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The map label for this gene is fabF [H]

Identifier: 94313314

GI number: 94313314

Start: 986726

End: 987916

Strand: Direct

Name: fabF [H]

Synonym: Rmet_4389

Alternate gene names: 94313314

Gene position: 986726-987916 (Clockwise)

Preceding gene: 94313313

Following gene: 94313315

Centisome position: 38.24

GC content: 68.35

Gene sequence:

>1191_bases
ATGACGATCTATCTGAACGCAATGAACGTGATATGCGCGCTCGGTAGCGGCAGCGACGCCGTGCGTGCCGCGCTGTGGCG
CAGTGACTGTCCGTTTGGTGGCGAGGTCACCGAACGCTATACGCCGGGCAGTCCGCTGCATCTGGGCACCGTTGCAGAGC
CCATGGCGGCCACCGACCTTCCGGCGGGCACCGCGCTGGAACTGGCCAGCCGCAACAACGCCATGCTGGAGCGCACGCTT
GCCGGCTTGCGTCCGGCGGTGGATGCGGCCATCGCGCGGGTGGGCCCGATGCGGGTGGCGATCGTGCTCGGTACCAGCAC
GTCCGGCATCTACGAGGGCGAGCTTGCCGTGCGCACGCACGCGAAAGAGGGCACGTGGCCCGAGCAGTTCCACTACGCCC
AGCAGGAGCTTGGCTCGCCGGCCCGGTATCTGGCCTGGCGGCTCGGCGTCGGCGGGCCTGCCTACACGATTTCCACGGCG
TGCTCGTCCAGCGCCAAGGCCATGTCGGCCGCGGCCCGCCTGATCGAGCACGGCATCGTCGACGTGGCAATCGCCGGTGG
TGTCGACACGCTGTGCACGTTTACGATTTCCGGTTTCCTTTCGCTCGATTCGGTGAGCGCCGAGCGGTGCAACCCGCTGT
CGGCGAACCGGCGTGGCATCAATCTGGGAGAGGGCGCGGGGTTGTTCCTGATGTCCCGCGAGGCCGGGCCCGTGCGGCTG
ACCGGCTGGGGCGAGACTTCGGATGCCCACCATATGTCCGCACCCGACCCATCGGGTGTCGGCGCGCGGACGGCCATGCA
GCAGGCGCTGGCTCGCGCCGGACTGAAGCCCGCGGACATCGACTATCTGAACCTGCACGGAACCGCCACCGAGCAGAACG
ACGTGATGGAAGCGCGTGCGGTGTCCGACCTGTTCGGCGCCGGTGTGCCGGTCAGTTCCACCAAGTCGCAGACCGGGCAC
ACGCTTGGGGCCGCCGGCGCGGTGGAAGCCGCACTGCTGTACCTGACGCTGACGGACAACCCCCGGGGTCGCCTGCCGCC
GCACTGGTGGGATGGCATCGCCGACCCCGCGATGCCGCCGCTGCATGTGGTGGGCGCTGACGAATCCCTGGGCCGGCCGG
TGCGCCATGCGGTGAGCAATTCATTTGCGTTTGGGGGTAGCAATTGCGTATTGGTGATGGGGGAGGGCTAA

Upstream 100 bases:

>100_bases
CCGAAGTGCGCTATCCGGATGCCACCACCACGCTGTTCACGCAGCGGCGTGACGGCTATCGGCTGACCATTCGCACGTTG
CAGGAAGAAGGAAAGACGCC

Downstream 100 bases:

>100_bases
AGATGCGCACACCCGCACCGATATCGACCTTGCCGCCCGTTGGCGAGCTGGTGCCGCATGACGGCGCGATGCGTCTGATC
GACGAACTGCTGGCAGCCGA

Product: 3-oxoacyl-(acyl-carrier-protein) synthase II

Products: NA

Alternate protein names: 3-oxoacyl-[acyl-carrier-protein] synthase II; Beta-ketoacyl-ACP synthase II; KAS II [H]

Number of amino acids: Translated: 396; Mature: 395

Protein sequence:

>396_residues
MTIYLNAMNVICALGSGSDAVRAALWRSDCPFGGEVTERYTPGSPLHLGTVAEPMAATDLPAGTALELASRNNAMLERTL
AGLRPAVDAAIARVGPMRVAIVLGTSTSGIYEGELAVRTHAKEGTWPEQFHYAQQELGSPARYLAWRLGVGGPAYTISTA
CSSSAKAMSAAARLIEHGIVDVAIAGGVDTLCTFTISGFLSLDSVSAERCNPLSANRRGINLGEGAGLFLMSREAGPVRL
TGWGETSDAHHMSAPDPSGVGARTAMQQALARAGLKPADIDYLNLHGTATEQNDVMEARAVSDLFGAGVPVSSTKSQTGH
TLGAAGAVEAALLYLTLTDNPRGRLPPHWWDGIADPAMPPLHVVGADESLGRPVRHAVSNSFAFGGSNCVLVMGEG

Sequences:

>Translated_396_residues
MTIYLNAMNVICALGSGSDAVRAALWRSDCPFGGEVTERYTPGSPLHLGTVAEPMAATDLPAGTALELASRNNAMLERTL
AGLRPAVDAAIARVGPMRVAIVLGTSTSGIYEGELAVRTHAKEGTWPEQFHYAQQELGSPARYLAWRLGVGGPAYTISTA
CSSSAKAMSAAARLIEHGIVDVAIAGGVDTLCTFTISGFLSLDSVSAERCNPLSANRRGINLGEGAGLFLMSREAGPVRL
TGWGETSDAHHMSAPDPSGVGARTAMQQALARAGLKPADIDYLNLHGTATEQNDVMEARAVSDLFGAGVPVSSTKSQTGH
TLGAAGAVEAALLYLTLTDNPRGRLPPHWWDGIADPAMPPLHVVGADESLGRPVRHAVSNSFAFGGSNCVLVMGEG
>Mature_395_residues
TIYLNAMNVICALGSGSDAVRAALWRSDCPFGGEVTERYTPGSPLHLGTVAEPMAATDLPAGTALELASRNNAMLERTLA
GLRPAVDAAIARVGPMRVAIVLGTSTSGIYEGELAVRTHAKEGTWPEQFHYAQQELGSPARYLAWRLGVGGPAYTISTAC
SSSAKAMSAAARLIEHGIVDVAIAGGVDTLCTFTISGFLSLDSVSAERCNPLSANRRGINLGEGAGLFLMSREAGPVRLT
GWGETSDAHHMSAPDPSGVGARTAMQQALARAGLKPADIDYLNLHGTATEQNDVMEARAVSDLFGAGVPVSSTKSQTGHT
LGAAGAVEAALLYLTLTDNPRGRLPPHWWDGIADPAMPPLHVVGADESLGRPVRHAVSNSFAFGGSNCVLVMGEG

Specific function: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP [H]

COG id: COG0304

COG function: function code IQ; 3-oxoacyl-(acyl-carrier-protein) synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the beta-ketoacyl-ACP synthases family [H]

Homologues:

Organism=Homo sapiens, GI8923559, Length=268, Percent_Identity=35.8208955223881, Blast_Score=144, Evalue=1e-34,
Organism=Homo sapiens, GI223972627, Length=150, Percent_Identity=40.6666666666667, Blast_Score=94, Evalue=2e-19,
Organism=Homo sapiens, GI41872631, Length=269, Percent_Identity=28.2527881040892, Blast_Score=72, Evalue=7e-13,
Organism=Escherichia coli, GI1787337, Length=271, Percent_Identity=37.6383763837638, Blast_Score=125, Evalue=5e-30,
Organism=Escherichia coli, GI1788663, Length=266, Percent_Identity=34.9624060150376, Blast_Score=110, Evalue=1e-25,
Organism=Caenorhabditis elegans, GI71983541, Length=276, Percent_Identity=32.2463768115942, Blast_Score=123, Evalue=2e-28,
Organism=Caenorhabditis elegans, GI71983535, Length=264, Percent_Identity=32.1969696969697, Blast_Score=115, Evalue=5e-26,
Organism=Caenorhabditis elegans, GI212642053, Length=264, Percent_Identity=26.5151515151515, Blast_Score=81, Evalue=8e-16,
Organism=Saccharomyces cerevisiae, GI6320904, Length=273, Percent_Identity=30.7692307692308, Blast_Score=124, Evalue=2e-29,
Organism=Drosophila melanogaster, GI24644341, Length=272, Percent_Identity=34.1911764705882, Blast_Score=135, Evalue=5e-32,
Organism=Drosophila melanogaster, GI221330659, Length=268, Percent_Identity=26.1194029850746, Blast_Score=73, Evalue=3e-13,
Organism=Drosophila melanogaster, GI19920632, Length=268, Percent_Identity=26.1194029850746, Blast_Score=73, Evalue=3e-13,
Organism=Drosophila melanogaster, GI24581345, Length=270, Percent_Identity=25.5555555555556, Blast_Score=70, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017568
- InterPro:   IPR000794
- InterPro:   IPR018201
- InterPro:   IPR014031
- InterPro:   IPR014030
- InterPro:   IPR016039
- InterPro:   IPR016038 [H]

Pfam domain/function: PF00109 ketoacyl-synt; PF02801 Ketoacyl-synt_C [H]

EC number: =2.3.1.179 [H]

Molecular weight: Translated: 41112; Mature: 40981

Theoretical pI: Translated: 5.95; Mature: 5.95

Prosite motif: PS00606 B_KETOACYL_SYNTHASE ; PS00237 G_PROTEIN_RECEP_F1_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTIYLNAMNVICALGSGSDAVRAALWRSDCPFGGEVTERYTPGSPLHLGTVAEPMAATDL
CEEEEEEEEEEEEECCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCEECCCCCCCHHHCCC
PAGTALELASRNNAMLERTLAGLRPAVDAAIARVGPMRVAIVLGTSTSGIYEGELAVRTH
CCCCEEEECCCCCHHHHHHHHHCCHHHHHHHHHCCCEEEEEEEECCCCCEEECEEEEEEC
AKEGTWPEQFHYAQQELGSPARYLAWRLGVGGPAYTISTACSSSAKAMSAAARLIEHGIV
CCCCCCHHHHHHHHHHHCCCHHHHEEEECCCCCCEEEEHHHCCHHHHHHHHHHHHHCCCE
DVAIAGGVDTLCTFTISGFLSLDSVSAERCNPLSANRRGINLGEGAGLFLMSREAGPVRL
EEEEECCHHHHHHHHHHHHEEECCCCHHHCCCCCCCCCCCCCCCCCCEEEEECCCCCEEE
TGWGETSDAHHMSAPDPSGVGARTAMQQALARAGLKPADIDYLNLHGTATEQNDVMEARA
EECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCEEEEECCCCCCCHHHHHHHH
VSDLFGAGVPVSSTKSQTGHTLGAAGAVEAALLYLTLTDNPRGRLPPHWWDGIADPAMPP
HHHHHHCCCCCCCCCCCCCCCCCCHHHHEEEEEEEEECCCCCCCCCCHHHCCCCCCCCCC
LHVVGADESLGRPVRHAVSNSFAFGGSNCVLVMGEG
EEEEECCHHHCHHHHHHHHCCCEECCCCEEEEEECC
>Mature Secondary Structure 
TIYLNAMNVICALGSGSDAVRAALWRSDCPFGGEVTERYTPGSPLHLGTVAEPMAATDL
EEEEEEEEEEEEECCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCEECCCCCCCHHHCCC
PAGTALELASRNNAMLERTLAGLRPAVDAAIARVGPMRVAIVLGTSTSGIYEGELAVRTH
CCCCEEEECCCCCHHHHHHHHHCCHHHHHHHHHCCCEEEEEEEECCCCCEEECEEEEEEC
AKEGTWPEQFHYAQQELGSPARYLAWRLGVGGPAYTISTACSSSAKAMSAAARLIEHGIV
CCCCCCHHHHHHHHHHHCCCHHHHEEEECCCCCCEEEEHHHCCHHHHHHHHHHHHHCCCE
DVAIAGGVDTLCTFTISGFLSLDSVSAERCNPLSANRRGINLGEGAGLFLMSREAGPVRL
EEEEECCHHHHHHHHHHHHEEECCCCHHHCCCCCCCCCCCCCCCCCCEEEEECCCCCEEE
TGWGETSDAHHMSAPDPSGVGARTAMQQALARAGLKPADIDYLNLHGTATEQNDVMEARA
EECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCEEEEECCCCCCCHHHHHHHH
VSDLFGAGVPVSSTKSQTGHTLGAAGAVEAALLYLTLTDNPRGRLPPHWWDGIADPAMPP
HHHHHHCCCCCCCCCCCCCCCCCCHHHHEEEEEEEEECCCCCCCCCCHHHCCCCCCCCCC
LHVVGADESLGRPVRHAVSNSFAFGGSNCVLVMGEG
EEEEECCHHHCHHHHHHHHCCCEECCCCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA