Click here to switch to the map view.

The map label for this gene is rcsC [H]

Identifier: 94313142

GI number: 94313142

Start: 799386

End: 799838

Strand: Direct

Name: rcsC [H]

Synonym: Rmet_4215

Alternate gene names: 94313142

Gene position: 799386-799838 (Clockwise)

Preceding gene: 94313141

Following gene: 94313144

Centisome position: 30.98

GC content: 66.0

Gene sequence:

>453_bases
TTGCCACGTACCGTGTCCAAGCCTGCCAATAACCTGCCGTTGCCGCGCGTCATCGTCGCGGAGGATCATCCCGTATGCCT
GCTCGTGCTGGAGGACCAGCTCAAGGGCATTGGTGGCTGCGAGGTGGTGCTCTGCGAGAACGGTGCCGACGCGCTCAGGG
CGCTGGAAAGCGGCCCGGCCGCGCTGTTGCTGACTGACCTCAGCCTGCCCGGCATCGAAGGACTGGCGCTCGCGCGCAGA
ATCCGCACGGGCAAGGCGGGGCAGGTGGCCCCCGACCTGCCCATCGTCGCCATCACGGCCACCGCTGGACCCGAGGAGCG
ACTCGCATGCCTGGAGGCCGGCATCGGCATGGTGCTGACGAAGCCGGTCAGCTACGAGACGCTCCAGTCGGTCCTGGGTC
GCTACCTTGGGAAAGACGACCAGTACGATCAATACGAGCAATACGACCGATAG

Upstream 100 bases:

>100_bases
GGGGCTGCAGAAAAGGCTGCAAACTGAAGCGGGAAGTTGCGGAGTTTTCAGCAACCTCGCCGCGGCGTCGACATGCACAA
TATCGACAGCCGAATTTCTG

Downstream 100 bases:

>100_bases
CGCCAACTACATATTGAGCGCCCGCTTTCGCACCGCCAGCGCAGCCTCGCGCATGACCTCGGACAGTGATGGGTGCGGGT
GGCAGATCATGCCGATGTCC

Product: response regulator, signal receiver domain-containing protein (CheY-like)

Products: NA

Alternate protein names: Capsular synthesis regulator component C [H]

Number of amino acids: Translated: 150; Mature: 149

Protein sequence:

>150_residues
MPRTVSKPANNLPLPRVIVAEDHPVCLLVLEDQLKGIGGCEVVLCENGADALRALESGPAALLLTDLSLPGIEGLALARR
IRTGKAGQVAPDLPIVAITATAGPEERLACLEAGIGMVLTKPVSYETLQSVLGRYLGKDDQYDQYEQYDR

Sequences:

>Translated_150_residues
MPRTVSKPANNLPLPRVIVAEDHPVCLLVLEDQLKGIGGCEVVLCENGADALRALESGPAALLLTDLSLPGIEGLALARR
IRTGKAGQVAPDLPIVAITATAGPEERLACLEAGIGMVLTKPVSYETLQSVLGRYLGKDDQYDQYEQYDR
>Mature_149_residues
PRTVSKPANNLPLPRVIVAEDHPVCLLVLEDQLKGIGGCEVVLCENGADALRALESGPAALLLTDLSLPGIEGLALARRI
RTGKAGQVAPDLPIVAITATAGPEERLACLEAGIGMVLTKPVSYETLQSVLGRYLGKDDQYDQYEQYDR

Specific function: Member of the two-component regulatory system rcsC/rcsB involved in the regulation of the expression of genes involved in colanic acid capsule synthesis. Together with rcsF, rcsC probably functions as a membrane-associated protein kinase that phosphorylat

COG id: COG0784

COG function: function code T; FOG: CheY-like receiver

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI145693157, Length=139, Percent_Identity=33.0935251798561, Blast_Score=77, Evalue=5e-16,
Organism=Escherichia coli, GI1788191, Length=123, Percent_Identity=29.2682926829268, Blast_Score=63, Evalue=9e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011006
- InterPro:   IPR000014
- InterPro:   IPR004358
- InterPro:   IPR019017
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF09456 RcsC; PF00072 Response_reg [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 15992; Mature: 15860

Theoretical pI: Translated: 4.50; Mature: 4.50

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.7 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
2.7 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPRTVSKPANNLPLPRVIVAEDHPVCLLVLEDQLKGIGGCEVVLCENGADALRALESGPA
CCCCCCCCCCCCCCCEEEEECCCCEEEEEEECCCCCCCCEEEEEECCCHHHHHHHHCCCE
ALLLTDLSLPGIEGLALARRIRTGKAGQVAPDLPIVAITATAGPEERLACLEAGIGMVLT
EEEEEECCCCCCHHHHHHHHHHCCCCCCCCCCCCEEEEEECCCCHHHHHHHHCCCCEEEE
KPVSYETLQSVLGRYLGKDDQYDQYEQYDR
CCCCHHHHHHHHHHHCCCCCCCCHHHHCCC
>Mature Secondary Structure 
PRTVSKPANNLPLPRVIVAEDHPVCLLVLEDQLKGIGGCEVVLCENGADALRALESGPA
CCCCCCCCCCCCCCEEEEECCCCEEEEEEECCCCCCCCEEEEEECCCHHHHHHHHCCCE
ALLLTDLSLPGIEGLALARRIRTGKAGQVAPDLPIVAITATAGPEERLACLEAGIGMVLT
EEEEEECCCCCCHHHHHHHHHHCCCCCCCCCCCCEEEEEECCCCHHHHHHHHCCCCEEEE
KPVSYETLQSVLGRYLGKDDQYDQYEQYDR
CCCCHHHHHHHHHHHCCCCCCCCHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11677608; 12644504; 8626298 [H]