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The map label for this gene is yfdZ [H]

Identifier: 94313128

GI number: 94313128

Start: 785360

End: 786577

Strand: Direct

Name: yfdZ [H]

Synonym: Rmet_4201

Alternate gene names: 94313128

Gene position: 785360-786577 (Clockwise)

Preceding gene: 94313127

Following gene: 94313130

Centisome position: 30.44

GC content: 63.38

Gene sequence:

>1218_bases
ATGACTGCCGATTCCGGCAAGCGCCGCTTTGCGCGCATCGATCGTCTTCCCCCGTACGTTTTCAATATCACCGCCGAGCT
CAAGATGGCCGCCCGCCGCCGTGGCGAGGACATCATCGACATGAGCATGGGCAACCCCGATGGCGCCACGCCGCCGCATA
TCGTGGCCAAGCTCGTCGACGCCGCGCAGCGGCCGGACACGCACGGGTATTCGGCGTCGAAGGGCATCCCGCGCCTGCGT
CGCGCGATCTCGCACTGGTACCGCGAACGCTATGACGTCGATATCGATCCGGACAAGGAGGCGATTGTCACGATCGGCTC
GAAGGAAGGCCTTGCGCACCTGATGCTGGCCACGCTGGACCGTGGCGACACCGTGCTGGTGCCCGACCCCAGCTACCCGA
TCCACATCTATGGCGCGGTGATCGCGGGGGCAGACATCCGCTCAGTGCCGCTGACGCCGGGCATCGACTTCTTCGCCGAA
CTGGAACGCGCGATTCGTGGCAGCTACCCGAAGCCGAAGATGATCGTGCTGGGTTTCCCGTCCAATCCGACGGCGGCCTG
CGTGGAGCTCGATTTCTTCGAACGCGTGATTGCGCTGGCGCGCAAGCACGACATCTTCGTGGTGCACGACCTGGCTTATG
CCGATATCGTTTTCGATGGCTGGAAGGCGCCGTCGATCATGCAGGTGCCGGGCGCGAAGGACATCGCGGTGGAGTTCTTC
ACGCTGTCCAAGAGCTACAACATGGCGGGATGGCGGATCGGCTTCATGGTCGGCAATCCCGACCTTGTGGCCGCGCTGAC
GCGTATCAAGAGCTATCACGACTATGGCACGTTCACACCGCTGCAGGTGGCGGCGATCGCCGCGCTCGAGGGCGACCAAC
AGTGCGTGAAGGAAATTGCCGCCCAGTATCAGTCGCGCCGCGACGTGCTGGCACGCGGGCTGATCGAGTCGGGCTGGCCA
GTCGATATTCCAAAGGCTTCGATGTACATCTGGGCCCGTATCCCGGAACCCTATCGCGCGCTCGGCTCGCTAGAGTTTGC
CAAGCAACTGTTGGCCAAGGCCAAGGTATCGGTTTCCCCCGGTATCGGGTTTGGTGACTACGGCGATGAGTATGTGCGAT
TCGCGCTGATCGAGAACGAATCGCGTATCCGTCAGGCGGTGCGCGGGATCAAGGCGATGTTCCGCGCGGATGGGCTGGTG
ACGGCGCCAGGCGGCTGA

Upstream 100 bases:

>100_bases
GTGCGATTGCGCGCGTCTTGCTAAATTCAGTCCCCAGCGACCGAGACAACGGTCGCGACGTCGCTCGGACGGTTCCGGGC
GCTTACGTAAAGGACTCCAC

Downstream 100 bases:

>100_bases
TCTGCAGTTGGTTTTTTCCCCTCTTCCGCGAGCGGAAGAGGGGAGCCAGCAATCGGCAACTCCCAACCTCAGAAATATCC
CACGAACCGTTTCATGATCG

Product: aminotransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 405; Mature: 404

Protein sequence:

>405_residues
MTADSGKRRFARIDRLPPYVFNITAELKMAARRRGEDIIDMSMGNPDGATPPHIVAKLVDAAQRPDTHGYSASKGIPRLR
RAISHWYRERYDVDIDPDKEAIVTIGSKEGLAHLMLATLDRGDTVLVPDPSYPIHIYGAVIAGADIRSVPLTPGIDFFAE
LERAIRGSYPKPKMIVLGFPSNPTAACVELDFFERVIALARKHDIFVVHDLAYADIVFDGWKAPSIMQVPGAKDIAVEFF
TLSKSYNMAGWRIGFMVGNPDLVAALTRIKSYHDYGTFTPLQVAAIAALEGDQQCVKEIAAQYQSRRDVLARGLIESGWP
VDIPKASMYIWARIPEPYRALGSLEFAKQLLAKAKVSVSPGIGFGDYGDEYVRFALIENESRIRQAVRGIKAMFRADGLV
TAPGG

Sequences:

>Translated_405_residues
MTADSGKRRFARIDRLPPYVFNITAELKMAARRRGEDIIDMSMGNPDGATPPHIVAKLVDAAQRPDTHGYSASKGIPRLR
RAISHWYRERYDVDIDPDKEAIVTIGSKEGLAHLMLATLDRGDTVLVPDPSYPIHIYGAVIAGADIRSVPLTPGIDFFAE
LERAIRGSYPKPKMIVLGFPSNPTAACVELDFFERVIALARKHDIFVVHDLAYADIVFDGWKAPSIMQVPGAKDIAVEFF
TLSKSYNMAGWRIGFMVGNPDLVAALTRIKSYHDYGTFTPLQVAAIAALEGDQQCVKEIAAQYQSRRDVLARGLIESGWP
VDIPKASMYIWARIPEPYRALGSLEFAKQLLAKAKVSVSPGIGFGDYGDEYVRFALIENESRIRQAVRGIKAMFRADGLV
TAPGG
>Mature_404_residues
TADSGKRRFARIDRLPPYVFNITAELKMAARRRGEDIIDMSMGNPDGATPPHIVAKLVDAAQRPDTHGYSASKGIPRLRR
AISHWYRERYDVDIDPDKEAIVTIGSKEGLAHLMLATLDRGDTVLVPDPSYPIHIYGAVIAGADIRSVPLTPGIDFFAEL
ERAIRGSYPKPKMIVLGFPSNPTAACVELDFFERVIALARKHDIFVVHDLAYADIVFDGWKAPSIMQVPGAKDIAVEFFT
LSKSYNMAGWRIGFMVGNPDLVAALTRIKSYHDYGTFTPLQVAAIAALEGDQQCVKEIAAQYQSRRDVLARGLIESGWPV
DIPKASMYIWARIPEPYRALGSLEFAKQLLAKAKVSVSPGIGFGDYGDEYVRFALIENESRIRQAVRGIKAMFRADGLVT
APGG

Specific function: Unknown

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI56713254, Length=418, Percent_Identity=24.6411483253589, Blast_Score=116, Evalue=5e-26,
Organism=Homo sapiens, GI56713256, Length=418, Percent_Identity=24.6411483253589, Blast_Score=115, Evalue=5e-26,
Organism=Homo sapiens, GI95147551, Length=421, Percent_Identity=23.7529691211401, Blast_Score=110, Evalue=3e-24,
Organism=Homo sapiens, GI169881279, Length=421, Percent_Identity=23.7529691211401, Blast_Score=110, Evalue=3e-24,
Organism=Homo sapiens, GI169881281, Length=239, Percent_Identity=23.4309623430962, Blast_Score=77, Evalue=3e-14,
Organism=Escherichia coli, GI1788722, Length=396, Percent_Identity=82.5757575757576, Blast_Score=694, Evalue=0.0,
Organism=Escherichia coli, GI1786816, Length=368, Percent_Identity=23.6413043478261, Blast_Score=116, Evalue=2e-27,
Organism=Escherichia coli, GI1788627, Length=239, Percent_Identity=30.5439330543933, Blast_Score=97, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI17567369, Length=398, Percent_Identity=23.3668341708543, Blast_Score=114, Evalue=1e-25,
Organism=Caenorhabditis elegans, GI71994476, Length=316, Percent_Identity=25.6329113924051, Blast_Score=112, Evalue=3e-25,
Organism=Caenorhabditis elegans, GI71994472, Length=320, Percent_Identity=25.625, Blast_Score=112, Evalue=3e-25,
Organism=Saccharomyces cerevisiae, GI6322401, Length=399, Percent_Identity=19.2982456140351, Blast_Score=88, Evalue=2e-18,
Organism=Saccharomyces cerevisiae, GI6320317, Length=349, Percent_Identity=22.6361031518625, Blast_Score=74, Evalue=5e-14,
Organism=Drosophila melanogaster, GI28573069, Length=412, Percent_Identity=25.4854368932039, Blast_Score=124, Evalue=1e-28,
Organism=Drosophila melanogaster, GI24646114, Length=412, Percent_Identity=25.4854368932039, Blast_Score=124, Evalue=1e-28,
Organism=Drosophila melanogaster, GI28573067, Length=412, Percent_Identity=25.4854368932039, Blast_Score=124, Evalue=1e-28,
Organism=Drosophila melanogaster, GI28573065, Length=412, Percent_Identity=25.4854368932039, Blast_Score=124, Evalue=1e-28,
Organism=Drosophila melanogaster, GI18859735, Length=251, Percent_Identity=23.5059760956175, Blast_Score=73, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: 2.6.1.- [C]

Molecular weight: Translated: 44667; Mature: 44536

Theoretical pI: Translated: 8.55; Mature: 8.55

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTADSGKRRFARIDRLPPYVFNITAELKMAARRRGEDIIDMSMGNPDGATPPHIVAKLVD
CCCCCCHHHHHHHHCCCCEEEEEHHHHHHHHHHCCCCEEEECCCCCCCCCCHHHHHHHHH
AAQRPDTHGYSASKGIPRLRRAISHWYRERYDVDIDPDKEAIVTIGSKEGLAHLMLATLD
HHCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCCCCHHHHHHHHCC
RGDTVLVPDPSYPIHIYGAVIAGADIRSVPLTPGIDFFAELERAIRGSYPKPKMIVLGFP
CCCEEEECCCCCCEEEEEEEEECCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCEEEEECC
SNPTAACVELDFFERVIALARKHDIFVVHDLAYADIVFDGWKAPSIMQVPGAKDIAVEFF
CCCCCEEEEHHHHHHHHHHHHCCCEEEEECCCEEEEEECCCCCCCEEECCCCCCEEEEEE
TLSKSYNMAGWRIGFMVGNPDLVAALTRIKSYHDYGTFTPLQVAAIAALEGDQQCVKEIA
EECCCCCCCCEEEEEEECCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCHHHHHHHH
AQYQSRRDVLARGLIESGWPVDIPKASMYIWARIPEPYRALGSLEFAKQLLAKAKVSVSP
HHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHCCCCCC
GIGFGDYGDEYVRFALIENESRIRQAVRGIKAMFRADGLVTAPGG
CCCCCCCCCCEEEEEEECCHHHHHHHHHHHHHHHHCCCEEECCCC
>Mature Secondary Structure 
TADSGKRRFARIDRLPPYVFNITAELKMAARRRGEDIIDMSMGNPDGATPPHIVAKLVD
CCCCCHHHHHHHHCCCCEEEEEHHHHHHHHHHCCCCEEEECCCCCCCCCCHHHHHHHHH
AAQRPDTHGYSASKGIPRLRRAISHWYRERYDVDIDPDKEAIVTIGSKEGLAHLMLATLD
HHCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCCCCHHHHHHHHCC
RGDTVLVPDPSYPIHIYGAVIAGADIRSVPLTPGIDFFAELERAIRGSYPKPKMIVLGFP
CCCEEEECCCCCCEEEEEEEEECCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCEEEEECC
SNPTAACVELDFFERVIALARKHDIFVVHDLAYADIVFDGWKAPSIMQVPGAKDIAVEFF
CCCCCEEEEHHHHHHHHHHHHCCCEEEEECCCEEEEEECCCCCCCEEECCCCCCEEEEEE
TLSKSYNMAGWRIGFMVGNPDLVAALTRIKSYHDYGTFTPLQVAAIAALEGDQQCVKEIA
EECCCCCCCCEEEEEEECCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCHHHHHHHH
AQYQSRRDVLARGLIESGWPVDIPKASMYIWARIPEPYRALGSLEFAKQLLAKAKVSVSP
HHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHCCCCCC
GIGFGDYGDEYVRFALIENESRIRQAVRGIKAMFRADGLVTAPGG
CCCCCCCCCCEEEEEEECCHHHHHHHHHHHHHHHHCCCEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: Pyridoxal Phosphate. [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9205837; 9278503 [H]