Click here to switch to the map view.

The map label for this gene is lrhA [H]

Identifier: 94313103

GI number: 94313103

Start: 761848

End: 762744

Strand: Reverse

Name: lrhA [H]

Synonym: Rmet_4176

Alternate gene names: 94313103

Gene position: 762744-761848 (Counterclockwise)

Preceding gene: 94313106

Following gene: 94313101

Centisome position: 29.56

GC content: 66.11

Gene sequence:

>897_bases
TTGTTGACTGCGATCGGATTTACCGATGACAATGCGGCGATGCTCAATCCCGTTTGGATCCAGACTTTCGCAACGGTGGC
CACCGCGCGCAGCTTTACCGACGCGGGGCGTCAGCTTGGCCTGTCGCAATCGTCGGTCAGCGACCATATCCGCCGGCTCG
AAGGCAGCGTGAGCCGACGGCTGTTTGTGCGCGATACCCACTCGCTGGCGCTGACACCCGATGGCGAAGCCCTGCTCGTT
CATGCCCGGCTGATTCTCGAATCCCTGGCCCGTGCCGAATCCCAGTTCAGCGGACCGCGCCTGCAGGGGCGCGTGCGCCT
TGGCACCTCCGAAGACTTGGCGCAGGGTCCCCTGCCGAATGTGCTGGCTGCATTCCGCGCCACGCATCCGGACGTGGAGC
TCGAGATCACCATCGGCATGACCAGCAAGCTGTACGAGTGGATGGAAGCGGGCACGCTGGACCTCATCGTCGGCAAGCGG
CGCGAAGGCGAGCGGCGCGGCGTGCCCCTTTTCCGTGGCCGGCTTGAATGGCTGGCGCGGCCCGGTACGGTTGTGGATGT
GCGTCAGCCTCTACCGCTGATCCTCGTGAACGAACCGAGCGTGACGCGCTCCGTGGTGCTGGACACGCTGGCCAAGAACG
GCTGGCGCTGGCGCGTCGTGTGCACCAGCAGTAGTCATTCCGGATGCATCGCAGCGGCGCGCGGCGGGCTCGGCATTACC
GTACGGGCCGAGAATCTGACCGGCGGCGGTCTGGTGCCACCGGTCAATTTCGATGCCCTGCCAGCACTGCCGGACGTGGA
GTTCATCACGCTGGCCGCACGCCGGCTCACCGAGCCGGCCGACACGCTGCTGCAACTGATTCGCAAGAGCGACCTGCGCG
CCGCGCGGGTCGATTGA

Upstream 100 bases:

>100_bases
ACGCATAGGCAATTCTTGATGGGGCGGCGTCAGTCCGGGTAATCCCGGAGACGTTCGAGCATGGTACCTAGCGGACACCC
CATCGGGAACCCCTCTGGCT

Downstream 100 bases:

>100_bases
TGCCTGCTTAGGCTGGCAACGCGCCCAGCGCCTGATAGGCGGTCAGCAGGTGATAAGGCGTGGTGGAAGGCATCTCCGCT
CGCACGACCATACCATCGGG

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 298; Mature: 298

Protein sequence:

>298_residues
MLTAIGFTDDNAAMLNPVWIQTFATVATARSFTDAGRQLGLSQSSVSDHIRRLEGSVSRRLFVRDTHSLALTPDGEALLV
HARLILESLARAESQFSGPRLQGRVRLGTSEDLAQGPLPNVLAAFRATHPDVELEITIGMTSKLYEWMEAGTLDLIVGKR
REGERRGVPLFRGRLEWLARPGTVVDVRQPLPLILVNEPSVTRSVVLDTLAKNGWRWRVVCTSSSHSGCIAAARGGLGIT
VRAENLTGGGLVPPVNFDALPALPDVEFITLAARRLTEPADTLLQLIRKSDLRAARVD

Sequences:

>Translated_298_residues
MLTAIGFTDDNAAMLNPVWIQTFATVATARSFTDAGRQLGLSQSSVSDHIRRLEGSVSRRLFVRDTHSLALTPDGEALLV
HARLILESLARAESQFSGPRLQGRVRLGTSEDLAQGPLPNVLAAFRATHPDVELEITIGMTSKLYEWMEAGTLDLIVGKR
REGERRGVPLFRGRLEWLARPGTVVDVRQPLPLILVNEPSVTRSVVLDTLAKNGWRWRVVCTSSSHSGCIAAARGGLGIT
VRAENLTGGGLVPPVNFDALPALPDVEFITLAARRLTEPADTLLQLIRKSDLRAARVD
>Mature_298_residues
MLTAIGFTDDNAAMLNPVWIQTFATVATARSFTDAGRQLGLSQSSVSDHIRRLEGSVSRRLFVRDTHSLALTPDGEALLV
HARLILESLARAESQFSGPRLQGRVRLGTSEDLAQGPLPNVLAAFRATHPDVELEITIGMTSKLYEWMEAGTLDLIVGKR
REGERRGVPLFRGRLEWLARPGTVVDVRQPLPLILVNEPSVTRSVVLDTLAKNGWRWRVVCTSSSHSGCIAAARGGLGIT
VRAENLTGGGLVPPVNFDALPALPDVEFITLAARRLTEPADTLLQLIRKSDLRAARVD

Specific function: Not known, does not seem to act on the proton translocating NADH dehydrogenase genes (nuoA-N) which are part of the lrhA operon [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1788626, Length=250, Percent_Identity=30.8, Blast_Score=120, Evalue=1e-28,
Organism=Escherichia coli, GI1790208, Length=145, Percent_Identity=34.4827586206897, Blast_Score=76, Evalue=3e-15,
Organism=Escherichia coli, GI1787601, Length=170, Percent_Identity=30, Blast_Score=75, Evalue=6e-15,
Organism=Escherichia coli, GI1788887, Length=160, Percent_Identity=33.125, Blast_Score=66, Evalue=3e-12,
Organism=Escherichia coli, GI1788748, Length=287, Percent_Identity=24.390243902439, Blast_Score=66, Evalue=3e-12,
Organism=Escherichia coli, GI1787806, Length=158, Percent_Identity=27.8481012658228, Blast_Score=65, Evalue=4e-12,
Organism=Escherichia coli, GI1787589, Length=136, Percent_Identity=33.0882352941176, Blast_Score=64, Evalue=8e-12,
Organism=Escherichia coli, GI1788296, Length=223, Percent_Identity=28.2511210762332, Blast_Score=62, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 32437; Mature: 32437

Theoretical pI: Translated: 9.42; Mature: 9.42

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLTAIGFTDDNAAMLNPVWIQTFATVATARSFTDAGRQLGLSQSSVSDHIRRLEGSVSRR
CEEEEEECCCCCEEECHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCE
LFVRDTHSLALTPDGEALLVHARLILESLARAESQFSGPRLQGRVRLGTSEDLAQGPLPN
EEEEECCEEEECCCCCEEEHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCHHHHCCCCHH
VLAAFRATHPDVELEITIGMTSKLYEWMEAGTLDLIVGKRREGERRGVPLFRGRLEWLAR
HHHHHHCCCCCEEEEEEECCHHHHHHHHHCCCEEEEECCCCCCCCCCCCHHHHHHHHHCC
PGTVVDVRQPLPLILVNEPSVTRSVVLDTLAKNGWRWRVVCTSSSHSGCIAAARGGLGIT
CCCEEEECCCCCEEEECCCCHHHHHHHHHHHCCCCEEEEEEECCCCCCEEEEECCCEEEE
VRAENLTGGGLVPPVNFDALPALPDVEFITLAARRLTEPADTLLQLIRKSDLRAARVD
EEECCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHCCCCEECCC
>Mature Secondary Structure
MLTAIGFTDDNAAMLNPVWIQTFATVATARSFTDAGRQLGLSQSSVSDHIRRLEGSVSRR
CEEEEEECCCCCEEECHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCE
LFVRDTHSLALTPDGEALLVHARLILESLARAESQFSGPRLQGRVRLGTSEDLAQGPLPN
EEEEECCEEEECCCCCEEEHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCHHHHCCCCHH
VLAAFRATHPDVELEITIGMTSKLYEWMEAGTLDLIVGKRREGERRGVPLFRGRLEWLAR
HHHHHHCCCCCEEEEEEECCHHHHHHHHHCCCEEEEECCCCCCCCCCCCHHHHHHHHHCC
PGTVVDVRQPLPLILVNEPSVTRSVVLDTLAKNGWRWRVVCTSSSHSGCIAAARGGLGIT
CCCEEEECCCCCEEEECCCCHHHHHHHHHHHCCCCEEEEEEECCCCCCEEEEECCCEEEE
VRAENLTGGGLVPPVNFDALPALPDVEFITLAARRLTEPADTLLQLIRKSDLRAARVD
EEECCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHCCCCEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]