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The map label for this gene is yngJ [H]

Identifier: 94313335

GI number: 94313335

Start: 1005072

End: 1006304

Strand: Reverse

Name: yngJ [H]

Synonym: Rmet_4410

Alternate gene names: 94313335

Gene position: 1006304-1005072 (Counterclockwise)

Preceding gene: 94313336

Following gene: 94313334

Centisome position: 39.0

GC content: 65.77

Gene sequence:

>1233_bases
ATGACCTTCGACATCCCCAGCGAGTGGGTGGAATTTGGCGACGCGCTGATCCGCTTTGTCGATCGTGAAGTCGTCGCGCT
CGAAAAGGATCATCGCACCCTGCTGGCTAGCGAACGCACGGTCTATACCGCCGACGGGCGCTATGCCCCGGAGGTGCTGG
CGCTACGCCGCCAGGTACGCATGCGATCGGCCGAACTGGGCTTCTACACCGCGCTGTCCGCCGAAGCGCTCGGCGGTGGC
GGGCTGGGGCCGCAGGCCGCCGTCTACATCCAGGAGCGCCTGAACGCCCACTGCGGCCCCGAGCGCCATCTGGTGCAGAC
CGTGGTGCTGCCCTCCCCATTCACGAATGGGCTGTCGCCGGTACTGAAGCATCTTCATCCGTCGGTCTTCGAAAGCGTGC
AGCCAGAACTGGCCAGCGGCGACAAGACGATGTGCTTCGGGCTTTCCGAACCGGATGCCGGCTCGGACGTCTTTGGCATG
CGCACACGCGCTACGCGCGATGGCGACCACTGGGTGCTCAACGGCACCAAGCAATGGATCACCAACGCGCCCTATGCGGA
CTACGCGATGGTCTTCGCCGTCACCGACGAAGAGAAAGCCCGCGCCCACAAGGGCGGCATCACCGGCTTCTTCCTGCCCA
CCCGCACACCGGGGTTCTCGGTACCGAGCGTGATTCCGACGATGGGACACCTGGGCGCCGACATCGGCATCATCTCGCTG
GAAAACGTGCGCGTGCCGGACACCCACCGCCTCGGGCCGGTCGACCGTGGCCTGTCCGTGGCGCTCGACGGCGTCAACGC
CGGTCGCCTGAGCATGGCCGCCAGTTGCCTCGGCCTGGCCGAGTGGGCGCTGGAACAGGCCGTGGCCTACGCCAAGGTCC
GCAAGACCTTTGGGCAGCCTATCGGCGACCACCAGGCCGTGCAGATCATGCTAGCCGAATGCGCGATGGACATCTACGCC
ACCAAATCGATGGTCCGCCACTGCGCCTGGCTGGTGGACAACGATCTGCCCGCCACAAAGGAGGTCTCCATCATCAAGGC
ATCGTCCACGGAGATGGCCGGGCGTGTCTTCGACCGGGCAATGCAGATTCACGGCGGCATGGGTCTGACCAACGAACTGC
GACTCGAGGCCGGCTACCGCTTCGTGCGCACGATGCGCATTCCCGATGGCACCTCCGAGATCCAGCGGCGCACCATCGCG
CGGCGTCTGCTCGACGGCGACACGGCTTTCTGA

Upstream 100 bases:

>100_bases
TCAACCCCGTATTCGCCATGCCGGCAGGACAAGGCGCATTCGCCGCCGACGCCGTCATCGACGTAACCCCACCCCAATCC
TCATCAGGAGACCTTGCATC

Downstream 100 bases:

>100_bases
CCGGCGACGCGCGCGACTGCCCCAATACAAGACAAAAGACACCAAGGAGACTGCCATGCGAACCAGCGACACCAAGGACA
CCAAGGACACCAAGAACGCC

Product: acyl-CoA dehydrogenase

Products: 2,3-dehydroacyl-CoA; reduced acceptor

Alternate protein names: NA

Number of amino acids: Translated: 410; Mature: 409

Protein sequence:

>410_residues
MTFDIPSEWVEFGDALIRFVDREVVALEKDHRTLLASERTVYTADGRYAPEVLALRRQVRMRSAELGFYTALSAEALGGG
GLGPQAAVYIQERLNAHCGPERHLVQTVVLPSPFTNGLSPVLKHLHPSVFESVQPELASGDKTMCFGLSEPDAGSDVFGM
RTRATRDGDHWVLNGTKQWITNAPYADYAMVFAVTDEEKARAHKGGITGFFLPTRTPGFSVPSVIPTMGHLGADIGIISL
ENVRVPDTHRLGPVDRGLSVALDGVNAGRLSMAASCLGLAEWALEQAVAYAKVRKTFGQPIGDHQAVQIMLAECAMDIYA
TKSMVRHCAWLVDNDLPATKEVSIIKASSTEMAGRVFDRAMQIHGGMGLTNELRLEAGYRFVRTMRIPDGTSEIQRRTIA
RRLLDGDTAF

Sequences:

>Translated_410_residues
MTFDIPSEWVEFGDALIRFVDREVVALEKDHRTLLASERTVYTADGRYAPEVLALRRQVRMRSAELGFYTALSAEALGGG
GLGPQAAVYIQERLNAHCGPERHLVQTVVLPSPFTNGLSPVLKHLHPSVFESVQPELASGDKTMCFGLSEPDAGSDVFGM
RTRATRDGDHWVLNGTKQWITNAPYADYAMVFAVTDEEKARAHKGGITGFFLPTRTPGFSVPSVIPTMGHLGADIGIISL
ENVRVPDTHRLGPVDRGLSVALDGVNAGRLSMAASCLGLAEWALEQAVAYAKVRKTFGQPIGDHQAVQIMLAECAMDIYA
TKSMVRHCAWLVDNDLPATKEVSIIKASSTEMAGRVFDRAMQIHGGMGLTNELRLEAGYRFVRTMRIPDGTSEIQRRTIA
RRLLDGDTAF
>Mature_409_residues
TFDIPSEWVEFGDALIRFVDREVVALEKDHRTLLASERTVYTADGRYAPEVLALRRQVRMRSAELGFYTALSAEALGGGG
LGPQAAVYIQERLNAHCGPERHLVQTVVLPSPFTNGLSPVLKHLHPSVFESVQPELASGDKTMCFGLSEPDAGSDVFGMR
TRATRDGDHWVLNGTKQWITNAPYADYAMVFAVTDEEKARAHKGGITGFFLPTRTPGFSVPSVIPTMGHLGADIGIISLE
NVRVPDTHRLGPVDRGLSVALDGVNAGRLSMAASCLGLAEWALEQAVAYAKVRKTFGQPIGDHQAVQIMLAECAMDIYAT
KSMVRHCAWLVDNDLPATKEVSIIKASSTEMAGRVFDRAMQIHGGMGLTNELRLEAGYRFVRTMRIPDGTSEIQRRTIAR
RLLDGDTAF

Specific function: Unknown

COG id: COG1960

COG function: function code I; Acyl-CoA dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4557233, Length=387, Percent_Identity=34.8837209302326, Blast_Score=198, Evalue=8e-51,
Organism=Homo sapiens, GI4557231, Length=407, Percent_Identity=31.4496314496315, Blast_Score=174, Evalue=1e-43,
Organism=Homo sapiens, GI187960098, Length=406, Percent_Identity=31.0344827586207, Blast_Score=174, Evalue=2e-43,
Organism=Homo sapiens, GI4501859, Length=269, Percent_Identity=33.457249070632, Blast_Score=159, Evalue=5e-39,
Organism=Homo sapiens, GI226958414, Length=271, Percent_Identity=33.5793357933579, Blast_Score=157, Evalue=1e-38,
Organism=Homo sapiens, GI226958412, Length=271, Percent_Identity=33.5793357933579, Blast_Score=157, Evalue=1e-38,
Organism=Homo sapiens, GI4501857, Length=381, Percent_Identity=28.6089238845144, Blast_Score=148, Evalue=1e-35,
Organism=Homo sapiens, GI21361497, Length=271, Percent_Identity=33.9483394833948, Blast_Score=140, Evalue=3e-33,
Organism=Homo sapiens, GI4557235, Length=342, Percent_Identity=32.4561403508772, Blast_Score=133, Evalue=4e-31,
Organism=Homo sapiens, GI76496475, Length=342, Percent_Identity=32.4561403508772, Blast_Score=133, Evalue=4e-31,
Organism=Homo sapiens, GI7656849, Length=272, Percent_Identity=30.1470588235294, Blast_Score=130, Evalue=3e-30,
Organism=Homo sapiens, GI4503943, Length=286, Percent_Identity=29.7202797202797, Blast_Score=120, Evalue=3e-27,
Organism=Homo sapiens, GI7669494, Length=257, Percent_Identity=31.5175097276265, Blast_Score=119, Evalue=5e-27,
Organism=Homo sapiens, GI211971008, Length=273, Percent_Identity=28.9377289377289, Blast_Score=110, Evalue=2e-24,
Organism=Homo sapiens, GI48976061, Length=273, Percent_Identity=28.9377289377289, Blast_Score=110, Evalue=2e-24,
Organism=Homo sapiens, GI38505218, Length=272, Percent_Identity=28.6764705882353, Blast_Score=107, Evalue=1e-23,
Organism=Escherichia coli, GI87081958, Length=274, Percent_Identity=31.3868613138686, Blast_Score=122, Evalue=4e-29,
Organism=Escherichia coli, GI1786223, Length=344, Percent_Identity=28.1976744186047, Blast_Score=115, Evalue=4e-27,
Organism=Caenorhabditis elegans, GI17570075, Length=404, Percent_Identity=28.4653465346535, Blast_Score=165, Evalue=4e-41,
Organism=Caenorhabditis elegans, GI17569725, Length=404, Percent_Identity=29.2079207920792, Blast_Score=164, Evalue=6e-41,
Organism=Caenorhabditis elegans, GI17534899, Length=348, Percent_Identity=31.0344827586207, Blast_Score=161, Evalue=5e-40,
Organism=Caenorhabditis elegans, GI17508101, Length=256, Percent_Identity=35.15625, Blast_Score=161, Evalue=6e-40,
Organism=Caenorhabditis elegans, GI17533517, Length=395, Percent_Identity=29.873417721519, Blast_Score=160, Evalue=1e-39,
Organism=Caenorhabditis elegans, GI17506239, Length=273, Percent_Identity=33.6996336996337, Blast_Score=152, Evalue=3e-37,
Organism=Caenorhabditis elegans, GI17538396, Length=269, Percent_Identity=34.9442379182156, Blast_Score=151, Evalue=6e-37,
Organism=Caenorhabditis elegans, GI71985184, Length=348, Percent_Identity=31.0344827586207, Blast_Score=149, Evalue=3e-36,
Organism=Caenorhabditis elegans, GI71990804, Length=201, Percent_Identity=34.3283582089552, Blast_Score=129, Evalue=4e-30,
Organism=Caenorhabditis elegans, GI17534353, Length=384, Percent_Identity=28.90625, Blast_Score=127, Evalue=1e-29,
Organism=Caenorhabditis elegans, GI71985192, Length=280, Percent_Identity=29.6428571428571, Blast_Score=116, Evalue=2e-26,
Organism=Caenorhabditis elegans, GI17505929, Length=365, Percent_Identity=27.6712328767123, Blast_Score=114, Evalue=1e-25,
Organism=Caenorhabditis elegans, GI17551932, Length=342, Percent_Identity=28.0701754385965, Blast_Score=112, Evalue=2e-25,
Organism=Caenorhabditis elegans, GI32563615, Length=173, Percent_Identity=35.8381502890173, Blast_Score=112, Evalue=3e-25,
Organism=Caenorhabditis elegans, GI71982178, Length=163, Percent_Identity=36.8098159509202, Blast_Score=108, Evalue=4e-24,
Organism=Caenorhabditis elegans, GI17531909, Length=242, Percent_Identity=30.5785123966942, Blast_Score=108, Evalue=4e-24,
Organism=Caenorhabditis elegans, GI17562446, Length=271, Percent_Identity=27.6752767527675, Blast_Score=97, Evalue=2e-20,
Organism=Drosophila melanogaster, GI21356377, Length=384, Percent_Identity=34.375, Blast_Score=199, Evalue=3e-51,
Organism=Drosophila melanogaster, GI24646207, Length=388, Percent_Identity=33.7628865979381, Blast_Score=177, Evalue=1e-44,
Organism=Drosophila melanogaster, GI24660351, Length=260, Percent_Identity=36.9230769230769, Blast_Score=172, Evalue=3e-43,
Organism=Drosophila melanogaster, GI24666513, Length=267, Percent_Identity=34.4569288389513, Blast_Score=153, Evalue=2e-37,
Organism=Drosophila melanogaster, GI21355753, Length=286, Percent_Identity=34.6153846153846, Blast_Score=148, Evalue=5e-36,
Organism=Drosophila melanogaster, GI281363737, Length=293, Percent_Identity=33.1058020477816, Blast_Score=142, Evalue=5e-34,
Organism=Drosophila melanogaster, GI19920834, Length=274, Percent_Identity=30.6569343065693, Blast_Score=114, Evalue=1e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: 1.3.99.3

Molecular weight: Translated: 44812; Mature: 44681

Theoretical pI: Translated: 6.65; Mature: 6.65

Prosite motif: PS00072 ACYL_COA_DH_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTFDIPSEWVEFGDALIRFVDREVVALEKDHRTLLASERTVYTADGRYAPEVLALRRQVR
CCCCCHHHHHHHHHHHHHHHHHHHEEECCCCHHEEECCCEEEEECCCCCHHHHHHHHHHH
MRSAELGFYTALSAEALGGGGLGPQAAVYIQERLNAHCGPERHLVQTVVLPSPFTNGLSP
HHHHHCCEEEEECHHHCCCCCCCCHHHHHHHHHHCCCCCCCHHEEEEEECCCCCCCCHHH
VLKHLHPSVFESVQPELASGDKTMCFGLSEPDAGSDVFGMRTRATRDGDHWVLNGTKQWI
HHHHHCHHHHHHCCCHHHCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCEEEECCCHHHH
TNAPYADYAMVFAVTDEEKARAHKGGITGFFLPTRTPGFSVPSVIPTMGHLGADIGIISL
CCCCCCCEEEEEEECCHHHHHHHCCCCEEEEECCCCCCCCCCHHHHHHHHCCCCEEEEEE
ENVRVPDTHRLGPVDRGLSVALDGVNAGRLSMAASCLGLAEWALEQAVAYAKVRKTFGQP
CCCCCCCCCCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
IGDHQAVQIMLAECAMDIYATKSMVRHCAWLVDNDLPATKEVSIIKASSTEMAGRVFDRA
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCHHHHHHHHHHH
MQIHGGMGLTNELRLEAGYRFVRTMRIPDGTSEIQRRTIARRLLDGDTAF
HHHCCCCCCCHHHHHHHCCEEEEEEECCCCHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure 
TFDIPSEWVEFGDALIRFVDREVVALEKDHRTLLASERTVYTADGRYAPEVLALRRQVR
CCCCHHHHHHHHHHHHHHHHHHHEEECCCCHHEEECCCEEEEECCCCCHHHHHHHHHHH
MRSAELGFYTALSAEALGGGGLGPQAAVYIQERLNAHCGPERHLVQTVVLPSPFTNGLSP
HHHHHCCEEEEECHHHCCCCCCCCHHHHHHHHHHCCCCCCCHHEEEEEECCCCCCCCHHH
VLKHLHPSVFESVQPELASGDKTMCFGLSEPDAGSDVFGMRTRATRDGDHWVLNGTKQWI
HHHHHCHHHHHHCCCHHHCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCEEEECCCHHHH
TNAPYADYAMVFAVTDEEKARAHKGGITGFFLPTRTPGFSVPSVIPTMGHLGADIGIISL
CCCCCCCEEEEEEECCHHHHHHHCCCCEEEEECCCCCCCCCCHHHHHHHHCCCCEEEEEE
ENVRVPDTHRLGPVDRGLSVALDGVNAGRLSMAASCLGLAEWALEQAVAYAKVRKTFGQP
CCCCCCCCCCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
IGDHQAVQIMLAECAMDIYATKSMVRHCAWLVDNDLPATKEVSIIKASSTEMAGRVFDRA
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCHHHHHHHHHHH
MQIHGGMGLTNELRLEAGYRFVRTMRIPDGTSEIQRRTIARRLLDGDTAF
HHHCCCCCCCHHHHHHHCCEEEEEEECCCCHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: acyl-CoA; acceptor

Specific reaction: acyl-CoA + acceptor = 2,3-dehydroacyl-CoA + reduced acceptor

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9387222; 9384377 [H]