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The map label for this gene is rcsB [H]

Identifier: 94313156

GI number: 94313156

Start: 814677

End: 815324

Strand: Reverse

Name: rcsB [H]

Synonym: Rmet_4229

Alternate gene names: 94313156

Gene position: 815324-814677 (Counterclockwise)

Preceding gene: 94313157

Following gene: 94313155

Centisome position: 31.6

GC content: 60.03

Gene sequence:

>648_bases
ATGAACCAAGCCCCCAAAGTACTGGTCTGCGATGATCACCCCATCATTGTGATCGCCCTCCGCAGTGAACTTGCCCGCAT
AGGACAGTTCTCGGAGGTGGTCACTGCCTCCAGTGTCAATGAGATCCTCAATGCGCTGAACGATCCAGAAGTGGGTATTG
TCATCACCGACTTCTCCCTCAACGAAGCGGGTGACGGGCTGCAACTCATCGGACGCATCAAGCGTATGCGTCCCGATGTA
GCCGTGATCGTGTTCTCTATGAACGCCTCGCCGCCGGCCGTCCGCGACATGATAGCCGCGGGTGCCTCCGCCTTCGTCTC
GAAAACCTGCGGTACTCGGGACGTTGCCGAGGCTTGCCGCGTTGTCCTTGCGGGCAGGAAGTTCGTTGCTCCGGCCTCGC
TGGCGCATCTCCTCGACCAGGACGACGGAGGCACGCCACAAGCTGCGCTGCAGCGACTAAGCCCGCGTGAGCGAGAGGTA
TTGCGCCTGCTCGCGCAGGGGCTCTCGCTCAGAGAAATCGCGGCGCGTTTTAACCGAAGCAGGAAAACCATCAGCGTGCA
AAAGTGCGCTGCCATGGCAAAGCTCGGGCTGACGCATGATATGGAGCTCGGACGCTATCTTGCCTCGGCAGACTCAGACG
AACTGTAG

Upstream 100 bases:

>100_bases
GAAATGGCAAGTGAATGGTACTAGGCGCGGAGCGATGCAGCGGCTCCTTGCCTAAATTTGTTTGACCACACTGCCCAATG
CCTCGAACGCGGGGTCACGA

Downstream 100 bases:

>100_bases
CGGGCCTGCCTATCGTGCAGAACAGCTTTGCGCGGAAGTCTCTGAGTACACTGACTACATACGTTGCATGCAGGCGAGCG
AGCGTTGTCCATAGACATAC

Product: Two component transcriptional regulator, Signal receiver domain LuxR family

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 215; Mature: 215

Protein sequence:

>215_residues
MNQAPKVLVCDDHPIIVIALRSELARIGQFSEVVTASSVNEILNALNDPEVGIVITDFSLNEAGDGLQLIGRIKRMRPDV
AVIVFSMNASPPAVRDMIAAGASAFVSKTCGTRDVAEACRVVLAGRKFVAPASLAHLLDQDDGGTPQAALQRLSPREREV
LRLLAQGLSLREIAARFNRSRKTISVQKCAAMAKLGLTHDMELGRYLASADSDEL

Sequences:

>Translated_215_residues
MNQAPKVLVCDDHPIIVIALRSELARIGQFSEVVTASSVNEILNALNDPEVGIVITDFSLNEAGDGLQLIGRIKRMRPDV
AVIVFSMNASPPAVRDMIAAGASAFVSKTCGTRDVAEACRVVLAGRKFVAPASLAHLLDQDDGGTPQAALQRLSPREREV
LRLLAQGLSLREIAARFNRSRKTISVQKCAAMAKLGLTHDMELGRYLASADSDEL
>Mature_215_residues
MNQAPKVLVCDDHPIIVIALRSELARIGQFSEVVTASSVNEILNALNDPEVGIVITDFSLNEAGDGLQLIGRIKRMRPDV
AVIVFSMNASPPAVRDMIAAGASAFVSKTCGTRDVAEACRVVLAGRKFVAPASLAHLLDQDDGGTPQAALQRLSPREREV
LRLLAQGLSLREIAARFNRSRKTISVQKCAAMAKLGLTHDMELGRYLASADSDEL

Specific function: Also stimulates ftsZ expression. This suggests that rcsB is a regulator implicated in the regulation of more than one cellular function [H]

COG id: COG2197

COG function: function code TK; Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788546, Length=205, Percent_Identity=37.0731707317073, Blast_Score=130, Evalue=8e-32,
Organism=Escherichia coli, GI1786747, Length=200, Percent_Identity=30.5, Blast_Score=91, Evalue=6e-20,
Organism=Escherichia coli, GI1790102, Length=209, Percent_Identity=30.622009569378, Blast_Score=79, Evalue=3e-16,
Organism=Escherichia coli, GI1788222, Length=198, Percent_Identity=26.7676767676768, Blast_Score=78, Evalue=4e-16,
Organism=Escherichia coli, GI1788521, Length=193, Percent_Identity=25.9067357512953, Blast_Score=60, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR016032
- InterPro:   IPR001789
- InterPro:   IPR000792
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00196 GerE; PF00072 Response_reg [H]

EC number: NA

Molecular weight: Translated: 23088; Mature: 23088

Theoretical pI: Translated: 7.39; Mature: 7.39

Prosite motif: PS00014 ER_TARGET ; PS50110 RESPONSE_REGULATORY ; PS50043 HTH_LUXR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNQAPKVLVCDDHPIIVIALRSELARIGQFSEVVTASSVNEILNALNDPEVGIVITDFSL
CCCCCEEEEECCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCC
NEAGDGLQLIGRIKRMRPDVAVIVFSMNASPPAVRDMIAAGASAFVSKTCGTRDVAEACR
CCCCCHHHHHHHHHHHCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
VVLAGRKFVAPASLAHLLDQDDGGTPQAALQRLSPREREVLRLLAQGLSLREIAARFNRS
HHHHCCCCCCHHHHHHHHCCCCCCCHHHHHHHCCCHHHHHHHHHHCCCCHHHHHHHHCCC
RKTISVQKCAAMAKLGLTHDMELGRYLASADSDEL
CCCHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MNQAPKVLVCDDHPIIVIALRSELARIGQFSEVVTASSVNEILNALNDPEVGIVITDFSL
CCCCCEEEEECCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCC
NEAGDGLQLIGRIKRMRPDVAVIVFSMNASPPAVRDMIAAGASAFVSKTCGTRDVAEACR
CCCCCHHHHHHHHHHHCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
VVLAGRKFVAPASLAHLLDQDDGGTPQAALQRLSPREREVLRLLAQGLSLREIAARFNRS
HHHHCCCCCCHHHHHHHHCCCCCCCHHHHHHHCCCHHHHHHHHHHCCCCHHHHHHHHCCC
RKTISVQKCAAMAKLGLTHDMELGRYLASADSDEL
CCCHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]