAACCCCGAGATCGCCGTGCAGATGGAAGACACCCGCGCCGCCACACGCGC
CACCACTGGCCAGGTCAACCTTCCAATCGAACTGGGCGGCAAGCGCAGCGCGCGGATTGGCGCCGCAAACCGCGCGCGCG
ACGTGGCCCAGGCACAGCTTGGCACCACGCAGGCCGACCTGCGGGCCAGCGTGATCGGCGCGTTCTTCAACGTGCTGGTC
GCGCAGGAGCGCGTGCGGCTTGCGGCCGGTTCGGTCGACATCGCCACGCGCGGTGCGAACGCCGCGGCGCGGCGCGTGGC
GGCTGGCAAGATCTCGCCAGTCGAGGAAACCAAGGCACAGGTCGAACTGGCCAACGCGCAGATTGAACGCTCCGAGGCCG
ACGCCGCACTGGTGGCGGCACGGCAGTCGCTCGCCACGCTATGGGGCAATCCGTCGCCACGCTTCACCGAGGCCGATGGC
AACCTCGATGCGTTGCCCGCCCGCCCTCAGGCAACAATGCTGCGCCAATCGCTCGACGGCGCCCCCGCGCTGCTAGCCAG
CGAGCGGGAACTCGATCGCCGGCAGGCCGAAATCAACGTCCAGCGCAGTCGTCAGTACCCGGACGTGACGGTGAGCGTCG
GCGCCAAGCGCGACAACAGTTCGCCGGAGCGCGGCACCTACCCCGTGCTGGGCGTCGCCATTCCGCTGCCGCTGTTCGAC
CGCAACCAAGGCAATCTGTACACAGCCATCCGTCAGGCCGACAAGGCCGCCGACGAACTCCGCGCAACACGCCTTCGGTT
GGATCACGACCTGCAACAGGCCTCGAGCCAACTCGAAGTCTCCCGTTCCTCGGCGCTGAGCCTGCGCGAAACCGTGCTGC
CAGCCGCCGAGCGCGCCTACCAGGCCGCGTCGCAAGGCTTTGAAGCCGGCAAGTTCAATTACCTCGAAGTCCTGGATGCC
CAGCGCACGCTGTTCCAGGCACGCATCCGCTACCTCGGTGTGGTCGCCAATAGCTGGCAAGCCGCTACCACGATCGACCG
CATCCTCGGCCGCTGA

Upstream 100 bases:

>100_bases
TAGCCGGCGAGACGCGGAGAGCCCCTTTCCAATCCACGCGCCCCTGAACGGCGCGCTTGTCGTCTCGCCGATTTTCTCCC
GTTTGCATTGGTGAAACTCG

Downstream 100 bases:

>100_bases
CAGGAACCAACATGACCTTGACTCGAAAACAGGCCATCACCATCGCTGGCATCGTGATCGCCGGCCTGATCGCCGCGCTT
GCCCTGCTGCTCTCCGGCCG

Product: heavy metal cation tricomponent efflux outer membrane porin

Products: NA

Alternate protein names: Cation efflux system protein CzcC [H]

Number of amino acids: Translated: 431; Mature: 431

Protein sequence:

>431_residues
MRNFLSPPGLAAVLLCLSLGPIVSPVASAQGTAAPAPAPVWVQVPAQEPPSALTLEAALALATAQNPTLSAARIELDSTE
GGITQARVIPNPEIAVQMEDTRAATRATTGQVNLPIELGGKRSARIGAANRARDVAQAQLGTTQADLRASVIGAFFNVLV
AQERVRLAAGSVDIATRGANAAARRVAAGKISPVEETKAQVELANAQIERSEADAALVAARQSLATLWGNPSPRFTEADG
NLDALPARPQATMLRQSLDGAPALLASERELDRRQAEINVQRSRQYPDVTVSVGAKRDNSSPERGTYPVLGVAIPLPLFD
RNQGNLYTAIRQADKAADELRATRLRLDHDLQQASSQLEVSRSSALSLRETVLPAAERAYQAASQGFEAGKFNYLEVLDA
QRTLFQARIRYLGVVANSWQAATTIDRILGR

Sequences:

>Translated_431_residues
MRNFLSPPGLAAVLLCLSLGPIVSPVASAQGTAAPAPAPVWVQVPAQEPPSALTLEAALALATAQNPTLSAARIELDSTE
GGITQARVIPNPEIAVQMEDTRAATRATTGQVNLPIELGGKRSARIGAANRARDVAQAQLGTTQADLRASVIGAFFNVLV
AQERVRLAAGSVDIATRGANAAARRVAAGKISPVEETKAQVELANAQIERSEADAALVAARQSLATLWGNPSPRFTEADG
NLDALPARPQATMLRQSLDGAPALLASERELDRRQAEINVQRSRQYPDVTVSVGAKRDNSSPERGTYPVLGVAIPLPLFD
RNQGNLYTAIRQADKAADELRATRLRLDHDLQQASSQLEVSRSSALSLRETVLPAAERAYQAASQGFEAGKFNYLEVLDA
QRTLFQARIRYLGVVANSWQAATTIDRILGR
>Mature_431_residues
MRNFLSPPGLAAVLLCLSLGPIVSPVASAQGTAAPAPAPVWVQVPAQEPPSALTLEAALALATAQNPTLSAARIELDSTE
GGITQARVIPNPEIAVQMEDTRAATRATTGQVNLPIELGGKRSARIGAANRARDVAQAQLGTTQADLRASVIGAFFNVLV
AQERVRLAAGSVDIATRGANAAARRVAAGKISPVEETKAQVELANAQIERSEADAALVAARQSLATLWGNPSPRFTEADG
NLDALPARPQATMLRQSLDGAPALLASERELDRRQAEINVQRSRQYPDVTVSVGAKRDNSSPERGTYPVLGVAIPLPLFD
RNQGNLYTAIRQADKAADELRATRLRLDHDLQQASSQLEVSRSSALSLRETVLPAAERAYQAASQGFEAGKFNYLEVLDA
QRTLFQARIRYLGVVANSWQAATTIDRILGR

Specific function: CzcC protein appears to modify the specificity of the system, perhaps by acting on the CzcB protein. When the CzcC protein is added to CzcA and CzcB, the efflux system gains specificity for cadmium and cobalt [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell outer membrane (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003423 [H]

Pfam domain/function: PF02321 OEP [H]

EC number: NA

Molecular weight: Translated: 45775; Mature: 45775

Theoretical pI: Translated: 9.40; Mature: 9.40

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
0.9 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
0.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRNFLSPPGLAAVLLCLSLGPIVSPVASAQGTAAPAPAPVWVQVPAQEPPSALTLEAALA
CCCCCCCCCHHHHHHHHHHCHHHHHHHHCCCCCCCCCCCEEEECCCCCCCCCEEHHHHHH
LATAQNPTLSAARIELDSTEGGITQARVIPNPEIAVQMEDTRAATRATTGQVNLPIELGG
HHHCCCCCCEEEEEEEECCCCCCEEEEECCCCCEEEEECCCCHHHHCCCCEEEEEEEECC
KRSARIGAANRARDVAQAQLGTTQADLRASVIGAFFNVLVAQERVRLAAGSVDIATRGAN
CCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCC
AAARRVAAGKISPVEETKAQVELANAQIERSEADAALVAARQSLATLWGNPSPRFTEADG
HHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEECCC
NLDALPARPQATMLRQSLDGAPALLASERELDRRQAEINVQRSRQYPDVTVSVGAKRDNS
CCCCCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCC
SPERGTYPVLGVAIPLPLFDRNQGNLYTAIRQADKAADELRATRLRLDHDLQQASSQLEV
CCCCCCCCEEEEEECCCCEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SRSSALSLRETVLPAAERAYQAASQGFEAGKFNYLEVLDAQRTLFQARIRYLGVVANSWQ
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCH
AATTIDRILGR
HHHHHHHHHCC
>Mature Secondary Structure
MRNFLSPPGLAAVLLCLSLGPIVSPVASAQGTAAPAPAPVWVQVPAQEPPSALTLEAALA
CCCCCCCCCHHHHHHHHHHCHHHHHHHHCCCCCCCCCCCEEEECCCCCCCCCEEHHHHHH
LATAQNPTLSAARIELDSTEGGITQARVIPNPEIAVQMEDTRAATRATTGQVNLPIELGG
HHHCCCCCCEEEEEEEECCCCCCEEEEECCCCCEEEEECCCCHHHHCCCCEEEEEEEECC
KRSARIGAANRARDVAQAQLGTTQADLRASVIGAFFNVLVAQERVRLAAGSVDIATRGAN
CCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCC
AAARRVAAGKISPVEETKAQVELANAQIERSEADAALVAARQSLATLWGNPSPRFTEADG
HHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEECCC
NLDALPARPQATMLRQSLDGAPALLASERELDRRQAEINVQRSRQYPDVTVSVGAKRDNS
CCCCCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCC
SPERGTYPVLGVAIPLPLFDRNQGNLYTAIRQADKAADELRATRLRLDHDLQQASSQLEV
CCCCCCCCEEEEEECCCCEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SRSSALSLRETVLPAAERAYQAASQGFEAGKFNYLEVLDAQRTLFQARIRYLGVVANSWQ
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCH
AATTIDRILGR
HHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2678100; 7766206 [H]